| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mitchell Longworth, Mark Connor, Samuel D Banister, Michael Kassio. Synthesis and Pharmacological Profiling of the Metabolites of Synthetic Cannabinoid Drugs APICA, STS-135, ADB-PINACA, and 5F-ADB-PINACA. ACS chemical neuroscience. vol 8. issue 8. 2017-12-22. PMID:28574245. |
synthetic cannabinoids (scs) containing a 1-pentyl-1-h substituted indole or indazole are abused around the world and are associated with an array of serious side effects. |
2017-12-22 |
2023-08-13 |
Not clear |
| Maiko Kusano, Kei Zaitsu, Mayumi Yamanaka, Kazuaki Hisatsune, Tomomi Asano, Kentaro Taki, Yumi Hayashi, Hitoshi Tsuchihashi, Akira Ishi. Development of a mass spectrometric hydroxyl-position determination method for the hydroxyindole metabolites of JWH-018 by GC-MS/MS. Journal of mass spectrometry : JMS. vol 51. issue 5. 2017-12-06. PMID:27194519. |
one of the many issues of designer drugs of abuse like synthetic cannabinoids (scs) such as jwh-018 is that details on their metabolism has yet to be fully elucidated and that multiple metabolites exist. |
2017-12-06 |
2023-08-13 |
mouse |
| Loren Tapp, Jessica G Ramsey, Anita Wen, Roy Geron. Synthetic Cannabinoid and Mitragynine Exposure of Law Enforcement Agents During the Raid of an Illegal Laboratory - Nevada, 2014. MMWR. Morbidity and mortality weekly report. vol 66. issue 47. 2017-12-05. PMID:29190268. |
synthetic cannabinoids (scs), commonly known by the street name "spice," are designer drugs of abuse that mimic the psychoactive effects of marijuana. |
2017-12-05 |
2023-08-13 |
Not clear |
| Szilvia Kassai, Judit Nóra Pintér, József Rácz, Brigitta Böröndi, Tamás Tóth-Karikó, Kitti Kerekes, V Anna Gyarmath. Assessing the experience of using synthetic cannabinoids by means of interpretative phenomenological analysis. Harm reduction journal. vol 14. issue 1. 2017-11-22. PMID:28187774. |
one of the largest groups of nps is synthetic cannabinoids (scs), which are intended as a replacement to cannabis. |
2017-11-22 |
2023-08-13 |
Not clear |
| Samuel D Banister, Mitchell Longworth, Richard Kevin, Shivani Sachdev, Marina Santiago, Jordyn Stuart, James B C Mack, Michelle Glass, Iain S McGregor, Mark Connor, Michael Kassio. Pharmacology of Valinate and tert-Leucinate Synthetic Cannabinoids 5F-AMBICA, 5F-AMB, 5F-ADB, AMB-FUBINACA, MDMB-FUBINACA, MDMB-CHMICA, and Their Analogues. ACS chemical neuroscience. vol 7. issue 9. 2017-10-27. PMID:27421060. |
indole and indazole synthetic cannabinoids (scs) featuring l-valinate or l-tert-leucinate pendant group have recently emerged as prevalent recreational drugs, and their use has been associated with serious adverse health effects. |
2017-10-27 |
2023-08-13 |
rat |
| Florian Franz, Verena Angerer, Hanna Jechle, Melanie Pegoro, Harald Ertl, Georg Weinfurtner, David Janele, Christian Schlögl, Matthias Friedl, Stefan Gerl, Reinhard Mielke, Ralf Zehnle, Matthias Wagner, Bjoern Moosmann, Volker Auwärte. Immunoassay screening in urine for synthetic cannabinoids - an evaluation of the diagnostic efficiency. Clinical chemistry and laboratory medicine. vol 55. issue 9. 2017-08-21. PMID:28130957. |
the abuse of synthetic cannabinoids (scs) as presumed legal alternative to cannabis poses a great risk to public health. |
2017-08-21 |
2023-08-13 |
Not clear |
| Andrew L Ninnemann, Hye Jeong Choi, Gregory L Stuart, Jeff R Templ. Longitudinal Predictors of Synthetic Cannabinoid Use in Adolescents. Pediatrics. vol 139. issue 4. 2017-08-03. PMID:28289139. |
synthetic cannabinoids (scs) are a large, heterogeneous group of chemicals that are structurally similar to δ-9-tetrahydrocannabinol. |
2017-08-03 |
2023-08-13 |
Not clear |
| Andrew L Ninnemann, Hye Jeong Choi, Gregory L Stuart, Jeff R Templ. Longitudinal Predictors of Synthetic Cannabinoid Use in Adolescents. Pediatrics. vol 139. issue 4. 2017-08-03. PMID:28289139. |
many scs are high-efficacy full agonists of the cb1 and/or cb2 cannabinoid receptors, resulting in a potent group of chemicals with a variety of negative health effects, including death. |
2017-08-03 |
2023-08-13 |
Not clear |
| T W Grim, A J Morales, B F Thomas, J L Wiley, G W Endres, S S Negus, A H Lichtma. Apparent CB The Journal of pharmacology and experimental therapeutics. vol 362. issue 1. 2017-08-01. PMID:28442584. |
apparent cb synthetic cannabinoids (scs) represent an emerging class of abused drugs associated with psychiatric complications and other substantial health risks. |
2017-08-01 |
2023-08-13 |
human |
| R Solimini, F P Busardò, M C Rotolo, S Ricci, L Mastrobattista, C Mortali, S Graziano, M Pellegrini, N M di Luca, I Palm. Hepatotoxicity associated to synthetic cannabinoids use. European review for medical and pharmacological sciences. vol 21. issue 1 Suppl. 2017-07-26. PMID:28379600. |
synthetic cannabinoids (scs) are psychotropic compounds, chemically created in laboratory to mimic cannabinergic brain activity of delta-9 tetrahydrocannabinol. |
