| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniela M Roth, Jeremie Oliver Piña, Melissa MacPherson, Curtis Budden, Daniel Gra. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association. 2023-06-05. PMID:37271984. |
the authors herein present four syndromes, selected from a literature review, and their identified biological mechanisms in the context of altered suture physiology, exploring the roles of progenitor cell differentiation, extracellular matrix production, mineralization, and bone resorption. |
2023-06-05 |
2023-08-14 |
Not clear |
| Yang Liu, Manoj Puthia, Eamon J Sheehy, Ines Ambite, Jikta Petrlova, Sujeethkumar Prithviraj, Maria Wimer Oxborg, Sujeesh Sebastian, Corina Vater, Stefan Zwingenberger, André Struglics, Paul E Bourgine, Fergal J O'Brien, Deepak Bushan Rain. Sustained Delivery of a Heterodimer Bone Morphogenetic Protein-2/7 via a Collagen Hydroxyapatite Scaffold Accelerates and Improves Critical Femoral Defect Healing. Acta biomaterialia. 2023-03-26. PMID:36967054. |
further evaluation of the molecular mechanisms responsible for this increased osteoinductivity at an early stage in the regeneration process indicated that the cha+bmp-2/7 enhanced progenitor cell homing at the implantation site, upregulated the key transcriptomic determinants of bone formation, and increased the production of bone extracellular matrix components. |
2023-03-26 |
2023-08-14 |
rat |
| Joshua S Godwin, Casey L Sexton, Nicholas J Kontos, Bradley A Ruple, Darryn S Willoughby, Kaelin C Young, C Brooks Mobley, Michael D Robert. Extracellular matrix content and remodeling markers do not differ in college-aged men classified as higher- and lower-responders to resistance training. Journal of applied physiology (Bethesda, Md. : 1985). 2023-02-09. PMID:36759158. |
in all participants, training reduced matrix metalloprotease (mmp)-14 protein (p<0.001) and increased satellite cell abundance (p<0.001); however, vl fascial thickness, ecm protein content per myofiber, mmp-2/-9 protein content, tissue inhibitor of metalloproteinase (timp)-1/-2 protein content, collagen-1/-4 protein content, macrophage abundance, or fibro-adipogenic progenitor cell abundance were not altered. |
2023-02-09 |
2023-08-14 |
human |
| Cynthia M Co, Tam Nguyen, Bhavya Vaish, Samira Izuagbe, Joseph Borrelli, Liping Tan. Biomolecule-releasing Bioadhesive for Glenoid Labrum Repair Through Induced Host Progenitor Cell Responses. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2022-11-30. PMID:36448179. |
after 3 and 6 weeks, the labrum was histologically analyzed for inflammatory responses, progenitor cell recruitment, proliferation, and extracellular matrix (ecm) production (collagen and glycosaminoglycan). |
2022-11-30 |
2023-08-14 |
human |
| Wisarut Kiratitanaporn, David B Berry, Anusorn Mudla, Trevor Fried, Alison Lao, Claire Yu, Nan Hao, Samuel R Ward, Shaochen Che. 3D printing a biocompatible elastomer for modeling muscle regeneration after volumetric muscle loss. Biomaterials advances. vol 142. 2022-11-07. PMID:36341746. |
the effect of both geometric (channel sizes between 300 and 600 μm) and biologic (decellularized muscle extracellular matrix (decm)) cues on muscle progenitor cell infiltration, proliferation, organization, and maturation was evaluated in vitro using a near-infrared fluorescent protein (irfp) transfected cell line to assess cells in the 3d scaffold. |
2022-11-07 |
2023-08-14 |
Not clear |
| Elizabeth R Sharlow, Danielle C Llaneza, William E Grever, Garnett A Mingledorff, Anna J Mendelson, George S Bloom, John S Laz. High content screening miniaturization and single cell imaging of mature human feeder layer-free iPSC-derived neurons. SLAS discovery : advancing life sciences R & D. 2022-10-23. PMID:36273809. |
