| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christy M Kelley, Sylvia E Perez, Elliott J Mufso. Tau pathology in the medial temporal lobe of athletes with chronic traumatic encephalopathy: a chronic effects of neurotrauma consortium study. Acta neuropathologica communications. vol 7. issue 1. 2020-09-25. PMID:31831066. |
the medial temporal lobe (mtl; i.e., hippocampus, subiculum, and entorhinal and perirhinal cortices) memory circuit displays tau lesions during the pathological progression of cte. |
2020-09-25 |
2023-08-13 |
Not clear |
| Gustavo A Rodriguez, Geoffrey M Barrett, Karen E Duff, S Abid Hussain. Chemogenetic attenuation of neuronal activity in the entorhinal cortex reduces Aβ and tau pathology in the hippocampus. PLoS biology. vol 18. issue 8. 2020-09-17. PMID:32822389. |
using a novel transgenic mouse line to model the impact of human app (happ)/aβ accumulation on tauopathy in the entorhinal cortex-hippocampal (ec-hipp) network, we demonstrate that happ overexpression aggravates ec-tau aggregation and accelerates pathological tau spread into the hippocampus. |
2020-09-17 |
2023-08-13 |
mouse |
| Christopher D Morrone, Paolo Bazzigaluppi, Tina L Beckett, Mary E Hill, Margaret M Koletar, Bojana Stefanovic, JoAnne McLauri. Regional differences in Alzheimer's disease pathology confound behavioural rescue after amyloid-β attenuation. Brain : a journal of neurology. vol 143. issue 1. 2020-08-18. PMID:31782760. |
reduction of amyloid-β peptide in the entorhinal cortex had no effect on entorhinal tau pathology or entorhinal-hippocampal neuronal network dysfunction, as measured by an impairment in hippocampal response to entorhinal stimulation. |
2020-08-18 |
2023-08-13 |
rat |
| Chris M Foster, Kristen M Kennedy, David A Hoagey, Karen M Rodrigu. The role of hippocampal subfield volume and fornix microstructure in episodic memory across the lifespan. Hippocampus. vol 29. issue 12. 2020-07-10. PMID:31334583. |
the contribution of mtl to episodic memory is complex and depends upon the interplay among hippocampal subfields and surrounding structures that participate in anatomical connectivity to the cortex through inputs (parahippocampal and entorhinal cortices) and outputs (fornix). |
2020-07-10 |
2023-08-13 |
Not clear |
| Eirik S Nilssen, Thanh P Doan, Maximiliano J Nigro, Shinya Ohara, Menno P Witte. Neurons and networks in the entorhinal cortex: A reappraisal of the lateral and medial entorhinal subdivisions mediating parallel cortical pathways. Hippocampus. vol 29. issue 12. 2020-07-10. PMID:31408260. |
we suggest that entorhinal inputs provide the hippocampus with high-order complex representations of the external environment, its stability, as well as apparent changes either as an inherent feature of a biological environment or as the result of navigating the environment. |
2020-07-10 |
2023-08-13 |
Not clear |
| Kamil A Grajski, Steven L Bressle. Differential medial temporal lobe and default-mode network functional connectivity and morphometric changes in Alzheimer's disease. NeuroImage. Clinical. vol 23. 2020-06-29. PMID:31158694. |
in early mild cognitive impairment these changes involved medial temporal lobe regions of transentorhinal, perirhinal and entorhinal cortices (associated with the earliest stages of neurofibrillary changes in alzheimer's disease), hippocampus, parahippocampal gyrus and temporal pole, and cortical regions comprising or co-activated with the default-mode network, including rostral and medial prefrontal cortex, anterior cingulate cortex, precuneus and inferior temporal cortex. |
2020-06-29 |
2023-08-13 |
human |
| Jessica Robin, Yeshith Rai, Mikaeel Valli, Rosanna K Olse. Category specificity in the medial temporal lobe: A systematic review. Hippocampus. vol 29. issue 4. 2020-05-19. PMID:30155943. |
theoretical accounts of medial temporal lobe (mtl) function ascribe different functions to subregions of the mtl including perirhinal, entorhinal, parahippocampal cortices, and the hippocampus. |
2020-05-19 |
2023-08-13 |
Not clear |
