All Relations between Alzheimer Disease and main olfactory bulb

Reference Sentence Publish Date Extraction Date Species
Zarui A Melikyan, Mar\\xc3\\xada M Corrada, Anne-Marie Leiby, Seyed Ahmad Sajjadi, Syed Bukhari, Thomas J Montine, Claudia H Kawa. Cognitive resilience to three dementia-related neuropathologies in an oldest-old man: A case report from The 90+ Study. Neurobiology of aging vol 116 issue 2022 35526514 neuropathological examination revealed intermediate level of alzheimer's disease neuropathologic change (thal phase 5, braak nft stage iv, cerad score 3), lewy bodies and neurites in the olfactory bulb, brainstem and limbic areas (braak pd stage 4), tdp-43 inclusions in the amygdala and hippocampus (late stage 2), and a microvascular lesion in putamen. 2022-05-08 2022-05-12 Not clear
Helen C Murray, Kory Johnson, Andrea Sedlock, Blake Highet, Birger Victor Dieriks, Praju Vikas Anekal, Richard L M Faull, Maurice A Curtis, Alan Koretsky, Dragan Mari. Lamina-specific immunohistochemical signatures in the olfactory bulb of healthy, Alzheimer's and Parkinson's disease patients. Communications biology vol 5 issue 1 2022 35075270 lamina-specific immunohistochemical signatures in the olfactory bulb of healthy, alzheimer's and parkinson's disease patients. 2022-01-25 2022-01-27 Not clear
Helen C Murray, Kory Johnson, Andrea Sedlock, Blake Highet, Birger Victor Dieriks, Praju Vikas Anekal, Richard L M Faull, Maurice A Curtis, Alan Koretsky, Dragan Mari. Lamina-specific immunohistochemical signatures in the olfactory bulb of healthy, Alzheimer's and Parkinson's disease patients. Communications biology vol 5 issue 1 2022 35075270 we demonstrate this approach by cumulatively screening up to 100 markers on formalin-fixed paraffin-embedded sections of human olfactory bulb sourced from neurologically normal (no significant pathology), alzheimer's (ad), and parkinson's disease (pd) patients. 2022-01-25 2022-01-27 Not clear
Shaymaa Rezk, Samah Lashen, Mohamed El-Adl, Gehad E Elshopakey, Mona M Elghareeb, Basma M Hendam, Thomas Caceci, Carlo Cenciarelli, Hany E Mare. Effects of Rosemary Oil (Rosmarinus officinalis) supplementation on the fate of the transplanted human olfactory bulb neural stem cells against ibotenic acid-induced neurotoxicity (Alzheimer model) in rat. Metabolic brain disease vol issue 2022 35075502 effects of rosemary oil (rosmarinus officinalis) supplementation on the fate of the transplanted human olfactory bulb neural stem cells against ibotenic acid-induced neurotoxicity (alzheimer model) in rat. 2022-01-25 2022-01-27 Not clear
J Kendall Berry, Daniel Co. Increased oscillatory power in a computational model of the olfactory bulb due to synaptic degeneration. Physical review. E vol 104 issue 2-1 2021 34525666 we thus demonstrate one potential mechanism involved in the increased gamma oscillations seen in some animal models of alzheimer's disease, and we highlight the potential that pathological olfactory bulb behavior presents as an early biomarker of disease. 2021-12-10 2022-01-13 Not clear
Melania Gonzalez-Rodriguez, Veronica Astillero-Lopez, Patricia Villanueva-Anguita, M Eugenia Paya-Rodriguez, Alicia Flores-Cuadrado, Sandra Villar-Conde, Isabel Ubeda-Banon, Alino Martinez-Marcos, Daniel Saiz-Sanche. Somatostatin and Astroglial Involvement in the Human Limbic System in Alzheimer's Disease. International journal of molecular sciences vol 22 issue 16 2021 34445147 altogether, we can conclude that somatostatin expression is highly reduced in the human hippocampus, but not the olfactory bulb, and may play a role in alzheimer's disease pathogenesis. 2021-09-15 2022-01-13 Not clear
