| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Belal Haschimi, Katharina Elisabeth Grafinger, Benedikt Pulver, Evangelia Psychou, Sebastian Halter, Laura M Huppertz, Folker Westphal, Michael Pütz, Volker Auwärte. New synthetic cannabinoids carrying a cyclobutyl methyl side chain: Human Phase I metabolism and data on human cannabinoid receptor 1 binding and activation of Cumyl-CBMICA and Cumyl-CBMINACA. Drug testing and analysis. vol 13. issue 8. 2021-08-18. PMID:33788409. |
synthetic cannabinoids (scs) represent a large group of new psychoactive substances (nps), sustaining a high prevalence on the drug market since their first detection in 2008. |
2021-08-18 |
2023-08-13 |
human |
| Piotr Adamowic. Blood concentrations of synthetic cannabinoids. Clinical toxicology (Philadelphia, Pa.). vol 59. issue 3. 2021-08-17. PMID:32615814. |
synthetic cannabinoids (scs) are the largest and most diverse group of new psychoactive substances. |
2021-08-17 |
2023-08-13 |
Not clear |
| Laith Al-Eitan, Ahmed Alhusban, Saif Alahma. Effects of the synthetic cannabinoid XLR-11 on the viability and migration rates of human brain microvascular endothelial cells in a clinically-relevant model. Pharmacological reports : PR. vol 72. issue 6. 2021-08-12. PMID:32632915. |
synthetic cannabinoids (scs) are a group of newly-developed drugs that bind and activate endocannabinoid system receptors. |
2021-08-12 |
2023-08-13 |
human |
| Eef L Theunissen, Johannes T Reckweg, Nadia R P W Hutten, Kim P C Kuypers, Stefan W Toennes, Merja A Neukamm, Sebastian Halter, Johannes G Ramaeker. Intoxication by a synthetic cannabinoid (JWH-018) causes cognitive and psychomotor impairment in recreational cannabis users. Pharmacology, biochemistry, and behavior. vol 202. 2021-08-10. PMID:33497715. |
smoking mixtures containing synthetic cannabinoids (scs) have become very popular over the last years but pose a serious risk for public health. |
2021-08-10 |
2023-08-13 |
human |
| Aliesha Griffin, Mana Anvar, Kyla Hamling, Scott C Baraba. Phenotype-Based Screening of Synthetic Cannabinoids in a Dravet Syndrome Zebrafish Model. Frontiers in pharmacology. vol 11. 2021-07-24. PMID:32390835. |
identified scs with anti-seizure activity, in both assays, included five scs structurally classified as indole-based cannabinoids jwh 018 n-(5-chloropentyl) analog, jwh 018 n-(2-methylbutyl) isomer, 5-fluoro pb-22 5-hydroxyisoquinoline isomer, 5-fluoro adbica, and ab-fubinaca 3-fluorobenzyl isomer. |
2021-07-24 |
2023-08-13 |
zebrafish |
| Vera L Alves, João L Gonçalves, Joselin Aguiar, Maria J Caldeira, Helena M Teixeira, José S Câmar. Highly sensitive screening and analytical characterization of synthetic cannabinoids in nine different herbal mixtures. Analytical and bioanalytical chemistry. vol 413. issue 8. 2021-07-14. PMID:33575815. |
among them, synthetic cannabinoids (scs) represent the largest, most diversified and fastest growing group. |
2021-07-14 |
2023-08-13 |
Not clear |
| Melissa Hobbs, Rashmi Patel, Paul D Morrison, Nicola Kalk, James M Ston. Synthetic cannabinoid use in psychiatric patients and relationship to hospitalisation: A retrospective electronic case register study. Journal of psychopharmacology (Oxford, England). vol 34. issue 6. 2021-07-08. PMID:32108548. |
synthetic cannabinoids (scs) have been suggested to pose an even greater risk to mental health, but the effect on clinical outcome has not been directly measured. |
