All Relations between Alzheimer Disease and main olfactory bulb

Publication Sentence Publish Date Extraction Date Species
Xiang Zhou, Kangning Dong, Shihua Zhan. Integrating spatial transcriptomics data across different conditions, technologies and developmental stages. Nature computational science. vol 3. issue 10. 2024-01-04. PMID:38177758. we apply staligner to st datasets of the human cortex slices from different samples, the mouse olfactory bulb slices generated by two profiling technologies, the mouse hippocampus tissue slices under normal and alzheimer's disease conditions, and the spatiotemporal atlases of mouse organogenesis. 2024-01-04 2024-01-07 mouse
Aron S Buchman, Sue E Leurgans, Namhee Kim, Sonal Agrawal, Shahram Oveisgharan, Andrea R Zammit, Veronique VanderHorst, Sukrit Nag, David A Bennet. Alzheimer's Disease Pathology Outside of the Cerebrum Is Related to a Higher Odds of Dementia. Journal of Alzheimer's disease : JAD. 2023-10-16. PMID:37840485. assessments of alzheimer's disease pathology do not routinely include lower brainstem, olfactory bulb, and spinal cord. 2023-10-16 2023-11-08 Not clear
Shaymaa Rezk, Samah Lashen, Mohamed El-Adl, Gehad E Elshopakey, Mona M Elghareeb, Basma M Hendam, Thomas Caceci, Carlo Cenciarelli, Hany E Mare. Retraction Note: Effects of Rosemary Oil (Rosmarinus officinalis) supplementation on the fate of the transplanted human olfactory bulb neural stem cells against ibotenic acid-induced neurotoxicity (Alzheimer model) in rat. Metabolic brain disease. 2023-08-29. PMID:37642898. retraction note: effects of rosemary oil (rosmarinus officinalis) supplementation on the fate of the transplanted human olfactory bulb neural stem cells against ibotenic acid-induced neurotoxicity (alzheimer model) in rat. 2023-08-29 2023-09-07 human
Golam M I Chowdhury, Kevin L Behar, Graeme F Mason, Douglas L Rothman, Robin A de Graa. Measurement of Neuro-energetics and Neurotransmission in the Rat Olfactory Bulb by NMR in biomedicine. 2023-04-23. PMID:37088548. measurement of neuro-energetics and neurotransmission in the rat olfactory bulb by the olfactory bulb (ob) plays a fundamental role in the sense of smell and has been implicated in several pathologies, including alzheimer's disease. 2023-04-23 2023-08-14 rat
Sarah Carnemolla, Fiona Kumfor, Cheng Tao Liang, David Foxe, Rebekah Ahmed, Olivier Pigue. Olfactory Bulb Integrity in Frontotemporal Dementia and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2022-07-18. PMID:35848020. olfactory bulb integrity in frontotemporal dementia and alzheimer's disease. 2022-07-18 2023-08-14 Not clear
Zarui A Melikyan, María M Corrada, Anne-Marie Leiby, Seyed Ahmad Sajjadi, Syed Bukhari, Thomas J Montine, Claudia H Kawa. Cognitive resilience to three dementia-related neuropathologies in an oldest-old man: A case report from The 90+ Study. Neurobiology of aging. vol 116. 2022-05-08. PMID:35526514. neuropathological examination revealed intermediate level of alzheimer's disease neuropathologic change (thal phase 5, braak nft stage iv, cerad score 3), lewy bodies and neurites in the olfactory bulb, brainstem and limbic areas (braak pd stage 4), tdp-43 inclusions in the amygdala and hippocampus (late stage 2), and a microvascular lesion in putamen. 2022-05-08 2023-08-13 human
Helen C Murray, Kory Johnson, Andrea Sedlock, Blake Highet, Birger Victor Dieriks, Praju Vikas Anekal, Richard L M Faull, Maurice A Curtis, Alan Koretsky, Dragan Mari. Lamina-specific immunohistochemical signatures in the olfactory bulb of healthy, Alzheimer's and Parkinson's disease patients. Communications biology. vol 5. issue 1. 2022-01-25. PMID:35075270. lamina-specific immunohistochemical signatures in the olfactory bulb of healthy, alzheimer's and parkinson's disease patients. 2022-01-25 2023-08-13 human
