| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I Kovacs, I Torok, J Zombori, P Kas. Cholinergic structures and neuropathologic alterations in the olfactory bulb of Alzheimer's disease brain samples. Brain research. vol 789. issue 1. 1998-07-27. PMID:9602111. |
this report describes the laminar distribution of acetylcholinesterase-positive structures and the neuropathologic alterations in the human olfactory bulb of control and alzheimer's disease brain samples. |
1998-07-27 |
2023-08-12 |
human |
| I Kovács, I Török, J Zombori, P Kás. Neuropathologic changes in the olfactory bulb in Alzheimer's disease. Neurobiology (Budapest, Hungary). vol 4. issue 1-2. 1997-04-22. PMID:9116690. |
neuropathologic changes in the olfactory bulb in alzheimer's disease. |
1997-04-22 |
2023-08-12 |
Not clear |
| D L Samudralwar, C C Diprete, B F Ni, W D Ehmann, W R Markesber. Elemental imbalances in the olfactory pathway in Alzheimer's disease. Journal of the neurological sciences. vol 130. issue 2. 1996-03-25. PMID:8586977. |
concentrations of 11 trace elements were determined in 56 control and 98 alzheimer's disease (ad) olfactory bulb, olfactory tract, olfactory trigone, piriform cortex and amygdala specimens by instrumental neutron activation analysis. |
1996-03-25 |
2023-08-12 |
human |
| D Jaarsma, L Veenma-van der Duin, J Kor. N-acetylaspartate and N-acetylaspartylglutamate levels in Alzheimer's disease post-mortem brain tissue. Journal of the neurological sciences. vol 127. issue 2. 1995-05-08. PMID:7707082. |
the tissue concentrations of two related amino acid derivatives, n-acetylaspartate (naa) and n-acetylaspartylglutamate (naag) were determined in autopsy hippocampus, amygdala, cerebellar cortex and olfactory bulb of alzheimer's disease patients and age-matched non-demented controls, using reverse-phase hplc and fluorescence detection after precolumn derivatisation with the fluorophore 2-aminoanthracene. |
1995-05-08 |
2023-08-12 |
Not clear |
| D Jaarsma, L Veenma-van der Duin, J Kor. N-acetylaspartate and N-acetylaspartylglutamate levels in Alzheimer's disease post-mortem brain tissue. Journal of the neurological sciences. vol 127. issue 2. 1995-05-08. PMID:7707082. |
in alzheimer's disease, naa and naag concentrations were significantly reduced in the hippocampus (by 38 and 24%) and the amygdala (by 28 and 22%), but not in the olfactory bulb and the cerebellar cortex. |
1995-05-08 |
2023-08-12 |
Not clear |
| H J ter Laak, K Renkawek, F P van Worku. The olfactory bulb in Alzheimer disease: a morphologic study of neuron loss, tangles, and senile plaques in relation to olfaction. Alzheimer disease and associated disorders. vol 8. issue 1. 1994-06-17. PMID:8185881. |
the olfactory bulb in alzheimer disease: a morphologic study of neuron loss, tangles, and senile plaques in relation to olfaction. |
1994-06-17 |
2023-08-12 |
Not clear |
| A G Paolini, J S McKenzi. Effects of lesions in the horizontal diagonal band nucleus on olfactory habituation in the rat. Neuroscience. vol 57. issue 3. 1994-03-17. PMID:8309533. |
the nucleus of the horizontal limb of the diagonal band, a component of the basal forebrain magnocellular complex affected in alzheimer type dementia, supplies centrifugal innervation to the olfactory bulb. |
1994-03-17 |
2023-08-12 |
rat |
| R G Struble, H B Clar. Olfactory bulb lesions in Alzheimer's disease. Neurobiology of aging. vol 13. issue 4. 1992-09-21. PMID:1508297. |
olfactory bulb lesions in alzheimer's disease. |
1992-09-21 |
2023-08-11 |
Not clear |
| J K Youn. Alzheimer's disease and metal-containing glia. Medical hypotheses. vol 38. issue 1. 1992-07-30. PMID:1614354. |
considerable evidence suggests that in alzheimer's disease, olfactory bulb damage may be a primary factor, causing degeneration and neurofibrillary tangles primarily in neurons connected with this brain area. |
