| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kristie Ramos, Kristin P Guilliams, Melanie E Field. The Development of Neuroimaging Biomarkers for Cognitive Decline in Sickle Cell Disease. Hematology/oncology clinics of North America. vol 36. issue 6. 2022-11-18. PMID:36400537. |
transcranial doppler ultrasound and structural brain mri are currently used for primary and secondary stroke prevention, but laboratory or imaging biomarkers do not currently exist that are specific to the risk of cognitive dysfunction in patients with scd. |
2022-11-18 |
2023-08-14 |
Not clear |
| Françoise Bernaudin, Cécile Arnaud, Annie Kamdem, Isabelle Hau, Fouad Madhi, Camille Jung, Ralph Epaud, Suzanne Verlha. Incidence, kinetics, and risk factors for intra- and extracranial cerebral arteriopathies in a newborn sickle cell disease cohort early assessed by transcranial and cervical color Doppler ultrasound. Frontiers in neurology. vol 13. 2022-10-03. PMID:36188389. |
the risk of stroke in children with sickle cell disease (scd) is detected by abnormal intracranial arterial time-averaged mean of maximum velocities (tamvs ≥200 cm/s). |
2022-10-03 |
2023-08-14 |
Not clear |
| Laura A Schieve, Gretchen M Simmons, Amanda B Payne, Karon Abe, Lewis L Hsu, Mary Hulihan, Shammara Pope, Sarah Rhie, Brandi Dupervil, W Craig Hoope. Vital Signs: Use of Recommended Health Care Measures to Prevent Selected Complications of Sickle Cell Anemia in Children and Adolescents - Selected U.S. States, 2019. MMWR. Morbidity and mortality weekly report. vol 71. issue 39. 2022-09-29. PMID:36173745. |
in 2014, an expert panel convened by the national heart, lung, and blood institute issued recommendations to prevent or reduce complications in children and adolescents with the most severe scd subtypes, known as sickle cell anemia (sca); recommendations included 1) annual screening of children and adolescents aged 2-16 years with transcranial doppler (tcd) ultrasound to identify those at risk for stroke and 2) offering hydroxyurea therapy to children and adolescents aged ≥9 months to reduce the risk for several life-threatening complications. |
2022-09-29 |
2023-08-14 |
Not clear |
| Ava Runge, Danielle Brazel, Zahra Pakba. Stroke in sickle cell disease and the promise of recent disease modifying agents. Journal of the neurological sciences. vol 442. 2022-09-23. PMID:36150233. |
this review highlights the burden of cerebrovascular disease in scd, including both stroke and silent cerebral infarct (sci). |
2022-09-23 |
2023-08-14 |
Not clear |
| Ava Runge, Danielle Brazel, Zahra Pakba. Stroke in sickle cell disease and the promise of recent disease modifying agents. Journal of the neurological sciences. vol 442. 2022-09-23. PMID:36150233. |
this review also reveals that options for primary and secondary stroke prevention in scd are still limited to hydroxyurea and blood transfusion, and that the role of aspirin and anticoagulation in scd stroke has not been adequately studied. |
2022-09-23 |
2023-08-14 |
Not clear |
| Ava Runge, Danielle Brazel, Zahra Pakba. Stroke in sickle cell disease and the promise of recent disease modifying agents. Journal of the neurological sciences. vol 442. 2022-09-23. PMID:36150233. |
further research is urgently needed to investigate their role in stroke prevention in scd, as these novel agents target the main stroke contributors in scd - hemolysis and vaso-occlusion. |
2022-09-23 |
2023-08-14 |
Not clear |
| Vafa Alakbarzade, Chinedu Maduakor, Usman Khan, Nader Khandanpour, Elizabeth Rhodes, Anthony C Pereir. Cerebrovascular disease in sickle cell disease. Practical neurology. 2022-09-19. PMID:36123118. |
