| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dorina V Pinkhasova, Laura E Jameson, Kendra D Conrow, Michael P Simeone, Allan Peter Davis, Thomas C Wiegers, Carolyn J Mattingly, Maxwell C K Leun. Regulatory Status of Pesticide Residues in Cannabis: Implications to Medical Use in Neurological Diseases. Current research in toxicology. vol 2. 2021-07-27. PMID:34308371. |
cholinergic, dopaminergic, and retrograde endocannabinoid signaling pathways were linked to 10 genetic variants of epilepsy patients. |
2021-07-27 |
2023-08-13 |
human |
| Stephanie M DeGasperis, Richard Webster, Daniela Poh. Cannabis Treatment in Children with Epilepsy: Practices of Canadian Neurologists. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 47. issue 4. 2021-07-13. PMID:32127067. |
despite the fact that many pediatric epilepsy patients across canada are currently being treated with cannabis, little is known about the attitudes of neurologists toward cannabinoid treatment of children with epilepsy. |
2021-07-13 |
2023-08-13 |
Not clear |
| Jillian L Capodice, Steven A Kapla. The endocannabinoid system, cannabis, and cannabidiol: Implications in urology and men's health. Current urology. vol 15. issue 2. 2021-06-26. PMID:34168527. |
the endocannabinoid system is a neuromodulatory system responsible for partial regulation of cognitive and emotional processes in the human central nervous system such as behavior, mood disorders, and neurologic disorders such as epilepsy. |
2021-06-26 |
2023-08-13 |
human |
| Rosa Maria Vitale, Fabio Arturo Iannotti, Pietro Amode. The (Poly)Pharmacology of Cannabidiol in Neurological and Neuropsychiatric Disorders: Molecular Mechanisms and Targets. International journal of molecular sciences. vol 22. issue 9. 2021-06-17. PMID:34062987. |
cannabidiol (cbd), the major nonpsychoactive cannabis constituent, has been proposed for the treatment of a wide panel of neurological and neuropsychiatric disorders, including anxiety, schizophrenia, epilepsy and drug addiction due to the ability of its versatile scaffold to interact with diverse molecular targets that are not restricted to the endocannabinoid system. |
2021-06-17 |
2023-08-13 |
Not clear |
| Andrew J Roebuck, Quentin Greba, Anna-Maria Smolyakova, Mariam Alaverdashvili, Wendie N Marks, Sumanta Garai, Samantha L Baglot, Gavin Petrie, Stuart M Cain, Terrance P Snutch, Ganesh A Thakur, Matthew N Hill, John G Howland, Robert B Laprairi. Positive allosteric modulation of type 1 cannabinoid receptors reduces spike-and-wave discharges in Genetic Absence Epilepsy Rats from Strasbourg. Neuropharmacology. vol 190. 2021-06-09. PMID:33845076. |
certain cannabinoids, such as cannabidiol (cbd), have shown promise in the treatment of pediatric epilepsies. |
2021-06-09 |
2023-08-13 |
rat |
| Shah Khalid, Faisal A Almalki, Taibi Ben Hadda, Ammar Bader, Tareq Abu-Izneid, Malika Berredjem, Eman R Elsharkawy, Ali M Alqahtan. Medicinal Applications of Cannabinoids Extracted from Cannabis sativa (L.): A New Route in the Fight Against COVID-19? Current pharmaceutical design. vol 27. issue 13. 2021-06-04. PMID:33267756. |
however, the approval of some cannabinoids by the fda (along with other recognized national medical health systems) has opened the horizon for the use of these natural drugs in medicines such as epidiolex® (cannabidiol, used for the treatment of severe forms of epilepsy) and sativex®(Δ |
2021-06-04 |
2023-08-13 |
Not clear |
| J Helen Cross, Hannah Coc. A perspective on cannabinoids for treating epilepsy: Do they really change the landscape? Neuropharmacology. vol 170. 2021-06-03. PMID:31770546. |
a perspective on cannabinoids for treating epilepsy: do they really change the landscape? |
2021-06-03 |
2023-08-13 |
Not clear |
| Rhys Richard Mould, Stanley W Botchway, James R C Parkinson, Elizabeth Louise Thomas, Geoffrey W Guy, Jimmy D Bell, Alistair V W Nun. Cannabidiol Modulates Mitochondrial Redox and Dynamics in MCF7 Cancer Cells: A Study Using Fluorescence Lifetime Imaging Microscopy of NAD(P)H. Frontiers in molecular biosciences. vol 8. 2021-05-30. PMID:34046425. |
cannabidiol modulates mitochondrial redox and dynamics in mcf7 cancer cells: a study using fluorescence lifetime imaging microscopy of nad(p)h. the cannabinoid, cannabidiol (cbd), is part of the plant's natural defense system that when given to animals has many useful medicinal properties, including activity against cancer cells, modulation of the immune system, and efficacy in epilepsy. |
2021-05-30 |
2023-08-13 |
Not clear |
| C Espinosa-Jove. Cannabinoids in epilepsy: Clinical efficacy and pharmacological considerations. Neurologia (Barcelona, Spain). 2021-05-27. PMID:32317123. |
cannabinoids in epilepsy: clinical efficacy and pharmacological considerations. |
2021-05-27 |
2023-08-13 |
Not clear |
| Juliana Andrea Ponton, Kim Smyth, Elias Soumbasis, Sergio Andres Llanos, Mark Lewis, Wilhelm August Meerholz, Robert Lawrence Tangua. A pediatric patient with autism spectrum disorder and epilepsy using cannabinoid extracts as complementary therapy: a case report. Journal of medical case reports. vol 14. issue 1. 2021-05-14. PMID:32958062. |
