| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D T Krieger, W R Crowley, T L O'Donohue, D M Jacobowit. Effects of food restriction on the periodicity of corticosteroids in plasma and on monoamine concentrations in discrete brain nuclei. Brain research. vol 188. issue 1. 1980-07-22. PMID:7370751. |
the concentrations of plasma corticosteroids and of norepinephrine, dopamine and serotonin in microdissected brain regions were measured at 08.00, 12.00 and 20.00 h in male rats fed ad libitum and in rats whose food intake was restricted to 09.30-11.30 h. in ad libitum fed animals, plasma corticosteroids were lowest at 08.00 and highest at 20.00 h. as demonstrated previously, restriction of food availability was associated with appearance of a peak in corticosteroids at 08.00 h. in ad libitum fed animals, serotonin and dopamine concentrations in the median eminence were higher at 20.00 than at 08.00 h. restriction of food availability significantly decreased the levels of these neurotransmitters at 20.00 h. in the paraventricular nucleus, amygdala, and hippocampus of ad libitum fed animals, serotonin levels were lower at 20.00 than at 08.00 or 12.00 h. in food-shifted animals, this pattern was reversed so that lowest levels of serotonin occured at 08.00 and markedly elevated levels were observed at 12.00 and 20.00 h. no changes were noted in norepinephrine content of the median eminence or paraventricular nucleus of ad libitum fed or food restricted animals. |
1980-07-22 |
2023-08-12 |
rat |
| R Samanin, T Mennini, A Ferraris, C Bendotti, F Borsin. Hyper- and hyposensitivity of central serotonin receptors:[3H]serotonin binding and functional studies in the rat. Brain research. vol 189. issue 2. 1980-07-12. PMID:7189434. |
methergoline caused no changes of [3h)5-ht binding in any brain area examined when given for 14 days but 28-day treatment led to a significant increase in the striatum, hippocampus and cortex. |
1980-07-12 |
2023-08-12 |
rat |
| D D Savage, J Mendels, A Fraze. Monoamine oxidase inhibitors and serotonin uptake inhibitors: differential effects on [3H]serotonin binding sites in rat brain. The Journal of pharmacology and experimental therapeutics. vol 212. issue 2. 1980-03-27. PMID:7351637. |
treatment with inhibitors of serotonin uptake did not change the specific binding of [3h]serotonin in either cerebral cortex or hippocampus, nor did it produce any consistent alterations in the concentration of serotonin in the cerebral cortex. |
1980-03-27 |
2023-08-12 |
rat |
| C Dude, G Dude, K Andrea. [Role of the serotoninergic raphe-hippocampus system for the antinocifensive effect of morphine]. Acta biologica et medica Germanica. vol 38. issue 4. 1980-03-17. PMID:525141. |
topical microinjections of serotonin into the dorsal hippocampus increased morphine analgesia in a dose-dependent fashion, while application into the striatum had no effect. |
1980-03-17 |
2023-08-11 |
Not clear |
| M H Van Woert, A Plaitakis, E C Hwang, S Ber. Effect of thiamine deficiency on brain serotonin turnover. Brain research. vol 179. issue 1. 1980-02-15. PMID:509224. |
however, increased 5-ht synthesis in the cerebellum, hypothalamus, striatum, hippocampus and cerebral cortex was demonstrated by measurement of 5-ht accumulation after inhibition of brain monoamine oxidase. |
1980-02-15 |
2023-08-11 |
rat |
| M K Steele, D Rowland, H Molt. Initiation of maternal behavior in the rat: possible involvement of limbic norepinephrine. Pharmacology, biochemistry, and behavior. vol 11. issue 2. 1980-01-24. PMID:504291. |
hypothalamic ne levels, as well as dopamine and serotonin concentrations in cortex, hippocampus and hypothalamus, were not significantly affected by these manipulations. |
1980-01-24 |
2023-08-11 |
rat |
| C A Marsde. Evidence for the release of hippocampal 5-hydroxytryptamine by alpha-methyltryptamine [proceedings]. British journal of pharmacology. vol 67. issue 3. 1980-01-19. PMID:497560. |
evidence for the release of hippocampal 5-hydroxytryptamine by alpha-methyltryptamine [proceedings]. |
1980-01-19 |
2023-08-11 |
Not clear |
| C A Yates, J Herber. The effects of different photoperiods on circadian 5-HT rhythms in regional brain areas and their modulation by pinealectomy, melatonin and oestradiol. Brain research. vol 176. issue 2. 1980-01-19. PMID:497810. |
differential circadian rhythms in 5-ht levels were found in the hypothalamus and pineal (but not in the cortex, hippocampus or midbrain) in ferrets kept in either long (14 h light/10 h dark) or short (8 h light/16 h dark) photoperiods. |
1980-01-19 |
2023-08-11 |
Not clear |
| b' U Scapagnini, G Nistic\\xc3\\xb. Serotoninergic involvement in the regulation of circadian rhythms of hypothalamic-pituitary adrenal and prolactin axis. Annali dell\'Istituto superiore di sanita. vol 14. issue 1. 1979-12-29. PMID:227305.' |
a modification of the amplitude of the plasma corticosterone circadian variations also occurs after more selective destruction of some nuclei (n. centralis superior and n. raphe dorsalis) which reduced 5-ht concentration both in the hypothalamus and the hippocampus. |