Mercedes Lach\\xc3\\xa9n-Montes, Ignacio \\xc3\\x8d\\xc3\\xb1igo-Marco, Paz Cartas-Cejudo, Joaqu\\xc3\\xadn Fern\\xc3\\xa1ndez-Irigoyen, Enrique Santamar\\xc3\\xad. Olfactory Bulb Proteomics Reveals Widespread Proteostatic Disturbances in Mixed Dementia and Guides for Potential Serum Biomarkers to Discriminate Alzheimer Disease and Mixed Dementia Phenotypes. Journal of personalized medicine vol 11 issue 6 2021 34204996 olfactory bulb proteomics reveals widespread proteostatic disturbances in mixed dementia and guides for potential serum biomarkers to discriminate alzheimer disease and mixed dementia phenotypes. 2021-07-05 2022-01-13 Not clear
Helen C Murray, Birger Victor Dieriks, Molly E V Swanson, Praju Vikas Anekal, Clinton Turner, Richard L M Faull, Leonardo Belluscio, Alan Koretsky, Maurice A Curti. The unfolded protein response is activated in the olfactory system in Alzheimer's disease. Acta neuropathologica communications vol 8 issue 1 2021 32665027 olfactory dysfunction is an early and prevalent symptom of alzheimer's disease (ad) and the olfactory bulb is a nexus of beta-amyloid plaque and tau neurofibrillary tangle (nft) pathology during early ad progression. 2021-05-31 2022-01-13 Not clear
Mercedes Lachen-Montes, Andrea Gonz\\xc3\\xa1lez-Morales, Maialen Palomino, Karina Ausin, Marta G\\xc3\\xb3mez-Ochoa, Mar\\xc3\\xada Victoria Zelaya, Isidro Ferrer, Alberto P\\xc3\\xa9rez-Mediavilla, Joaqu\\xc3\\xadn Fern\\xc3\\xa1ndez-Irigoyen, Enrique Santamar\\xc3\\xad. Early-Onset Molecular Derangements in the Olfactory Bulb of Tg2576 Mice: Novel Insights Into the Stress-Responsive Olfactory Kinase Dynamics in Alzheimer's Disease. Frontiers in aging neuroscience vol 11 issue 2020 31244650 early-onset molecular derangements in the olfactory bulb of tg2576 mice: novel insights into the stress-responsive olfactory kinase dynamics in alzheimer's disease. 2020-10-01 2022-01-13 Not clear
Patrick Delafontaine-Martel, Joel Lefebvre, Pier-Luc Tardif, Bernard I L\\xc3\\xa9vy, Philippe Pouliot, Fr\\xc3\\xa9d\\xc3\\xa9ric Lesag. Whole brain vascular imaging in a mouse model of Alzheimer's disease with two-photon microscopy. Journal of biomedical optics vol 23 issue 7 2019 29998647 focusing on the medial prefrontal cortex, cerebral cortex, the olfactory bulb, and the hippocampal formation, we compared the vd of three age groups (2-, 4.5-, and 8-months-old), for both wild type mice and a transgenic model (app/ps1) with pathology resembling alzheimer's disease (ad). 2019-12-16 2022-01-13 Not clear
Rui Zheng, Zhong-Hao Zhang, Yu-Xi Zhao, Chen Chen, Shi-Zheng Jia, Xian-Chun Cao, Li-Ming Shen, Jia-Zuan Ni, Guo-Li Son. Transcriptomic Insights into the Response of the Olfactory Bulb to Selenium Treatment in a Mouse Model of Alzheimer's Disease. International journal of molecular sciences vol 20 issue 12 2019 31248178 transcriptomic insights into the response of the olfactory bulb to selenium treatment in a mouse model of alzheimer's disease. 2019-12-10 2022-01-13 Not clear
Zhong-Hao Zhang, Chen Chen, Qiu-Yan Wu, Rui Zheng, Yao Chen, Qiong Liu, Jia-Zuan Ni, Guo-Li Son. Selenomethionine Ameliorates Neuropathology in the Olfactory Bulb of a Triple Transgenic Mouse Model of Alzheimer's Disease. International journal of molecular sciences vol 17 issue 10 2019 27689994 selenomethionine ameliorates neuropathology in the olfactory bulb of a triple transgenic mouse model of alzheimer's disease. 2019-11-20 2022-01-12 Not clear
Mercedes Lach\\xc3\\xa9n-Montes, Andrea Gonz\\xc3\\xa1lez-Morales, Mar\\xc3\\xada Victoria Zelaya, Estela P\\xc3\\xa9rez-Valderrama, Karina Aus\\xc3\\xadn, Isidro Ferrer, Joaqu\\xc3\\xadn Fern\\xc3\\xa1ndez-Irigoyen, Enrique Santamar\\xc3\\xad. Olfactory bulb neuroproteomics reveals a chronological perturbation of survival routes and a disruption of prohibitin complex during Alzheimer's disease progression. Scientific reports vol 7 issue 1 2019 28831118 olfactory bulb neuroproteomics reveals a chronological perturbation of survival routes and a disruption of prohibitin complex during alzheimer's disease progression. 2019-04-03 2022-01-13 Not clear