1992-07-30 |
2023-08-11 |
Not clear |
| M I Fonseca, J S Aguilar, A F Skorupa, W L Klei. Cellular mapping of m2 muscarinic receptors in rat olfactory bulb using an antiserum raised against a cytoplasmic loop peptide. Brain research. vol 563. issue 1-2. 1992-03-23. PMID:1786528. |
the mapping of m2-positive cells in olfactory bulb may be of particular interest because loss of this subtype and degeneration of the olfactory system have been observed in alzheimer's disease. |
1992-03-23 |
2023-08-11 |
mouse |
| R Loy, D Heyer, M Clagett-Dame, P S DiStefan. Localization of NGF receptors in normal and Alzheimer's basal forebrain with monoclonal antibodies against the truncated form of the receptor. Journal of neuroscience research. vol 27. issue 4. 1991-04-26. PMID:1964180. |
since these neurons project to olfactory bulb and cortex in rodent and primate brains, their loss may also reflect damage to the olfactory system in alzheimer's disease. |
1991-04-26 |
2023-08-11 |
human |
| N Yoshimura, S Kubota, Y Fukushima, H Kudo, H Ishigaki, Y Yoshid. Down's syndrome in middle age. Topographical distribution and immunoreactivity of brain lesions in an autopsied patient. Acta pathologica japonica. vol 40. issue 10. 1991-04-04. PMID:1963256. |
this distribution pattern was not different qualitatively from that in alzheimer's disease, and such a similarity was especially evident in the olfactory bulb, where many tufted and mitral cells as well as anterior olfactory nucleus cells showed nfts. |
1991-04-04 |
2023-08-11 |
Not clear |
| L D Loopuijt, J B Seben. Loss of dopamine receptors in the olfactory bulb of patients with Alzheimer's disease. Brain research. vol 529. issue 1-2. 1991-03-19. PMID:1980844. |
loss of dopamine receptors in the olfactory bulb of patients with alzheimer's disease. |
1991-03-19 |
2023-08-11 |
Not clear |
| N Yoshimur. Alzheimer's neurofibrillary changes in the olfactory bulb in myotonic dystrophy. Clinical neuropathology. vol 9. issue 5. 1991-02-28. PMID:2272144. |
alzheimer's neurofibrillary changes in the olfactory bulb in myotonic dystrophy. |
1991-02-28 |
2023-08-11 |
Not clear |
| T G Ohm, H Braa. Olfactory bulb changes in Alzheimer's disease. Acta neuropathologica. vol 73. issue 4. 1987-09-17. PMID:3618129. |
olfactory bulb changes in alzheimer's disease. |
1987-09-17 |
2023-08-11 |
Not clear |
| J Kahn, B H Anderton, C C Miller, J N Wood, M M Esir. Staining with monoclonal antibodies to neurofilaments distinguishes between subpopulations of neurofibrillary tangles, between groups of axons and between groups of dendrites. Journal of neurology. vol 234. issue 4. 1987-08-28. PMID:3112314. |
in alzheimer's disease, mab 1215 recognizes only a subpopulation of neurofibrillary tangles and stains a proportion of tangles in the hippocampus but none of those in the olfactory bulb. |
1987-08-28 |
2023-08-11 |
Not clear |
| R L Doty, P F Reyes, T Grego. Presence of both odor identification and detection deficits in Alzheimer's disease. Brain research bulletin. vol 18. issue 5. 1987-08-28. PMID:3607528. |
recent studies of alzheimer's disease patients have demonstrated (a) marked structural and biochemical alterations in brain regions associated with olfactory function (including the olfactory bulb and entorhinal cortex) and (b) decrements in the ability to identify odorants. |
1987-08-28 |
2023-08-11 |
Not clear |
| M M Esiri, G K Wilcoc. The olfactory bulbs in Alzheimer's disease. Journal of neurology, neurosurgery, and psychiatry. vol 47. issue 1. 1984-03-19. PMID:6693914. |
in alzheimer's disease neurofibrillary tangles were found in the anterior olfactory nucleus but not elsewhere in the olfactory bulb. |
1984-03-19 |
2023-08-12 |
Not clear |