2017-07-26 |
2023-08-13 |
Not clear |
| R Solimini, F P Busardò, M C Rotolo, S Ricci, L Mastrobattista, C Mortali, S Graziano, M Pellegrini, N M di Luca, I Palm. Hepatotoxicity associated to synthetic cannabinoids use. European review for medical and pharmacological sciences. vol 21. issue 1 Suppl. 2017-07-26. PMID:28379600. |
increasingly popular as substances of abuse since the 2000s, scs were produced initially to bind and study cannabinoid receptors (they also can be called synthetic cannabimimetics) failing in eliminating the psychoactive effects. |
2017-07-26 |
2023-08-13 |
Not clear |
| Nadine Schaefer, Andreas G Helfer, Mattias Kettner, Matthias W Laschke, Julia Schlote, Andreas H Ewald, Markus R Meyer, Michael D Menger, Hans H Maurer, Peter H Schmid. Metabolic patterns of JWH-210, RCS-4, and THC in pig urine elucidated using LC-HR-MS/MS: Do they reflect patterns in humans? Drug testing and analysis. vol 9. issue 4. 2017-07-18. PMID:27328899. |
the knowledge of pharmacokinetic (pk) properties of synthetic cannabinoids (scs) is important for interpretation of analytical results found for example in intoxicated individuals. |
2017-07-18 |
2023-08-13 |
human |
| Rahime Inci, Kiymet Handan Kelekci, Nihan Oguz, Semsettin Karaca, Baris Karadas, Adem Bayrakc. Dermatological aspects of synthetic cannabinoid addiction. Cutaneous and ocular toxicology. vol 36. issue 2. 2017-07-11. PMID:27028361. |
synthetic cannabinoids (scs) have recently become one of the most abused substances among young population and have caused severe health consequences in our country and worldwide. |
2017-07-11 |
2023-08-13 |
Not clear |
| L Sun, L Tai, Q Qiu, R Mitchell, S Fleetwood-Walker, E A Joosten, C W Cheun. Endocannabinoid activation of CB European journal of pain (London, England). vol 21. issue 5. 2017-05-30. PMID:28107590. |
endocannabinoid activation of cb spinal cord stimulation (scs) has been shown to be effective in the management of certain neuropathic pain conditions, however, the underlying mechanisms are incompletely understood. |
2017-05-30 |
2023-08-13 |
Not clear |
| X Diao, M A Huesti. Approaches, Challenges, and Advances in Metabolism of New Synthetic Cannabinoids and Identification of Optimal Urinary Marker Metabolites. Clinical pharmacology and therapeutics. vol 101. issue 2. 2017-05-29. PMID:27727455. |
we review approaches for determining metabolism of new synthetic cannabinoids (scs), and challenges and advances in identifying optimal urinary marker metabolites of sc intake. |
2017-05-29 |
2023-08-13 |
human |
| R Le Boisselier, J Alexandre, V Lelong-Boulouard, D Debruyn. Focus on cannabinoids and synthetic cannabinoids. Clinical pharmacology and therapeutics. vol 101. issue 2. 2017-05-29. PMID:27861784. |
the recent emergence of a multitude of synthetic cannabinoids (scs) has generated a wealth of new information, suggesting the usefulness of state-of-the-art on lato sensu cannabinoids. |
2017-05-29 |
2023-08-13 |
Not clear |
| R Le Boisselier, J Alexandre, V Lelong-Boulouard, D Debruyn. Focus on cannabinoids and synthetic cannabinoids. Clinical pharmacology and therapeutics. vol 101. issue 2. 2017-05-29. PMID:27861784. |
scs desired and adverse effects are considered to be more intense than those observed with cannabis smoking, which is partly explained by the full agonist activity and higher affinity for cannabinoid receptors. |
2017-05-29 |
2023-08-13 |
Not clear |
| R Le Boisselier, J Alexandre, V Lelong-Boulouard, D Debruyn. Focus on cannabinoids and synthetic cannabinoids. Clinical pharmacology and therapeutics. vol 101. issue 2. 2017-05-29. PMID:27861784. |
neurological and cardiovascular side effects observed after cannabinoid poisoning generally respond to conventional supportive care, but severe outcomes may occur in a minority of cases, mainly observed with scs. |
2017-05-29 |
2023-08-13 |
Not clear |
| R Le Boisselier, J Alexandre, V Lelong-Boulouard, D Debruyn. Focus on cannabinoids and synthetic cannabinoids. Clinical pharmacology and therapeutics. vol 101. issue 2. 2017-05-29. PMID:27861784. |
the likelihood of severe abuse and addiction produced by scs are of concern for the scientific community also interested in the potential therapeutic value of cannabinoids. |
2017-05-29 |
2023-08-13 |
Not clear |
| T W Grim, A J Morales, M M Gonek, J L Wiley, B F Thomas, G W Endres, L J Sim-Selley, D E Selley, S S Negus, A H Lichtma. Stratification of Cannabinoid 1 Receptor (CB1R) Agonist Efficacy: Manipulation of CB1R Density through Use of Transgenic Mice Reveals Congruence between In Vivo and In Vitro Assays. The Journal of pharmacology and experimental therapeutics. vol 359. issue 2. 2017-05-26. PMID:27535976. |
synthetic cannabinoids (scs) are an emerging class of abused drugs that differ from each other and the phytocannabinoid ∆ |
2017-05-26 |
2023-08-13 |
mouse |