K A Josephs, D W Dickso. TDP-43 in the olfactory bulb in Alzheimer's disease. Neuropathology and applied neurobiology vol 42 issue 4 2018 26810591 tdp-43 in the olfactory bulb in alzheimer's disease. 2018-02-12 2022-01-12 Not clear
Stefan J Kempf, Athanasios Metaxas, Mar\\xc3\\xada Ib\\xc3\\xa1\\xc3\\xb1ez-Vea, Sultan Darvesh, Bente Finsen, Martin R Larse. An integrated proteomics approach shows synaptic plasticity changes in an APP/PS1 Alzheimer's mouse model. Oncotarget vol 7 issue 23 2018 27144524 the aim of this study was to elucidate the molecular signature of alzheimer's disease-associated amyloid pathology.we used the double appswe/ps1\xce\x94e9 mouse, a widely used model of cerebral amyloidosis, to compare changes in proteome, including global phosphorylation and sialylated n-linked glycosylation patterns, pathway-focused transcriptome and neurological disease-associated mirnaome with age-matched controls in neocortex, hippocampus, olfactory bulb and brainstem. 2018-01-17 2022-01-12 Not clear
Mercedes Lach\\xc3\\xa9n-Montes, Andrea Gonz\\xc3\\xa1lez-Morales, Xabier Mart\\xc3\\xadnez de Morentin, Estela P\\xc3\\xa9rez-Valderrama, Karina Aus\\xc3\\xadn, Mar\\xc3\\xada Victoria Zelaya, Antonio Serna, Ester Aso, Isidro Ferrer, Joaqu\\xc3\\xadn Fern\\xc3\\xa1ndez-Irigoyen, Enrique Santamar\\xc3\\xad. An early dysregulation of FAK and MEK/ERK signaling pathways precedes the \\xce\\xb2-amyloid deposition in the olfactory bulb of APP/PS1 mouse model of Alzheimer's disease. Journal of proteomics vol 148 issue 2017 27498392 an early dysregulation of fak and mek/erk signaling pathways precedes the \xce\xb2-amyloid deposition in the olfactory bulb of app/ps1 mouse model of alzheimer's disease. 2017-11-27 2022-01-12 Not clear
Emrin Horgusluoglu, Kelly Nudelman, Kwangsik Nho, Andrew J Sayki. Adult neurogenesis and neurodegenerative diseases: A systems biology perspective. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics vol 174 issue 1 2017 26879907 new neurons are generated throughout adulthood in two regions of the brain, the olfactory bulb and dentate gyrus of the hippocampus, and are incorporated into the hippocampal network circuitry; disruption of this process has been postulated to contribute to neurodegenerative diseases including alzheimer's disease and parkinson's disease. 2017-08-21 2022-01-12 Not clear
Gabrielle F Ruggiero, Jeannette Y Wic. Olfaction: New Understandings, Diagnostic Applications. The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists vol 31 issue 11 2017 28107119 it's also an initial symptom of alzheimer's dementia (ad); the amyloid plaques and tangles characterizing ad invade the olfactory bulb and hippocampus early in its course, hampering odor identification. 2017-06-06 2022-01-13 Not clear
Magdalena Misiak, Rebeca Vergara Greeno, Beverly A Baptiste, Peter Sykora, Dong Liu, Stephanie Cordonnier, Evandro F Fang, Deborah L Croteau, Mark P Mattson, Vilhelm A Boh. DNA polymerase \\xce\\xb2 decrement triggers death of olfactory bulb cells and impairs olfaction in a mouse model of Alzheimer's disease. Aging cell vol 16 issue 1 2017 27686631 dna polymerase \xce\xb2 decrement triggers death of olfactory bulb cells and impairs olfaction in a mouse model of alzheimer's disease. 2017-06-05 2022-01-12 Not clear
\\xc3\\x96 Yaldizli, I-K Penner, T Yonekawa, Y Naegelin, J Kuhle, M Pardini, D T Chard, C Stippich, J-I Kira, K Bendfeldt, M Amann, E-W Radue, L Kappos, T Sprenge. The association between olfactory bulb volume, cognitive dysfunction, physical disability and depression in multiple sclerosis. European journal of neurology vol 23 issue 3 2016 26699999 olfactory bulb atrophy is associated with cognitive dysfunction in parkinson's and alzheimer's disease, and with major depression. 2016-12-13 2022-01-12 Not clear
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