| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Seico Benner, Toshihiro Endo, Nozomi Endo, Masaki Kakeyama, Chiharu Tohyam. Early deprivation induces competitive subordinance in C57BL/6 male mice. Physiology & behavior. vol 137. 2015-06-16. PMID:25089814. |
analyzing gene expression changes in brain regions controlling emotion, stress, spatial memory, and executive function revealed reduced bdnf and c-fos in hippocampal ca1, enhanced c-fos in the basolateral amygdala, reduced map2 while enhanced hsd11β2 in prefrontal cortex of ed males. |
2015-06-16 |
2023-08-13 |
mouse |
| F Fernandez-Enright, J L Andrews, K A Newell, C Pantelis, X F Huan. Novel implications of Lingo-1 and its signaling partners in schizophrenia. Translational psychiatry. vol 4. 2015-03-06. PMID:24448210. |
we examined protein levels of lingo-1, ngr, troy, p75, wnk1, myt1 and myelin basic protein (mbp) (as a marker of myelination) within the post-mortem dorsolateral prefrontal cortex (dlpfc) (37 schizophrenia patients versus 37 matched controls) and hippocampus (cornu ammonis, ca1 and ca3) (20 schizophrenia patients versus 20 matched controls from the same cohort). |
2015-03-06 |
2023-08-12 |
human |
| M Kiray, A R Sisman, U M Camsari, M Evren, A Dayi, B Baykara, I Aksu, M Ates, Nazan Uysa. Effects of carbon dioxide exposure on early brain development in rats. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 89. issue 5. 2015-02-23. PMID:24476563. |
in addition, apoptosis was increased, while cell numbers were decreased in the ca1 regions of hippocampus and pfc after 0.3% co2 air exposure in adolescent rats. |
2015-02-23 |
2023-08-12 |
rat |
| Israel Camacho-Abrego, Gullermina Tellez-Merlo, Angel I Melo, Antonio Rodríguez-Moreno, Linda Garcés, Fidel De La Cruz, Sergio Zamudio, Gonzalo Flore. Rearrangement of the dendritic morphology of the neurons from prefrontal cortex and hippocampus after subthalamic lesion in Sprague-Dawley rats. Synapse (New York, N.Y.). vol 68. issue 3. 2014-09-23. PMID:24265191. |
we found that stn damage induced a deficit in locomotion measured by open field test with neuronal hypertrophy in pfc (layer 5) and reduced spinogenesis in ca1 ventral hippocampus and pfc (layer 3). |
2014-09-23 |
2023-08-12 |
rat |
| Bill P Godsil, Janos P Kiss, Michael Spedding, Thérèse M Ja. The hippocampal-prefrontal pathway: the weak link in psychiatric disorders? European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 10. 2014-04-24. PMID:23332457. |
recent research in rodents compellingly supports the idea that the projection of neurons extending from the ca1 region of the hippocampus and from the subiculum to the prefrontal cortex, referred to here as the h-pfc pathway, is critically involved in aspects of cognition related to executive function and to emotional regulation. |
2014-04-24 |
2023-08-12 |
Not clear |
| Anna S Karlsen, Sanne S Kaalund, Morten Møller, Niels Plath, Bente Pakkenber. Expression of presynaptic markers in a neurodevelopmental animal model with relevance to schizophrenia. Neuroreport. vol 24. issue 16. 2014-04-16. PMID:24045778. |
using radioactive in-situ hybridization, the expression of snap25 was measured in the prefrontal cortex and the hippocampal formation (ca1, ca3, ca4, and dentate gyrus) at pnd 29 and 80 in neopcp and control rats. |
2014-04-16 |
2023-08-12 |
rat |
| José R Santos, João A S Cunha, Aline L Dierschnabel, Clarissa L C Campêlo, Anderson H F F Leão, Anatildes F Silva, Rovena C G J Engelberth, Geison S Izídio, Jeferson S Cavalcante, Vanessa C Abílio, Alessandra M Ribeiro, Regina H Silv. Cognitive, motor and tyrosine hydroxylase temporal impairment in a model of parkinsonism induced by reserpine. Behavioural brain research. vol 253. 2014-03-18. PMID:23831411. |
furthermore, the motor alterations were statistically correlated with decreased th levels (gd, ca1, pfc and ds) and number of th+ cells (snpc and vta) in the brain. |
2014-03-18 |
2023-08-12 |
