| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Telegdy, I Verme. Effect of adrenocortical hormones on activity of the serotoninergic system in limbic structures in rats. Neuroendocrinology. vol 18. issue 1. 1975-10-11. PMID:1143627. |
corticosterone administration normalized the 5-ht and 5-hiaa content in the hypothalamus and mesencephalon in adrenalectomized rats. |
1975-10-11 |
2023-08-11 |
rat |
| G Telegdy, I Verme. Effect of adrenocortical hormones on activity of the serotoninergic system in limbic structures in rats. Neuroendocrinology. vol 18. issue 1. 1975-10-11. PMID:1143627. |
tritiated 5-ht uptake was lower in the hypothalamus and mesencephalon in adrenalectomized rats. |
1975-10-11 |
2023-08-11 |
rat |
| D W Gallager, E Sanders-Bush, G K Aghajanian, F Sulse. An evaluation of the use of intraventricularly administered [3H]5-hydroxytryptamine as a marker for endogenous brain 5-hydroxytryptamine. Brain research. vol 93. issue 1. 1975-10-10. PMID:1040550. |
moreover, a multiphasic disappearance of [3h]5-ht from whole brain or midbrain was found after the intraventricular injection of the labeled amine. |
1975-10-10 |
2023-08-11 |
Not clear |
| D W Gallager, E Sanders-Bush, G K Aghajanian, F Sulse. An evaluation of the use of intraventricularly administered [3H]5-hydroxytryptamine as a marker for endogenous brain 5-hydroxytryptamine. Brain research. vol 93. issue 1. 1975-10-10. PMID:1040550. |
however, after the intraventricular injection of [3h]tryptophan, the levels of [3h]5-ht in midbrain declined in a monophasic manner. |
1975-10-10 |
2023-08-11 |
Not clear |
| D W Gallager, E Sanders-Bush, G K Aghajanian, F Sulse. An evaluation of the use of intraventricularly administered [3H]5-hydroxytryptamine as a marker for endogenous brain 5-hydroxytryptamine. Brain research. vol 93. issue 1. 1975-10-10. PMID:1040550. |
a significant portion of the labeled amine derived from intraventricularly administered [3h]5-ht was resistant to the depleting effect of ro4-1284 or to that elicited by destruction of the midbrain raphe nuclei, both of which caused an almost complete loss of endogenous 5-ht and labeled 5-ht formed from tryptophan. |
1975-10-10 |
2023-08-11 |
Not clear |
| N K Popova, E M Nikulina, V A Arav, N N Kudriavtsev. [The role of serotonin in one of the types of aggressive behavior--"predatory aggression"]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 61. issue 2. 1975-10-07. PMID:124672. |
electrolytic lesion of the midbrain raphe nuclei in rats, lowering serotonin level in the forebrain, elicited mouse-killing behavior. |
1975-10-07 |
2023-08-11 |
rat |
| C Blondaux, M Buda, F Petitjean, J F Pujo. [Hypersomnia by isthmic lesion in cat. Study of the metabolism of cerebral monamines]. Brain research. vol 88. issue 3. 1975-10-07. PMID:1170005. |
this stimulation of the synthesis was simultaneously observed at the level fo serotoninergic cell bodies (anterior part of the raphe system) and of 5-ht terminals (cortex, thalamus, mesencephalon, medulla oblongata). |
1975-10-07 |
2023-08-11 |
cat |
| H Ikeda, J Got. Distribution of monoamine-containing terminals and fibers in the central nervous system of the chicken. Japanese journal of pharmacology. vol 24. issue 6. 1975-09-13. PMID:4463270. |
5-ht containing terminals and fibers also were observed in the mesencephalon and appeared to run rostrally in the medial part of the medial forebrain bundle. |
1975-09-13 |
2023-08-11 |
rat |
| M L Simon, R Georg. Diurnal variations in plasma corticosterone and growth hormone as corrlelated with regional variations in norepinephrine, dopamine and serotonin content of rat brain. Neuroendocrinology. vol 17. issue 2. 1975-09-03. PMID:1169697. |
statistically significant diurnal cycles of serotonin (5-ht) concentration were found in the amygdala and midbrain, significant diurnal alterations in norepinephrine (ne) levels. |
1975-09-03 |
2023-08-11 |
rat |
| M L Simon, R Georg. Diurnal variations in plasma corticosterone and growth hormone as corrlelated with regional variations in norepinephrine, dopamine and serotonin content of rat brain. Neuroendocrinology. vol 17. issue 2. 1975-09-03. PMID:1169697. |
plasma gh changes were found to be directly correlated with midbrain and amygdala 5-ht levels and with da levels of all areas except the amygdala, plasma cs was found to be inversely correlated with striatal and cortical da and with 5-ht levels of amygdala. |
1975-09-03 |
2023-08-11 |
rat |
| S A Lorens, H C Guldber. Regional 5-hydroxytryptamine following selective midbrain raphe lesions in the rat. Brain research. vol 78. issue 1. 1975-08-08. PMID:4458916. |
regional 5-hydroxytryptamine following selective midbrain raphe lesions in the rat. |
1975-08-08 |
2023-08-11 |
rat |
