| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Will Casey, Thiviya Kumaran, Steven E Massey, Bud Mishr. How Mitochondrial Signaling Games May Shape and Stabilize the Nuclear-Mitochondrial Symbiosis. Biology. vol 13. issue 3. 2024-03-27. PMID:38534456. |
using a previously devised biomolecular signaling games approach, we model a sender-receiver information asymmetric game, in which the informed mitochondrial sender signals and the uninformed nuclear receiver may take actions (involving for example apoptosis, senescence, regeneration and autophagy/mitophagy). |
2024-03-27 |
2024-03-29 |
Not clear |
| Maria Sperrhacke, Sinje Leitzke, Björn Ahrens, Karina Reis. Breakdown of Phospholipid Asymmetry Triggers ADAM17-Mediated Rescue Events in Cells Undergoing Apoptosis. Membranes. vol 13. issue 8. 2023-08-25. PMID:37623781. |
breakdown of phospholipid asymmetry triggers adam17-mediated rescue events in cells undergoing apoptosis. |
2023-08-25 |
2023-09-07 |
Not clear |
| Julia F Baum, Huriye D Uzun, Thomas Günther Pomorsk. Visualizing Loss of Plasma Membrane Lipid Asymmetry Using Annexin V Staining. Bio-protocol. vol 13. issue 14. 2023-07-27. PMID:37497452. |
loss of plasma membrane lipid asymmetry contributes to many cellular functions and responses, including apoptosis, blood coagulation, and cell fusion. |
2023-07-27 |
2023-08-14 |
Not clear |
| Fei Chen, Mingtong Sun, Fushuai Peng, Yudong Lai, Zhensong Jiang, Wen Zhang, Tao Li, Xingzhi Jin. Compressive stress induces spinal vertebral growth plate chondrocytes apoptosis via Piezo1. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2023-02-01. PMID:36722421. |
reducing the expression of piezo1 in the concave side of the vertebral growth plate and inhibiting the apoptosis of chondrocytes in the bilateral vertebral growth plate caused by asymmetric stress on both sides of the concave vertebral body may be a promising treatment strategy for ais. |
2023-02-01 |
2023-08-14 |
mouse |
| Richard Villagrana, Rosa Laura López-Marqué. Plant transbilayer lipid asymmetry and the role of lipid flippases. Emerging topics in life sciences. 2022-12-23. PMID:36562347. |
this asymmetry is essential for cell survival and its loss is related to apoptosis. |
2022-12-23 |
2023-08-14 |
Not clear |
| Yukiko K Kaneko, Ami Morioka, Misaki Sano, Maho Tashiro, Naoya Watanabe, Nahoko Kasahara, Masato Nojiri, Chihiro Ishiwatari, Kentaro Ichinose, Akira Minami, Takashi Suzuki, Momoka Yamaguchi, Toshihide Kimura, Tomohisa Ishikaw. Asymmetric dimethylarginine accumulation under hyperglycemia facilitates β-cell apoptosis via inhibiting nitric oxide production. Biochemical and biophysical research communications. vol 637. 2022-11-17. PMID:36395692. |
asymmetric dimethylarginine accumulation under hyperglycemia facilitates β-cell apoptosis via inhibiting nitric oxide production. |
2022-11-17 |
2023-08-14 |
mouse |
| Hiroyuki Nakao, Minoru Nakan. Flip-Flop Promotion Mechanisms by Model Transmembrane Peptides. Chemical & pharmaceutical bulletin. vol 70. issue 8. 2022-07-31. PMID:35908916. |
energy-independent flip-flop promotion by phospholipid scramblases disrupts the asymmetry in several physiological processes, such as apoptosis and blood coagulation. |
2022-07-31 |
2023-08-14 |
Not clear |
| Ernesto Pérez, Avinashnarayan Venkatanarayan, Martha J Lundel. Hunchback prevents notch-induced apoptosis in the serotonergic lineage of Drosophila Melanogaster. Developmental biology. 2022-04-05. PMID:35381219. |
