| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J A P van de Nes, D Sandmann-Keil, H Braa. Interstitial cells subjacent to the entorhinal region expressing somatostatin-28 immunoreactivity are susceptible to development of Alzheimer's disease-related cytoskeletal changes. Acta neuropathologica. vol 104. issue 4. 2002-12-27. PMID:12200620. |
interstitial cells subjacent to the entorhinal region expressing somatostatin-28 immunoreactivity are susceptible to development of alzheimer's disease-related cytoskeletal changes. |
2002-12-27 |
2023-08-12 |
Not clear |
| J A P van de Nes, D Sandmann-Keil, H Braa. Interstitial cells subjacent to the entorhinal region expressing somatostatin-28 immunoreactivity are susceptible to development of Alzheimer's disease-related cytoskeletal changes. Acta neuropathologica. vol 104. issue 4. 2002-12-27. PMID:12200620. |
twenty-four cases selected for the absence, slight (braak stages i-ii), moderate (braak stages iii-iv), or serious degree (braak stages v-vi) of cortical neurofibrillary pathology were studied for the presence of alzheimer's disease-related abnormal tau in interstitial cells of the entorhinal region. |
2002-12-27 |
2023-08-12 |
Not clear |
| Isabelle Millien, Xavier Blaizot, Cyrille Giffard, Florence Mézenge, Ricardo Insausti, Jean-Claude Baron, Chantal Chavoi. Brain glucose hypometabolism after perirhinal lesions in baboons: implications for Alzheimer disease and aging. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 22. issue 10. 2002-11-05. PMID:12368664. |
the authors previously reported that excitotoxic lesions of both the perirhinal and entorhinal cortices in baboons induce remote neocortical and hippocampal hypometabolism reminiscent of that observed in alzheimer disease (ad), suggesting that disconnection may play a role in ad. |
2002-11-05 |
2023-08-12 |
Not clear |
| K M Bradley, V T O'Sullivan, N D W Soper, Z Nagy, E M-F King, A D Smith, B J Shepston. Cerebral perfusion SPET correlated with Braak pathological stage in Alzheimer's disease. Brain : a journal of neurology. vol 125. issue Pt 8. 2002-09-04. PMID:12135968. |
the 'braak stage' of the distribution of neurofibrillary pathology in post-mortem brains was used to classify spet scans taken in life from a mixed (dementia and control) elderly population into the entorhinal stage (n = 23 subjects), limbic stage (n = 30 subjects) and neocortical stage (n = 36 subjects) alzheimer's disease pathology. |
2002-09-04 |
2023-08-12 |
human |
| E Head, W Garzon-Rodriguez, J K Johnson, I T Lott, C W Cotman, C Glab. Oxidation of Abeta and plaque biogenesis in Alzheimer's disease and Down syndrome. Neurobiology of disease. vol 8. issue 5. 2002-01-23. PMID:11592849. |
we hypothesized that the distribution of oxidatively modified abeta, as determined by an affinity-purified antibody in the entorhinal and frontal cortices of alzheimer's disease (ad), down syndrome (ds), nondemented elderly control cases, and canine brain, would provide insight into the mechanisms of abeta accumulation. |
2002-01-23 |
2023-08-12 |
human |
| B C Dickerson, I Goncharova, M P Sullivan, C Forchetti, R S Wilson, D A Bennett, L A Beckett, L deToledo-Morrel. MRI-derived entorhinal and hippocampal atrophy in incipient and very mild Alzheimer's disease. Neurobiology of aging. vol 22. issue 5. 2002-01-03. PMID:11705634. |
mri-derived entorhinal and hippocampal atrophy in incipient and very mild alzheimer's disease. |
2002-01-03 |
2023-08-12 |
Not clear |
| P Gómez-Ramos, E J Mufson, M A Morá. Apolipoprotein E immunoreactivity in neurons and neurofibrillary degeneration of aged non-demented and Alzheimer's disease patients. Microscopy research and technique. vol 55. issue 1. 2001-12-04. PMID:11596149. |