2021-07-08 |
2023-08-13 |
Not clear |
| Orapan Apirakkan, Ivana Gavrilović, David A Cowan, Vincenzo Abbat. In Vitro Phase I Metabolic Profiling of the Synthetic Cannabinoids AM-694, 5F-NNEI, FUB-APINACA, MFUBINAC, and AMB-FUBINACA. Chemical research in toxicology. vol 33. issue 7. 2021-07-01. PMID:32301604. |
synthetic cannabinoids (scs) constitute one of the most rapidly expanding class of new psychoactive substances. |
2021-07-01 |
2023-08-13 |
human |
| Hideaki Yano, Pramisha Adhikari, Sett Naing, Alexander F Hoffman, Michael H Baumann, Carl R Lupica, Lei Sh. Positive Allosteric Modulation of the 5-HT ACS chemical neuroscience. vol 11. issue 10. 2021-06-18. PMID:32324370. |
positive allosteric modulation of the 5-ht the nonmedical (i.e., recreational) misuse of synthetic cannabinoids (scs) is a worldwide public health problem. |
2021-06-18 |
2023-08-13 |
Not clear |
| b' Nunzia La Maida, Esther Papaseit, Lucia Mart\\xc3\\xadnez, Clara P\\xc3\\xa9rez-Ma\\xc3\\xb1\\xc3\\xa1, Lourdes Poyatos, Manuela Pellegrini, Simona Pichini, Roberta Pacifici, Mireia Ventura, Liliana Galindo, Francesco Paolo Busard\\xc3\\xb2, Mag\\xc3\\xad Farr\\xc3\\xa. Acute Pharmacological Effects and Oral Fluid Biomarkers of the Synthetic Cannabinoid UR-144 and THC in Recreational Users. Biology. vol 10. issue 4. 2021-05-15. PMID:33805054.' |
synthetic cannabinoids (scs) are one of the most frequent classes of new psychoactive substances monitored by the eu early warning system and world health organization. |
2021-05-15 |
2023-08-13 |
human |
| David Fabregat-Safont, María Ibáñez, Abel Baquero, Juan Vicente Sancho, Félix Hernández, Gonzalo Har. Investigation on the consumption of synthetic cannabinoids among teenagers by the analysis of herbal blends and urine samples. Journal of pharmaceutical and biomedical analysis. vol 186. 2021-05-04. PMID:32325401. |
the use of synthetic cannabinoids (scs), which escape conventional detection systems, may be a good alternative to elude routine drug analysis for cannabis. |
2021-05-04 |
2023-08-13 |
Not clear |
| E M Guler, M Y Bektay, A G Akyildiz, B H Sisman, F V Izzettin, A Kocyigi. Investigation of DNA damage, oxidative stress, and inflammation in synthetic cannabinoid users. Human & experimental toxicology. vol 39. issue 11. 2021-04-22. PMID:32508150. |
the widespread use of synthetic cannabinoids (scs) among youth has become an important public health problem. |
2021-04-22 |
2023-08-13 |
Not clear |
| Shiyang Qin, Guobin Xin, Juanna Wei, Genye He, Zengping Yuan, Hua Liu, Xu Zhang, Yuanfeng Wang, Wen Fang Zhang, Jianghai L. Metabolic Profiles of 5F-MDMB-PICA in Human Urine, Serum, and Hair Samples Using LC-Q Exactive HF MS. Journal of analytical toxicology. 2021-04-16. PMID:33860792. |
in 2020, 5f-mdmb-pica (5f-mdmb-2201) was one of the most common synthetic cannabinoids (scs) identified in drugs seized by the beijing drug control agency and it was categorized as schedule ii by the united nations office on drugs and crime (unodc) in march 2020. |
2021-04-16 |
2023-08-13 |
human |
| Nunzia La Maida, Manuela Pellegrini, Esther Papaseit, Clara Pérez-Mañá, Lourdes Poyatos, Mireia Ventura, Liliana Galindo, Francesco Paolo Busardò, Simona Pichini, Magí Farré, Emilia Marche. Determination of the Synthetic Cannabinoids JWH-122, JWH-210, UR-144 in Oral Fluid of Consumers by GC-MS and Quantification of Parent Compounds and Metabolites by UHPLC-MS/MS. International journal of molecular sciences. vol 21. issue 24. 2021-03-04. PMID:33321929. |
