| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Braak, E Braa. [Morphological changes in the human cerebral cortex in dementia]. Journal fur Hirnforschung. vol 32. issue 3. 1992-03-09. PMID:1779131. |
in fully developed alzheimer's disease, both the hippocampal formation and isocortical association areas are severely involved while the brunt of the pathology is found in the entorhinal region. |
1992-03-09 |
2023-08-11 |
human |
| K Jellinger, H Braak, E Braak, P Fische. Alzheimer lesions in the entorhinal region and isocortex in Parkinson's and Alzheimer's diseases. Annals of the New York Academy of Sciences. vol 640. 1992-02-28. PMID:1776740. |
alzheimer lesions in the entorhinal region and isocortex in parkinson's and alzheimer's diseases. |
1992-02-28 |
2023-08-11 |
human |
| K Jellinger, H Braak, E Braak, P Fische. Alzheimer lesions in the entorhinal region and isocortex in Parkinson's and Alzheimer's diseases. Annals of the New York Academy of Sciences. vol 640. 1992-02-28. PMID:1776740. |
in down's syndrome, alzheimer's disease, and parkinson's disease, early neuronal degeneration with deposition of nt and nft may selectively involve layer pre-alpha (ii) of the entorhinal region (brodmann 26 area) forming the origin of the glutamatergic perforant pathway. |
1992-02-28 |
2023-08-11 |
human |
| L A Hansen, E Masliah, S Quijada-Fawcett, D Rexi. Entorhinal neurofibrillary tangles in Alzheimer disease with Lewy bodies. Neuroscience letters. vol 129. issue 2. 1992-01-14. PMID:1745407. |
entorhinal neurofibrillary tangles in alzheimer disease with lewy bodies. |
1992-01-14 |
2023-08-11 |
Not clear |
| R Nitsch, M Frotsche. Maintenance of peripheral dendrites of GABAergic neurons requires specific input. Brain research. vol 554. issue 1-2. 1991-12-26. PMID:1933311. |
persisting transneuronal changes in gabaergic hippocampal neurons following the removal of their entorhinal afferents may play a role in alzheimer's disease since there is a severe degeneration of the entorhino-hippocampal projection in this neurodegenerative disorder. |
1991-12-26 |
2023-08-11 |
Not clear |
| J W Geddes, M C Wilson, F D Miller, C W Cotma. Molecular markers of reactive plasticity. Advances in experimental medicine and biology. vol 268. 1991-04-15. PMID:2075860. |
the expression of t alpha 1 mrna was increased in the rat hippocampal neurons following entorhinal lesions, and in the human hippocampus in patients with alzheimer's disease. |
1991-04-15 |
2023-08-11 |
human |
| L D Loopuijt, J B Seben. Loss of dopamine receptors in the olfactory bulb of patients with Alzheimer's disease. Brain research. vol 529. issue 1-2. 1991-03-19. PMID:1980844. |
since mitral cells are projection neurons with targets in the entorhinal and piriform cortex, the observation of loss of these cells supports the hypothesis of early involvement of the olfactory system in alzheimer's disease and the spread from the olfactory mucosa and bulb to the cerebral cortex and hippocampus via degeneration of interconnecting neurons. |
1991-03-19 |
2023-08-11 |
Not clear |
| C W Cotman, J W Geddes, J S Kahl. Axon sprouting in the rodent and Alzheimer's disease brain: a reactivation of developmental mechanisms? Progress in brain research. vol 83. 1990-09-28. PMID:2203106. |
the re-expression of the fetal form of alpha-tubulin mrna in rat after entorhinal lesions was found to be similar to the re-expression of the human fetal form of alpha-tubulin in alzheimer's brain. |
1990-09-28 |
2023-08-11 |
human |
| G S Zubenko, J Moossy, D Claassen, A J Martinez, G R Ra. Brain regional analysis of NADH-cytochrome C reductase activity in Alzheimer's disease. Journal of neuropathology and experimental neurology. vol 49. issue 3. 1990-06-11. PMID:2335781. |
the specific activity of antimycin a-insensitive nicotinamide adenine dinucleotide (nadh)-dependent cytochrome c reductase, an enzyme associated with endoplasmic reticulum, was determined in the superior temporal, entorhinal, and cerebellar cortex of 16 patients who died with alzheimer's disease and eight nondemented controls. |
1990-06-11 |
2023-08-11 |
Not clear |
| J W Geddes, K J Anderson, C W Cotma. Senile plaques as aberrant sprout-stimulating structures. Experimental neurology. vol 94. issue 3. 1987-01-21. PMID:3780919. |
in alzheimer's disease, the cholinergic septal input to the dentate gyrus molecular layer appears to sprout, presumably in response to the loss of entorhinal input to this region. |
1987-01-21 |
2023-08-11 |
Not clear |