| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mitsutaka Yamamoto, Guiping Yang, Chull Hong, Jing Liu, Eric Holle, Xianzhong Yu, Thomas Wagner, Stephen F Vatner, Junichi Sadoshim. Inhibition of endogenous thioredoxin in the heart increases oxidative stress and cardiac hypertrophy. The Journal of clinical investigation. vol 112. issue 9. 2003-12-03. PMID:14597765. |
intraperitoneal injection of n-2-mercaptopropionyl glycine, an antioxidant, normalized cardiac hypertrophy in tg-dn-trx1 mice. |
2003-12-03 |
2023-08-12 |
mouse |
| David Burton, Hassan Abdulrazzak, Adam Knott, Kathryn Elliott, Charles Redwood, Hugh Watkins, Steven Marston, Chris Ashle. Two mutations in troponin I that cause hypertrophic cardiomyopathy have contrasting effects on cardiac muscle contractility. The Biochemical journal. vol 362. issue Pt 2. 2002-04-03. PMID:11853553. |
we investigated the effects of two mutations in human cardiac troponin i, arg(145)-->gly and gly(203)-->ser, that are reported to cause familial hypertrophic cardiomyopathy. |
2002-04-03 |
2023-08-12 |
human |
| David Burton, Hassan Abdulrazzak, Adam Knott, Kathryn Elliott, Charles Redwood, Hugh Watkins, Steven Marston, Chris Ashle. Two mutations in troponin I that cause hypertrophic cardiomyopathy have contrasting effects on cardiac muscle contractility. The Biochemical journal. vol 362. issue Pt 2. 2002-04-03. PMID:11853553. |
thus these two mutations each result in hypertrophic cardiomyopathy, but have opposite effects on the overall contractility of the muscle in the systems we investigated, indicating either that we have not yet identified the relevant alteration in contractility for the gly(203)->ser mutation, or that the disease does not result directly from any particular alteration in contractility. |
2002-04-03 |
2023-08-12 |
human |
| Moto-o Date, Takashi Morita, Nobushige Yamashita, Kazuhiko Nishida, Osamu Yamaguchi, Yoshiharu Higuchi, Shinichi Hirotani, Yasushi Matsumura, Masatsugu Hori, Michihiko Tada, Kinya Ots. The antioxidant N-2-mercaptopropionyl glycine attenuates left ventricular hypertrophy in in vivo murine pressure-overload model. Journal of the American College of Cardiology. vol 39. issue 5. 2002-03-20. PMID:11869860. |
the antioxidant n-2-mercaptopropionyl glycine attenuates left ventricular hypertrophy in in vivo murine pressure-overload model. |
2002-03-20 |
2023-08-12 |
Not clear |
| Moto-o Date, Takashi Morita, Nobushige Yamashita, Kazuhiko Nishida, Osamu Yamaguchi, Yoshiharu Higuchi, Shinichi Hirotani, Yasushi Matsumura, Masatsugu Hori, Michihiko Tada, Kinya Ots. The antioxidant N-2-mercaptopropionyl glycine attenuates left ventricular hypertrophy in in vivo murine pressure-overload model. Journal of the American College of Cardiology. vol 39. issue 5. 2002-03-20. PMID:11869860. |
in order to identify the role of reactive oxygen species (ros) in cardiac hypertrophy, we examined the effect of n-2-mercaptopropionyl glycine (mpg) on cardiac hypertrophy. |
2002-03-20 |
2023-08-12 |
Not clear |
| H Kamiya, K Okumura, M Ito, H Matsui, Y Saburi, K Hayashi, T Hayakaw. Antioxidant changes in the hypertrophied heart due to energy metabolic disorder. Basic research in cardiology. vol 96. issue 5. 2002-03-12. PMID:11605989. |
to determine whether antioxidants affect the pathogenesis of hypertrophy in this model, long-term treatments of vitamin e and 2-mercaptopropionyl glycine were performed. |
2002-03-12 |
2023-08-12 |
mouse |
| S Raha, F Merante, E Shoubridge, A T Myint, I Tein, L Benson, T Johns, B H Robinso. Repopulation of rho0 cells with mitochondria from a patient with a mitochondrial DNA point mutation in tRNA(Gly) results in respiratory chain dysfunction. Human mutation. vol 13. issue 3. 1999-07-13. PMID:10090480. |
a fibroblast cell line carrying a mutation in its mtdna at position 9997 in the gene encoding trna glycine was obtained from a patient with hypertrophic cardiomyopathy. |
1999-07-13 |
2023-08-12 |
Not clear |
| S Arai, R Matsuoka, K Hirayama, H Sakurai, M Tamura, T Ozawa, M Kimura, S Imamura, Y Furutani, K Joh-. Missense mutation of the beta-cardiac myosin heavy-chain gene in hypertrophic cardiomyopathy. American journal of medical genetics. vol 58. issue 3. 1996-01-30. PMID:8533830. |
we describe a missense mutation of the beta-cardiac myosin heavy chain (mhc) gene, a g to t transversion (741 gly-->trp) identified by direct sequencing of exon 20 in four individuals affected with familial hypertrophic cardiomyopathy. |
1996-01-30 |
2023-08-12 |
Not clear |
| F Merante, I Tein, L Benson, B H Robinso. Maternally inherited hypertrophic cardiomyopathy due to a novel T-to-C transition at nucleotide 9997 in the mitochondrial tRNA(glycine) gene. American journal of human genetics. vol 55. issue 3. 1994-10-06. PMID:8079988. |
maternally inherited hypertrophic cardiomyopathy due to a novel t-to-c transition at nucleotide 9997 in the mitochondrial trna(glycine) gene. |
1994-10-06 |
2023-08-12 |
human |
| S Rosen, F H Epstein, M Brezi. Determinants of intrarenal oxygenation: factors in acute renal failure. Renal failure. vol 14. issue 3. 1992-09-22. PMID:1509164. |
with hyperfiltration (induced by glycine or renal hypertrophy) and the pursuant increase in transport related o2 demand, hypoxic mtal inner stripe injury becomes prominent. |
1992-09-22 |
2023-08-11 |
rat |
| S N Heyman, M Brezis, F H Epstein, K Spokes, S Rose. Effect of glycine and hypertrophy on renal outer medullary hypoxic injury in ischemia reflow and contrast nephropathy. American journal of kidney diseases : the official journal of the National Kidney Foundation. vol 19. issue 6. 1992-06-26. PMID:1595707. |
effect of glycine and hypertrophy on renal outer medullary hypoxic injury in ischemia reflow and contrast nephropathy. |
1992-06-26 |
2023-08-11 |
rat |
| J W Robinson, J Borgeaud, V Mirkovitc. Glycine transport in hypertrophic rat kidneys. Biomedicine / [publiee pour l'A.A.I.C.I.G.]. vol 19. issue 1. 1973-08-09. PMID:4710246. |
glycine transport in hypertrophic rat kidneys. |
1973-08-09 |
2023-08-11 |
rat |