to further analyze this relationship, hippocampal, entorhinal, temporopolar, and insular cortices of 10 non-demented and 7 alzheimer disease brains were studied with both light and electron microscopy. |
2001-12-04 |
2023-08-12 |
Not clear |
| T W Mitchell, J Nissanov, L Y Han, E J Mufson, J A Schneider, E J Cochran, D A Bennett, V M Lee, J Q Trojanowski, S E Arnol. Novel method to quantify neuropil threads in brains from elders with or without cognitive impairment. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 48. issue 12. 2001-01-18. PMID:11101631. |
we combined quantitative fractionation and image analysis to devise a strategy for measuring the burden of tau-rich nts in the entorhinal and perirhinal cortex of brains from elders with and without cognitive impairment, including dementia due to alzheimer's disease (ad). |
2001-01-18 |
2023-08-12 |
Not clear |
| H Braak, K Del Tredici, J Bohl, H Bratzke, E Braa. Pathological changes in the parahippocampal region in select non-Alzheimer's dementias. Annals of the New York Academy of Sciences. vol 911. 2000-08-09. PMID:10911877. |
in progressive neurodegenerative diseases, such as alzheimer's disease, argyrophilic grain disease, pick's disease, idiopathic parkinson syndrome, and huntington's disease, the transentorhinal and entorhinal regions are particularly susceptible to severe pathological changes. |
2000-08-09 |
2023-08-12 |
human |
| L de Toledo-Morrell, I Goncharova, B Dickerson, R S Wilson, D A Bennet. From healthy aging to early Alzheimer's disease: in vivo detection of entorhinal cortex atrophy. Annals of the New York Academy of Sciences. vol 911. 2000-08-09. PMID:10911878. |
in an attempt to determine the earliest sites of involvement in mild and incipient alzheimer's disease (ad), we compared entorhinal and hippocampal volume in (1) healthy elderly controls, (2) patients with very mild ad, and (3) elderly patients who were evaluated for cognitive complaints, but did not meet criteria for dementia. |
2000-08-09 |
2023-08-12 |
human |
| G W Van Hoesen, J C Augustinack, J Dierking, S J Redman, R Thangave. The parahippocampal gyrus in Alzheimer's disease. Clinical and preclinical neuroanatomical correlates. Annals of the New York Academy of Sciences. vol 911. 2000-08-09. PMID:10911879. |
the cortical areas that form the parahippocampal gyrus are vulnerable to pathological changes in alzheimer's disease (ad), and its entorhinal and perirhinal subdivisions are both the most heavily damaged cortical areas and the focus for disease onset. |
2000-08-09 |
2023-08-12 |
human |
| M B Graeber, S Kösel, E Grasbon-Frodl, H J Möller, P Mehraei. Histopathology and APOE genotype of the first Alzheimer disease patient, Auguste D. Neurogenetics. vol 1. issue 3. 2000-04-13. PMID:10737127. |
interestingly, alzheimer's histological preparations did not include the hippocampus or entorhinal region. |
2000-04-13 |
2023-08-12 |
Not clear |
| T Hayashi, H Fukuyama, Y Katsumi, T Hanakawa, Y Nagahama, H Yamauchi, H Tsukada, H Shibasak. Cerebral glucose metabolism in unilateral entorhinal cortex-lesioned rats: an animal PET study. Neuroreport. vol 10. issue 10. 1999-09-23. PMID:10424684. |
these findings suggest that entorhinal lesion induces cerebral cortical hypometabolism, which implies a pathogenetic role of entorhinal area on the cortical hypometabolism in alzheimer's disease. |
1999-09-23 |
2023-08-12 |
rat |
| M Kelliher, J Fastbom, R F Cowburn, W Bonkale, T G Ohm, R Ravid, V Sorrentino, C O'Neil. Alterations in the ryanodine receptor calcium release channel correlate with Alzheimer's disease neurofibrillary and beta-amyloid pathologies. Neuroscience. vol 92. issue 2. 1999-09-17. PMID:10408600. |
relationships between ryanodine receptor changes and the progression of alzheimer's disease pathology were determined by examining autoradiographic [3h]ryanodine binding in entorhinal cortex/anterior hippocampus sections from 22 cases that had been staged for neurofibrillary changes and beta-amyloid deposition. |
