| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mercedes Lachén-Montes, Andrea González-Morales, Xabier Martínez de Morentin, Estela Pérez-Valderrama, Karina Ausín, María Victoria Zelaya, Antonio Serna, Ester Aso, Isidro Ferrer, Joaquín Fernández-Irigoyen, Enrique Santamarí. An early dysregulation of FAK and MEK/ERK signaling pathways precedes the β-amyloid deposition in the olfactory bulb of APP/PS1 mouse model of Alzheimer's disease. Journal of proteomics. vol 148. 2017-11-27. PMID:27498392. |
an early dysregulation of fak and mek/erk signaling pathways precedes the β-amyloid deposition in the olfactory bulb of app/ps1 mouse model of alzheimer's disease. |
2017-11-27 |
2023-08-13 |
mouse |
| Emrin Horgusluoglu, Kelly Nudelman, Kwangsik Nho, Andrew J Sayki. Adult neurogenesis and neurodegenerative diseases: A systems biology perspective. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 174. issue 1. 2017-08-21. PMID:26879907. |
new neurons are generated throughout adulthood in two regions of the brain, the olfactory bulb and dentate gyrus of the hippocampus, and are incorporated into the hippocampal network circuitry; disruption of this process has been postulated to contribute to neurodegenerative diseases including alzheimer's disease and parkinson's disease. |
2017-08-21 |
2023-08-13 |
Not clear |
| Gabrielle F Ruggiero, Jeannette Y Wic. Olfaction: New Understandings, Diagnostic Applications. The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists. vol 31. issue 11. 2017-06-06. PMID:28107119. |
it's also an initial symptom of alzheimer's dementia (ad); the amyloid plaques and tangles characterizing ad invade the olfactory bulb and hippocampus early in its course, hampering odor identification. |
2017-06-06 |
2023-08-13 |
Not clear |
| Magdalena Misiak, Rebeca Vergara Greeno, Beverly A Baptiste, Peter Sykora, Dong Liu, Stephanie Cordonnier, Evandro F Fang, Deborah L Croteau, Mark P Mattson, Vilhelm A Boh. DNA polymerase β decrement triggers death of olfactory bulb cells and impairs olfaction in a mouse model of Alzheimer's disease. Aging cell. vol 16. issue 1. 2017-06-05. PMID:27686631. |
dna polymerase β decrement triggers death of olfactory bulb cells and impairs olfaction in a mouse model of alzheimer's disease. |
2017-06-05 |
2023-08-13 |
mouse |
| Ö Yaldizli, I-K Penner, T Yonekawa, Y Naegelin, J Kuhle, M Pardini, D T Chard, C Stippich, J-I Kira, K Bendfeldt, M Amann, E-W Radue, L Kappos, T Sprenge. The association between olfactory bulb volume, cognitive dysfunction, physical disability and depression in multiple sclerosis. European journal of neurology. vol 23. issue 3. 2016-12-13. PMID:26699999. |
olfactory bulb atrophy is associated with cognitive dysfunction in parkinson's and alzheimer's disease, and with major depression. |
2016-12-13 |
2023-08-13 |
Not clear |
| Zhi-Gang Yao, Hai-Yan Jing, Dong-Mei Wang, Bei-Bei Lv, Jia-Mei Li, Feng-Feng Liu, Hui Fan, Xi-Chao Sun, Ye-Jun Qin, Miao-Qing Zha. Valproic acid ameliorates olfactory dysfunction in APP/PS1 transgenic mice of Alzheimer's disease: Ameliorations from the olfactory epithelium to the olfactory bulb. Pharmacology, biochemistry, and behavior. vol 144. 2016-12-13. PMID:26948859. |
valproic acid ameliorates olfactory dysfunction in app/ps1 transgenic mice of alzheimer's disease: ameliorations from the olfactory epithelium to the olfactory bulb. |
2016-12-13 |
2023-08-13 |
mouse |
