| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| O J Vogels, K Renkawek, C A Broere, H J ter Laak, F van Worku. Galanin-like immunoreactivity within Ch2 neurons in the vertical limb of the diagonal band of Broca in aging and Alzheimer's disease. Acta neuropathologica. vol 78. issue 1. 1989-07-21. PMID:2472041. |
in the present study for the first time galanin immunoreactivity in the human ch2 region is morphologically investigated and related to the severity of hippocampal plaques and neurofibrillary tangles in alzheimer's disease. |
1989-07-21 |
2023-08-11 |
human |
| O J Vogels, K Renkawek, C A Broere, H J ter Laak, F van Worku. Galanin-like immunoreactivity within Ch2 neurons in the vertical limb of the diagonal band of Broca in aging and Alzheimer's disease. Acta neuropathologica. vol 78. issue 1. 1989-07-21. PMID:2472041. |
considering the cholinergic deficiency in alzheimer's disease as a secondary phenomenon to primary cortical and hippocampal lesions, and realizing the inhibitory effect of galanin upon acetylcholine release in hippocampus, this preliminary study suggests that a decreased galanin immunoreactivity in ch2 in alzheimer's disease, reflects a possible negative feedback mechanism to a degenerating cholinergic projection system. |
1989-07-21 |
2023-08-11 |
human |
| H J Gertz, G Schoknecht, H Krüger, J Cervos-Navarr. Stability of cell size and nucleolar size in tangle-bearing neurons of the hippocampus in Alzheimer's disease. Brain research. vol 487. issue 2. 1989-07-18. PMID:2731050. |
stability of cell size and nucleolar size in tangle-bearing neurons of the hippocampus in alzheimer's disease. |
1989-07-18 |
2023-08-11 |
Not clear |
| G S Zubenko, J Moossy, A J Martinez, G R Rao, U Kopp, I Hani. A brain regional analysis of morphologic and cholinergic abnormalities in Alzheimer's disease. Archives of neurology. vol 46. issue 6. 1989-07-07. PMID:2730375. |
in the brains of 21 patients with alzheimer's disease (ad) and 10 nondemented controls, senile plaques (sps), neurofibrillary tangles (nfts), and three indexes of cholinergic function were quantified in the middle frontal (mf) and superior temporal (st) cortex, the entorhinal cortex (hen), and the prosubiculum (hpr) of the hippocampus. |
1989-07-07 |
2023-08-11 |
Not clear |
| J Moossy, G S Zubenko, A J Martinez, G R Rao, U Kopp, I Hani. Lateralization of brain morphologic and cholinergic abnormalities in Alzheimer's disease. Archives of neurology. vol 46. issue 6. 1989-07-07. PMID:2730376. |
the extent of left-right asymmetry in the densities of senile plaques and neurofibrillary tangles and the levels of the cholinergic enzymes choline acetyltransferase and acetylcholinesterase were quantified in the middle frontal and superior temporal cerebral cortex, entorhinal cortex, and prosubiculum of the hippocampus from 21 patients who died with alzheimer's disease. |
1989-07-07 |
2023-08-11 |
Not clear |
| M B Lenders, M C Peers, G Tramu, A Delacourte, A Defossez, H Petit, M Mazzuc. Dystrophic peptidergic neurites in senile plaques of Alzheimer's disease hippocampus precede formation of paired helical filaments. Brain research. vol 481. issue 2. 1989-06-30. PMID:2497927. |
dystrophic peptidergic neurites in senile plaques of alzheimer's disease hippocampus precede formation of paired helical filaments. |
1989-06-30 |
2023-08-11 |
Not clear |
| R A Stern, L Otvos, J Q Trojanowski, V M Le. Monoclonal antibodies to a synthetic peptide homologous with the first 28 amino acids of Alzheimer's disease beta-protein recognize amyloid and diverse glial and neuronal cell types in the central nervous system. The American journal of pathology. vol 134. issue 5. 1989-06-20. PMID:2524164. |
using rabbit and mouse antisera, and 7 mabs, sections of neocortex, hippocampus, cerebellum, and spinal cord from alzheimer's disease (ad), down's syndrome (ds), and control cases were probed. |
1989-06-20 |
2023-08-11 |
mouse |
| M L Schmidt, V M Lee, J Q Trojanowsk. Analysis of epitopes shared by Hirano bodies and neurofilament proteins in normal and Alzheimer's disease hippocampus. Laboratory investigation; a journal of technical methods and pathology. vol 60. issue 4. 1989-06-02. PMID:2468822. |
analysis of epitopes shared by hirano bodies and neurofilament proteins in normal and alzheimer's disease hippocampus. |
1989-06-02 |
2023-08-11 |
human |
| N W Kowall, M F Bea. Galanin-like immunoreactivity is present in human substantia innominata and in senile plaques in Alzheimer's disease. Neuroscience letters. vol 98. issue 1. 1989-05-26. PMID:2469045. |
galanin-immunoreactive neurites were found in a small number of senile plaques in the hippocampus and temporal isocortex of alzheimer's disease patients. |
1989-05-26 |
