| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rosa A Bobadilla L, Víctor Pérez-Alvarez, Ismael Bracho Valdés, Pedro López-Sanche. Effect of pregnancy on the roles of nitric oxide and prostaglandins in 5-hydroxytryptamine-induced contractions in rat isolated thoracic and abdominal aorta. Clinical and experimental pharmacology & physiology. vol 32. issue 3. 2005-06-22. PMID:15743404. |
full concentration-response curves to 5-ht were obtained in isolated rings from the thoracic and abdominal portion of the aorta from pregnant and non-pregnant rats in the presence and absence of the no synthase (nos) inhibitor n(g)-nitro-l-arginine methyl ester (l-name; 10 micromol/l) or the pg synthesis inhibitor indomethacin (10 micromol/l). |
2005-06-22 |
2023-08-12 |
rat |
| J R Shingala, R Balarama. Antihypertensive effect of 5-HT1A agonist buspirone and 5-HT2B antagonists in experimentally induced hypertension in rats. Pharmacology. vol 73. issue 3. 2005-04-26. PMID:15539790. |
for in vitro studies a similar treatment schedule was followed as in vivo studies and a cumulative concentration response curve of 5-ht was recorded on isolated thoracic aorta. |
2005-04-26 |
2023-08-12 |
rat |
| Youichirou Ootsuka, William W Blessin. Activation of slowly conducting medullary raphe-spinal neurons, including serotonergic neurons, increases cutaneous sympathetic vasomotor discharge in rabbit. American journal of physiology. Regulatory, integrative and comparative physiology. vol 288. issue 4. 2005-04-15. PMID:15550616. |
applications of the 5-hydroxytryptamine (ht)(2a) antagonist trans-4-((3z)3-[(2-dimethylaminoethyl)oxyimino]-3-(2-fluorophenyl)propen-1-yl)-phenol, hemifumarate (sr-46349b, 80 microg/kg in 0.8 ml) to the cerebrospinal fluid above thoracic spinal cord (t1-t7), but not the lumbar spinal cord (l2-l4), reduced raphe-evoked increases in ear pinna sympathetic vasomotor discharge from 43 +/- 9 to 16 +/- 6% (p < 0.01, n = 8). |
2005-04-15 |
2023-08-12 |
rabbit |
| Stephen M Rogers, Thomas Matheson, Ken Sasaki, Keith Kendrick, Stephen J Simpson, Malcolm Burrow. Substantial changes in central nervous system neurotransmitters and neuromodulators accompany phase change in the locust. The Journal of experimental biology. vol 207. issue Pt 20. 2005-01-18. PMID:15339956. |
long-term gregarious and solitarious locust nymphs differed in 11 of the 13 substances analysed: eight increased in both the brain and thoracic nerve cord (including glutamate, gaba, dopamine and serotonin), whereas three decreased (acetylcholine, tyramine and citrulline). |
2005-01-18 |
2023-08-12 |
Not clear |
| Stephen M Rogers, Thomas Matheson, Ken Sasaki, Keith Kendrick, Stephen J Simpson, Malcolm Burrow. Substantial changes in central nervous system neurotransmitters and neuromodulators accompany phase change in the locust. The Journal of experimental biology. vol 207. issue Pt 20. 2005-01-18. PMID:15339956. |
serotonin in the thoracic ganglia, however, did not follow this trend, but showed a ninefold increase after a 4 h period of crowding. |
2005-01-18 |
2023-08-12 |
Not clear |
| Eric S Landry, Pierre A Guerti. Differential effects of 5-HT1 and 5-HT2 receptor agonists on hindlimb movements in paraplegic mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 28. issue 6. 2004-12-30. PMID:15380867. |
the effects induced by serotonergic (5-ht) agonists of the 5-ht1 and 5-ht2 subclasses were examined on hindlimb movement generation in adult mice completely spinal cord transected at the low thoracic level. |
2004-12-30 |
2023-08-12 |
mouse |
| Beatriz P Settembrini, Marcelo J Villa. Distribution of serotonin in the central nervous system of the blood-feeding heteropteran, Triatoma infestans (Heteroptera: Reduviidae). Journal of morphology. vol 260. issue 1. 2004-11-23. PMID:15052594. |
