| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bo Zhang, Xijian Peng, Xiumei Sun, Yuanming Guo, Tiejun L. Environmentally-relevant concentrations of the antipsychotic drugs sulpiride and clozapine induce abnormal dopamine and serotonin signaling in zebrafish brain. Scientific reports. vol 12. issue 1. 2022-10-26. PMID:36289270. |
both drugs induced abnormal mrna and protein levels of important functional molecules of the da and 5-ht signaling pathways in both telencephalon and diencephalon, as shown by the abnormal transcriptional levels of th, dat, dr d1, dr d2, mao, tph, serotonin transporter (sert), 5-htr 1aa, 5-htr 1b, 5-thr 2aa, and 5-htr 2b, and the abnormal translational levels of dat, dr d2, sert, 5-htr 1a, 5-htr 1b, and 5-htr 2b. |
2022-10-26 |
2023-08-14 |
zebrafish |
| Mohamed Z Elhussiny, Haruka Nishimura, Phuong V Tran, Shogo Haraguchi, Elizabeth R Gilbert, Mark A Cline, Takashi Bungo, Mitsuhiro Furuse, Vishwajit S Chowdhur. Intracerebroventricular injection of taurine induces hypothermia through modifying monoaminergic pathways in chicks. European journal of pharmacology. 2022-06-13. PMID:35697149. |
similarly, taurine treatment induced increases in serotonin (5-ht) and its metabolite 5-hydroxyindoleacetic acid in the diencephalon. |
2022-06-13 |
2023-08-14 |
Not clear |
| Ruth I Versteeg, Karin E Koopman, Jan Booij, Mariëtte T Ackermans, Unga A Unmehopa, Eric Fliers, Susanne E la Fleur, Mireille J Serli. Serotonin Transporter Binding in the Diencephalon Is Reduced in Insulin-Resistant Obese Humans. Neuroendocrinology. vol 105. issue 2. 2018-04-25. PMID:27626923. |
serotonin transporter binding in the diencephalon is reduced in insulin-resistant obese humans. |
2018-04-25 |
2023-08-13 |
Not clear |
| Gianfranco Bellipanni, Elke Rink, Laure Bally-Cui. Cloning of two tryptophan hydroxylase genes expressed in the diencephalon of the developing zebrafish brain. Mechanisms of development. vol 119 Suppl 1. 2016-04-23. PMID:14516688. |
the co-expression of tphd1, tphd2 and 5-ht in the zebrafish diencephalon appears in striking contrast to the situation in mammals, where diencephalic serotonin results from re-uptake rather than from local production. |
2016-04-23 |
2023-08-12 |
zebrafish |
| Junki Yoshida, Edi Erwan, Vishwajit Sur Chowdhury, Yumi Ogino, Asako Shigemura, D Michael Denbow, Mitsuhiro Furus. Comparison of centrally injected tryptophan-related substances inducing sedation in acute isolation stress-induced neonatal chicks. Pharmacology, biochemistry, and behavior. vol 129. 2015-10-09. PMID:25459103. |
additionally, plasma corticosterone, dopamine, 5-ht, and its metabolite 5-hydroxyindoleacetic acid concentrations were increased in the diencephalon of the 5-ht treated group compared with other groups. |
2015-10-09 |
2023-08-13 |
chicken |
| M O Melancon, D Lorrain, I J Dionn. Exercise and sleep in aging: emphasis on serotonin. Pathologie-biologie. vol 62. issue 5. 2015-06-09. PMID:25104243. |
it is known that serotonin released into diencephalon and cerebrum might play a key inhibitory role to help promote sleep, likely through an active inhibition of supraspinal neural networks. |
2015-06-09 |
2023-08-13 |
Not clear |
| R Ye, A M D Carneiro, D Airey, E Sanders-Bush, R W Williams, L Lu, J Wang, B Zhang, R D Blakel. Evaluation of heritable determinants of blood and brain serotonin homeostasis using recombinant inbred mice. Genes, brain, and behavior. vol 13. issue 3. 2014-11-07. PMID:24102824. |
we determined levels of 5-ht and 5-hydroxyindoleacetic acid from whole blood, midbrain and thalamus/hypothalamus (diencephalon) of 38 bxd lines and both sexes. |