using our defined extracellular matrix and low oxygen culturing conditions for the differentiation and maturation of human cortical neurons, we further modified neuronal progenitor cell seeding densities and feeder layer-free culturing conditions in miniaturized formats (i.e., 96 well) to decrease neuronal clustering, enhance single-cell identification and reduce edge effects usually observed after extended neuronal cell culture. |
2022-10-23 |
2023-08-14 |
human |
| James Melros. Fractone Stem Cell Niche Components Provide Intuitive Clues in the Design of New Therapeutic Procedures/Biomatrices for Neural Repair. International journal of molecular sciences. vol 23. issue 9. 2022-05-14. PMID:35563536. |
the extracellular matrix associated with the fractone stem cell niche contains hyaluronan, perlecan and laminin α5, which regulate the quiescent recycling of stem cells and also provide a means of escaping to undergo the proliferation and differentiation to a pluripotent migratory progenitor cell type that can participate in repair processes in neural tissues. |
2022-05-14 |
2023-08-13 |
Not clear |
| Anna Karen Sigurdardottir, Bylgja Hilmarsdottir, Thorarinn Gudjonsson, Gunnhildur Asta Traustadotti. Application of 3D Culture Assays to Study Breast Morphogenesis, Epithelial Plasticity, and Cellular Interactions in an Epithelial Progenitor Cell Line. Methods in molecular biology (Clifton, N.J.). vol 2429. 2022-05-04. PMID:35507176. |
d492 is a breast epithelial progenitor cell line that provides a model for branching morphogenesis when cultured in 3d reconstituted basement membrane matrix (rbm). |
2022-05-04 |
2023-08-13 |
Not clear |
| Alejandro Martinez Chibly, Marit H Aure, Vaishali N Patel, Matthew Philip Hoffma. Salivary Gland Function, Development and Regeneration. Physiological reviews. 2022-03-28. PMID:35343828. |
significant recent advances, particularly in the omics field, increase our understanding of how salivary glands develop at the cellular, molecular and genetic levels; the signaling pathways involved, the dynamics of progenitor cell lineages in development, homeostasis and regeneration and the role of the extracellular matrix microenvironment. |
2022-03-28 |
2023-08-13 |
Not clear |
| Qi Zhou, Shengyu Lyu, Anthony A Bertrand, Allison C Hu, Candace H Chan, Xiaoyan Ren, Marley J Dewey, Aleczandria S Tiffany, Brendan A C Harley, Justine C Le. Stiffness of Nanoparticulate Mineralized Collagen Scaffolds Triggers Osteogenesis via Mechanotransduction and Canonical Wnt Signaling. Macromolecular bioscience. vol 21. issue 3. 2021-11-11. PMID:33382197. |
the ability of the extracellular matrix (ecm) to instruct progenitor cell differentiation has generated excitement for the development of materials-based regenerative solutions. |
2021-11-11 |
2023-08-13 |
human |
| Yiming Liu, Li Ding, Bowen Zhang, Ziliang Deng, Yi Han, Sihan Wang, Shu Yang, Zeng Fan, Jing Zhang, Hongmin Yan, Dongmei Han, Lijuan He, Wen Yue, Hengxiang Wang, Yanhua Li, Xuetao Pe. Thrombopoietin enhances hematopoietic stem and progenitor cell homing by impeding matrix metalloproteinase 9 expression. Stem cells translational medicine. vol 9. issue 6. 2021-07-01. PMID:32125099. |
thrombopoietin enhances hematopoietic stem and progenitor cell homing by impeding matrix metalloproteinase 9 expression. |
2021-07-01 |
2023-08-13 |
mouse |
| Eric J Marrotte, Khari Johnson, Ryan M Schweller, Rachel Chapla, Brian E Mace, Daniel T Laskowitz, Jennifer L Wes. Induction of Neurogenesis and Angiogenesis in a Rat Hemisection Spinal Cord Injury Model With Combined Neural Stem Cell, Endothelial Progenitor Cell, and Biomimetic Hydrogel Matrix Therapy. Critical care explorations. vol 3. issue 6. 2021-06-26. PMID:34151277. |
induction of neurogenesis and angiogenesis in a rat hemisection spinal cord injury model with combined neural stem cell, endothelial progenitor cell, and biomimetic hydrogel matrix therapy. |
2021-06-26 |
2023-08-13 |
rat |
| Dheraj K Taheem, Gavin Jell, Eileen Gentlema. Hypoxia Inducible Factor-1α in Osteochondral Tissue Engineering. Tissue engineering. Part B, Reviews. vol 26. issue 2. 2021-06-04. PMID:31774026. |