| Wesley Clawson, Ana F Vicente, Maëva Ferraris, Christophe Bernard, Demian Battaglia, Pascale P Quilichin. Computing hubs in the hippocampus and cortex. Science advances. vol 5. issue 6. 2020-04-30. PMID:31249875. |
using high-density recordings in the hippocampus, medial entorhinal, and medial prefrontal cortex of the rat, we identify computing substates where specific computing hub neurons perform well-defined storage and sharing operations in a brain state-dependent manner. |
2020-04-30 |
2023-08-13 |
rat |
| Tianyi Li, Angelo Arleo, Denis Sheynikhovic. Modeling place cells and grid cells in multi-compartment environments: Entorhinal-hippocampal loop as a multisensory integration circuit. Neural networks : the official journal of the International Neural Network Society. vol 121. 2020-03-10. PMID:31526953. |
hippocampal place cells and entorhinal grid cells are thought to form a representation of space by integrating internal and external sensory cues. |
2020-03-10 |
2023-08-13 |
Not clear |
| Sarojini M Attili, Marcos F M Silva, Thuy-Vi Nguyen, Giorgio A Ascol. Cell numbers, distribution, shape, and regional variation throughout the murine hippocampal formation from the adult brain Allen Reference Atlas. Brain structure & function. vol 224. issue 8. 2020-02-24. PMID:31444616. |
while this strategy is directly applicable to any regions of the mouse brain, we first deploy it here on the closed-loop circuit of the hippocampal formation: the medial and lateral entorhinal cortices; dentate gyrus (dg); areas cornu ammonis 3 (ca3), ca2, and ca1; and dorsal and ventral subiculum. |
2020-02-24 |
2023-08-13 |
mouse |
| Jacob Ls Bellmund, Lorena Deuker, Christian F Doelle. Mapping sequence structure in the human lateral entorhinal cortex. eLife. vol 8. 2020-02-03. PMID:31383256. |
we previously demonstrated that the hippocampus maps spatial and temporal distances between events encountered along a route through a virtual city (deuker et al., 2016), but the content of entorhinal mnemonic representations remains unclear. |
2020-02-03 |
2023-08-13 |
human |
| Siobhan Robinson, Lauren Granata, Robert D Hienz, Catherine M Davi. Temporary inactivation of the medial prefrontal cortex impairs the formation, but not the retrieval of social odor recognition memory in rats. Neurobiology of learning and memory. vol 161. 2019-12-24. PMID:30953696. |
the hippocampus, medial dorsal thalamus and the perirhinal and entorhinal cortices are essential for visual recognition memory whereas the neural substrates underlying olfactory recognition memories are less well characterized. |
2019-12-24 |
2023-08-13 |
rat |
| Antonio Caretta, Daniela Cevolani, Giuseppe Luppino, Massimo Matelli, Roberto Tirindell. Characterization and Regional Distribution of a Class of Synapses with Highly Concentrated cAMP Binding Sites in the Rat Brain. The European journal of neuroscience. vol 3. issue 7. 2019-11-20. PMID:12106475. |
saf-camp labelling is prominent in well defined regions of the rat brain: (i) the frontal and entorhinal areas of the cortex; (ii) the field ca1 of the hippocampus; (iii) the olfactory system; (iv) the medial nuclei of the thalamus; (v) the parabrachial nuclei and other less defined regions of the reticular substance; (vi) the substantia gelatinosa of rolando in the spinal cord; and (vii) the neo- and paleocerebellum in the purkinje cell layer, the archicerebellum in the granular cell layer. |
2019-11-20 |
2023-08-12 |
rat |
| Tim James Viney, Minas Salib, Abhilasha Joshi, Gunes Unal, Naomi Berry, Peter Somogy. Shared rhythmic subcortical GABAergic input to the entorhinal cortex and presubiculum. eLife. vol 7. 2019-07-22. PMID:29620525. |
spatial navigation and context-dependent episodic memories are represented in several interconnected regions including the hippocampal and entorhinal cortices, but the cellular mechanisms for their dynamic coupling remain to be defined. |
2019-07-22 |
2023-08-13 |
mouse |