Helen C Murray, Kory Johnson, Andrea Sedlock, Blake Highet, Birger Victor Dieriks, Praju Vikas Anekal, Richard L M Faull, Maurice A Curtis, Alan Koretsky, Dragan Mari. Lamina-specific immunohistochemical signatures in the olfactory bulb of healthy, Alzheimer's and Parkinson's disease patients. Communications biology. vol 5. issue 1. 2022-01-25. PMID:35075270. we demonstrate this approach by cumulatively screening up to 100 markers on formalin-fixed paraffin-embedded sections of human olfactory bulb sourced from neurologically normal (no significant pathology), alzheimer's (ad), and parkinson's disease (pd) patients. 2022-01-25 2023-08-13 human
Shaymaa Rezk, Samah Lashen, Mohamed El-Adl, Gehad E Elshopakey, Mona M Elghareeb, Basma M Hendam, Thomas Caceci, Carlo Cenciarelli, Hany E Mare. Effects of Rosemary Oil (Rosmarinus officinalis) supplementation on the fate of the transplanted human olfactory bulb neural stem cells against ibotenic acid-induced neurotoxicity (Alzheimer model) in rat. Metabolic brain disease. 2022-01-25. PMID:35075502. effects of rosemary oil (rosmarinus officinalis) supplementation on the fate of the transplanted human olfactory bulb neural stem cells against ibotenic acid-induced neurotoxicity (alzheimer model) in rat. 2022-01-25 2023-08-13 human
J Kendall Berry, Daniel Co. Increased oscillatory power in a computational model of the olfactory bulb due to synaptic degeneration. Physical review. E. vol 104. issue 2-1. 2021-09-16. PMID:34525666. we thus demonstrate one potential mechanism involved in the increased gamma oscillations seen in some animal models of alzheimer's disease, and we highlight the potential that pathological olfactory bulb behavior presents as an early biomarker of disease. 2021-09-16 2023-08-13 Not clear
Melania Gonzalez-Rodriguez, Veronica Astillero-Lopez, Patricia Villanueva-Anguita, M Eugenia Paya-Rodriguez, Alicia Flores-Cuadrado, Sandra Villar-Conde, Isabel Ubeda-Banon, Alino Martinez-Marcos, Daniel Saiz-Sanche. Somatostatin and Astroglial Involvement in the Human Limbic System in Alzheimer's Disease. International journal of molecular sciences. vol 22. issue 16. 2021-09-15. PMID:34445147. altogether, we can conclude that somatostatin expression is highly reduced in the human hippocampus, but not the olfactory bulb, and may play a role in alzheimer's disease pathogenesis. 2021-09-15 2023-08-13 human
Mercedes Lachén-Montes, Ignacio Íñigo-Marco, Paz Cartas-Cejudo, Joaquín Fernández-Irigoyen, Enrique Santamarí. Olfactory Bulb Proteomics Reveals Widespread Proteostatic Disturbances in Mixed Dementia and Guides for Potential Serum Biomarkers to Discriminate Alzheimer Disease and Mixed Dementia Phenotypes. Journal of personalized medicine. vol 11. issue 6. 2021-07-05. PMID:34204996. olfactory bulb proteomics reveals widespread proteostatic disturbances in mixed dementia and guides for potential serum biomarkers to discriminate alzheimer disease and mixed dementia phenotypes. 2021-07-05 2023-08-13 human
Helen C Murray, Birger Victor Dieriks, Molly E V Swanson, Praju Vikas Anekal, Clinton Turner, Richard L M Faull, Leonardo Belluscio, Alan Koretsky, Maurice A Curti. The unfolded protein response is activated in the olfactory system in Alzheimer's disease. Acta neuropathologica communications. vol 8. issue 1. 2021-05-31. PMID:32665027. olfactory dysfunction is an early and prevalent symptom of alzheimer's disease (ad) and the olfactory bulb is a nexus of beta-amyloid plaque and tau neurofibrillary tangle (nft) pathology during early ad progression. 2021-05-31 2023-08-13 Not clear