the cellular response to these spatial variations in oxygen pressure, which is mediated by the hypoxia inducible factor (hif) pathway, plays a central role in regulating osteo- and chondrogenesis by directing progenitor cell differentiation and promoting and maintaining appropriate extracellular matrix production. |
2021-06-04 |
2023-08-13 |
Not clear |
| Deniz B Unal, Steven R Caliari, Kyle J Lamp. 3D Hyaluronic Acid Hydrogels for Modeling Oligodendrocyte Progenitor Cell Behavior as a Function of Matrix Stiffness. Biomacromolecules. vol 21. issue 12. 2021-05-24. PMID:33112592. |
3d hyaluronic acid hydrogels for modeling oligodendrocyte progenitor cell behavior as a function of matrix stiffness. |
2021-05-24 |
2023-08-13 |
Not clear |
| Leslie Frapin, Johann Clouet, Claire Chédeville, Constantin Moraru, Edouard Samarut, Nina Henry, Manon André, Eric Bord, Boris Halgand, Julie Lesoeur, Marion Fusellier, Jérôme Guicheux, Catherine Le Visag. Controlled release of biological factors for endogenous progenitor cell migration and intervertebral disc extracellular matrix remodelling. Biomaterials. vol 253. 2021-05-14. PMID:32450408. |
controlled release of biological factors for endogenous progenitor cell migration and intervertebral disc extracellular matrix remodelling. |
2021-05-14 |
2023-08-13 |
human |
| Tobias M Ballhause, Shan Jiang, Anke Baranowsky, Sabine Brandt, Peter R Mertens, Karl-Heinz Frosch, Timur Yorgan, Johannes Kelle. Relevance of Notch Signaling for Bone Metabolism and Regeneration. International journal of molecular sciences. vol 22. issue 3. 2021-04-16. PMID:33572704. |
numerous functions have been assigned to notch receptors and ligands, including osteoblast differentiation and matrix mineralization, osteoclast recruitment and cell fusion and osteoblast/osteoclast progenitor cell proliferation. |
2021-04-16 |
2023-08-13 |
Not clear |
| Mark C Daley, Mattia Bonzanni, Allison M MacKenzie, David L Kaplan, Lauren D Blac. The effects of membrane potential and extracellular matrix composition on vascular differentiation of cardiac progenitor cells. Biochemical and biophysical research communications. vol 530. issue 1. 2021-02-26. PMID:32828293. |
we examine how cardiac progenitor cell differentiation is altered by simultaneous changes in both resting membrane potential and extracellular matrix composition. |
2021-02-26 |
2023-08-13 |
Not clear |
| Eve Helena Rogers, Vanja Pekovic-Vaughan, John Alan Hun. Mechanical stretch and chronotherapeutic techniques for progenitor cell transplantation and biomaterials. BioMedicine. vol 8. issue 3. 2021-01-09. PMID:30141401. |
tensile stress, or compression loading are just two of these forces, and here we examine the role of cyclical or dynamic mechanical loading on progenitor cell proliferation and differentiation, as well as on other cellular processes including cell morphology, apoptosis and matrix mineralisation. |
2021-01-09 |
2023-08-13 |
human |
| Francisca M Acosta, U-Ter Aonda Jia, Katerina Stojkova, Settimio Pacelli, Eric M Brey, Christopher Rathbon. Divergent effects of myogenic differentiation and diabetes on the capacity for muscle precursor cell adipogenic differentiation in a fibrin matrix. Biochemical and biophysical research communications. vol 526. issue 1. 2020-11-24. PMID:32192775. |
divergent effects of myogenic differentiation and diabetes on the capacity for muscle precursor cell adipogenic differentiation in a fibrin matrix. |
2020-11-24 |
2023-08-13 |
rat |
| Yukiko Sugi, Michael J Kern, Roger R Markwald, Jessica L Burnsid. Periostin Expression is Altered in Aortic Valves in Smad6 Mutant Mice. Journal of neonatal biology. vol 1. 2020-10-01. PMID:25383261. |
periostin is a 90-kda secreted extracellular matrix (ecm) protein and implicated in cardiac valve progenitor cell differentiation, maturation and adult aortic valve calcification in mice. |
2020-10-01 |
2023-08-13 |
mouse |