| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yimin Huang, Baole Zhang, Hannah Haneke, Verena Haage, Malgorzata Lubas, Yang Yuan, Pengfei Xia, Edyta Motta, Cynthia Nanvuma, Omar Dzaye, Feng Hu, Helmut Kettenman. Glial cell line-derived neurotrophic factor increases matrix metallopeptidase 9 and 14 expression in microglia and promotes microglia-mediated glioma progression. Journal of neuroscience research. vol 99. issue 4. 2021-11-30. PMID:33404121. |
glial cell line-derived neurotrophic factor increases matrix metallopeptidase 9 and 14 expression in microglia and promotes microglia-mediated glioma progression. |
2021-11-30 |
2023-08-13 |
mouse |
| Nils Förster, Joshua Butke, Hagen Eike Keßel, Farina Bendt, Melanie Pahl, Lu Li, Xiaohui Fan, Ping-Chung Leung, Jördis Klose, Stefan Masjosthusmann, Ellen Fritsche, Axel Mosi. Reliable identification and quantification of neural cells in microscopic images of neurospheres. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2021-11-19. PMID:34747115. |
differentiating hnpcs migrate and differentiate into radial glia, neurons, astrocytes, and oligodendrocytes upon plating on a suitable extracellular matrix and thus model processes of early neural development. |
2021-11-19 |
2023-08-13 |
human |
| D Kempuraj, R Thangavel, P A Natteru, G P Selvakumar, D Saeed, H Zahoor, S Zaheer, S S Iyer, A Zahee. Neuroinflammation Induces Neurodegeneration. Journal of neurology, neurosurgery and spine. vol 1. issue 1. 2021-11-16. PMID:28127589. |
neurodegeneration is mediated by inflammatory and neurotoxic mediators such as interleukin-1beta (il-1β), il-6, il-8, il-33, tumor necrosis factor-alpha (tnf-α), chemokine (c-c motif) ligand 2 (ccl2), ccl5, matrix metalloproteinase (mmps), granulocyte macrophage colony-stimulating factor (gm-csf), glia maturation factor (gmf), substance p, reactive oxygen species (ros), reactive nitrogen species (rns), mast cells-mediated histamine and proteases, protease activated receptor-2 (par-2), cd40, cd40l, cd88, intracellular ca |
2021-11-16 |
2023-08-13 |
Not clear |
| Elise C Cope, Anna D Zych, Nicole J Katchur, Renée C Waters, Blake J Laham, Emma J Diethorn, Christin Y Park, William R Meara, Elizabeth Goul. Atypical perineuronal nets in the CA2 region interfere with social memory in a mouse model of social dysfunction. Molecular psychiatry. 2021-11-09. PMID:34183768. |
we sought to identify potential mechanisms of social memory dysfunction in the hippocampus by investigating features of neurons, glia, and the extracellular matrix (ecm) of btbr mice, an inbred mouse strain with deficient social memory. |
2021-11-09 |
2023-08-13 |
mouse |
| Joshua D Crapser, Miguel A Arreola, Kate I Tsourmas, Kim N Gree. Microglia as hackers of the matrix: sculpting synapses and the extracellular space. Cellular & molecular immunology. vol 18. issue 11. 2021-10-31. PMID:34413489. |
instead, pre- and postsynaptic terminals are surrounded by extracellular matrix (ecm), which together with glia comprise the four elements of the contemporary tetrapartite synapse model. |
2021-10-31 |
2023-08-13 |
Not clear |
| Zinaida S Vexler, Xian Nan Tang, Midori A Yenar. Inflammation in adult and neonatal stroke. Clinical neuroscience research. vol 6. issue 5. 2021-10-20. PMID:20300490. |
it will review the role of specific cell types and interactions among blood cells, endothelium, glia, microglia, the extracellular matrix and neurons - cumulatively called "neurovascular unit" - in stroke induction and evolution. |
2021-10-20 |
2023-08-12 |
Not clear |
| Kevin Y Zhang, Thomas V Johnso. The internal limiting membrane: Roles in retinal development and implications for emerging ocular therapies. Experimental eye research. vol 206. 2021-09-13. PMID:33753089. |
here we take a neurodevelopmental perspective in examining how retinal neurons, glia, and vasculature interact with individual extracellular matrix constituents at the ilm. |
2021-09-13 |
2023-08-13 |
Not clear |