Mercedes Lachen-Montes, Andrea González-Morales, Maialen Palomino, Karina Ausin, Marta Gómez-Ochoa, María Victoria Zelaya, Isidro Ferrer, Alberto Pérez-Mediavilla, Joaquín Fernández-Irigoyen, Enrique Santamarí. Early-Onset Molecular Derangements in the Olfactory Bulb of Tg2576 Mice: Novel Insights Into the Stress-Responsive Olfactory Kinase Dynamics in Alzheimer's Disease. Frontiers in aging neuroscience. vol 11. 2020-10-01. PMID:31244650. early-onset molecular derangements in the olfactory bulb of tg2576 mice: novel insights into the stress-responsive olfactory kinase dynamics in alzheimer's disease. 2020-10-01 2023-08-13 mouse
Patrick Delafontaine-Martel, Joel Lefebvre, Pier-Luc Tardif, Bernard I Lévy, Philippe Pouliot, Frédéric Lesag. Whole brain vascular imaging in a mouse model of Alzheimer's disease with two-photon microscopy. Journal of biomedical optics. vol 23. issue 7. 2019-12-16. PMID:29998647. focusing on the medial prefrontal cortex, cerebral cortex, the olfactory bulb, and the hippocampal formation, we compared the vd of three age groups (2-, 4.5-, and 8-months-old), for both wild type mice and a transgenic model (app/ps1) with pathology resembling alzheimer's disease (ad). 2019-12-16 2023-08-13 mouse
Rui Zheng, Zhong-Hao Zhang, Yu-Xi Zhao, Chen Chen, Shi-Zheng Jia, Xian-Chun Cao, Li-Ming Shen, Jia-Zuan Ni, Guo-Li Son. Transcriptomic Insights into the Response of the Olfactory Bulb to Selenium Treatment in a Mouse Model of Alzheimer's Disease. International journal of molecular sciences. vol 20. issue 12. 2019-12-10. PMID:31248178. transcriptomic insights into the response of the olfactory bulb to selenium treatment in a mouse model of alzheimer's disease. 2019-12-10 2023-08-13 mouse
Zhong-Hao Zhang, Chen Chen, Qiu-Yan Wu, Rui Zheng, Yao Chen, Qiong Liu, Jia-Zuan Ni, Guo-Li Son. Selenomethionine Ameliorates Neuropathology in the Olfactory Bulb of a Triple Transgenic Mouse Model of Alzheimer's Disease. International journal of molecular sciences. vol 17. issue 10. 2019-11-20. PMID:27689994. selenomethionine ameliorates neuropathology in the olfactory bulb of a triple transgenic mouse model of alzheimer's disease. 2019-11-20 2023-08-13 mouse
Mercedes Lachén-Montes, Andrea González-Morales, María Victoria Zelaya, Estela Pérez-Valderrama, Karina Ausín, Isidro Ferrer, Joaquín Fernández-Irigoyen, Enrique Santamarí. Olfactory bulb neuroproteomics reveals a chronological perturbation of survival routes and a disruption of prohibitin complex during Alzheimer's disease progression. Scientific reports. vol 7. issue 1. 2019-04-03. PMID:28831118. olfactory bulb neuroproteomics reveals a chronological perturbation of survival routes and a disruption of prohibitin complex during alzheimer's disease progression. 2019-04-03 2023-08-13 human
K A Josephs, D W Dickso. TDP-43 in the olfactory bulb in Alzheimer's disease. Neuropathology and applied neurobiology. vol 42. issue 4. 2018-02-12. PMID:26810591. tdp-43 in the olfactory bulb in alzheimer's disease. 2018-02-12 2023-08-13 Not clear
Stefan J Kempf, Athanasios Metaxas, María Ibáñez-Vea, Sultan Darvesh, Bente Finsen, Martin R Larse. An integrated proteomics approach shows synaptic plasticity changes in an APP/PS1 Alzheimer's mouse model. Oncotarget. vol 7. issue 23. 2018-01-17. PMID:27144524. the aim of this study was to elucidate the molecular signature of alzheimer's disease-associated amyloid pathology.we used the double appswe/ps1Δe9 mouse, a widely used model of cerebral amyloidosis, to compare changes in proteome, including global phosphorylation and sialylated n-linked glycosylation patterns, pathway-focused transcriptome and neurological disease-associated mirnaome with age-matched controls in neocortex, hippocampus, olfactory bulb and brainstem. 2018-01-17 2023-08-13 mouse