| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniel B McKim, Anzela Niraula, Andrew J Tarr, Eric S Wohleb, John F Sheridan, Jonathan P Godbou. Neuroinflammatory Dynamics Underlie Memory Impairments after Repeated Social Defeat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 9. 2016-08-16. PMID:26937001. |
because the hippocampus is a key area involved in neuroplasticity, behavior, and cognition, we hypothesize that stress-induced neuroinflammation impairs hippocampal neurogenesis and promotes cognitive and affective behavioral deficits. |
2016-08-16 |
2023-08-13 |
Not clear |
| Gianina Toller, Babu Adhimoolam, Katherine P Rankin, Hans-Jürgen Huppertz, Martin Kurthen, Hennric Jokei. Right fronto-limbic atrophy is associated with reduced empathy in refractory unilateral mesial temporal lobe epilepsy. Neuropsychologia. vol 78. 2016-08-04. PMID:26363299. |
consistent with the brain regions underlying social cognition, our results show that lower affective and cognitive empathy was associated with smaller volume in predominantly right fronto-limbic regions, including the right hippocampus, parahippocampal gyrus, thalamus, fusiform gyrus, inferior temporal gyrus, dorsomedial and dorsolateral prefrontal cortices, and in the bilateral midbrain. |
2016-08-04 |
2023-08-13 |
human |
| Gerd Kempermann, Hongjun Song, Fred H Gag. Neurogenesis in the Adult Hippocampus. Cold Spring Harbor perspectives in biology. vol 7. issue 9. 2016-06-09. PMID:26330519. |
of the neurogenic zones in the adult brain, adult hippocampal neurogenesis attracts the most attention, because it is involved in higher cognitive function, most notably memory processes, and certain affective behaviors. |
2016-06-09 |
2023-08-13 |
Not clear |
| Andrea S Link, Fang Zheng, Christian Alzheime. Activin Signaling in the Pathogenesis and Therapy of Neuropsychiatric Diseases. Frontiers in molecular neuroscience. vol 9. 2016-05-31. PMID:27242425. |
enhancement of this pathway tunes the performance of glutamatergic and gabaergic synapses in a fashion that impacts on cognitive functions and affective behavior, counteracts death-inducing signals through extrasynaptic nmda receptors (nmdars), and stimulates adult neurogenesis in the hippocampus. |
2016-05-31 |
2023-08-13 |
Not clear |
| Melissa Lamar, Leah H Rubin, Olusola Ajilore, Rebecca Charlton, Aifeng Zhang, Shaolin Yang, Jamie Cohen, Anand Kuma. What Metabolic Syndrome Contributes to Brain Outcomes in African American & Caucasian Cohorts. Current Alzheimer research. vol 12. issue 7. 2016-04-28. PMID:26239040. |
we hypothesized incremental mets risk would negatively contribute to cognition and relevant neuroanatomy, e.g., memory and hippocampal volumes, and that this risk extends to affective functioning. |
2016-04-28 |
2023-08-13 |
human |
| María Llorens-Martín, Alberto Rábano, Jesús Ávil. The Ever-Changing Morphology of Hippocampal Granule Neurons in Physiology and Pathology. Frontiers in neuroscience. vol 9. 2016-02-02. PMID:26834550. |
given the recently acquired relevance of the dendritic branch as a functional synaptic unit required for memory storage, a full understanding of the morphological alterations observed in newborn neurons may have important consequences for the prevention and treatment of the cognitive and affective alterations that evolve in conjunction with impaired adult hippocampal neurogenesis. |
2016-02-02 |
2023-08-13 |
Not clear |
| Paul H Soloff, Richard White, Amro Omari, Karthik Ramaseshan, Vaibhav A Diwadka. Affective context interferes with brain responses during cognitive processing in borderline personality disorder: fMRI evidence. Psychiatry research. vol 233. issue 1. 2016-01-06. PMID:25982488. |
a stimulus-driven episodic memory task, using images from the international affective pictures system, targeted the hippocampus (hip). |
2016-01-06 |
2023-08-13 |
human |
| Yann S Mineur, Emily B Einstein, Matthew P Bentham, Mattis B Wigestrand, Sam Blakeman, Sylvia A Newbold, Marina R Picciott. Expression of the 5-HT1A serotonin receptor in the hippocampus is required for social stress resilience and the antidepressant-like effects induced by the nicotinic partial agonist cytisine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 4. 2016-01-05. PMID:25288485. |
we therefore knocked down 5-ht1a receptors in either the dorsal raphe (presynaptic autoreceptors) or the hippocampus (a brain area with high expression of 5-ht1a heteroreceptors sensitive to cholinergic effects on affective behaviors). |
2016-01-05 |
2023-08-13 |
mouse |
| M H Galinato, L Orio, C D Mandya. Methamphetamine differentially affects BDNF and cell death factors in anatomically defined regions of the hippocampus. Neuroscience. vol 286. 2015-09-14. PMID:25463524. |
given that hippocampal function and neurogenesis vary in a subregion-specific fashion, where dorsal hippocampus regulates spatial processing and has higher levels of neurogenesis, whereas ventral hippocampus regulates anxiety-related behaviors, these data suggest that methamphetamine self-administration initiates distinct allostatic changes in hippocampal subregions that may contribute to the altered synaptic activity in the hippocampus, which may underlie enhanced negative affective symptoms and perpetuation of the addiction cycle. |