serotonin immunoreactive cell bodies and fibers were observed in the brain, subesophageal ganglion, and thoracic ganglia. |
2004-11-23 |
2023-08-12 |
Not clear |
| E S Garcia, P Azambuj. Lignoids in insects: chemical probes for the study of ecdysis, excretion and Trypanosoma cruzi-triatomine interactions. Toxicon : official journal of the International Society on Toxinology. vol 44. issue 4. 2004-11-01. PMID:15302525. |
experiments in vitro, using isolated malpighian tubules of r. prolixus, indicate that burchellin (i) decreases diuretic hormone levels in the hemolymph but not the amount of diuretic hormone stored in the thoracic ganglionic masses (including axons); (ii) reduces the volume of urine secreted by isolated malpighian tubules; and (iii) 5-ht therapy cannot overcome the effect of burchellin on the malpighian tubules. |
2004-11-01 |
2023-08-12 |
Not clear |
| María A Sosa, Nadja Spitzer, Donald H Edwards, Deborah J Bar. A crustacean serotonin receptor: cloning and distribution in the thoracic ganglia of crayfish and freshwater prawn. The Journal of comparative neurology. vol 473. issue 4. 2004-06-24. PMID:15116388. |
5-ht(1crust) immunoreactivity (5-ht(1crust)ir) was observed surrounding the somata of specific groups of neurons and as punctate staining within the neuropil in all thoracic ganglia of crayfish and prawn. |
2004-06-24 |
2023-08-12 |
lobster |
| M J Enguix, L Sánchez, M Villazón, J Brea, H Tristán, H J Caruncho, M I Cadavid, M I Loz. Differential regulation of rat peripheral 5-HT(2A) and 5-HT(2B) receptor systems: influence of drug treatment. Naunyn-Schmiedeberg's archives of pharmacology. vol 368. issue 2. 2004-06-23. PMID:12861437. |
the in vitro contractile response elicited by serotonin (5-ht, 10 micro m) in the rat gastric fundus (5-ht(2b) receptor system) was rapid and followed by a partial fade to a steady state, in contrast with the rat thoracic aorta response (5-ht(2a) receptor system), which was more stable, slower and sustained. |
2004-06-23 |
2023-08-12 |
rat |
| Alo C Basu, Edward A Kravit. Morphology and monoaminergic modulation of Crustacean Hyperglycemic Hormone-like immunoreactive neurons in the lobster nervous system. Journal of neurocytology. vol 32. issue 3. 2004-04-16. PMID:14724388. |
neurosecretory elements of the serotonin (5ht) and octopamine (oct) systems, implicated in postural control and aggression, terminate densely in the vicinity of the second thoracic root neurons. |
2004-04-16 |
2023-08-12 |
lobster |
| James D Moffatt, Thomas M Cock. Pharmacologically distinct intracellular calcium pools regulate tonic and oscillatory responses in porcine thoracic duct. Journal of cardiovascular pharmacology. vol 43. issue 1. 2004-04-13. PMID:14668572. |
the present study investigated the mechanisms by which the thromboxane a2 mimetic u46619 can elicit phasic and tonic contractions in the pig thoracic duct, whereas other agonists like 5-hydroxytryptamine (5-ht) produce tonic contractions only. |
2004-04-13 |
2023-08-12 |
Not clear |
| Anne-Lise Poirrier, Yves Nyssen, Felix Scholtes, Sylvie Multon, Charline Rinkin, Géraldine Weber, Delphine Bouhy, Gary Brook, Rachelle Franzen, Jean Schoene. Repetitive transcranial magnetic stimulation improves open field locomotor recovery after low but not high thoracic spinal cord compression-injury in adult rats. Journal of neuroscience research. vol 75. issue 2. 2004-03-12. PMID:14705146. |
we propose that low thoracic lesions produce a greater functional deficit because they interfere with the locomotor centre and that rtms is beneficial in such lesions because it activates this central pattern generator, presumably via descending serotonin pathways. |