rat |
| Kazuko Sakata, Keri Martinowich, Newton H Woo, Robert J Schloesser, Dennisse V Jimenez, Yuanyuan Ji, Liya Shen, Bai L. Role of activity-dependent BDNF expression in hippocampal-prefrontal cortical regulation of behavioral perseverance. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 37. 2013-12-10. PMID:23980178. |
here, we show that disruption of activity-dependent bdnf expression impairs bdnf-dependent late-phase long-term potentiation (l-ltp) in ca1, a site of hippocampal output to the pfc. |
2013-12-10 |
2023-08-12 |
mouse |
| Samuel G Ewing, Christine Winte. The ventral portion of the CA1 region of the hippocampus and the prefrontal cortex as candidate regions for neuromodulation in schizophrenia. Medical hypotheses. vol 80. issue 6. 2013-12-02. PMID:23583328. |
the ventral portion of the ca1 region of the hippocampus and the prefrontal cortex as candidate regions for neuromodulation in schizophrenia. |
2013-12-02 |
2023-08-12 |
Not clear |
| Hiroshi Ueno, Chikafumi Shoshi, Shunsuke Suemitsu, Shinichi Usui, Hiroko Sujiura, Motoi Okamot. Somatosensory and visual deprivation each decrease the density of parvalbumin neurons and their synapse terminals in the prefrontal cortex and hippocampus of mice. Acta medica Okayama. vol 67. issue 3. 2013-10-22. PMID:23804136. |
dark rearing decreased the density of gad67-positive puncta in ca1 of the hippocampus and in both l2/3 and l5/6 of the prefrontal cortex at p28, and in l2/3 of the prefrontal cortex at p56. |
2013-10-22 |
2023-08-12 |
mouse |
| T Kiss, J Feng, W E Hoffmann, C L Shaffer, M Hajó. Rhythmic theta and delta activity of cortical and hippocampal neuronal networks in genetically or pharmacologically induced N-methyl-D-aspartate receptor hypofunction under urethane anesthesia. Neuroscience. vol 237. 2013-09-23. PMID:23396086. |
field potentials were recorded from the ventro-medial prefrontal cortex (mpfc) and hippocampus (ca1) in rats, as well as spontaneous and elicited hippocampal theta oscillations in response to brainstem stimulation in grin1 and wild-type (wt) mice under anesthesia. |
2013-09-23 |
2023-08-12 |
mouse |
| Kazım Tugyan, Seda Ozbal, Serap Cilaker, Muge Kiray, Cetin Pekcetin, Bekir Ugur Ergur, Abdullah Kumra. Neuroprotective effect of erythropoietin on nandrolone decanoate-induced brain injury in rats. Neuroscience letters. vol 533. 2013-05-23. PMID:23063952. |
the number of neurons of ca1, ca2, ca3 and dentate gyrus of hippocampus, parietal cortex and prefrontal cortex were significantly less in the nd group compared with the control group. |
2013-05-23 |
2023-08-12 |
rat |
| M E Torres-García, O Solis, A Patricio, A Rodríguez-Moreno, I Camacho-Abrego, I D Limón, G Flore. Dendritic morphology changes in neurons from the prefrontal cortex, hippocampus and nucleus accumbens in rats after lesion of the thalamic reticular nucleus. Neuroscience. vol 223. 2013-05-01. PMID:22858596. |
we found that trn damage induced a reduction in the exploratory behavior measured by hole-board test with neuronal hypotrophy in pfc (layer 5), ca1 ventral hippocampus and nacc neurons. |
2013-05-01 |
2023-08-12 |
rat |
| Guang-Biao Huang, Tong Zhao, Chun-Rong Li, Zhi-Yan Sui, Nam-In Kang, Eui-Hyeog Han, Young-Chul Chun. Choline acetyltransferase expression in rat prefrontal cortex and hippocampus after acute and chronic exposure to amisulpride, haloperidol, and risperidone. Neuroscience letters. vol 528. issue 2. 2012-12-20. PMID:22999925. |
target areas of brain were pfc and hip (ca1, ca3 and dg). |
2012-12-20 |
2023-08-12 |
rat |
| John P Aggleto. Multiple anatomical systems embedded within the primate medial temporal lobe: implications for hippocampal function. Neuroscience and biobehavioral reviews. vol 36. issue 7. 2012-12-19. PMID:21964564. |