current guidelines suggest that children and adults with scd who develop acute ischaemic stroke should be transfused without delay. |
2022-09-19 |
2023-08-14 |
Not clear |
| Emily A Kringle, Enrico M Novelli, Meryl A Butters, Elizabeth R Skidmor. Validation of the NIH Toolbox-Cognition Battery against legacy neurocognitive measures in adults with cognitive impairments: An exploratory analysis. Journal of the International Neuropsychological Society : JINS. 2022-09-05. PMID:36062530. |
the purpose of this exploratory study was to describe associations between nih toolbox-cognition battery subtests and legacy measures of neurocognitive function in two samples with neurological conditions (stroke and sickle cell disease (scd)). |
2022-09-05 |
2023-08-14 |
Not clear |
| Monica L Hulbert, Melanie E Fields, Kristin P Guilliams, Priyesha Bijlani, Shalini Shenoy, Slim Fellah, Alison S Towerman, Michael M Binkley, Robert C McKinstry, Joshua S Shimony, Yasheng Chen, Cihat Eldeniz, Dustin K Ragan, Katie D Vo, Hongyu An, Jin-Moo Lee, Andria L For. Normalization of cerebral hemodynamics following hematopoietic stem cell transplant in children with sickle cell disease. Blood. 2022-08-30. PMID:36040484. |
children with sickle cell disease (scd) demonstrate cerebral hemodynamic stress and are at high risk of strokes. |
2022-08-30 |
2023-08-14 |
human |
| Sara El Hoss, Wassim El Nemer, David C Ree. Precision Medicine and Sickle Cell Disease. HemaSphere. vol 6. issue 9. 2022-08-24. PMID:35999951. |
perhaps the best current example of precision medicine in scd is the selective use of blood transfusions as primary stroke prevention in children with evidence of cerebral vasculopathy. |
2022-08-24 |
2023-08-14 |
Not clear |
| Michael S Rallo, Omar Akel, Piyush Kalakoti, Hai Su. Characteristics and outcomes of stroke hospitalizations in patients with sickle cell disease and moyamoya syndrome. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. vol 31. issue 10. 2022-08-14. PMID:35964532. |
stroke is the leading cause of death in patients with sickle cell disease (scd). |
2022-08-14 |
2023-08-14 |
Not clear |
| Michael S Rallo, Omar Akel, Piyush Kalakoti, Hai Su. Characteristics and outcomes of stroke hospitalizations in patients with sickle cell disease and moyamoya syndrome. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. vol 31. issue 10. 2022-08-14. PMID:35964532. |
here, we detail the burden of moyamoya syndrome (mms) as a cause of stroke in patients with scd. |
2022-08-14 |
2023-08-14 |
Not clear |
| Arthemon Nguweneza, Valentina Josiane Ngo Bitoungui, Khuthala Mnika, Gaston Mazandu, Victoria Nembaware, Andre P Kengne, Ambroise Wonka. Clinical characteristics and risk factors of relative systemic hypertension and hypertension among sickle cell patients in Cameroon. Frontiers in medicine. vol 9. 2022-08-05. PMID:35928290. |
increased blood pressure (bp) has been associated with higher risk of stroke and mortality in sickle cell disease (scd). |
2022-08-05 |
2023-08-14 |
Not clear |
| Abdulaziz Mohammad Al-Sharydah, Hussain Khalid Al-Arfaj, Sari Saleh Al-Suhibani, Fahad Safran Al-Safran, Abdulrahman Hamad Al-Abdulwahhab, Saeed Ahmad Al-Jubran, Abdulhadi Ahmad AlSafla. Pediatric Stroke from Bench to Bedside: A Single-Center Experience in Saudi Arabia. Vascular health and risk management. vol 18. 2022-07-21. PMID:35860750. |
this study aimed to determine the genetic background, causative factors, and diagnostic and outcome measures of pediatric stroke in an area endemic to sickle cell disease (scd). |