the consumption of synthetic cannabinoids (scs) has significantly increased in the last decade and the analysis of scs and their metabolites in human specimens is gaining interest in clinical and forensic toxicology. |
2021-03-04 |
2023-08-13 |
human |
| Kenneth B Walsh, Haley K Anderse. Molecular Pharmacology of Synthetic Cannabinoids: Delineating CB1 Receptor-Mediated Cell Signaling. International journal of molecular sciences. vol 21. issue 17. 2021-02-22. PMID:32854313. |
synthetic cannabinoids (scs) are a class of new psychoactive substances (npss) that exhibit high affinity binding to the cannabinoid cb1 and cb2 receptors and display a pharmacological profile similar to the phytocannabinoid (-)- |
2021-02-22 |
2023-08-13 |
Not clear |
| João Alexandre, Rui Malheiro, Diana Dias da Silva, Helena Carmo, Félix Carvalho, João Pedro Silv. The Synthetic Cannabinoids THJ-2201 and 5F-PB22 Enhance In Vitro CB International journal of molecular sciences. vol 21. issue 17. 2021-02-17. PMID:32872617. |
the synthetic cannabinoids thj-2201 and 5f-pb22 enhance in vitro cb recreational use of synthetic cannabinoids (scs) before and during pregnancy poses a major public health risk, due to the potential onset of neurodevelopmental disorders in the offspring. |
2021-02-17 |
2023-08-13 |
Not clear |
| Anna Pinson, Azure L Yarbrough, John M Bush, Christian V Cabanlong, Amal Shoeib, Bailey K Jackson, Saki Fukuda, Jyoti Gogoi, William E Fantegrossi, Keith McCain, Paul L Prather, Ryoichi Fujiwara, Anna Radominska-Pandy. Metabolism, CB1 cannabinoid receptor binding and in vivo activity of synthetic cannabinoid 5F-AKB48: Implications for toxicity. Pharmacology, biochemistry, and behavior. vol 195. 2021-02-08. PMID:32413436. |
akb48 and its fluorinated derivative 5f-akb48 are synthetic cannabinoids (scs) which have caused hospitalizations and deaths in human users. |
2021-02-08 |
2023-08-13 |
mouse |
| Orapan Apirakkan, Simon Hudson, Lewis Couchman, David Cowan, Stephen Morley, Vincenzo Abbat. The First Reported Case of a Synthetic Cannabinoid Ethyl Ester Detected in a Postmortem Blood Toxicological Analysis. Journal of analytical toxicology. vol 44. issue 9. 2021-02-04. PMID:32369163. |
metabolites of synthetic cannabinoids (scs) are widely used as markers for identifying scs' intake. |
2021-02-04 |
2023-08-13 |
Not clear |
| Eef L Theunissen, Johannes T Reckweg, Nadia R P W Hutten, Kim P C Kuypers, Stefan W Toennes, Merja A Neukamm, Sebastian Halter, Johannes G Ramaeker. Psychotomimetic symptoms after a moderate dose of a synthetic cannabinoid (JWH-018): implications for psychosis. Psychopharmacology. 2021-01-27. PMID:33501595. |
synthetic cannabinoids (scs) are the largest class of novel psychoactive substances (nps) and are associated with an increased risk of overdosing and adverse events such as psychosis. |
2021-01-27 |
2023-08-13 |
Not clear |
| Tímea Körmöczi, Éva Sija, László Institóris, Éva M Kereszty, István Ilisz, Róbert Berkec. Analytical Methodologies for the Characterization and Analysis of the Parent Compound and Phase I Metabolites of 4F-MDMB-BICA in Human Microsome, Urine, and Blood Samples. Journal of analytical toxicology. 2021-01-06. PMID:33404059. |
4f-mdmb-bica is one of the most dangerous new illicit synthetic cannabinoids (scs) in 2020. |
2021-01-06 |
2023-08-13 |
human |