| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hariprasath Ragupathy, Manasvi Vukku, Sandeep Kumar Barodi. Cell-Type-Specific Mitochondrial Quality Control in the Brain: A Plausible Mechanism of Neurodegeneration. International journal of molecular sciences. vol 24. issue 19. 2023-10-14. PMID:37833867. |
several common mechanisms are shared by genetically or pathologically distinct neurodegenerative diseases, such as excitotoxicity, mitochondrial deficits and oxidative stress, protein misfolding and translational dysfunction, autophagy and microglia activation. |
2023-10-14 |
2023-10-15 |
Not clear |
| Deqiang Fu, Xingyue Liang, Yuxuan Jiang, Jieping Liu, Xiaosi Lin, Quan Yang, Xue Chen, Ping Huang, Wei Wang, Wenlin W. Iron blocks autophagic flux and induces autophagosomes accumulation in microglia. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023-09-30. PMID:37777083. |
meanwhile, abnormal autophagy in microglia is closely related to the occurrence of neurodegenerative diseases. |
2023-09-30 |
2023-10-07 |
Not clear |
| Alejandro Lillo, Joan Serrano-Marín, Jaume Lillo, Iu Raïch, Gemma Navarro, Rafael Franc. Differential Gene Expression in Activated Microglia Treated with Adenosine A Cells. vol 12. issue 18. 2023-09-28. PMID:37759436. |
differential gene expression in activated microglia treated with adenosine a microglial activation often accompanies the plastic changes occurring in the brain of patients with neurodegenerative diseases. |
2023-09-28 |
2023-10-07 |
Not clear |
| Daniele Lana, Giada Magni, Elisa Landucci, Gary L Wenk, Domenico Edoardo Pellegrini-Giampietro, Maria Grazia Giovannin. Phenomic Microglia Diversity as a Druggable Target in the Hippocampus in Neurodegenerative Diseases. International journal of molecular sciences. vol 24. issue 18. 2023-09-28. PMID:37761971. |
phenomic microglia diversity as a druggable target in the hippocampus in neurodegenerative diseases. |
2023-09-28 |
2023-10-07 |
rat |
| Qin Fan, Yue-Zhang Wu, Xiao-Xi Jia, Ruhan A, Chu-Mou Liu, Wei-Wei Zhang, Zhi-Yue Chao, Dong-Hua Zhou, Yuan Wang, Jia Chen, Kang Xiao, Cao Chen, Qi Shi, Xiao-Ping Don. Increased Gal-3 Mediates Microglia Activation and Neuroinflammation via the TREM2 Signaling Pathway in Prion Infection. ACS chemical neuroscience. 2023-09-28. PMID:37769016. |
galectin 3 (gal-3) is one of the major elements for activating microglia and mediating neuroinflammation in some types of neurodegenerative diseases. |
2023-09-28 |
2023-10-07 |
Not clear |
| Samar F Darwish, Abdullah M M Elbadry, Amir S Elbokhomy, Ghidaa A Salama, Rania M Salam. The dual face of microglia (M1/M2) as a potential target in the protective effect of nutraceuticals against neurodegenerative diseases. Frontiers in aging. vol 4. 2023-09-25. PMID:37744008. |
the dual face of microglia (m1/m2) as a potential target in the protective effect of nutraceuticals against neurodegenerative diseases. |
2023-09-25 |
2023-10-07 |
Not clear |
| Chao Gao, Jingwen Jiang, Yuyan Tan, Shengdi Che. Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets. Signal transduction and targeted therapy. vol 8. issue 1. 2023-09-22. PMID:37735487. |
microglia in neurodegenerative diseases: mechanism and potential therapeutic targets. |
2023-09-22 |
2023-10-07 |
Not clear |
| Chao Gao, Jingwen Jiang, Yuyan Tan, Shengdi Che. Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets. Signal transduction and targeted therapy. vol 8. issue 1. 2023-09-22. PMID:37735487. |
microglia activation is observed in various neurodegenerative diseases. |
2023-09-22 |
2023-10-07 |
Not clear |
| Chao Gao, Jingwen Jiang, Yuyan Tan, Shengdi Che. Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets. Signal transduction and targeted therapy. vol 8. issue 1. 2023-09-22. PMID:37735487. |
here we comprehensively review the biology of microglia and the roles of microglia in neurodegenerative diseases, including alzheimer's disease, parkinson's disease, multiple system atrophy, amyotrophic lateral sclerosis, frontotemporal dementia, progressive supranuclear palsy, corticobasal degeneration, dementia with lewy bodies and huntington's disease. |
2023-09-22 |
2023-10-07 |
Not clear |
| Björn F Vahsen, Sumedha Nalluru, Georgia R Morgan, Lucy Farrimond, Emily Carroll, Yinyan Xu, Kaitlyn M L Cramb, Benazir Amein, Jakub Scaber, Antigoni Katsikoudi, Ana Candalija, Mireia Carcolé, Ruxandra Dafinca, Adrian M Isaacs, Richard Wade-Martins, Elizabeth Gray, Martin R Turner, Sally A Cowley, Kevin Talbo. C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9. Nature communications. vol 14. issue 1. 2023-09-22. PMID:37736756. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by progressive motor neuron loss, with additional pathophysiological involvement of non-neuronal cells such as microglia. |
2023-09-22 |
2023-10-07 |
human |
| Katsura Takano-Kawabe, Kazuyuki Matoba, Yoichi Nakamura, Mitsuaki Moriyam. Low Density Lipoprotein Receptor-related Protein 2 Expression and Function in Cultured Astrocytes and Microglia. Neurochemical research. 2023-09-13. PMID:37702891. |
