| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicholas A Ettinger, Danielle Guffey, Shaniqua J Anum, Titilope Fasipe, Julie Katkin, Saleh Bhar, Gladstone Airewele, Arun Saini, Venée N Tubma. Multi-center retrospective study of children with sickle cell disease admitted to pediatric intensive care units in the United States. Scientific reports. vol 13. issue 1. 2023-05-16. PMID:37185357. |
we provide the first comprehensive multi-center report on picu interventions associated with death, the need for invasive respiratory support or stroke among critically ill children with scd. |
2023-05-16 |
2023-08-14 |
Not clear |
| Jennifer Light, Maria Boucher, Jacquelyn Baskin-Miller, Mike Winstea. Managing the Cerebrovascular Complications of Sickle Cell Disease: Current Perspectives. Journal of blood medicine. vol 14. 2023-04-21. PMID:37082003. |
stroke screening in children with scd is well-established using transcranial doppler ultrasound (tcd). |
2023-04-21 |
2023-08-14 |
Not clear |
| Arvind P Subramaniam, Charity I Oyedeji, Jhana S Parikh, Jody A Feld, John J Strous. Cognitive-motor dual-task interference in adults with sickle cell disease. Gait & posture. vol 102. 2023-04-06. PMID:37023564. |
sickle cell disease (scd) is a genetic disorder that causes physical and cognitive impairment due to hemolysis, painful vaso-occlusion episodes, joint avascular necrosis, and strokes. |
2023-04-06 |
2023-08-14 |
Not clear |
| Akram M Asbeutah, Akmal M Zahra, Hanan Al-Abboh, Abdullah A AlMajran, Adekunle Adekil. Repeat transcranial Doppler ultrasound imaging in Kuwaiti children with sickle cell disease after a 10-year interval: A prospective, cohort study. Health science reports. vol 6. issue 3. 2023-03-30. PMID:36992713. |
transcranial doppler imaging (tcdi) of the cerebral arteries is the method of choice to predict patients with sickle cell disease (scd) at risk for stroke. |
2023-03-30 |
2023-08-14 |
Not clear |
| Rimi Hazra, Holland Hubert, Lynda Little-Ihrig, Samit Ghosh, Solomon Ofori-Acquah, Xiaoming Hu, Enrico M Novell. Insulin-like Growth Factor-1 Prevents Hypoxia/Reoxygenation-Induced White Matter Injury in Sickle Cell Mice. Biomedicines. vol 11. issue 3. 2023-03-29. PMID:36979670. |
occlusion of cerebral blood vessels causes acute cerebral hypoxia-an important trigger of ischemic white matter injury and stroke in sickle cell disease (scd). |
2023-03-29 |
2023-08-14 |
mouse |
| Kesava Mandalaneni, Priyanka Venkatapathappa, Sarah Koshy, Gabrielle Walcott-Bedeau, Vajinder Sing. Transcranial Doppler Ultrasonography-Related Research in the Caribbean Region. Cureus. vol 15. issue 2. 2023-03-23. PMID:36949970. |
tcd has been identified as a cost-effective tool for real-time monitoring of cerebral blood flow in many clinical settings, including stroke and scd, which are prevalent in the caribbean. |
2023-03-23 |
2023-08-14 |
Not clear |
| Suella Martino, Rym Chouk Turki, Fouzia Zouiti, Romain Fort, Sadaf Pakdaman, Stéphanie Forté, Dehbia Menouche, David Calvet, Thomas Rupp, France Pirenne, Pablo Bartolucc. Near-Infrared Spectroscopy Demonstrates the Benefit of Erythracytapheresis in Sickle Cell Disease Adult Patients with Cerebral Vasculopathy. Journal of clinical medicine. vol 12. issue 4. 2023-02-25. PMID:36835792. |
cerebral vasculopathy can induce chronic cerebral hypoperfusion leading to stroke in patients with sickle cell disease (scd) and is treated by blood exchange transfusion (bet). |
2023-02-25 |
2023-08-14 |
Not clear |