the three ew neurons are protected from notch-induced apoptosis by asymmetric distribution of numb protein, an inhibitor of notch signaling. |
2022-04-05 |
2023-08-13 |
drosophila_melanogaster |
| Matías A Pibuel, Mariángeles Díaz, Yamila Molinari, Daniela Poodts, Lucas Silvestroff, Silvina L Lompardía, Paula Franco, Silvia E Hajo. 4-Methylumbelliferone as a potent and selective antitumor drug on a glioblastoma model. Glycobiology. vol 31. issue 1. 2021-09-21. PMID:32472122. |
the antitumor effect of 4mu alone or combined with tmz was evaluated on gl26 cells by assessing the metabolic activity through the xtt assay, cell proliferation by brdu incorporation assay, migration by the wound healing assay, cell death by fluorescein diacetate/propidium iodide (fda/pi) staining, apoptosis by membrane asymmetry and dna fragmentation and metalloproteinase activity by zymography. |
2021-09-21 |
2023-08-13 |
Not clear |
| Joseph A Lyons, Milena Timcenko, Thibaud Dieudonné, Guillaume Lenoir, Poul Nisse. P4-ATPases: how an old dog learnt new tricks - structure and mechanism of lipid flippases. Current opinion in structural biology. vol 63. 2021-07-21. PMID:32492637. |
the resulting lipid asymmetry potentiates the membrane and is essential for a wide range of cellular processes such as vesicle biogenesis and trafficking and membrane protein regulation, whereas dissipation of lipid asymmetry is required in blood coagulation and apoptosis. |
2021-07-21 |
2023-08-13 |
human |
| Kana Aoki, Shinsuke Satoi, Shota Harada, Seiichi Uchida, Yoh Iwasa, Junichi Ikenouch. Coordinated changes in cell membrane and cytoplasm during maturation of apoptotic bleb. Molecular biology of the cell. vol 31. issue 8. 2021-06-02. PMID:32049595. |
in the late phase of apoptosis, the loss of asymmetry in phospholipids distribution caused the enlargement of blebs, which enabled translocation of damage-associated molecular patterns to the bleb cytoplasm and maturation of functional apoptotic blebs. |
2021-06-02 |
2023-08-13 |
Not clear |
| Hong-Xu Chen, Fu-Chao Liang, Ping Gu, Bian-Ling Xu, Hong-Jun Xu, Wen-Ting Wang, Jia-Yang Hou, Dong-Xiao Xie, Xi-Qing Chai, Sheng-Jun A. Exosomes derived from mesenchymal stem cells repair a Parkinson's disease model by inducing autophagy. Cell death & disease. vol 11. issue 4. 2021-03-31. PMID:32341347. |
furthermore, exos reached the substantia nigra through the blood-brain barrier (bbb) in vivo, relieved apomorphine-induced asymmetric rotation, reduced substantia nigra dopaminergic neuron loss and apoptosis, and upregulated the level of dopamine in the striatum. |
2021-03-31 |
2023-08-13 |
human |
| Hiroyuki Nakao, Yusuke Kimura, Ami Sakai, Keisuke Ikeda, Minoru Nakan. Development of membrane-insertable lipid scrambling peptides: A time-resolved small-angle neutron scattering study. Structural dynamics (Melville, N.Y.). vol 8. issue 2. 2021-03-25. PMID:33758768. |
the promotion of flip-flop by phospholipid scramblases causes the loss of membrane lipid asymmetry, which is involved in apoptosis, blood coagulation, and viral infection. |
2021-03-25 |
2023-08-13 |
Not clear |
| Jee-Hae Kang, Hyun-Mi Ko, Geum-Dong Han, Su-Young Lee, Jung-Sun Moon, Min-Seok Kim, Jeong-Tae Koh, Sun-Hun Ki. Dual role of phosphatidylserine and its receptors in osteoclastogenesis. Cell death & disease. vol 11. issue 7. 2021-03-23. PMID:32612123. |
