| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuxin Ma, Mali Zhan, Lisi OuYang, Youlan Li, Si Chen, Jiajia Wu, Jiachang Chen, Cheng Luo, Wanlong Le. The effects of unilateral 6-OHDA lesion in medial forebrain bundle on the motor, cognitive dysfunctions and vulnerability of different striatal interneuron types in rats. Behavioural brain research. vol 266. 2014-12-12. PMID:24613235. |
the effects of unilateral 6-ohda lesion in medial forebrain bundle on the motor, cognitive dysfunctions and vulnerability of different striatal interneuron types in rats. |
2014-12-12 |
2023-08-12 |
rat |
| Gregory B Bissonette, Mihyun H Bae, Tejas Suresh, David E Jaffe, Elizabeth M Powel. Prefrontal cognitive deficits in mice with altered cerebral cortical GABAergic interneurons. Behavioural brain research. vol 259. 2014-08-04. PMID:24211452. |
factors that govern the interneuron populations have been identified, demonstrating that a single gene mutation may globally affect forebrain structures or a single area. |
2014-08-04 |
2023-08-12 |
mouse |
| Hanna E Stevens, Tina Su, Yuchio Yanagawa, Flora M Vaccarin. Prenatal stress delays inhibitory neuron progenitor migration in the developing neocortex. Psychoneuroendocrinology. vol 38. issue 4. 2014-04-10. PMID:22910687. |
significant changes in dlx2, nkx2.1 and their downstream target erbb4, transcription factors which regulate interneuron migration, were found within the prenatally stressed developing forebrain, while no differences were seen in mash1, a determinant of interneuron fate, bdnf, a maturation factor for gabaergic cells or fgf2, an early growth/differentiation factor. |
2014-04-10 |
2023-08-12 |
mouse |
| Yan Liu, Huisheng Liu, Conall Sauvey, Lin Yao, Ewa D Zarnowska, Su-Chun Zhan. Directed differentiation of forebrain GABA interneurons from human pluripotent stem cells. Nature protocols. vol 8. issue 9. 2014-03-26. PMID:23928500. |
availability of enriched functional human forebrain gaba interneurons, especially those from people affected by gaba interneuron deficit disease, will be instrumental to the investigation of disease pathogenesis and development of therapeutics. |
2014-03-26 |
2023-08-12 |
human |
| David Tsui, Anastassia Voronova, Denis Gallagher, David R Kaplan, Freda D Miller, Jing Wan. CBP regulates the differentiation of interneurons from ventral forebrain neural precursors during murine development. Developmental biology. vol 385. issue 2. 2014-03-06. PMID:24247009. |
moreover, we show that levels of the neurotransmitter synthesis enzyme gad67, which is expressed in inhibitory interneurons, are decreased in the dorsal and ventral forebrain of neonatal cbp(+/-) mice, indicating that cbp plays a role in regulating interneuron development in vivo. |
2014-03-06 |
2023-08-12 |
mouse |
| David Tsui, Anastassia Voronova, Denis Gallagher, David R Kaplan, Freda D Miller, Jing Wan. CBP regulates the differentiation of interneurons from ventral forebrain neural precursors during murine development. Developmental biology. vol 385. issue 2. 2014-03-06. PMID:24247009. |
thus, cbp normally acts to ensure the differentiation of appropriate numbers of forebrain interneurons, and when its levels are decreased, this causes deficits in interneuron development, providing a potential explanation for the epilepsy seen in individuals with rts. |
2014-03-06 |
2023-08-12 |
mouse |
| Asif M Maroof, Sotirios Keros, Jennifer A Tyson, Shui-Wang Ying, Yosif M Ganat, Florian T Merkle, Becky Liu, Adam Goulburn, Edouard G Stanley, Andrew G Elefanty, Hans Ruedi Widmer, Kevin Eggan, Peter A Goldstein, Stewart A Anderson, Lorenz Stude. Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells. Cell stem cell. vol 12. issue 5. 2014-02-21. PMID:23642365. |
our study defines the signals sufficient for modeling human ventral forebrain development in vitro and lays the foundation for studying cortical interneuron involvement in human disease pathology. |
2014-02-21 |
2023-08-12 |
human |
| Myrto Denaxa, Melanie Kalaitzidou, Anna Garefalaki, Angeliki Achimastou, Reena Lasrado, Tamara Maes, Vassilis Pachni. Maturation-promoting activity of SATB1 in MGE-derived cortical interneurons. Cell reports. vol 2. issue 5. 2013-05-09. PMID:23142661. |
the generation of cortical interneuron subtypes is controlled by genetic programs that are activated in the ventral forebrain and unfold during the prolonged period of inhibitory neuron development. |
2013-05-09 |
2023-08-12 |
Not clear |
| Hedong Li, Anna T Hader, Yu R Han, Joseph A Wong, Joanne Babiarz, Christopher L Ricupero, Sasha Blue Godfrey, John P Corradi, Myles Fennell, Ronald P Hart, Mark R Plummer, Martin Grume. Isolation of a novel rat neural progenitor clone that expresses Dlx family transcription factors and gives rise to functional GABAergic neurons in culture. Developmental neurobiology. vol 72. issue 6. 2012-09-28. PMID:21913335. |
the results suggest that the ge6 clone, which is ventrally derived from the ge, resembles gabaergic interneuron progenitors that migrate into the developing forebrain. |
2012-09-28 |
2023-08-12 |
rat |
| Rita Lopes, Nicole Verhey van Wijk, Guilherme Neves, Vassilis Pachni. Transcription factor LIM homeobox 7 (Lhx7) maintains subtype identity of cholinergic interneurons in the mammalian striatum. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 8. 2012-04-12. PMID:22315402. |