| María Victoria Zelaya, Estela Pérez-Valderrama, Xabier Martínez de Morentin, Teresa Tuñon, Isidro Ferrer, María Rosario Luquin, Joaquín Fernandez-Irigoyen, Enrique Santamarí. Olfactory bulb proteome dynamics during the progression of sporadic Alzheimer's disease: identification of common and distinct olfactory targets across Alzheimer-related co-pathologies. Oncotarget. vol 6. issue 37. 2016-09-20. PMID:26517091. |
olfactory bulb proteome dynamics during the progression of sporadic alzheimer's disease: identification of common and distinct olfactory targets across alzheimer-related co-pathologies. |
2016-09-20 |
2023-08-13 |
human |
| Adriana Servello, Alessandra Fioretti, Gianfranco Gualdi, Claudio Di Biasi, Angelo Pittalis, Saadi Sollaku, Silva Pavaci, Federica Tortorella, Marco Fusetti, Marco Valenti, Francesco Masedu, Mauro Cacciafesta, Vincenzo Marigliano, Evaristo Ettorre, Martina Pagliarell. Olfactory Dysfunction, Olfactory Bulb Volume and Alzheimer's Disease: Is There a Correlation? A Pilot Study1. Journal of Alzheimer's disease : JAD. vol 48. issue 2. 2016-06-28. PMID:26402003. |
olfactory dysfunction, olfactory bulb volume and alzheimer's disease: is there a correlation? |
2016-06-28 |
2023-08-13 |
Not clear |
| Carlos De la Rosa-Prieto, Daniel Saiz-Sanchez, Isabel Ubeda-Banon, Alicia Flores-Cuadrado, Alino Martinez-Marco. Neurogenesis, Neurodegeneration, Interneuron Vulnerability, and Amyloid-β in the Olfactory Bulb of APP/PS1 Mouse Model of Alzheimer's Disease. Frontiers in neuroscience. vol 10. 2016-06-15. PMID:27303258. |
neurogenesis, neurodegeneration, interneuron vulnerability, and amyloid-β in the olfactory bulb of app/ps1 mouse model of alzheimer's disease. |
2016-06-15 |
2023-08-13 |
mouse |
| Nai-An Xiao, Jing Zhang, Meng Zhou, Zhen Wei, Xi-Lin Wu, Xiao-Man Dai, Yuan-Gui Zhu, Xiao-Chun Che. Reduction of Glucose Metabolism in Olfactory Bulb is an Earlier Alzheimer's Disease-related Biomarker in 5XFAD Mice. Chinese medical journal. vol 128. issue 16. 2016-02-25. PMID:26265617. |
reduction of glucose metabolism in olfactory bulb is an earlier alzheimer's disease-related biomarker in 5xfad mice. |
2016-02-25 |
2023-08-13 |
mouse |
| Karlijn J Doorn, Andrea Goudriaan, Carla Blits-Huizinga, John G J M Bol, Annemieke J Rozemuller, Piet V J M Hoogland, Paul J Lucassen, Benjamin Drukarch, Wilma D J van de Berg, Anne-Marie van Da. Increased amoeboid microglial density in the olfactory bulb of Parkinson's and Alzheimer's patients. Brain pathology (Zurich, Switzerland). vol 24. issue 2. 2015-02-21. PMID:24033473. |
increased amoeboid microglial density in the olfactory bulb of parkinson's and alzheimer's patients. |
2015-02-21 |
2023-08-12 |
Not clear |
| Hany E S Marei, Amany Farag, Asma Althani, Nahla Afifi, Ahmed Abd-Elmaksoud, Samah Lashen, Shaymaa Rezk, Roberto Pallini, Patrizia Casalbore, Carlo Cenciarell. Human olfactory bulb neural stem cells expressing hNGF restore cognitive deficit in Alzheimer's disease rat model. Journal of cellular physiology. vol 230. issue 1. 2015-01-09. PMID:24911171. |
human olfactory bulb neural stem cells expressing hngf restore cognitive deficit in alzheimer's disease rat model. |
2015-01-09 |
2023-08-13 |
human |
| Hany E S Marei, Amany Farag, Asma Althani, Nahla Afifi, Ahmed Abd-Elmaksoud, Samah Lashen, Shaymaa Rezk, Roberto Pallini, Patrizia Casalbore, Carlo Cenciarell. Human olfactory bulb neural stem cells expressing hNGF restore cognitive deficit in Alzheimer's disease rat model. Journal of cellular physiology. vol 230. issue 1. 2015-01-09. PMID:24911171. |