activation of glial cells, astrocytes and microglia, has been observed in neurodegenerative diseases including alzheimer's disease (ad). |
2023-09-13 |
2023-10-07 |
mouse |
| Kaushiki Biswa. Microglia mediated neuroinflammation in neurodegenerative diseases: A review on the cell signaling pathways involved in microglial activation. Journal of neuroimmunology. vol 383. 2023-09-06. PMID:37672840. |
microglia mediated neuroinflammation in neurodegenerative diseases: a review on the cell signaling pathways involved in microglial activation. |
2023-09-06 |
2023-10-07 |
Not clear |
| Kaushiki Biswa. Microglia mediated neuroinflammation in neurodegenerative diseases: A review on the cell signaling pathways involved in microglial activation. Journal of neuroimmunology. vol 383. 2023-09-06. PMID:37672840. |
microglia, the immune sentinels of the central nervous system (cns), have emerged to be the central players in many neurological and neurodegenerative diseases. |
2023-09-06 |
2023-10-07 |
Not clear |
| Erik Nutma, Nurun Fancy, Maria Weinert, Stergios Tsartsalis, Manuel C Marzin, Robert C J Muirhead, Irene Falk, Marjolein Breur, Joy de Bruin, David Hollaus, Robin Pieterman, Jasper Anink, David Story, Siddharthan Chandran, Jiabin Tang, Maria C Trolese, Takashi Saito, Takaomi C Saido, Katharine H Wiltshire, Paula Beltran-Lobo, Alexandra Phillips, Jack Antel, Luke Healy, Marie-France Dorion, Dylan A Galloway, Rochelle Y Benoit, Quentin Amossé, Kelly Ceyzériat, Aurélien M Badina, Enikö Kövari, Caterina Bendotti, Eleonora Aronica, Carola I Radulescu, Jia Hui Wong, Anna M Barron, Amy M Smith, Samuel J Barnes, David W Hampton, Paul van der Valk, Steven Jacobson, Owain W Howell, David Baker, Markus Kipp, Hannes Kaddatz, Benjamin B Tournier, Philippe Millet, Paul M Matthews, Craig S Moore, Sandra Amor, David R Owe. Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases. Nature communications. vol 14. issue 1. 2023-08-28. PMID:37640701. |
translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases. |
2023-08-28 |
2023-09-07 |
mouse |
| Qi Huang, Yanfu Wang, Shanshan Chen, Fengxia Lian. Glycometabolic Reprogramming of Microglia in Neurodegenerative Diseases: Insights from Neuroinflammation. Aging and disease. 2023-08-23. PMID:37611905. |
glycometabolic reprogramming of microglia in neurodegenerative diseases: insights from neuroinflammation. |
2023-08-23 |
2023-09-07 |
Not clear |
| Heike Mrowetz, Mohamed H Kotob, Jennifer Forster, Iren Aydin, Michael Stefan Unger, Jana Lubec, Ahmed M Hussein, Jovana Malikovic, Daniel Daba Feyissa, Volker Korz, Harald Höger, Gert Lubec, Ludwig Aigne. Leukotriene signaling as molecular correlate for cognitive heterogeneity in aging: an exploratory study. Frontiers in aging neuroscience. vol 15. 2023-08-21. PMID:37600518. |
one putative mechanism underlying cognitive heterogeneity might be neuroinflammation, exerted through microglia, the brain's innate immune cells, as neuroinflammation is central to brain aging and neurodegenerative diseases. |
2023-08-21 |
2023-09-07 |
Not clear |
| Pei Y Ng, Cheng Zhang, Hu Li, Darren J Bake. Senescent Microglia Represent a Subset of Disease-Associated Microglia in P301S Mice. Journal of Alzheimer's disease : JAD. 2023-08-07. PMID:37545233. |
the existence and contribution of microglia with senescent-like alterations in the pathogenesis of age-related neurodegenerative diseases like alzheimer's disease (ad) have been suggested in recent years. |
2023-08-07 |
2023-08-14 |
mouse |
| Wenze Deng, Pengcheng Yi, Yanhong Xiong, Jun Ying, Yue Lin, Yao Dong, Gen Wei, Xifeng Wang, Fuzhou Hu. Gut Metabolites Acting on the Gut-Brain Axis: Regulating the Functional State of Microglia. Aging and disease. 2023-08-07. PMID:37548933. |
at the same time, we highlight the roles of gut metabolites affecting microglia in the pathogenesis of neurodegenerative diseases and neurodevelopmental disorders. |
2023-08-07 |
2023-08-14 |
Not clear |
| Yu Chen, Junren Chen, Ziwei Xing, Cheng Peng, Dan L. Autophagy in Neuroinflammation: A Focus on Epigenetic Regulation. Aging and disease. 2023-08-07. PMID:37548945. |
neuroinflammation, characterized by the secretion of abundant inflammatory mediators, proinflammatory polarization of microglia, and the recruitment of infiltrating myeloid cells to foci of inflammation, drives or exacerbates the pathological processes of central nervous system disorders, especially in neurodegenerative diseases. |
2023-08-07 |
2023-08-14 |
Not clear |
| Miao Wei, Guowei Zhang, Zeyu Huang, Xuemeng Ding, Qing Sun, Yujian Zhang, Rongrong Zhu, Huaijin Guan, Min J. ATP-P2X Journal of neuroinflammation. vol 20. issue 1. 2023-07-31. PMID:37525172. |
atp-p2x dysfunction of microglia during aging affects normal neuronal function and results in the occurrence of neurodegenerative diseases. |
2023-07-31 |
2023-08-14 |
Not clear |