| Diede Wm Broekaart, Alexandra Bertran, Shaobo Jia, Anatoly Korotkov, Oleg Senkov, Anika Bongaarts, James D Mills, Jasper J Anink, Jesús Seco, Johannes C Baayen, Sander Idema, Elodie Chabrol, Albert J Becker, Wytse J Wadman, Teresa Tarragó, Jan A Gorter, Eleonora Aronica, Roger Prades, Alexander Dityatev, Erwin A van Vlie. The matrix metalloproteinase inhibitor IPR-179 has antiseizure and antiepileptogenic effects. The Journal of clinical investigation. vol 131. issue 1. 2021-09-07. PMID:33141761. |
matrix metalloproteinases (mmps) are synthesized by neurons and glia and released into the extracellular space, where they act as modulators of neuroplasticity and neuroinflammatory agents. |
2021-09-07 |
2023-08-13 |
mouse |
| Andrew H Hoover, Ratnamala Pavuluri, Gajanan P Shelkar, Shashank M Dravid, Yoland Smith, Rosa M Villalb. Ultrastructural localization of glutamate delta 1 (GluD1) receptor immunoreactivity in the mouse and monkey striatum. The Journal of comparative neurology. vol 529. issue 7. 2021-08-16. PMID:33084025. |
at the electron microscopic level, glud1-ir was preferentially expressed in dendritic shafts (47.9 ± 1.2%), followed by glia (37.7 ± 2.5%), and dendritic spines (14.3 ± 2.6%) in the matrix of the mouse striatum. |
2021-08-16 |
2023-08-13 |
mouse |
| Femke Mathot, Nadia Rbia, Roman Thaler, Allan B Dietz, Andre J van Wijnen, Allen T Bishop, Alexander Y Shi. Gene expression profiles of human adipose-derived mesenchymal stem cells dynamically seeded on clinically available processed nerve allografts and collagen nerve guides. Neural regeneration research. vol 16. issue 8. 2021-08-13. PMID:33433492. |
neurotrophic [nerve growth factor (ngf), glial cell line-derived neurotrophic factor (gdnf), pleiotrophin (ptn), growth associated protein 43 (gap43) and brain-derived neurotrophic factor (bdnf)], myelination [peripheral myelin protein 22 (pmp22) and myelin protein zero (mpz)], angiogenic [platelet endothelial cell adhesion molecule 1 (pecam1/cd31) and vascular endothelial cell growth factor alpha (vegfa)], extracellular matrix (ecm) [collagen type alpha i (col1a1), collagen type alpha iii (col3a1), fibulin 1 (fbln1) and laminin subunit beta 2 (lamb2)] and cell surface marker cluster of differentiation 96 (cd96) gene expression was quantified. |
2021-08-13 |
2023-08-13 |
human |
| Joao Pereira Leite, Jose Eduardo Peixoto-Santo. Glia and extracellular matrix molecules: What are their importance for the electrographic and MRI changes in the epileptogenic zone? Epilepsy & behavior : E&B. vol 121. issue Pt B. 2021-08-11. PMID:31884121. |
glia and extracellular matrix molecules: what are their importance for the electrographic and mri changes in the epileptogenic zone? |
2021-08-11 |
2023-08-13 |
Not clear |
| Claire Hippert, Anna B Graca, Mark Basche, Aikaterini A Kalargyrou, Anastasios Georgiadis, Joana Ribeiro, Ayako Matsuyama, Nozie Aghaizu, James W Bainbridge, Alexander J Smith, Robin R Ali, Rachael A Pearso. RNAi-mediated suppression of vimentin or glial fibrillary acidic protein prevents the establishment of Müller glial cell hypertrophy in progressive retinal degeneration. Glia. vol 69. issue 9. 2021-07-09. PMID:34029407. |
gliosis is a complex process comprising upregulation of intermediate filament (if) proteins, particularly glial fibrillary acidic protein (gfap) and vimentin, changes in glial cell morphology (hypertrophy) and increased deposition of inhibitory extracellular matrix molecules. |
2021-07-09 |
2023-08-13 |
Not clear |
| John G Cooper, Delphine Sicard, Sripadh Sharma, Stephanie Van Gulden, Tammy L McGuire, Miguel Pareja Cajiao, Daniel J Tschumperlin, John A Kessle. Spinal Cord Injury Results in Chronic Mechanical Stiffening. Journal of neurotrauma. vol 37. issue 3. 2021-06-11. PMID:31516087. |
the scar consists of a meshwork of reactive glia and deposited, cross-linked, extracellular matrix (ecm) that has long been assumed to present a mechanically "stiff" blockade. |
2021-06-11 |
2023-08-13 |
mouse |