in this study, we aim to demonstrate the fate of allogenic adult human olfactory bulb neural stem/progenitor cells (obnsc/npcs) transplanted into the rat hippocampus treated with ibotenic acid (ibo), a neurotoxicant specific to hippocampal cholinergic neurons that are lost in alzheimer's disease. |
2015-01-09 |
2023-08-13 |
human |
| Oiivier Bibari, Siak Lee, Tracey C Dickson, Stan Mitew, James C Vickers, Meng I Chua. Denervation of the olfactory bulb leads to decreased Aβ plaque load in a transgenic mouse model of Alzheimer' s disease. Current Alzheimer research. vol 10. issue 7. 2014-04-08. PMID:23905998. |
denervation of the olfactory bulb leads to decreased aβ plaque load in a transgenic mouse model of alzheimer' s disease. |
2014-04-08 |
2023-08-12 |
mouse |
| Daniel Saiz-Sanchez, Carlos De La Rosa-Prieto, Isabel Ubeda-Bañon, Alino Martinez-Marco. Interneurons and beta-amyloid in the olfactory bulb, anterior olfactory nucleus and olfactory tubercle in APPxPS1 transgenic mice model of Alzheimer's disease. Anatomical record (Hoboken, N.J. : 2007). vol 296. issue 9. 2014-03-27. PMID:23904197. |
interneurons and beta-amyloid in the olfactory bulb, anterior olfactory nucleus and olfactory tubercle in appxps1 transgenic mice model of alzheimer's disease. |
2014-03-27 |
2023-08-12 |
mouse |
| Hartmut P Burmeister, Thomas Bitter, Patrick M Heiler, Andrey Irintchev, Rosemarie Fröber, Matthias Dietzel, Pascal A Baltzer, Lothar R Schad, Jürgen R Reichenbach, Hilmar Gudziol, Orlando Guntinas-Lichius, Werner A Kaise. Imaging of lamination patterns of the adult human olfactory bulb and tract: in vitro comparison of standard- and high-resolution 3T MRI, and MR microscopy at 9.4 T. NeuroImage. vol 60. issue 3. 2012-08-06. PMID:22306806. |
alzheimer's disease, sinonasal disease) negatively affect the microstructural integrity of the olfactory bulb's (ob) cortical layers. |
2012-08-06 |
2023-08-12 |
human |
| Tharinda W Rajapaksha, William A Eimer, Thomas C Bozza, Robert Vassa. The Alzheimer's β-secretase enzyme BACE1 is required for accurate axon guidance of olfactory sensory neurons and normal glomerulus formation in the olfactory bulb. Molecular neurodegeneration. vol 6. 2012-04-24. PMID:22204380. |
the alzheimer's β-secretase enzyme bace1 is required for accurate axon guidance of olfactory sensory neurons and normal glomerulus formation in the olfactory bulb. |
2012-04-24 |
2023-08-12 |
mouse |
| Juan Hu, Xiang Wang, Dan Liu, Qun Wang, Ling-Qiang Zh. Olfactory deficits induce neurofilament hyperphosphorylation. Neuroscience letters. vol 506. issue 2. 2012-04-19. PMID:22094386. |
olfactory dysfunction, including structural abnormalities of the olfactory epithelium, the olfactory bulb and the central olfactory cortices is recognized as an early feature of alzheimer disease (ad), the most prevalent neurodegenerative disease in aged population characterized by intracellular neurofibrillary tangles (nfts). |
2012-04-19 |
2023-08-12 |
mouse |
| Letten F Saugsta. Infantile autism: a chronic psychosis since infancy due to synaptic pruning of the supplementary motor area. Nutrition and health. vol 20. issue 3-4. 2011-12-20. PMID:22141191. |
olfactory bulb is first affected in the alzheimer's and parkinson's disease. |
2011-12-20 |
2023-08-12 |
Not clear |
| Ying-Ying Zhu, Dao-Feng Ni, Cai-Min X. Gene expression profiles in the olfactory bulb from a rat model of Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 18. issue 3. 2010-06-30. PMID:19749438. |
gene expression profiles in the olfactory bulb from a rat model of alzheimer's disease. |
2010-06-30 |
2023-08-12 |
rat |