2014-11-07 |
2023-08-12 |
mouse |
| Guiqi Ren, Song Li, Hanbing Zhong, Shuo Li. Zebrafish tyrosine hydroxylase 2 gene encodes tryptophan hydroxylase. The Journal of biological chemistry. vol 288. issue 31. 2013-10-21. PMID:23754283. |
in this study, we present evidence that th2 co-localizes with serotonin in the ventral diencephalon and caudal hypothalamus in zebrafish embryos. |
2013-10-21 |
2023-08-12 |
mouse |
| Karin E Koopman, Susanne E la Fleur, Eric Fliers, Mireille J Serlie, Jan Booi. Assessing the optimal time point for the measurement of extrastriatal serotonin transporter binding with 123I-FP-CIT SPECT in healthy, male subjects. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 53. issue 7. 2012-09-13. PMID:22627000. |
however, recent studies suggest that this tracer may be used also to assess binding to monoamine transporters in the midbrain or diencephalon, which may reflect predominantly serotonin transporter (sert) binding. |
2012-09-13 |
2023-08-12 |
human |
| Shogo Haraguchi, Teppei Koyama, Itaru Hasunuma, Shin-ichiro Okuyama, Takayoshi Ubuka, Sakae Kikuyama, Jean-Luc Do Rego, Hubert Vaudry, Kazuyoshi Tsutsu. Acute stress increases the synthesis of 7α-hydroxypregnenolone, a new key neurosteroid stimulating locomotor activity, through corticosterone action in newts. Endocrinology. vol 153. issue 2. 2012-03-27. PMID:22128027. |
a 30-min restraint stress or central administration of 7α-oh preg increased serotonin concentrations in the diencephalon. |
2012-03-27 |
2023-08-12 |
Not clear |
| Jian-Sheng Lin, Christelle Anaclet, Olga A Sergeeva, Helmut L Haa. The waking brain: an update. Cellular and molecular life sciences : CMLS. vol 68. issue 15. 2011-09-09. PMID:21318261. |
these evolutionary conserved activating systems build a network in the brainstem, midbrain, and diencephalon that contains the neurotransmitters and neuromodulators glutamate, histamine, acetylcholine, the catecholamines, serotonin, and some neuropeptides orchestrating the different behavioral states. |
2011-09-09 |
2023-08-12 |
Not clear |
| Kelly P Cosgrove, Karen Tellez-Jacques, Brian Pittman, Ismene Petrakis, Ronald M Baldwin, Gilles Tamagnan, John Seibyl, Thomas Kosten, Julie K Stale. Dopamine and serotonin transporter availability in chronic heroin users: a [¹²³I]β-CIT SPECT imaging study. Psychiatry research. vol 184. issue 3. 2011-02-03. PMID:21050726. |
heroin users had statistically similar striatal da and brainstem and diencephalon 5-ht transporter availability compared with controls. |
2011-02-03 |
2023-08-12 |
Not clear |
| Sachiko Katayama, Kazutaka Shigemi, Mark A Cline, Mitsuhiro Furus. Intracerebroventricular injection of orexin-A stimulates monoamine metabolism but not HPA axis in neonatal chicks. Neuroscience letters. vol 484. issue 2. 2011-01-13. PMID:20727938. |
in experiment 2, the concentrations of monoamines (norepinephrine, dopamine and serotonin), their metabolites, and their metabolic turnover rates in the telencephalon, mesencephalon, and diencephalon were investigated. |
2011-01-13 |
2023-08-12 |
Not clear |
| Eric Marvin, Karie Scrogin, Bertalan Dudá. Morphology and distribution of neurons expressing serotonin 5-HT1A receptors in the rat hypothalamus and the surrounding diencephalic and telencephalic areas. Journal of chemical neuroanatomy. vol 39. issue 4. 2010-06-29. PMID:20080175. |
while previous studies have shown the presence of 5-ht(1a) receptors in several regions of the rat brain, there is no detailed map of the cellular distribution of 5-ht(1a) receptors in the rat diencephalon. |
