| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A A Wal. Oestrogen receptor beta is involved in the actions of oestrogens in the brain for affective behaviour, but not trophic effects in peripheral tissues. Journal of neuroendocrinology. vol 22. issue 2. 2010-08-18. PMID:20025628. |
by using this approach, it has been possible to differentiate the enhancing effects of e(2) on behavioural processes mediated by the hippocampus, such as affective behaviour, and the trophic effects that increase tumourigenesis and uterine growth. |
2010-08-18 |
2023-08-12 |
mouse |
| Megan C Holmes, Roderick N Carter, June Noble, Shruti Chitnis, Amy Dutia, Janice M Paterson, John J Mullins, Jonathan R Seckl, Joyce L W Ya. 11beta-hydroxysteroid dehydrogenase type 1 expression is increased in the aged mouse hippocampus and parietal cortex and causes memory impairments. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 20. 2010-06-04. PMID:20484633. |
11beta-hsd1 elevation appears causal, since aging (18 months) male transgenic mice with forebrain-specific 11beta-hsd1 overexpression ( approximately 50% in hippocampus) exhibit premature age-associated cognitive decline in the absence of altered circulating glucocorticoid levels or other behavioral (affective) deficits. |
2010-06-04 |
2023-08-12 |
mouse |
| Ali Javadapour, Gin S Malhi, Belinda Ivanovski, Xiaohua Chen, Wei Wen, Perminder Sachde. Hippocampal volumes in adults with bipolar disorder. The Journal of neuropsychiatry and clinical neurosciences. vol 22. issue 1. 2010-05-20. PMID:20160210. |
patients reporting fewer affective episodes did however have significantly larger left hippocampus volumes than comparison subjects. |
2010-05-20 |
2023-08-12 |
human |
| R Canbeyl. Sensorimotor modulation of mood and depression: an integrative review. Behavioural brain research. vol 207. issue 2. 2010-04-13. PMID:19913058. |
several lines of research on mood disorders reveal that depression involves a dysfunction in an affective fronto-limbic circuitry that involves the prefrontal cortices, the cingulate cortex, several limbic structures including the amygdala and the hippocampus, lower brainstem structures and the basal ganglia. |
2010-04-13 |
2023-08-12 |
Not clear |
| Susan R Sesack, Anthony A Grac. Cortico-Basal Ganglia reward network: microcircuitry. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 1. 2010-02-24. PMID:19675534. |
the ventral subiculum of the hippocampus provides contextual and spatial information, the basolateral amygdala conveys affective influence, and the prefrontal cortex provides an integrative impact on goal-directed behavior. |
2010-02-24 |
2023-08-12 |
Not clear |
| D Litteljohn, E Mangano, N Shukla, S Hayle. Interferon-gamma deficiency modifies the motor and co-morbid behavioral pathology and neurochemical changes provoked by the pesticide paraquat. Neuroscience. vol 164. issue 4. 2010-02-19. PMID:19782123. |
correspondingly, paraquat promoted somewhat divergent variations in neurochemical activity among wild-type and ifn-gamma null mice at brain sites important for both motor (striatum) and co-morbid affective pathologies (dorsal hippocampus, medial prefrontal cortex, and locus coeruleus). |
2010-02-19 |
2023-08-12 |
mouse |
| Alexander Todorov, Ingrid R Olso. Robust learning of affective trait associations with faces when the hippocampus is damaged, but not when the amygdala and temporal pole are damaged. Social cognitive and affective neuroscience. vol 3. issue 3. 2009-04-02. PMID:19015111. |
robust learning of affective trait associations with faces when the hippocampus is damaged, but not when the amygdala and temporal pole are damaged. |
2009-04-02 |
2023-08-12 |
human |
| Alexander Todorov, Ingrid R Olso. Robust learning of affective trait associations with faces when the hippocampus is damaged, but not when the amygdala and temporal pole are damaged. Social cognitive and affective neuroscience. vol 3. issue 3. 2009-04-02. PMID:19015111. |
the findings suggest that the hippocampus is not critical for learning affective associations between traits and faces. |
2009-04-02 |
2023-08-12 |
human |
| Paolo Brambilla, John P Hatch, Jair C Soare. Limbic changes identified by imaging in bipolar patients. Current psychiatry reports. vol 10. issue 6. 2009-02-27. PMID:18980734. |
the hippocampus and amygdala are key limbic regions for memory formation and emotion modulation that are potentially involved in the cognitive and affective symptoms of bipolar disorder. |
2009-02-27 |
2023-08-12 |
Not clear |
| Françoise S Maheu, Luigi Mazzone, Deborah P Merke, Margaret F Keil, Constantine A Stratakis, Daniel S Pine, Monique Erns. Altered amygdala and hippocampus function in adolescents with hypercortisolemia: a functional magnetic resonance imaging study of Cushing syndrome. Development and psychopathology. vol 20. issue 4. 2009-02-13. PMID:18838037. |
this first study of cerebral function in adolescents with chronic endogenous hypercortisolemia due to cushing syndrome demonstrates the presence of functional alterations in amygdala and hippocampus, which are not associated with affective or memory impairments. |
