| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Patricio O'Donnel. Adolescent maturation of cortical dopamine. Neurotoxicity research. vol 18. issue 3-4. 2011-09-15. PMID:20151241. |
in adult rats with a neonatal ventral hippocampal lesion (nvhl), an extensively studied developmental model of schizophrenia, the maturation in the d2 modulation of interneuron physiology fails to occur, rendering a disinhibited prefrontal cortex. |
2011-09-15 |
2023-08-12 |
rat |
| Cheng B Lu, James B Hamilton, Andrew D Powell, Emil C Toescu, Martin Vreugdenhi. Effect of ageing on CA3 interneuron sAHP and gamma oscillations is activity-dependent. Neurobiology of aging. vol 32. issue 5. 2011-08-17. PMID:19523715. |
the age-dependent and stimulation-dependent increase in basal [ca(2+)](i), firing-induced [ca(2+)](i) transient and associated afterhyperpolarisation may reduce interneuron excitability and contribute to an age-dependent impairment of hippocampal gamma oscillations. |
2011-08-17 |
2023-08-12 |
mouse |
| Bi-Wen Peng, Jason A Justice, Kun Zhang, Jun-Xu Li, Xiao-Hua He, Russell M Sanche. Gabapentin promotes inhibition by enhancing hyperpolarization-activated cation currents and spontaneous firing in hippocampal CA1 interneurons. Neuroscience letters. vol 494. issue 1. 2011-08-15. PMID:21352896. |
i(h) also regulates excitability in some types of hippocampal interneuron that provide synaptic inhibition to ca1 pyramidal neurons, suggesting that global pharmacological i(h) enhancement could have more complex effects on the local synaptic network. |
2011-08-15 |
2023-08-12 |
rat |
| T J Williams, T A Milne. Delta opioid receptors colocalize with corticotropin releasing factor in hippocampal interneurons. Neuroscience. vol 179. 2011-07-13. PMID:21277946. |
here, hippocampal sections of male and cycling female adult sprague-dawley rats were processed for immunolabeling using antisera directed against the dor and crf peptide, as well as interneuron subtype markers somatostatin or parvalbumin, and analyzed by fluorescence and electron microscopy. |
2011-07-13 |
2023-08-12 |
rat |
| Tope Lanre-Amos, Bernat Kocsi. Hippocampal oscillations in the rodent model of schizophrenia induced by amygdala GABA receptor blockade. Frontiers in psychiatry. vol 1. 2011-04-22. PMID:21308001. |
the aim of this study was to examine the capability of hippocampal networks to generate oscillations in a rat model previously shown to reproduce the stereotypic structural alterations of the hippocampal interneuron circuit seen in schizophrenic patients. |
2011-04-22 |
2023-08-12 |
rat |
| Tope Lanre-Amos, Bernat Kocsi. Hippocampal oscillations in the rodent model of schizophrenia induced by amygdala GABA receptor blockade. Frontiers in psychiatry. vol 1. 2011-04-22. PMID:21308001. |
this model uses injection of gaba-a receptor antagonist picrotoxin into the basolateral amygdala which causes cell-type specific disruption of interneuron signaling in the hippocampus. |
2011-04-22 |
2023-08-12 |
rat |
| Timothy B Johnstone, Zhenglin Gu, Ryan F Yoshimura, Anne-Sophie Villegier, Derk J Hogenkamp, Edward R Whittemore, Jin-Cheng Huang, Minhtam B Tran, James D Belluzzi, Jerrel L Yakel, Kelvin W Ge. Allosteric modulation of related ligand-gated ion channels synergistically induces long-term potentiation in the hippocampus and enhances cognition. The Journal of pharmacology and experimental therapeutics. vol 336. issue 3. 2011-04-21. PMID:21159751. |
postsynaptic α7 nachrs in the hippocampus regulate inhibitory gabaergic interneuron activity required for synchronization of pyramidal neurons in the ca1, whereas presynaptic α7 nachrs regulate glutamate release. |
2011-04-21 |
2023-08-12 |
rat |
| Attila I Gulyás, Gergely G Szabó, István Ulbert, Noémi Holderith, Hannah Monyer, Ferenc Erdélyi, Gábor Szabó, Tamás F Freund, Norbert Hájo. Parvalbumin-containing fast-spiking basket cells generate the field potential oscillations induced by cholinergic receptor activation in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 45. 2010-12-13. PMID:21068319. |
here, we examined the contribution of the three perisomatic interneuron types--the parvalbumin-containing fast-spiking basket cells (fsbcs) and axo-axonic cells (aacs), as well as the cholecystokinin-containing regular-spiking basket cells (rsbcs) to cholinergically induced oscillations in hippocampal slices, a rhythmic activity that captures several features of the gamma oscillations recorded in vivo. |
2010-12-13 |
2023-08-12 |
Not clear |
| I Zipancic, M E Calcagnotto, M Piquer-Gil, L E Mello, M Alvarez-Dolad. Transplant of GABAergic precursors restores hippocampal inhibitory function in a mouse model of seizure susceptibility. Cell transplantation. vol 19. issue 5. 2010-11-22. PMID:20144261. |
thus, as proof of principle, we grafted mge-derived cells into a mouse model of seizure susceptibility caused by specific elimination of gabaergic interneuron subpopulations in the mouse hippocampus after injection of the neurotoxic saporin conjugated to substance p (ssp-sap). |
2010-11-22 |
2023-08-12 |