a pediatric patient with autism spectrum disorder and epilepsy using cannabinoid extracts as complementary therapy: a case report. |
2021-05-14 |
2023-08-13 |
Not clear |
| Katherine S Ong, John B Carlin, Michael Fahey, Jeremy L Freeman, Ingrid E Scheffer, Lynn Gillam, Monique Anderson, Md Hamidul Huque, Donna Legge, Nicole Dirnbauer, Brian Lilley, Simon Slota-Kan, Noel Cranswic. Protocol for a single patient therapy plan: A randomised, double-blind, placebo-controlled N-of-1 trial to assess the efficacy of cannabidiol in patients with intractable epilepsy. Journal of paediatrics and child health. vol 56. issue 12. 2021-05-14. PMID:32965057. |
the sptp has been designed to assess the efficacy at an individual level of a commercially available cannabinoid product, cannabidiol, in reducing seizure frequency in paediatric patients with intractable epilepsy. |
2021-05-14 |
2023-08-13 |
Not clear |
| Fotini Georgiou, Panayiotis Maghsoudlou, Panagiotis Loukaidis, D Markoullaki, Christiana Giorgi, Ioanna Christodoulou, Chrystalla Matsentido. Successful treatment of cannabinoid administration against refractory epilepsy in Batten disease: a case report. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 42. issue 3. 2021-05-14. PMID:32995993. |
successful treatment of cannabinoid administration against refractory epilepsy in batten disease: a case report. |
2021-05-14 |
2023-08-13 |
Not clear |
| Aditya Krishnan, Juliana Chizo Agwu, Chetana Kallappa, Rajesh Pande. Development of central precocious puberty following cannabinoid use for paediatric epilepsy: causal or coincidence? BMJ case reports. vol 14. issue 4. 2021-05-14. PMID:33858879. |
development of central precocious puberty following cannabinoid use for paediatric epilepsy: causal or coincidence? |
2021-05-14 |
2023-08-13 |
monkey |
| Ewa Galaj, Guo-Hua Bi, Hong-Ju Yang, Zheng-Xiong X. Cannabidiol attenuates the rewarding effects of cocaine in rats by CB2, 5-HT Neuropharmacology. vol 167. 2021-04-23. PMID:31437433. |
cannabidiol (cbd) is a u.s. fda-approved cannabinoid for the treatment of epilepsy and recently was reported to have therapeutic potential for other disorders. |
2021-04-23 |
2023-08-13 |
rat |
| Osama Y Muthaffa. Treating epilepsy with options other than antiepileptic medications. Neurosciences (Riyadh, Saudi Arabia). vol 25. issue 4. 2021-04-16. PMID:33130805. |
recently, cannabinoids have been approved for epilepsy treatment. |
2021-04-16 |
2023-08-13 |
Not clear |
| Claudia Taborda Gómez, Fabiana Lairion, Marisa Repetto, Miren Ettcheto, Amalia Merelli, Alberto Lazarowski, Jerónimo Auzmend. Cannabidiol (CBD) Alters the Functionality of Neutrophils (PMN). Implications in the Refractory Epilepsy Treatment. Pharmaceuticals (Basel, Switzerland). vol 14. issue 3. 2021-04-13. PMID:33807975. |
cannabidiol (cbd), a lipophilic cannabinoid compound without psychoactive effects, has emerged as adjuvant of anti-epileptic drugs (aeds) in the treatment of refractory epilepsy (re), decreasing the severity and/or frequency of seizures. |
2021-04-13 |
2023-08-13 |
Not clear |
| Alejando Fuerte-Hortigón, Jaime Gonçalves, Laura Zeballos, Rubén Masa, Ricardo Gómez-Nieto, Dolores E Lópe. Distribution of the Cannabinoid Receptor Type 1 in the Brain of the Genetically Audiogenic Seizure-Prone Hamster GASH/Sal. Frontiers in behavioral neuroscience. vol 15. 2021-04-13. PMID:33841106. |
it has become clear that agonist activation of central type i cannabinoid receptors (cb1r) reduces epileptogenesis in pre-clinical animal models of epilepsy. |
2021-04-13 |
2023-08-13 |
Not clear |
| Willian Lazarini-Lopes, Raquel A Do Val-da Silva, Rui M P da Silva-Júnior, Alexandra O S Cunha, Norberto Garcia-Cairasc. Cannabinoids in Audiogenic Seizures: From Neuronal Networks to Future Perspectives for Epilepsy Treatment. Frontiers in behavioral neuroscience. vol 15. 2021-03-03. PMID:33643007. |
cannabinoids in audiogenic seizures: from neuronal networks to future perspectives for epilepsy treatment. |
2021-03-03 |
2023-08-13 |
Not clear |
| Diogo M Lourenço, Leonor Ribeiro-Rodrigues, Ana M Sebastião, Maria J Diógenes, Sara Xapell. Neural Stem Cells and Cannabinoids in the Spotlight as Potential Therapy for Epilepsy. International journal of molecular sciences. vol 21. issue 19. 2021-02-23. PMID:33022963. |
neural stem cells and cannabinoids in the spotlight as potential therapy for epilepsy. |
2021-02-23 |
2023-08-13 |
Not clear |
| Diogo M Lourenço, Leonor Ribeiro-Rodrigues, Ana M Sebastião, Maria J Diógenes, Sara Xapell. Neural Stem Cells and Cannabinoids in the Spotlight as Potential Therapy for Epilepsy. International journal of molecular sciences. vol 21. issue 19. 2021-02-23. PMID:33022963. |
however, further studies and clinical trials are required to investigate the putative mechanisms by which cannabinoids can be used to treat epilepsy. |
2021-02-23 |
2023-08-13 |
Not clear |