2010-06-29 |
2023-08-12 |
rat |
| Eric Marvin, Karie Scrogin, Bertalan Dudá. Morphology and distribution of neurons expressing serotonin 5-HT1A receptors in the rat hypothalamus and the surrounding diencephalic and telencephalic areas. Journal of chemical neuroanatomy. vol 39. issue 4. 2010-06-29. PMID:20080175. |
in order to characterize the distribution and morphology of the neurons containing 5-ht(1a) receptors in the diencephalon and the adjacent telencephalic areas, single label immunohistochemistry was utilized. |
2010-06-29 |
2023-08-12 |
rat |
| Eric Marvin, Karie Scrogin, Bertalan Dudá. Morphology and distribution of neurons expressing serotonin 5-HT1A receptors in the rat hypothalamus and the surrounding diencephalic and telencephalic areas. Journal of chemical neuroanatomy. vol 39. issue 4. 2010-06-29. PMID:20080175. |
medium-sized 5-ht(1a)-ir neurons with triangular or round-shaped somata were widely distributed in the diencephalon, populating the zona incerta, lateral hypothalamic area, anterior hypothalamic nucleus, substantia innominata, dorsomedial and premamillary nuclei, paraventricular nucleus and bed nucleus of stria terminalis. |
2010-06-29 |
2023-08-12 |
rat |
| Eric Marvin, Karie Scrogin, Bertalan Dudá. Morphology and distribution of neurons expressing serotonin 5-HT1A receptors in the rat hypothalamus and the surrounding diencephalic and telencephalic areas. Journal of chemical neuroanatomy. vol 39. issue 4. 2010-06-29. PMID:20080175. |
the present study provides schematic mapping of 5-ht(1a)-ir neurons in the rat diencephalon. |
2010-06-29 |
2023-08-12 |
rat |
| Faiza Bux, Adhil Bhagwandin, Kjell Fuxe, Paul R Mange. Organization of cholinergic, putative catecholaminergic and serotonergic nuclei in the diencephalon, midbrain and pons of sub-adult male giraffes. Journal of chemical neuroanatomy. vol 39. issue 3. 2010-05-11. PMID:19808092. |
the current study describes the nuclear organization and neuronal morphology of the cholinergic, putative catecholaminergic and serotonergic systems within the diencephalon, midbrain and pons of the giraffe using immunohistochemistry for choline acetyltransferase, tyrosine hydroxylase and serotonin. |
2010-05-11 |
2023-08-12 |
Not clear |
| Kelly P Cosgrove, Erica Krantzler, Erin B Frohlich, Stephanie Stiklus, Brian Pittman, Gilles D Tamagnan, Ronald M Baldwin, Frederic Bois, John P Seibyl, John H Krystal, Stephanie S O'Malley, Julie K Stale. Dopamine and serotonin transporter availability during acute alcohol withdrawal: effects of comorbid tobacco smoking. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 10. 2009-10-29. PMID:19440191. |
5-ht transporter availability was also significantly higher in alcohol drinkers vs controls in the brainstem (25%, p=0.001) and the diencephalon (8%, p=0.01). |
2009-10-29 |
2023-08-12 |
Not clear |
| Kelly P Cosgrove, Erica Krantzler, Erin B Frohlich, Stephanie Stiklus, Brian Pittman, Gilles D Tamagnan, Ronald M Baldwin, Frederic Bois, John P Seibyl, John H Krystal, Stephanie S O'Malley, Julie K Stale. Dopamine and serotonin transporter availability during acute alcohol withdrawal: effects of comorbid tobacco smoking. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 10. 2009-10-29. PMID:19440191. |
this elevation was restricted to alcohol drinking nonsmokers with higher da transporter availability in the striatum (26%, p=0.006), and higher 5-ht transporter availability in the diencephalon (26%, p=0.04) and brainstem (42%, p<0.0002). |
2009-10-29 |
2023-08-12 |
Not clear |