| Scoty Hearst, Andrea Bednářová, Benjamin Draughn, Kennadi Johnson, Desiree Mills, Cendonia Thomas, Jendaya Scales, Eadie T Keenan, Jewellian V Welcher, Natraj Krishna. Expression of Drosophila Matrix Metalloproteinases in Cultured Cell Lines Alters Neural and Glial Cell Morphology. Frontiers in cell and developmental biology. vol 9. 2021-06-01. PMID:34055768. |
expression of drosophila matrix metalloproteinases in cultured cell lines alters neural and glial cell morphology. |
2021-06-01 |
2023-08-13 |
human |
| Agnieszka Łukomska, Irena Baranowska-Bosiacka, Karolina Dec, Anna Pilutin, Maciej Tarnowski, Karolina Jakubczyk, Wojciech Żwierełło, Marta Skórka-Majewicz, Dariusz Chlubek, Izabela Gutowsk. Changes in Gene and Protein Expression of Metalloproteinase-2 and -9 and Their Inhibitors TIMP2 and TIMP3 in Different Parts of Fluoride-Exposed Rat Brain. International journal of molecular sciences. vol 22. issue 1. 2021-04-02. PMID:33396569. |
these enzymes, especially matrix metalloproteinases (mmps) and their tissue inhibitors (timps), are involved in both physiological processes, such as learning or memory, and pathological processes like glia scare formation, brain tissue regeneration, brain-blood barrier damage and inflammation. |
2021-04-02 |
2023-08-13 |
rat |
| Xandra Pereiro, Roberto Fernández, Gabriel Barreda-Gómez, Noelia Ruzafa, Arantxa Acera, Javier Araiz, Egoitz Astigarraga, Elena Vecin. Comparative lipidomic analysis of mammalian retinal ganglion cells and Müller glia in situ and in vitro using High-Resolution Imaging Mass Spectrometry. Scientific reports. vol 10. issue 1. 2021-03-30. PMID:33208898. |
the lipidome of müller glia and rgcs was analyzed in porcine retinal sections using matrix assisted laser desorption ionization imaging mass spectrometry (maldi-ims). |
2021-03-30 |
2023-08-13 |
Not clear |
| Jie Hao, Corina Kohler, Hubrecht van den Dorpel, Hendrik P N Scholl, Peter Meyer, Hanspeter E Killer, Albert Neutzne. The extracellular matrix composition of the optic nerve subarachnoid space. Experimental eye research. vol 200. 2021-03-02. PMID:32956686. |
meningeal-derived extracellular matrix (ecm) is a crucial component of the pial basement membrane, glia limitans and important for maintenance of optic nerve axon integrity, homeostasis and retinal ganglion cell health. |
2021-03-02 |
2023-08-13 |
human |
| Ciro De Luca, Anna Maria Colangelo, Assunta Virtuoso, Lilia Alberghina, Michele Pap. Neurons, Glia, Extracellular Matrix and Neurovascular Unit: A Systems Biology Approach to the Complexity of Synaptic Plasticity in Health and Disease. International journal of molecular sciences. vol 21. issue 4. 2020-11-23. PMID:32102370. |
neurons, glia, extracellular matrix and neurovascular unit: a systems biology approach to the complexity of synaptic plasticity in health and disease. |
2020-11-23 |
2023-08-13 |
Not clear |
| Ciro De Luca, Anna Maria Colangelo, Assunta Virtuoso, Lilia Alberghina, Michele Pap. Neurons, Glia, Extracellular Matrix and Neurovascular Unit: A Systems Biology Approach to the Complexity of Synaptic Plasticity in Health and Disease. International journal of molecular sciences. vol 21. issue 4. 2020-11-23. PMID:32102370. |
moreover, synaptic plasticity and its pathological counterpart (maladaptive plasticity) have shown a deep connection with other molecular elements of the extracellular matrix (ecm), once considered as a mere extracellular structural scaffold altogether with the cellular glue (i.e., glia). |
2020-11-23 |
2023-08-13 |
Not clear |
| Dominik Michalski, Emma Spielvogel, Joana Puchta, Willi Reimann, Henryk Barthel, Björn Nitzsche, Bianca Mages, Carsten Jäger, Henrik Martens, Anja K E Horn, Stefan Schob, Wolfgang Härti. Increased Immunosignals of Collagen IV and Fibronectin Indicate Ischemic Consequences for the Neurovascular Matrix Adhesion Zone in Various Animal Models and Human Stroke Tissue. Frontiers in physiology. vol 11. 2020-11-17. PMID:33192578. |
ischemic stroke causes cellular alterations in the "neurovascular unit" (nvu) comprising neurons, glia, and the vasculature, and affects the blood-brain barrier (bbb) with adjacent extracellular matrix (ecm). |
2020-11-17 |
2023-08-13 |
mouse |