| Asmaa A Mahmoud, Sameh A Abd El Naby, Ahmed S Abdelgawad, Marwa Sabry Rizq, Nahla M S Abd El Had. Brain-derived neurotrophic factor and neuroimaging in pediatric patients with sickle cell disease. Pediatric research. 2023-02-11. PMID:36774398. |
the risk of neurological complications is increased in children with sickle cell disease (scd), such as silent cerebral infarction (sci) and stroke. |
2023-02-11 |
2023-08-14 |
Not clear |
| Asmaa A Mahmoud, Sameh A Abd El Naby, Ahmed S Abdelgawad, Marwa Sabry Rizq, Nahla M S Abd El Had. Brain-derived neurotrophic factor and neuroimaging in pediatric patients with sickle cell disease. Pediatric research. 2023-02-11. PMID:36774398. |
brain-derived neurotrophic factor (bdnf) is a nerve growth factor associated with elevated transcranial doppler (tcd) velocities and increased risk of stroke in scd patients. |
2023-02-11 |
2023-08-14 |
Not clear |
| Asmaa A Mahmoud, Sameh A Abd El Naby, Ahmed S Abdelgawad, Marwa Sabry Rizq, Nahla M S Abd El Had. Brain-derived neurotrophic factor and neuroimaging in pediatric patients with sickle cell disease. Pediatric research. 2023-02-11. PMID:36774398. |
so, we assessed the bdnf level in children with scd and its relation to neurological complication as silent stroke. |
2023-02-11 |
2023-08-14 |
Not clear |
| Erica M Sparkenbaugh, Michael W Henderson, Megan D Miller-Awe, Christina Abrams, Anton Ilich, Fatima Trebak, Nirupama Ramadas, Shantel A Vital, Dillon Bohinc, Kara Bane, Chunsheng Chen, Margi Patel, Michael Wallisch, Thomas Renné, Andras Gruber, Brian Cooley, David Gailani, Malgorzata Kasztan, Gregory M Vercellotti, John D Belcher, Felicity N E Gavins, Evi X Stavrou, Nigel S Key, Rafal Pawlinsk. Factor XII contributes to thrombotic complications and vaso-occlusion in sickle cell disease. Blood. 2023-01-27. PMID:36706361. |
a hypercoagulable state, chronic inflammation, and increased risk of venous thrombosis and stroke are prominent features in patients with sickle cell disease (scd). |
2023-01-27 |
2023-08-14 |
mouse |
| Eric Jay Earley, Shannon Kelly, Fang Fang, Cecília Salete Alencar, Daniela de Oliveira Werneck Rodrigues, Dahra Teles Soares Cruz, Jonathan M Flanagan, Russell E Ware, Xu Zhang, Victor Gordeuk, Mark Gladwin, Yingze Zhang, Mehdi Nouraie, Sergei Nekhai, Ester Sabino, Brian Custer, Carla Dinardo, Grier P Pag. Genome-wide association study of early ischaemic stroke risk in Brazilian individuals with sickle cell disease implicates ADAMTS2 and CDK18 and uncovers novel loci. British journal of haematology. 2023-01-05. PMID:36602125. |
ischaemic stroke is a common complication of sickle cell disease (scd) and without intervention can affect 11% of children with scd before the age of 20. |
2023-01-05 |
2023-08-14 |
Not clear |
| Eric Jay Earley, Shannon Kelly, Fang Fang, Cecília Salete Alencar, Daniela de Oliveira Werneck Rodrigues, Dahra Teles Soares Cruz, Jonathan M Flanagan, Russell E Ware, Xu Zhang, Victor Gordeuk, Mark Gladwin, Yingze Zhang, Mehdi Nouraie, Sergei Nekhai, Ester Sabino, Brian Custer, Carla Dinardo, Grier P Pag. Genome-wide association study of early ischaemic stroke risk in Brazilian individuals with sickle cell disease implicates ADAMTS2 and CDK18 and uncovers novel loci. British journal of haematology. 2023-01-05. PMID:36602125. |
within the trans-omics for precision medicine (topmed), a genome-wide association study (gwas) of ischaemic stroke was performed on 1333 individuals with scd from brazil (178 cases, 1155 controls). |
2023-01-05 |
2023-08-14 |
Not clear |