| G Metcalf, J W Thompso. The effect of various amine-depleting drugs on the fever response exhibited by rabbits to bacterial or leucocyte pyrogen. British journal of pharmacology. vol 53. issue 1. 1975-08-04. PMID:123804. |
3 bp significantly (p smaller than 0.01) lowered the concentration of 5-ht in the preoptic/hypothalamic area but had no effect in the midbrain or pons/medulla, whereas lp significantly (p smaller than 0.01) lowered the concentration of 5-ht in the midbrain and pons/medulla but had little effect in the hypothalamus. |
1975-08-04 |
2023-08-11 |
rabbit |
| K Hole, S A Loren. Response to electric shock in rats: effects of selective midbrain raphe lesions. Pharmacology, biochemistry, and behavior. vol 3. issue 1. 1975-07-28. PMID:124065. |
the forebrain serotonin (5-ht) concentrations of rats with lesions in the median (m; n equal to 5), dorsal (d; n equal to 5), and both (dm; n equal to 6) midbrain raphe nuclei were, respectively, 22, 48, and 70% lower than in control animals (n equal to 10). |
1975-07-28 |
2023-08-11 |
rat |
| D Rudman, R K Chawla, B S Katr. Melanotropic activity in extrahypophyseal regions of rodent brain: effect of age, hormones, and drugs. The American journal of physiology. vol 228. issue 4. 1975-07-18. PMID:124136. |
the present study investigated the possible influence of the following factors on the level of melanotropic activity in whole brain, cerebral cortex, cerebellum, midbrain, and brainstem of mouse and rat: age, sex, starvation; and of the following hormones or drugs administered by the intraperitoneal or intracerebral route: norepinephrine, dihydroxyphenylalanine, pargyline, 6-hydroxy-dopamine, alpha-methyltyrosine methyl ester, reserpine, acetylcholine, pilocarpine, atropine, serotonin, p-chlorophenylalanine, pentobarbital, pentylenetetrazol, insulin, melatonin, and cycloheximide. |
1975-07-18 |
2023-08-11 |
mouse |
| E Sanders-Bush, J A Bushing, F Sulse. Long-term effects of p-chloroamphetamine and related drugs on central serotonergic mechanisms. The Journal of pharmacology and experimental therapeutics. vol 192. issue 1. 1975-07-01. PMID:1123726. |
the greatest reductions of 5-ht, tryptophan hydroxylase activity and synaptosomal uptake were found in the midbrain, hippocampus and striatum with less pronounced effects in the hypothalamus, medulla-pons and spinal cord. |
1975-07-01 |
2023-08-11 |
rat |
| A Ito, S M Schanber. Effect of serotonin depletion on the central regulation of the carotid sinus reflex in rats. Japanese heart journal. vol 16. issue 2. 1975-06-06. PMID:123283. |
in rats with the brain serotonin depleted below 10% of control by p-chlorophenylalanine, the reflex pressor response significantly decreased, but the reflex sensitivity was unchanged in any transection regimen, suggesting the decrease originated in the associated hypertension; the infracollicular transection augmented the reflex reaction and sensitivity in both groups, and the medullospinal separation abolished the reflex; it is concluded that the brain serotonin would not be significantly involved in the central regulation of the sympathetic component of the carotid sinus reflex, and that the structure rostral to the midbrain could play an inhibitory role in the integrative regulation. |
1975-06-06 |
2023-08-11 |
rat |
| D Giulian, B S McEwen, L A Pohoreck. Altered development of the rat brain serotonergic system after disruptive neonatal experience. Proceedings of the National Academy of Sciences of the United States of America. vol 71. issue 10. 1975-02-06. PMID:4530288. |
after cold treatment, elevations in 5-hydroxytryptamine levels of a preparation of forebrain plus midbrain could be first detected on postnatal day 16 in both sexes. |
1975-02-06 |
2023-08-11 |
rat |
| S Mosko, B L Jacob. Effect of peripherally administered serotonin on the neuronal activity of midbrain raphe neurons. Brain research. vol 79. issue 2. 1975-01-15. PMID:4418523. |
effect of peripherally administered serotonin on the neuronal activity of midbrain raphe neurons. |
1975-01-15 |
2023-08-11 |
Not clear |
| L D Grant, D V Coscina, S P Grossman, D X Freedma. Muricide after serotonin depleting lesions of midbrain raphé nuclei. Pharmacology, biochemistry, and behavior. vol 1. issue 1. 1974-04-02. PMID:4798086. |
muricide after serotonin depleting lesions of midbrain raphé nuclei. |
1974-04-02 |
2023-08-11 |
Not clear |
| J A Harvey, E M Ga. Septal tryptophan-5-hydroxylase: divergent response to raphe lesions and parachlorophenylalanine. Science (New York, N.Y.). vol 183. issue 4127. 1974-03-22. PMID:4272645. |
destruction of the raphe nuclei in the midbrain led to a large and comparable decrease in both serotonin content and tryptophan hydroxylase activity of the hippocampus. |
1974-03-22 |
2023-08-11 |
Not clear |