1979-12-29 |
2023-08-11 |
rat |
| J F Deakin, S E File, J R Hyde, N K Macleo. Ascending 5-HT pathways and behavioural habituation. Pharmacology, biochemistry, and behavior. vol 10. issue 5. 1979-12-18. PMID:493286. |
microinjections of 5,7 -dihydroxytryptamine into both the dorsal and median raphe nuclei resulted in 70-85% depletions in striatal and hippocampal 5-ht concentrations but did not affect habituation of orienting in the lick-distraction test, habituation of activity in an open-field or habituation of exploration in the holeboard test. |
1979-12-18 |
2023-08-11 |
rat |
| I Vermes, G Telegd. Effect of stress on activity of the serotoninergic system in limbic brain structures and its correlation with pituitary-adrenal function in the rat. Acta physiologica Academiae Scientiarum Hungaricae. vol 49. issue 1. 1979-11-28. PMID:755331. |
in the hippocampus and the septum the 5-ht or 5-hiia content was unaffected by either type of stress. |
1979-11-28 |
2023-08-11 |
rat |
| M E Benwell, D J Balfou. Effects of nicotine administration and its withdrawal on plasma corticosterone and brain 5-hydroxyindoles. Psychopharmacology. vol 63. issue 1. 1979-10-24. PMID:112625. |
hippocampal 5-hydroxytryptamine (5-ht) was reduced in nicotine-treated rats, significantly so in those treated for more than 20 days. |
1979-10-24 |
2023-08-11 |
rat |
| K T Borer, M E Trulson, L R Kuhn. Role of limbic system in the control of hamster growth. Brain research bulletin. vol 4. issue 2. 1979-10-17. PMID:466511. |
both knife cuts accelerated somatic growth and were associated (as well as septal lesions) with significant depletions of serotonin (-27 to -57%) and norepinephrine (-27 to -60%) in the hippocampus, with less consistent depletions of these monoamines in the cerebral cortex, and with no changes in regional dopamine content. |
1979-10-17 |
2023-08-11 |
Not clear |
| C A Marsde. Long term effects of p-chloroamphetamine on hippocampal 5-hydroxytryptamine release [proceedings]. British journal of pharmacology. vol 66. issue 1. 1979-09-25. PMID:454916. |
long term effects of p-chloroamphetamine on hippocampal 5-hydroxytryptamine release [proceedings]. |
1979-09-25 |
2023-08-11 |
Not clear |
| R F Smit. Mediation of footshock sensitivity by serotonergic projection to hippocampus. Pharmacology, biochemistry, and behavior. vol 10. issue 3. 1979-08-29. PMID:156370. |
experiment 2 tested the effects of hippocampal lesion on the 5-htp effect in animals when serotonin depletion produced by either pcpa or septal lesion. |
1979-08-29 |
2023-08-11 |
Not clear |
| R F Smit. Mediation of footshock sensitivity by serotonergic projection to hippocampus. Pharmacology, biochemistry, and behavior. vol 10. issue 3. 1979-08-29. PMID:156370. |
the results suggest that hippocampus may be an important site of action of serotonin in modulating reactivity to footshock, and that failure of raphe lesions to increase reactivity may be due to failure to adequately deplete hippocampal serotonin. |
1979-08-29 |
2023-08-11 |
Not clear |
| A Pletscher, A Laubscher, M Graf, A Sane. Blood platelets as models for central 5-hydroxytryptaminergic neurons. Annales de biologie clinique. vol 37. issue 1. 1979-07-16. PMID:443611. |
those with dense 5ht innervation and the hippocampus the 5ht receptors show a reaction to drugs which is partially different from that of the platelet receptors. |
1979-07-16 |
2023-08-11 |
Not clear |
| V A Gusel', I B Mikhailo. [Increase in the activity of an epileptogenic focus in frog hippocampus as a result of kynurenines and its reduction by serotonin]. Biulleten' eksperimental'noi biologii i meditsiny. vol 87. issue 2. 1979-05-16. PMID:311225. |
[increase in the activity of an epileptogenic focus in frog hippocampus as a result of kynurenines and its reduction by serotonin]. |
1979-05-16 |
2023-08-11 |
Not clear |
| E J Marco, J L Mee. The effects of antidepressants on serotonin turnover in discrete regions of rat brain. Naunyn-Schmiedeberg's archives of pharmacology. vol 306. issue 1. 1979-05-16. PMID:311440. |
serotonin (5-ht) turnover was measured in hypothalamus, hippocampus, cortex, septum and nucleus caudatus of rats after acute or chronic treatment with antidepressants. |
1979-05-16 |
2023-08-11 |
rat |
| G R Van Loon, E B De Souza, C Ki. Alterations in brain dopamine and serotonin metabolism during the development of tolerance to human beta-endorphin in rats. Canadian journal of physiology and pharmacology. vol 56. issue 6. 1979-05-16. PMID:743624. |
the initial injection of beta-endorphin results in increases in the dopamine metabolites, 3,4-dihydroxyphenylacetic acid (dopac) and homovanillic acid (hva), in neostriatum, as well as increases in the serotonin metabolite, 5-hydroxyindoleacetic acid (5-hiaa), in hypothalamus and brainstem and a decrease in 5-hiaa in hippocampus. |
1979-05-16 |
2023-08-11 |
human |