by demonstrating that the switch between alternative striatal interneuron fates depends on persistent activity of a single transcription factor, we provide evidence that the intrinsic plasticity of mammalian forebrain neuronal subtypes is maintained after the initial specification and lineage commitment and possibly throughout life. |
2012-04-12 |
2023-08-12 |
mouse |
| M Elizabeth Ros. Cell cycle regulation and interneuron production. Developmental neurobiology. vol 71. issue 1. 2011-11-29. PMID:21154905. |
recent observations pertinent to interneuron genesis in the ventral forebrain, especially in the medial ganglionic eminence, indicate similarities to cerebral cortical neurogenesis and hint at some interesting differences between ventral and dorsal telencephalon progenitors. |
2011-11-29 |
2023-08-12 |
Not clear |
| Diego Garcia-Gonzalez, Fernando de Castr. [How is the sense of smell connected? Cellular and molecular mechanisms guiding the development of the synaptic connections from the nose to the cortex (II)]. Revista de neurologia. vol 52. issue 9. 2011-08-15. PMID:21484727. |
we shall also review the mechanisms involved in the migration of the interneuron precursors from the sub-ventricular area of the forebrain to the olfactory bulb, which is another crucial event in the development of this system. |
2011-08-15 |
2023-08-12 |
Not clear |
| Huan Liu, Kathleen M Guthri. Neuronal replacement in the injured olfactory bulb. Experimental neurology. vol 228. issue 2. 2011-06-17. PMID:21310147. |
the adult forebrain subventricular zone contains neural stem cells that produce neurons destined for the olfactory bulb, where interneuron populations turnover throughout life. |
2011-06-17 |
2023-08-12 |
Not clear |
| Ryan B MacDonald, Mélanie Debiais-Thibaud, Jared Coffin Talbot, Marc Ekke. The relationship between dlx and gad1 expression indicates highly conserved genetic pathways in the zebrafish forebrain. Developmental dynamics : an official publication of the American Association of Anatomists. vol 239. issue 8. 2010-11-23. PMID:20658694. |
our results indicate the dlx genes are regulated by an evolutionarily conserved genetic pathway and may play a role in gabaergic interneuron differentiation in the zebrafish forebrain. |
2010-11-23 |
2023-08-12 |
mouse |
| K L Eagleson, M C Gravielle, L J Schlueter McFadyen-Ketchum, S J Russek, D H Farb, P Levit. Genetic disruption of the autism spectrum disorder risk gene PLAUR induces GABAA receptor subunit changes. Neuroscience. vol 168. issue 3. 2010-09-21. PMID:20381588. |
for all subunits, no changes were observed in forebrain regions where gabaergic interneuron numbers are normal. |
2010-09-21 |
2023-08-12 |
mouse |
| Asif Mirza Maroof, Keith Brown, Song-Hai Shi, Lorenz Studer, Stewart A Anderso. Prospective isolation of cortical interneuron precursors from mouse embryonic stem cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 13. 2010-04-22. PMID:20357117. |
this work demonstrates that forebrain neuronal subtypes with complex traits can be generated from embryonic stem cells, and provides a novel approach to the study of cortical interneuron development and to the establishment of cell-based therapies for neurological disease. |
2010-04-22 |
2023-08-12 |
mouse |
| Sofia Fertuzinhos, Zeljka Krsnik, Yuka Imamura Kawasawa, Mladen-Roko Rasin, Kenneth Y Kwan, Jie-Guang Chen, Milos Judas, Masaharu Hayashi, Nenad Sesta. Selective depletion of molecularly defined cortical interneurons in human holoprosencephaly with severe striatal hypoplasia. Cerebral cortex (New York, N.Y. : 1991). vol 19. issue 9. 2009-10-21. PMID:19234067. |
however, whether molecularly defined human cortical interneuron subtypes originate from distinct progenitors, including those in the ventral forebrain, remains unknown. |
2009-10-21 |
2023-08-12 |
human |
| Eiman Azim, Denis Jabaudon, Ryann M Fame, Jeffrey D Mackli. SOX6 controls dorsal progenitor identity and interneuron diversity during neocortical development. Nature neuroscience. vol 12. issue 10. 2009-10-13. PMID:19657336. |
we found that the transcription factor sox6 controls the molecular segregation of dorsal (pallial) from ventral (subpallial) telencephalic progenitors and the differentiation of cortical interneurons, regulating forebrain progenitor and interneuron heterogeneity. |
2009-10-13 |
2023-08-12 |
mouse |
| Guoxin Ying, Sen Wu, Ruiqing Hou, Wei Huang, Mario R Capecchi, Qiang W. The protocadherin gene Celsr3 is required for interneuron migration in the mouse forebrain. Molecular and cellular biology. vol 29. issue 11. 2009-06-05. PMID:19332558. |
the protocadherin gene celsr3 is required for interneuron migration in the mouse forebrain. |
2009-06-05 |
2023-08-12 |
mouse |
| Guoxin Ying, Sen Wu, Ruiqing Hou, Wei Huang, Mario R Capecchi, Qiang W. The protocadherin gene Celsr3 is required for interneuron migration in the mouse forebrain. Molecular and cellular biology. vol 29. issue 11. 2009-06-05. PMID:19332558. |
we show that celsr3 is crucial for interneuron migration in the developing mouse forebrain. |
2009-06-05 |
2023-08-12 |
mouse |