| Tim James Viney, Minas Salib, Abhilasha Joshi, Gunes Unal, Naomi Berry, Peter Somogy. Shared rhythmic subcortical GABAergic input to the entorhinal cortex and presubiculum. eLife. vol 7. 2019-07-22. PMID:29620525. |
orchid cells discharge near the peak of hippocampal and entorhinal theta oscillations, couple to entorhinal gamma oscillations, and target subpopulations of extra-hippocampal gabaergic interneurons. |
2019-07-22 |
2023-08-13 |
mouse |
| Akinori Nakamura, Pablo Cuesta, Alberto Fernández, Yutaka Arahata, Kaori Iwata, Izumi Kuratsubo, Masahiko Bundo, Hideyuki Hattori, Takashi Sakurai, Koji Fukuda, Yukihiko Washimi, Hidetoshi Endo, Akinori Takeda, Kersten Diers, Ricardo Bajo, Fernando Maestú, Kengo Ito, Takashi Kat. Electromagnetic signatures of the preclinical and prodromal stages of Alzheimer's disease. Brain : a journal of neurology. vol 141. issue 5. 2019-07-08. PMID:29522156. |
the results demonstrated that regional spectral patterns of resting state activity could be separated into several types of meg signatures as follows: (i) the effects of amyloid-β deposition were expressed as the alpha band power augmentation in medial frontal areas; (ii) the delta band power increase in the same region was associated with disease progression within the alzheimer's disease continuum and was correlated with entorhinal atrophy and an alzheimer's disease-like regional decrease in glucose metabolism; and (iii) the global theta power augmentation, which was previously considered to be an alzheimer's disease-related eeg/meg signature, was associated with general cognitive decline and hippocampal atrophy, but was not specific to alzheimer's disease because these changes could be observed in the absence of amyloid-β deposition. |
2019-07-08 |
2023-08-13 |
Not clear |
| Yvonne S Davidson, Andrew Robinson, Vee P Prasher, David M A Man. The age of onset and evolution of Braak tangle stage and Thal amyloid pathology of Alzheimer's disease in individuals with Down syndrome. Acta neuropathologica communications. vol 6. issue 1. 2019-06-04. PMID:29973279. |
tau pathology usually commenced after 35 years of age, initially involving not only entorhinal areas and hippocampus but also subcortical regions such as locus caeruleus (lc) and dorsal raphe nucleus (drn). |
2019-06-04 |
2023-08-13 |
Not clear |
| Yvonne S Davidson, Andrew Robinson, Vee P Prasher, David M A Man. The age of onset and evolution of Braak tangle stage and Thal amyloid pathology of Alzheimer's disease in individuals with Down syndrome. Acta neuropathologica communications. vol 6. issue 1. 2019-06-04. PMID:29973279. |
we found no evidence that tau pathology might commence within the brain in ds before amyloid deposition had occurred, but there was limited data that suggests tau pathology in lc or drn might predate that in entorhinal areas and hippocampus or at least be coincident. |
2019-06-04 |
2023-08-13 |
Not clear |
| Russell A Epstein, Eva Zita Patai, Joshua B Julian, Hugo J Spier. The cognitive map in humans: spatial navigation and beyond. Nature neuroscience. vol 20. issue 11. 2019-05-09. PMID:29073650. |
specifically, these studies indicate that (i) the human hippocampus and entorhinal cortex support map-like spatial codes, (ii) posterior brain regions such as parahippocampal and retrosplenial cortices provide critical inputs that allow cognitive maps to be anchored to fixed environmental landmarks, and (iii) hippocampal and entorhinal spatial codes are used in conjunction with frontal lobe mechanisms to plan routes during navigation. |
2019-05-09 |
2023-08-13 |
human |
| Ling-Yun Fan, Ya-Mei Lai, Ta-Fu Chen, Yung-Chin Hsu, Pin-Yu Chen, Kuo-Zhou Huang, Ting-Wen Cheng, Wen-Yi Isaac Tseng, Mau-Sun Hua, Ya-Fang Chen, Ming-Jang Chi. Diminution of context association memory structure in subjects with subjective cognitive decline. Human brain mapping. vol 39. issue 6. 2019-03-26. PMID:29516634. |
the results demonstrated that scd subjects showed significant cortical atrophy in their bilateral parahippocampus and perirhinal and the left entorhinal cortices but not in their hippocampal regions. |
2019-03-26 |
2023-08-13 |
human |