| Tamara A Hafiz, Sarah S Aldharman, Ruby N AlSubaie, Lena D Alzahrani, Ibrahim Ahmed J Albalawi, Yara A Alali, Maisaa M Yousuf, Hayat M Alharbi, Nawaf S Alamri, Syed F Jami. Blood Transfusion Vs. Hydroxyurea for Stroke Prevention in Children With Sickle Cell Anemia: A Systematic Review and Meta-Analysis. Cureus. vol 14. issue 11. 2022-12-26. PMID:36569706. |
blood transfusion and hydroxyurea (hu) therapy are used to prevent stroke in children with sickle cell disease (scd). |
2022-12-26 |
2023-08-14 |
human |
| Deepa Manwani, Arthur L Burnett, Jincy Paulose, Glorian P Yen, Tanya Burton, Amy Anderson, Sara Wang, Soyon Lee, Santosh L Sara. Treatment patterns and burden of complications associated with sickle cell disease: A US retrospective claims analysis. EJHaem. vol 3. issue 4. 2022-12-05. PMID:36467832. |
scd complications occurred frequently; in the overall population, the highest follow-up incidences per 1000 person-years were for acute kidney injury (53.1), chronic kidney disease (40.6), and stroke (39.0). |
2022-12-05 |
2023-08-14 |
Not clear |
| Tonner DeBeer, Lori C Jordan, Spencer Waddle, Chelsea Lee, Niral J Patel, Maria Garza, L Taylor Davis, Sumit Pruthi, Sky Jones, Manus J Donahu. Red cell exchange transfusions increase cerebral capillary transit times and may alter oxygen extraction in sickle cell disease. NMR in biomedicine. 2022-12-05. PMID:36468659. |
persons with sickle cell disease (scd) suffer from chronic hemolytic anemia, reduced blood oxygen content, and lifelong risk of silent and overt stroke. |
2022-12-05 |
2023-08-14 |
Not clear |
| Tonner DeBeer, Lori C Jordan, Spencer Waddle, Chelsea Lee, Niral J Patel, Maria Garza, L Taylor Davis, Sumit Pruthi, Sky Jones, Manus J Donahu. Red cell exchange transfusions increase cerebral capillary transit times and may alter oxygen extraction in sickle cell disease. NMR in biomedicine. 2022-12-05. PMID:36468659. |
major conventional stroke risk factors are absent in most individuals with scd, yet nearly 50% have evidence of brain infarcts by age 30 years, indicating alternative etiologies for ischemia. |
2022-12-05 |
2023-08-14 |
Not clear |
| Maria Aline Ferreira de Cerqueira, Luciana Maria Fortes Magalhães Castelo Branco Couto, Mírian Perpétua Palha Dias Parente, Juan Clinton Lleren. Sickle-Cell Disease and Stroke: Quality of Life of Patients in a Chronic Transfusion Regimen from the Caregivers' Perspective. Pediatric hematology and oncology. 2022-11-24. PMID:36420998. |
strokes affect up to 10% of children with sickle-cell disease (scd). |
2022-11-24 |
2023-08-14 |
Not clear |
| Maria Aline Ferreira de Cerqueira, Luciana Maria Fortes Magalhães Castelo Branco Couto, Mírian Perpétua Palha Dias Parente, Juan Clinton Lleren. Sickle-Cell Disease and Stroke: Quality of Life of Patients in a Chronic Transfusion Regimen from the Caregivers' Perspective. Pediatric hematology and oncology. 2022-11-24. PMID:36420998. |
this article aims to evaluate the quality of life (qol) of children and adolescents with scd undergoing a chronic transfusion regimen (ctr) for stroke prophylaxis, according to their caregivers' perception. |
2022-11-24 |
2023-08-14 |
Not clear |
| Maria Aline Ferreira de Cerqueira, Luciana Maria Fortes Magalhães Castelo Branco Couto, Mírian Perpétua Palha Dias Parente, Juan Clinton Lleren. Sickle-Cell Disease and Stroke: Quality of Life of Patients in a Chronic Transfusion Regimen from the Caregivers' Perspective. Pediatric hematology and oncology. 2022-11-24. PMID:36420998. |
it is possible that the occurrence of a stroke enhances the caregivers' negative perceptions about the qol of patients with scd. |
2022-11-24 |
2023-08-14 |
Not clear |