2022-07-21 |
2023-08-14 |
Not clear |
| Lina Okar, Hadeel Ali Alzoubi, Safa Shukur Mahmud, Ahmed Elyas, Mohamed A Yassi. Dilemma in approach to stroke in sickle cell disease patient: A case report. Medicine. vol 101. issue 28. 2022-07-15. PMID:35839057. |
cerebrovascular accidents in sickle cell disease (scd) patients carry a high socioeconomic impact and represent the most important cause of morbidity, neurological deficits, and impaired quality of life in scd young population.patent foramen ovale (pfo) is prevalent in 25% of the general population and it is associated with ischemic stroke in the young population via paradoxical embolism, yet there are no specific guidelines to address how to manage scd patients with pfo who suffer a stroke. |
2022-07-15 |
2023-08-14 |
Not clear |
| Bhakti Gajjar, Sanjay Sharma, Erum Khan, Pranita Sharma, Pawan Jain, Vikas Goel, Arvind Neral, Jyotish Patel, Mamta Parmar, Kanika Sharma, Vijay K Sharma, Arvind K Sharm. Cerebral hemodynamics in children with sickle cell disease in India: An observational cohort study. Medicine. vol 101. issue 27. 2022-07-08. PMID:35801747. |
stroke and cerebral hemodynamic alterations are common among indian children with scd. |
2022-07-08 |
2023-08-14 |
Not clear |
| Brian R Peine, Michael U Callaghan, Joseph H Callaghan, Alexander K Glaro. Prophylactic Hydroxyurea Treatment Is Associated with Improved Cerebral Hemodynamics as a Surrogate Marker of Stroke Risk in Sickle Cell Disease: A Retrospective Comparative Analysis. Journal of clinical medicine. vol 11. issue 12. 2022-06-24. PMID:35743561. |
sickle cell disease (scd) increases the incidence of childhood stroke eighty-fold. |
2022-06-24 |
2023-08-14 |
Not clear |
| Brian R Peine, Michael U Callaghan, Joseph H Callaghan, Alexander K Glaro. Prophylactic Hydroxyurea Treatment Is Associated with Improved Cerebral Hemodynamics as a Surrogate Marker of Stroke Risk in Sickle Cell Disease: A Retrospective Comparative Analysis. Journal of clinical medicine. vol 11. issue 12. 2022-06-24. PMID:35743561. |
a high mca blood velocity indicates increased stroke risk due to cerebral vasculopathy, and first-line treatment to prevent primary or recurrent strokes in high-risk children with scd has classically been chronic blood transfusions. |
2022-06-24 |
2023-08-14 |
Not clear |
| Brian R Peine, Michael U Callaghan, Joseph H Callaghan, Alexander K Glaro. Prophylactic Hydroxyurea Treatment Is Associated with Improved Cerebral Hemodynamics as a Surrogate Marker of Stroke Risk in Sickle Cell Disease: A Retrospective Comparative Analysis. Journal of clinical medicine. vol 11. issue 12. 2022-06-24. PMID:35743561. |
our retrospective study aimed to document the long-term effects of hu treatment compared with no hu treatment in children with scd, using tcd measurements as our primary outcome and a surrogate marker of stroke risk. |
2022-06-24 |
2023-08-14 |
Not clear |
| Nicolas Girerd, John Cleland, Stefan D Anker, William Byra, Carolyn S P Lam, David Lapolice, Mandeep R Mehra, Dirk J van Veldhuisen, Emmanuel Bresso, Zohra Lamiral, Barry Greenberg, Faiez Zanna. Inflammation and remodeling pathways and risk of cardiovascular events in patients with ischemic heart failure and reduced ejection fraction. Scientific reports. vol 12. issue 1. 2022-05-20. PMID:35595781. |
patients with the following first clinical events: hf hospitalization, scd and the composite of mi or stroke were matched with corresponding controls for age, sex and study drug. |
2022-05-20 |
2023-08-13 |
Not clear |