| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Wiessner, I Brink, P Lorenz, T Neumann-Haefelin, P Vogel, K Yamashit. Cyclin D1 messenger RNA is induced in microglia rather than neurons following transient forebrain ischaemia. Neuroscience. vol 72. issue 4. 1996-11-01. PMID:8735222. |
since cyclin d1 codes for a critical regulatory protein for progression of the g0 to g1 phase in the cell cycle and we did not observe prominent occurrence of dna fragmentation in microglial cells in the hippocampus at time points when cyclin d1 messenger rna was found, we suggest that cyclin d1 induction is involved in the onset of microglial cell proliferation. |
1996-11-01 |
2023-08-12 |
rat |
| M J McCann, J P O'Callaghan, P M Martin, T Bertram, W J Strei. Differential activation of microglia and astrocytes following trimethyl tin-induced neurodegeneration. Neuroscience. vol 72. issue 1. 1996-10-24. PMID:8730724. |
we have investigated the response of astrocytes and microglia to trimethyl tin intoxication in the septum, hippocampus, olfactory bulb, and pyriform cortex of the rat. |
1996-10-24 |
2023-08-12 |
rat |
| M J McCann, J P O'Callaghan, P M Martin, T Bertram, W J Strei. Differential activation of microglia and astrocytes following trimethyl tin-induced neurodegeneration. Neuroscience. vol 72. issue 1. 1996-10-24. PMID:8730724. |
our results show that activated microglia first appeared 2 days after trimethyl tin intoxication in the lateral septum and hippocampus. |
1996-10-24 |
2023-08-12 |
rat |
| E K Speliotes, N W Kowall, B F Shanti, B Kosofsky, S P Finklestein, D Leife. Myocyte-specific enhancer binding factor 2C expression in gerbil brain following global cerebral ischemia. Neuroscience. vol 70. issue 1. 1996-10-24. PMID:8848137. |
mef2c-immunoreactivity was also detected in microglia in the hippocampus. |
1996-10-24 |
2023-08-12 |
Not clear |
| B Gajkowska, M J Mossakowsk. Localization of endothelin in the blood-brain interphase in rat hippocampus after global cerebral ischemia. Folia neuropathologica. vol 33. issue 4. 1996-08-12. PMID:8673430. |
endothelin-like immunoreactivity was found in endothelial cells of hippocampal microvessels and in astrocytes, microglia, macrophages and in some axonal endings. |
1996-08-12 |
2023-08-12 |
rat |
| M Mori, M Aihara, K Kume, M Hamanoue, S Kohsaka, T Shimiz. Predominant expression of platelet-activating factor receptor in the rat brain microglia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 11. 1996-07-12. PMID:8642404. |
cellular localization of platelet-activating factor (paf) receptor in the rat brain was determined by (1) in situ hybridization, (2) northern blot analysis in primary cell cultures of neurons, microglia, astrocytes, and fibroblasts, and (3) ca2+ imaging in hippocampal culture. |
1996-07-12 |
2023-08-12 |
rat |
| M Mori, M Aihara, K Kume, M Hamanoue, S Kohsaka, T Shimiz. Predominant expression of platelet-activating factor receptor in the rat brain microglia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 11. 1996-07-12. PMID:8642404. |
in primary hippocampal cultures, paf elevated intracellular ca2+ concentration in microglia and also in neurons, but to a lesser extent. |
1996-07-12 |
2023-08-12 |
rat |
| G Guinto, I Felix, A Riva. [A case of rabies encephalitis with long survival. Clinical pathological correlations]. Gaceta medica de Mexico. vol 131. issue 2. 1996-02-20. PMID:8549911. |
this case had the following important features; 1--a long time with the disease: usually the patients die into the first eight days after diagnosis; 2--the evident reactive gliosis; 3--almost all the studied fields showed inclusion bodies in both supratentorial and infratentorial portions; 4--the hippocampus and spinal cord neurons had many or unique negri bodies and some of those were giant; 5--microglia proliferation and free acidophilus bodies. |
1996-02-20 |
2023-08-12 |
Not clear |
| S E Tsirka, A Gualandris, D G Amaral, S Stricklan. Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator. Nature. vol 377. issue 6547. 1995-11-06. PMID:7566088. |
here we show that tpa is produced primarily by microglia in the hippocampus. |
1995-11-06 |
2023-08-12 |
mouse |
| T G Beach, W B Woodhurst, D B MacDonald, M W Jone. Reactive microglia in hippocampal sclerosis associated with human temporal lobe epilepsy. Neuroscience letters. vol 191. issue 1-2. 1995-09-29. PMID:7659283. |