mouse |
| Nathalie T Sanon, Joe Guillaume Pelletier, Lionel Carmant, Jean-Claude Lacaill. Interneuron subtype specific activation of mGluR1/5 during epileptiform activity in hippocampus. Epilepsia. vol 51. issue 8. 2010-10-22. PMID:20698876. |
interneuron subtype specific activation of mglur1/5 during epileptiform activity in hippocampus. |
2010-10-22 |
2023-08-12 |
Not clear |
| Jhumku D Kohtz, Emily G Berghof. Regulatory long non-coding RNAs and neuronal disorders. Physiology & behavior. vol 100. issue 3. 2010-10-12. PMID:20097218. |
this commentary discusses the intersection of these two fields, a corollary to the finding that adult hippocampal gabaergic interneuron development is controlled by an embryonic non-coding rna during development. |
2010-10-12 |
2023-08-12 |
Not clear |
| Ariane Croce, Joe Guillaume Pelletier, Maylis Tartas, Jean-Claude Lacaill. Afferent-specific properties of interneuron synapses underlie selective long-term regulation of feedback inhibitory circuits in CA1 hippocampus. The Journal of physiology. vol 588. issue Pt 12. 2010-10-04. PMID:20403974. |
afferent-specific properties of interneuron synapses underlie selective long-term regulation of feedback inhibitory circuits in ca1 hippocampus. |
2010-10-04 |
2023-08-12 |
Not clear |
| Michael I Daw, Kenneth A Pelkey, Ramesh Chittajallu, Chris J McBai. Presynaptic kainate receptor activation preserves asynchronous GABA release despite the reduction in synchronous release from hippocampal cholecystokinin interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 33. 2010-09-03. PMID:20720128. |
inhibitory synaptic transmission in the hippocampus in mediated by a wide variety of different interneuron classes which are assumed to play different roles in network activity. |
2010-09-03 |
2023-08-12 |
Not clear |
| Ashok K Shetty, Bharathi Hattiangady, Muddanna S Ra. Vulnerability of hippocampal GABA-ergic interneurons to kainate-induced excitotoxic injury during old age. Journal of cellular and molecular medicine. vol 13. issue 8B. 2010-07-19. PMID:20141618. |
studies in young adult animals further suggest that hippocampal gad-67+ interneuron population is highly vulnerable to excitotoxic injury. |
2010-07-19 |
2023-08-12 |
rat |
| Ashok K Shetty, Bharathi Hattiangady, Muddanna S Ra. Vulnerability of hippocampal GABA-ergic interneurons to kainate-induced excitotoxic injury during old age. Journal of cellular and molecular medicine. vol 13. issue 8B. 2010-07-19. PMID:20141618. |
contrastingly, there was no significant change in gad-67+ interneuron population in any of the hippocampal layers and sub-fields following similar injury in aged animals. |
2010-07-19 |
2023-08-12 |
rat |
| Ashok K Shetty, Bharathi Hattiangady, Muddanna S Ra. Vulnerability of hippocampal GABA-ergic interneurons to kainate-induced excitotoxic injury during old age. Journal of cellular and molecular medicine. vol 13. issue 8B. 2010-07-19. PMID:20141618. |
interestingly, because of the age-related disparity in vulnerability of interneurons to injury, the surviving gad-67+ interneuron population in the injured aged hippocampus remained comparable to that observed in the injured adult hippocampus despite enduring significant reductions in interneuron number with aging. |
2010-07-19 |
2023-08-12 |
rat |
| Ashok K Shetty, Bharathi Hattiangady, Muddanna S Ra. Vulnerability of hippocampal GABA-ergic interneurons to kainate-induced excitotoxic injury during old age. Journal of cellular and molecular medicine. vol 13. issue 8B. 2010-07-19. PMID:20141618. |
persistence of gad-67+ interneuron population in the injured aged hippocampus likely reflects an age-related change in the response of gad-67+ interneurons to excitotoxic hippocampal injury. |
2010-07-19 |
2023-08-12 |
rat |
| Wiebke Nissen, Andras Szabo, Jozsef Somogyi, Peter Somogyi, Karri P Lams. Cell type-specific long-term plasticity at glutamatergic synapses onto hippocampal interneurons expressing either parvalbumin or CB1 cannabinoid receptor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 4. 2010-07-08. PMID:20107060. |
different gabaergic interneuron types have specific roles in hippocampal function, and anatomical as well as physiological features vary greatly between interneuron classes. |
2010-07-08 |
2023-08-12 |
Not clear |
| Zsófia Maglóczk. Sprouting in human temporal lobe epilepsy: excitatory pathways and axons of interneurons. Epilepsy research. vol 89. issue 1. 2010-06-18. PMID:20149961. |
fate of functionally different hippocampal interneuron types has been investigated in surgically removed hippocampi of therapy resistant human tle patients. |
2010-06-18 |
2023-08-12 |
human |
| Zsófia Maglóczk. Sprouting in human temporal lobe epilepsy: excitatory pathways and axons of interneurons. Epilepsy research. vol 89. issue 1. 2010-06-18. PMID:20149961. |
our results suggest that an intense synaptic reorganization takes place in the epileptic hippocampus, including axonal sprouting of certain interneuron types, both in sclerotic and non-sclerotic tissue. |
2010-06-18 |
2023-08-12 |
human |