these efferent systems and their putative memory functions are: (1) the 'extended-hippocampal system' for episodic memory, which involves the anterior thalamic nuclei, mammillary bodies and retrosplenial cortex, originates in the subicular cortices, and has a largely laminar organisation; (2) the 'rostral hippocampal system' for affective and social learning, which involves prefrontal cortex, amygdala and nucleus accumbens, has a columnar organisation, and originates from rostral ca1 and subiculum; (3) the 'reciprocal hippocampal-parahippocampal system' for sensory processing and integration, which originates from the length of ca1 and the subiculum, and is characterised by columnar, connections with reciprocal topographies. |
2012-12-19 |
2023-08-12 |
Not clear |
| V B Thompson, J B Koprich, E Y Chen, J H Kordower, B T Terpstra, J W Lipto. Prenatal exposure to MDMA alters noradrenergic neurodevelopment in the rat. Neurotoxicology and teratology. vol 34. issue 1. 2012-10-15. PMID:21978916. |
offspring that were prenatally exposed to mdma exhibited an increase in noradrenergic fiber density in the prelimbic region of the prefrontal cortex and the ca1 region of the hippocampus that was not accompanied by an increase in the number of noradrenergic neurons in the locus coeruleus. |
2012-10-15 |
2023-08-12 |
rat |
| Logan T Knox, Yu Jing, Michael S Fleete, Nicola D Collie, Hu Zhang, Ping Li. Scopolamine impairs behavioural function and arginine metabolism in the rat dentate gyrus. Neuropharmacology. vol 61. issue 8. 2012-08-01. PMID:21903106. |
after completion of the behavioural testing, the ca1, ca2/3 and dentate gyrus (dg) sub-regions of the hippocampus and the prefrontal cortex were harvested to measure the activity and protein expression of nitric oxide synthase (nos) and arginase, and the levels of l-arginine, l-citrulline, l-ornithine, agmatine, putrescine, spermidine, spermine, glutamate and gaba. |
2012-08-01 |
2023-08-12 |
rat |
| Konstantinos Sarantis, Katerina Antoniou, Nikolaos Matsokis, Fevronia Angelato. Exposure to novel environment is characterized by an interaction of D1/NMDA receptors underlined by phosphorylation of the NMDA and AMPA receptor subunits and activation of ERK1/2 signaling, leading to epigenetic changes and gene expression in rat hippocampus. Neurochemistry international. vol 60. issue 1. 2012-06-20. PMID:22080157. |
our results showed that the "spatial" novelty induced in rat hippocampus and pfc (a) a significant increase in phosphorylation of nmda and ampa receptor subunits, as well as a robust phosphorylation/activation of erk1/2 signaling, which are both dependent on the concomitant stimulation of d1/nmda receptors and are both abolished by habituation procedure, (b) chromatin remodeling events (phosphorylation-acetylation of histone h3) and (c) an increase in the immediate early genes (iegs) c-fos and zif-268 expression in the ca1 region of hippocampus, which is dependent on the co-activation of d1/nmda and acetylcholine muscarinic receptors. |
2012-06-20 |
2023-08-12 |
rat |
| Ismael Juárez, Deniss Janeth González, Raúl Mena, Gonzalo Flore. The chronic administration of cerebrolysin induces plastic changes in the prefrontal cortex and dentate gyrus in aged mice. Synapse (New York, N.Y.). vol 65. issue 11. 2012-06-18. PMID:21544867. |
here we evaluated the effect of this drug on the dendrites of pyramidal neurons of the pfc and ca1 dorsal hippocampus and granule cells from the dentate gyrus (dg) and medium spiny neurons of the nucleus accumbens (nacc) of aged mice. |
2012-06-18 |
2023-08-12 |
mouse |
| Richelle Mychasiuk, Robbin Gibb, Bryan Kol. Prenatal bystander stress induces neuroanatomical changes in the prefrontal cortex and hippocampus of developing rat offspring. Brain research. vol 1412. 2012-02-21. PMID:21816391. |
dendritic architecture (dendritic length, branch order, and spine density) along with cell quantification (neuron and glia) was generated for layer 3 pyramidal cells of the medial prefrontal cortex (mpfc/cg3), orbital prefrontal cortex (ofc/aid), and ca1 of the hippocampus. |
2012-02-21 |
2023-08-12 |
rat |