2009-02-13 |
2023-08-12 |
human |
| Lys Angela Favaroni Mendes, Leda Menescal-de-Oliveir. Role of cholinergic, opioidergic and GABAergic neurotransmission of the dorsal hippocampus in the modulation of nociception in guinea pigs. Life sciences. vol 83. issue 19-20. 2009-01-22. PMID:18854195. |
the hippocampus is also believed to play an important role in the affective and motivational components of pain perception. |
2009-01-22 |
2023-08-12 |
Not clear |
| Emilie Bonnet, Katia Touyarot, Serge Alfos, Véronique Pallet, Paul Higueret, Djoher Nora Abrou. Retinoic acid restores adult hippocampal neurogenesis and reverses spatial memory deficit in vitamin A deprived rats. PloS one. vol 3. issue 10. 2009-01-13. PMID:18941534. |
a dysfunction of retinoid hippocampal signaling pathway has been involved in the appearance of affective and cognitive disorders. |
2009-01-13 |
2023-08-12 |
rat |
| Alicia A Walf, Cheryl A Fry. Rapid and estrogen receptor beta mediated actions in the hippocampus mediate some functional effects of estrogen. Steroids. vol 73. issue 9-10. 2008-09-03. PMID:18342348. |
the steroid hormone, estradiol (e(2)), has numerous targets in the central nervous system, including the hippocampus, which plays a key role in cognition and affective behavior. |
2008-09-03 |
2023-08-12 |
rat |
| Kwok-Keung Leung, Tatia M C Lee, Zhuangwei Xiao, Zhaoxin Wang, John X X Zhang, Paul S F Yip, Leonard S W L. Neural activities for negative priming with affective stimuli: an fMRI study. Neuroscience letters. vol 433. issue 3. 2008-06-30. PMID:18281155. |
such attenuation of negative priming by negative affective words was associated with increased activities in the ventrolateral and medial frontal regions, the hippocampus, and supplementary motor areas. |
2008-06-30 |
2023-08-12 |
human |
| Regina Hünnerkopf, Alexander Strobel, Lise Gutknecht, Burkhard Brocke, Klaus Peter Lesc. Interaction between BDNF Val66Met and dopamine transporter gene variation influences anxiety-related traits. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 12. 2008-02-14. PMID:17392738. |
the involvement in neural plasticity and the mediation of effects of repeated stress exposure and long-term antidepressant treatment on hippocampal neurogenesis supports a critical role of brain-derived neurotrophic factor (bdnf) in the pathophysiology of affective and other stress-related disorders. |
2008-02-14 |
2023-08-12 |
human |
| Byeong-Taek Lee, Seong Whi Cho, Hyung Soo Khang, Boung-Chul Lee, Ihn-Geun Choi, In Kyoon Lyoo, Byung-Joo Ha. The neural substrates of affective processing toward positive and negative affective pictures in patients with major depressive disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 7. 2007-12-06. PMID:17688985. |
depressed individuals demonstrated lower activity in the right hippocampus and the right insula to negative affective pictures, whereas they showed lower activity in the right anterior cingulate cortex and the left insula to positive pictures. |
2007-12-06 |
2023-08-12 |
Not clear |
| Raag D Airan, Leslie A Meltzer, Madhuri Roy, Yuqing Gong, Han Chen, Karl Deisserot. High-speed imaging reveals neurophysiological links to behavior in an animal model of depression. Science (New York, N.Y.). vol 317. issue 5839. 2007-08-27. PMID:17615305. |
the hippocampus is one of several brain areas thought to play a central role in affective behaviors, but the underlying local network dynamics are not understood. |
2007-08-27 |
2023-08-12 |
rat |
| Bradford W Fento. Limbic associated pelvic pain: a hypothesis to explain the diagnostic relationships and features of patients with chronic pelvic pain. Medical hypotheses. vol 69. issue 2. 2007-08-10. PMID:17292560. |
the hypothesis is based on recent improvements in the understanding of pain processing pathways in the central nervous system, and in particular the role of limbic structures, especially the anterior cingulate cortex, hippocampus and amygdala, in chronic and affective pain perception. |
2007-08-10 |
2023-08-12 |
Not clear |
| Lisa A Catapano, Husseini K Manj. G protein-coupled receptors in major psychiatric disorders. Biochimica et biophysica acta. vol 1768. issue 4. 2007-05-30. PMID:17078926. |
dysfunction of multiple neurotransmitter and neuropeptide gpcrs in frontal cortex and limbic-related regions, such as the hippocampus, hypothalamus and brainstem, likely underlies the complex clinical picture that includes cognitive, perceptual, affective and motoric symptoms. |
2007-05-30 |
2023-08-12 |
Not clear |
| Cheryl A Frye, Madeline E Rhode. Progestin concentrations are increased following paced mating in midbrain, hippocampus, diencephalon, and cortex of rats in behavioral estrus, but only in midbrain of diestrous rats. Neuroendocrinology. vol 83. issue 5-6. 2007-01-22. PMID:17028418. |
separate reports indicate that manipulating 3alpha,5alpha-thp levels in the vta or hippocampus respectively can influence lordosis and affective behavior. |
2007-01-22 |
2023-08-12 |
rat |