2023-08-11 |
human |
| T Yamamoto, Y Iwasaki, Y Sato, H Yamamoto, H Konn. Astrocytic pathology of methionine sulfoximine-induced encephalopathy. Acta neuropathologica. vol 77. issue 4. 1989-05-26. PMID:2565645. |
prolonged mso-loading (every 12 h up to three times, 100-150 mg/kg body weight) brought about the appearance of astrocytes with swollen, watery nuclei reminiscent of alzheimer ii glia chiefly in the neocortex, hippocampus and lateral thalamus after 24 h. concomitantly, profound accumulation of glycogen ensued in the superficial three layers of the neocortex, hippocampus and pyriform cortex. |
1989-05-26 |
2023-08-11 |
rat |
| R M Zweig, K M Schegg, J H Peacock, D Melarke. A case of Alzheimer's disease and hippocampal sclerosis with normal cholinergic activity in basal forebrain, neocortex, and hippocampus. Neurology. vol 39. issue 2 Pt 1. 1989-03-23. PMID:2915803. |
a case of alzheimer's disease and hippocampal sclerosis with normal cholinergic activity in basal forebrain, neocortex, and hippocampus. |
1989-03-23 |
2023-08-11 |
Not clear |
| R M Zweig, K M Schegg, J H Peacock, D Melarke. A case of Alzheimer's disease and hippocampal sclerosis with normal cholinergic activity in basal forebrain, neocortex, and hippocampus. Neurology. vol 39. issue 2 Pt 1. 1989-03-23. PMID:2915803. |
despite hippocampal sclerosis, changes typical of alzheimer's disease were not found in this region or in basal forebrain. |
1989-03-23 |
2023-08-11 |
Not clear |
| A Represa, C Duyckaerts, E Tremblay, J J Hauw, Y Ben-Ar. Is senile dementia of the Alzheimer type associated with hippocampal plasticity? Brain research. vol 457. issue 2. 1989-03-22. PMID:2905920. |
is senile dementia of the alzheimer type associated with hippocampal plasticity? |
1989-03-22 |
2023-08-11 |
Not clear |
| A Represa, C Duyckaerts, E Tremblay, J J Hauw, Y Ben-Ar. Is senile dementia of the Alzheimer type associated with hippocampal plasticity? Brain research. vol 457. issue 2. 1989-03-22. PMID:2905920. |
the density of binding sites for excitatory amino acids in the hippocampus of sdat (senile dementia of the alzheimer type) patients has been investigated. |
1989-03-22 |
2023-08-11 |
Not clear |
| C F Höhmann, J T Coyl. Long-term effects of basal forebrain lesions on cholinergic, noradrenergic and serotonergic markers in mouse neocortex. Brain research bulletin. vol 21. issue 1. 1989-03-16. PMID:3219596. |
lesions of basal forebrain cholinergic neurons projecting to cerebral cortex and hippocampus have recently been exploited as animal models for some of the neurochemical and behavioral deficits of alzheimer's disease. |
1989-03-16 |
2023-08-11 |
mouse |
| M Poltorak, J R Stevens, W J Freed, M F Casanov. The expression of phosphorylated neurofilament epitopes in human brains. Brain research. vol 475. issue 2. 1989-02-28. PMID:2463857. |
the expression of phosphorylated neurofilaments (pnf) epitopes in hippocampal neurons was examined in 5 cases of alzheimer's disease and 12 brains of schizophrenic patients. |
1989-02-28 |
2023-08-11 |
human |
| R Cortés, A Probst, J M Palacio. Decreased densities of dopamine D1 receptors in the putamen and hippocampus in senile dementia of the Alzheimer type. Brain research. vol 475. issue 1. 1989-02-28. PMID:2975188. |
decreased densities of dopamine d1 receptors in the putamen and hippocampus in senile dementia of the alzheimer type. |
1989-02-28 |
2023-08-11 |
Not clear |
| J P Seab, W J Jagust, S T Wong, M S Roos, B R Reed, T F Budinge. Quantitative NMR measurements of hippocampal atrophy in Alzheimer's disease. Magnetic resonance in medicine. vol 8. issue 2. 1989-02-21. PMID:3210957. |
quantitative nmr measurements of hippocampal atrophy in alzheimer's disease. |
1989-02-21 |
2023-08-11 |
human |
| M M Mesulam, C Geul. Acetylcholinesterase-rich pyramidal neurons in the human neocortex and hippocampus: absence at birth, development during the life span, and dissolution in Alzheimer's disease. Annals of neurology. vol 24. issue 6. 1989-02-07. PMID:3207359. |
acetylcholinesterase-rich pyramidal neurons in the human neocortex and hippocampus: absence at birth, development during the life span, and dissolution in alzheimer's disease. |
1989-02-07 |
2023-08-11 |
human |
| R F Cowburn, J A Hardy, R S Briggs, P J Robert. Characterisation, density, and distribution of kainate receptors in normal and Alzheimer's diseased human brain. Journal of neurochemistry. vol 52. issue 1. 1989-01-25. PMID:2535708. |
no change in either the affinity or the number of kainate receptors was seen in any of the regions studied, despite the loss of neocortical and hippocampal glutamatergic terminals in the alzheimer's diseased brains, as previously reported. |
1989-01-25 |
2023-08-11 |
human |