reactive microglia in hippocampal sclerosis associated with human temporal lobe epilepsy. |
1995-09-29 |
2023-08-12 |
human |
| T G Beach, W B Woodhurst, D B MacDonald, M W Jone. Reactive microglia in hippocampal sclerosis associated with human temporal lobe epilepsy. Neuroscience letters. vol 191. issue 1-2. 1995-09-29. PMID:7659283. |
hla-dr-immunoreactive microglia were increased approximately 11-fold in ca1 and 3-fold in ca3, compared to control autopsy hippocampus. |
1995-09-29 |
2023-08-12 |
human |
| W E Maier, H W Brown, H A Tilson, M I Luster, G J Harr. Trimethyltin increases interleukin (IL)-1 alpha, IL-6 and tumor necrosis factor alpha mRNA levels in rat hippocampus. Journal of neuroimmunology. vol 59. issue 1-2. 1995-08-03. PMID:7797621. |
the onset of pro-inflammatory cytokine mrna expression appears to be temporally associated with histological evidence of elevated microglia in the hippocampus. |
1995-08-03 |
2023-08-12 |
rat |
| N Aihara, J J Hall, L H Pitts, K Fukuda, L J Nobl. Altered immunoexpression of microglia and macrophages after mild head injury. Journal of neurotrauma. vol 12. issue 1. 1995-07-17. PMID:7783232. |
prominently stained microglia were detected in the thalamus, hippocampus, lateral and medial geniculate body, and the substantia nigra. |
1995-07-17 |
2023-08-12 |
rat |
| K M Guthrie, T Nguyen, C M Gal. Insulin-like growth factor-1 mRNA is increased in deafferented hippocampus: spatiotemporal correspondence of a trophic event with axon sprouting. The Journal of comparative neurology. vol 352. issue 1. 1995-05-17. PMID:7714238. |
these results demonstrate that reactive microglia within deafferented hippocampal laminae express igf-1 mrna just prior to and during the period of reactive axonal growth and suggest that igf-1 plays a role in directing the sprouting of spared afferents into these fields. |
1995-05-17 |
2023-08-12 |
rat |
| E Lehrmann, R Kiefer, B Finsen, N H Diemer, J Zimmer, H P Hartun. Cytokines in cerebral ischemia: expression of transforming growth factor beta-1 (TGF-beta 1) mRNA in the postischemic adult rat hippocampus. Experimental neurology. vol 131. issue 1. 1995-04-27. PMID:7895806. |
transient global cerebral ischemia induces selective neuronal degeneration in the adult rat hippocampus, which is both preceded and accompanied by activation of microglia and astrocytes. |
1995-04-27 |
2023-08-12 |
rat |
| J A Shaw, V H Perry, J Mellanb. MHC class II expression by microglia in tetanus toxin-induced experimental epilepsy in the rat. Neuropathology and applied neurobiology. vol 20. issue 4. 1995-02-02. PMID:7808590. |
in animals with seizures, microglia in hippocampus are found to be activated. |
1995-02-02 |
2023-08-12 |
rat |
| J A Shaw, V H Perry, J Mellanb. MHC class II expression by microglia in tetanus toxin-induced experimental epilepsy in the rat. Neuropathology and applied neurobiology. vol 20. issue 4. 1995-02-02. PMID:7808590. |
after the animals have recovered from the acute phase at 8 weeks, the mhc class ii expression has largely disappeared from the substantia nigra but mhc class ii-expressing microglia are found in the dorsal hippocampus of those rats with loss of cells from ca1. |
1995-02-02 |
2023-08-12 |
rat |
| A McRae, K A Rudolphi, P Schuber. Propentosylline depresses amyloid and Alzheimer's CSF microglial antigens after ischaemia. Neuroreport. vol 5. issue 10. 1994-11-10. PMID:7919163. |
daily post-treatment with ppf, started 24 h after ischaemia, depressed the immunostaining of activated microglia by ad-csf, ox18 and app in the hippocampus. |
1994-11-10 |
2023-08-12 |
Not clear |
| M R Del Bigio, L E Becke. Microglial aggregation in the dentate gyrus: a marker of mild hypoxic-ischaemic brain insult in human infants. Neuropathology and applied neurobiology. vol 20. issue 2. 1994-09-27. PMID:8072645. |
there are many reports in experimental animals indicating that microglia are activated in the dentate gyrus and hippocampus following hypoxic-ischaemic brain injury. |
1994-09-27 |
2023-08-12 |
human |
| H Akiyama, I Tooyama, H Kondo, K Ikeda, H Kimura, E G McGeer, P L McGee. Early response of brain resident microglia to kainic acid-induced hippocampal lesions. Brain research. vol 635. issue 1-2. 1994-06-09. PMID:8173962. |
early response of brain resident microglia to kainic acid-induced hippocampal lesions. |
1994-06-09 |
2023-08-12 |
rat |