2004-03-12 |
2023-08-12 |
human |
| M Antri, D Orsal, J-Y Barth. Locomotor recovery in the chronic spinal rat: effects of long-term treatment with a 5-HT2 agonist. The European journal of neuroscience. vol 16. issue 3. 2002-11-08. PMID:12193190. |
a complete transection of the spinal cord at a low thoracic level induces a paraplegic syndrome that is accompanied by a loss of spinal cord serotonin content. |
2002-11-08 |
2023-08-12 |
rat |
| A H Chester, M Amrani, C A Sproson, M H Yacou. Interaction between thromboxane A2 and 5-hydroxytryptamine in the radial artery compared to the internal thoracic artery. General pharmacology. vol 35. issue 2. 2001-12-14. PMID:11707315. |
interaction between thromboxane a2 and 5-hydroxytryptamine in the radial artery compared to the internal thoracic artery. |
2001-12-14 |
2023-08-12 |
human |
| R Yoshio, T Taniguchi, H Itoh, I Muramats. Affinity of serotonin receptor antagonists and agonists to recombinant and native alpha1-adrenoceptor subtypes. Japanese journal of pharmacology. vol 86. issue 2. 2001-12-07. PMID:11459121. |
binding affinities of serotonin (5-ht)-receptor antagonists and agonists at human recombinant alpha1-adrenoceptor subtypes (alpha1a-, alpha1b- and alpha1d-subtypes) were examined and compared with the functional affinities obtained in rat caudal artery (alpha1a-subtype), dog carotid artery (alpha1b-subtype) and rat thoracic aorta (alpha1d-subtype). |
2001-12-07 |
2023-08-12 |
human |
| S Ito, T Ohta, Y Kasai, K Yonekubo, Y Nakazat. Heterogeneity of neuronal nicotinic acetylcholine receptors in 5-HT-containing chemoreceptor cells of the chicken aorta. British journal of pharmacology. vol 132. issue 8. 2001-07-19. PMID:11309266. |
ach, nicotine and dmpp caused concentration-dependent increases in 5-ht output from the thoracic aorta which effect was blocked by hexamethonium (0.1 mm). |
2001-07-19 |
2023-08-12 |
chicken |
| E S Garcia, M M Cabral, G A Schaub, O R Gottlieb, P Azambuj. Effects of lignoids on a hematophagous bug, Rhodnius prolixus: feeding, ecdysis and diuresis. Phytochemistry. vol 55. issue 6. 2001-03-01. PMID:11130672. |
in experiments in vitro, using isolated malpighian tubules, (i) burchellin reduced diuretic hormone levels in the hemolymph but not the amount of diuretic hormone stored in the thoracic ganglionic masses (including axons), (ii) burchellin decreased the volume of urine secreted by isolated malpighian tubules, and (iii) 5-ht could not overcome the effect of burchellin upon the malpighian tubules. |
2001-03-01 |
2023-08-12 |
Not clear |
| b' M G Cinar, S Ulker, G Alper, A Evin\\xc3\\xa. Effect of dietary vitamin E supplementation on vascular reactivity of thoracic aorta in streptozotocin-diabetic rats. Pharmacology. vol 62. issue 1. 2001-02-15. PMID:11150923.' |
after 12 weeks of treatment, thoracic aortic rings of rats were mounted in organ baths and contractile responses to phenylephrine and 5-hydroxytryptamine and relaxant responses to acetylcholine, calcium ionophore and sodium nitroprusside were assessed. |
2001-02-15 |
2023-08-12 |
rat |
| M M Cabral, A H Kollien, T Kleffmann, P Azambuja, O R Gottlieb, E S Garcia, G A Schau. Rhodnius prolixus: effects of the neolignan burchellin on in vivo and in vitro diuresis. Parasitology research. vol 86. issue 9. 2001-02-08. PMID:11002977. |
regardless of whether malpighian tubules originating from unfed, untreated or fed, burchellin-treated bugs were incubated in vitro in the hemolymph of these bugs or in physiological saline supplemented with 5-ht with or without burchellin or in homogenates of thoracic ganglionic masses of untreated and treated bugs, burchellin was consistently found to affect the secretion rates. |
2001-02-08 |
2023-08-12 |
Not clear |