2015-09-14 |
2023-08-13 |
rat |
| Stavros Skouras, Marcus Gray, Hugo Critchley, Stefan Koelsc. Superficial amygdala and hippocampal activity during affective music listening observed at 3 T but not 1.5 T fMRI. NeuroImage. vol 101. 2015-05-27. PMID:25026154. |
superficial amygdala and hippocampal activity during affective music listening observed at 3 t but not 1.5 t fmri. |
2015-05-27 |
2023-08-13 |
human |
| Stavros Skouras, Marcus Gray, Hugo Critchley, Stefan Koelsc. Superficial amygdala and hippocampal activity during affective music listening observed at 3 T but not 1.5 T fMRI. NeuroImage. vol 101. 2015-05-27. PMID:25026154. |
the findings raise concern over false negatives in the superficial amygdala and hippocampus in affective studies conducted under 1.5 t and caution that imaging improvements due to increasing magnetic field strength can be influenced by region-specific characteristics. |
2015-05-27 |
2023-08-13 |
human |
| Wei Huang, Guo-Li Ming, Hongjun Son. Experience matters: enrichment remodels synaptic inputs to adult-born neurons. Neuron. vol 85. issue 4. 2015-04-14. PMID:25695264. |
new neurons are continuously integrated into adult hippocampal circuitry and play important roles in cognitive and affective functions. |
2015-04-14 |
2023-08-13 |
Not clear |
| Rebecca A Brachman, Michael L Lehmann, Dragan Maric, Miles Herkenha. Lymphocytes from chronically stressed mice confer antidepressant-like effects to naive mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 4. 2015-04-07. PMID:25632130. |
changes in affective behavior, hippocampal cell proliferation, microglial activation states, and blood cytokine levels were examined in reconstituted stress-naive mice. |
2015-04-07 |
2023-08-13 |
mouse |
| Rebecca A Brachman, Michael L Lehmann, Dragan Maric, Miles Herkenha. Lymphocytes from chronically stressed mice confer antidepressant-like effects to naive mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 4. 2015-04-07. PMID:25632130. |
improvement in affective behavior is potentially mediated by reduced peripheral pro-inflammatory cytokine load, protective microglial activity, and increased hippocampal cell proliferation. |
2015-04-07 |
2023-08-13 |
mouse |
| Wei Deng, Fred H Gag. The effect of immature adult-born dentate granule cells on hyponeophagial behavior is related to their roles in learning and memory. Frontiers in systems neuroscience. vol 9. 2015-03-23. PMID:25798094. |
the neurogenesis hypothesis of depression is based on the correlation between the rate of adult hippocampal neurogenesis and the affective status of rodents. |
2015-03-23 |
2023-08-13 |
Not clear |
| Nils Kohn, Irina Falkenberg, Thilo Kellermann, Simon B Eickhoff, Ruben C Gur, Ute Habe. Neural correlates of effective and ineffective mood induction. Social cognitive and affective neuroscience. vol 9. issue 6. 2015-01-16. PMID:23576810. |
an increase in positive affective ratings correlated with activity in the amygdala, hippocampus and the fusiform gyrus (ffg), whereas reduced positive affect correlated with activity of the subgenual anterior cingulate cortex. |
2015-01-16 |
2023-08-12 |
human |
| Stefan M Gold, Mary-Frances O'Connor, Raja Gill, Kyle C Kern, Yonggang Shi, Roland G Henry, Daniel Pelletier, David C Mohr, Nancy L Sicott. Detection of altered hippocampal morphology in multiple sclerosis-associated depression using automated surface mesh modeling. Human brain mapping. vol 35. issue 1. 2014-08-11. PMID:22847919. |
significant associations were found between right hippocampal shape and affective symptoms but not vegetative symptoms of depression. |
2014-08-11 |
2023-08-12 |
human |
| Ian Mahar, Francis Rodriguez Bambico, Naguib Mechawar, José N Nobreg. Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects. Neuroscience and biobehavioral reviews. vol 38. 2014-08-08. PMID:24300695. |
similarly, although hippocampal neurogenesis is known to be negatively regulated by stress and positively regulated by antidepressant treatment, the role of neurogenesis in mediating affective behaviour in the context of stress remains an active area of investigation. |
2014-08-08 |
2023-08-12 |
Not clear |
| Qianqian Zhu, Kewei Xiao, Ming Yu, Minglu Niu, Chengqian Li, Yanxia Gao, Guo-Dong Li, Yu Zho. Ghrelin but not nesfatin-1 affects certain forms of learning and memory in both rats and mice. Brain research. vol 1541. 2014-07-28. PMID:24148307. |
in this study, we micro-infused ghrelin or nesfatin-1 into the lateral amygdala (la) or area ca1 of the dorsal hippocampus (ca1) and investigated the immediate effects of those two peptide hormones on cognitive and affective behaviors. |
2014-07-28 |
2023-08-12 |
human |
| Haipeng Liu, Jian Zhou, Liang Fang, Zhao Liu, Songhua Fan, Peng Xi. Acute tryptophan depletion reduces nitric oxide synthase in the rat hippocampus. Neurochemical research. vol 38. issue 12. 2014-07-21. PMID:24170240. |
these findings demonstrate atd does not influence affective behavior and spatial memory despite a direct effect on hippocampal nos. |
2014-07-21 |
2023-08-12 |
rat |