fusion and apoptosis share a breakdown of the membrane phospholipids asymmetry, modes of which are largely unknown in osteoclastogenesis. |
2021-03-23 |
2023-08-13 |
mouse |
| Haoyuan Jing, Yanbin Wang, Parth Rakesh Desai, Kumaran S Ramamurthi, Siddhartha Da. Lipid flip-flop and desorption from supported lipid bilayers is independent of curvature. PloS one. vol 15. issue 12. 2021-03-19. PMID:33378379. |
flip-flop of lipids of the lipid bilayer (lbl) constituting the plasma membrane (pm) plays a crucial role in a myriad of events ranging from cellular signaling and regulation of cell shapes to cell homeostasis, membrane asymmetry, phagocytosis, and cell apoptosis. |
2021-03-19 |
2023-08-13 |
Not clear |
| Farhan Chaudhry, Hideki Kawai, Kipp W Johnson, Navneet Narula, Aditya Shekhar, Fayzan Chaudhry, Takehiro Nakahara, Takashi Tanimoto, Dongbin Kim, Matthew K M Y Adapoe, Francis G Blankenberg, Jeffrey A Mattis, Koon Y Pak, Phillip D Levy, Yukio Ozaki, Eloisa Arbustini, H William Strauss, Artiom Petrov, Valentin Fuster, Jagat Narul. Molecular Imaging of Apoptosis in Atherosclerosis by Targeting Cell Membrane Phospholipid Asymmetry. Journal of the American College of Cardiology. vol 76. issue 16. 2021-02-09. PMID:33059832. |
molecular imaging of apoptosis in atherosclerosis by targeting cell membrane phospholipid asymmetry. |
2021-02-09 |
2023-08-13 |
Not clear |
| Anjali Gupta, Thomas Korte, Andreas Herrmann, Thorsten Wohlan. Plasma membrane asymmetry of lipid organization: fluorescence lifetime microscopy and correlation spectroscopy analysis. Journal of lipid research. vol 61. issue 2. 2021-02-08. PMID:31857388. |
a cell invests significant energy to maintain this asymmetry and uses it to regulate important biological processes, such as apoptosis and vesiculation. |
2021-02-08 |
2023-08-13 |
Not clear |
| Tomomi Suzuki, Tetsuo Mioka, Kazuma Tanaka, Akira Nagatan. An optogenetic system to control membrane phospholipid asymmetry through flippase activation in budding yeast. Scientific reports. vol 10. issue 1. 2020-12-10. PMID:32719316. |
lipid asymmetry in biological membranes is essential for various cell functions, such as cell polarity, cytokinesis, and apoptosis. |
2020-12-10 |
2023-08-13 |
Not clear |
| José Carlos Bozelli, Yu H Hou, Shirley Schreier, Richard M Epan. Lipid asymmetry of a model mitochondrial outer membrane affects Bax-dependent permeabilization. Biochimica et biophysica acta. Biomembranes. vol 1862. issue 8. 2020-10-22. PMID:32126227. |
in addition, by a direct comparison with its lipid symmetrical counterpart it is shown that asymmetric models were more resistant to tbid-promoted bax-permeabilization, suggesting a role played by mom lipid asymmetry on the mitochondria pathway of apoptosis. |
2020-10-22 |
2023-08-13 |
Not clear |
| Atsuko Uyeda, Takayoshi Watanabe, Takahiro Hohsaka, Tomoaki Matsuur. Different protein localizations on the inner and outer leaflet of cell-sized liposomes using cell-free protein synthesis. Synthetic biology (Oxford, England). vol 3. issue 1. 2020-10-02. PMID:32995515. |
the inner and outer leaflets of the membrane consist of different phospholipid compositions, which are known to affect the function of membrane proteins, and the loss of the asymmetry has been reported to lead to cell apoptosis. |
2020-10-02 |
2023-08-13 |
Not clear |