1999-09-17 |
2023-08-12 |
Not clear |
| M Mikkonen, I Alafuzoff, T Tapiola, H Soininen, R Miettine. Subfield- and layer-specific changes in parvalbumin, calretinin and calbindin-D28K immunoreactivity in the entorhinal cortex in Alzheimer's disease. Neuroscience. vol 92. issue 2. 1999-09-17. PMID:10408601. |
here, we examined neuropathological changes in the eight entorhinal subfields in post mortem alzheimer's disease subjects using thionin and bielschowsky stains and parvalbumin, calretinin and calbindin-d28k immunohistochemistry. |
1999-09-17 |
2023-08-12 |
human |
| M Mikkonen, I Alafuzoff, T Tapiola, H Soininen, R Miettine. Subfield- and layer-specific changes in parvalbumin, calretinin and calbindin-D28K immunoreactivity in the entorhinal cortex in Alzheimer's disease. Neuroscience. vol 92. issue 2. 1999-09-17. PMID:10408601. |
detailed analysis further revealed that non-principal cells containing parvalbumin or calbindin-d28k showed morphological alterations early in the entorhinal pathology of alzheimer's disease, whereas non-principal neurons containing calretinin were better preserved even in alzheimer's disease patients with severe entorhinal pathology. |
1999-09-17 |
2023-08-12 |
human |
| K Meguro, X Blaizot, Y Kondoh, C Le Mestric, J C Baron, C Chavoi. Neocortical and hippocampal glucose hypometabolism following neurotoxic lesions of the entorhinal and perirhinal cortices in the non-human primate as shown by PET. Implications for Alzheimer's disease. Brain : a journal of neurology. vol 122 ( Pt 8). 1999-09-07. PMID:10430835. |
in the entorhinal and perirhinal cortices) are three early characteristics of alzheimer's disease. |
1999-09-07 |
2023-08-12 |
Not clear |
| W L Bonkale, R F Cowburn, T G Ohm, N Bogdanovic, J Fastbo. A quantitative autoradiographic study of [3H]cAMP binding to cytosolic and particulate protein kinase A in post-mortem brain staged for Alzheimer's disease neurofibrillary changes and amyloid deposits. Brain research. vol 818. issue 2. 1999-05-06. PMID:10082824. |
autoradiographic [3h]camp binding to cytosolic and particulate pka was measured in sections of entorhinal cortex/hippocampal formation from 23 cases that had been staged for alzheimer's disease-related neurofibrillary changes and amyloid deposits according to braak and braak [h. braak, e. braak, neuropathological staging of alzheimer's-related changes, acta neuropathol. |
1999-05-06 |
2023-08-12 |
Not clear |
| T Kurumatani, J Fastbom, W L Bonkale, N Bogdanovic, B Winblad, T G Ohm, R F Cowbur. Loss of inositol 1,4,5-trisphosphate receptor sites and decreased PKC levels correlate with staging of Alzheimer's disease neurofibrillary pathology. Brain research. vol 796. issue 1-2. 1998-10-29. PMID:9689471. |
in the present study, we determined the autoradiographic localization of [3h]ip3 and [3h]ip4 binding to their calcium mobilizing receptor sites and [3h]phorbol 12,13-dibutyrate ([3h]pdbu) binding to pkc in sections of entorhinal cortex/hippocampal formation and cerebellum from 24 cases that had been staged for alzheimer's disease-related neurofibrillary changes and amyloid deposition according to braak and braak [acta neuropathol. |
1998-10-29 |
2023-08-12 |
Not clear |
| T Kurumatani, J Fastbom, W L Bonkale, N Bogdanovic, B Winblad, T G Ohm, R F Cowbur. Loss of inositol 1,4,5-trisphosphate receptor sites and decreased PKC levels correlate with staging of Alzheimer's disease neurofibrillary pathology. Brain research. vol 796. issue 1-2. 1998-10-29. PMID:9689471. |
these findings suggest that reduced ip3 receptor and pkc levels in the entorhinal cortex/hippocampal formation reflect and may be important for the progression of alzheimer's disease neurofibrillary pathology. |
1998-10-29 |
2023-08-12 |
Not clear |