| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jason M Keil, Daniel Z Doyle, Adel Qalieh, Mandy M Lam, Owen H Funk, Yaman Qalieh, Lei Shi, Nitesh Mohan, Alice Sorel, Kenneth Y Kwa. Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80. Nature communications. vol 11. issue 1. 2020-09-09. PMID:32737294. |
unexpectedly, sensitivity to loss of ino80-mediated hr is dependent on npc division mode: ino80 deletion leads to unrepaired dna breaks and apoptosis in symmetric npc-npc divisions, but not in asymmetric neurogenic divisions. |
2020-09-09 |
2023-08-13 |
Not clear |
| Zhaokang Cui, Lingzhu Yu, Xiayan Shi Yang, Yu Zhang, Xiaoyan Shi, Yu Li, Qiuju Chen, Bo Xion. Brefeldin A impairs porcine oocyte meiotic maturation via interruption of organelle dynamics. Journal of cellular physiology. vol 234. issue 11. 2020-05-29. PMID:30950061. |
previous investigations have shown that bfa induces the apoptosis of cancer cells in mitosis and impairs asymmetric spindle positioning in meiosis. |
2020-05-29 |
2023-08-13 |
Not clear |
| Dan Ding, Jing Liang, Haibin Shi, Ryan T K Kwok, Meng Gao, Guangxue Feng, Youyong Yuan, Ben Zhong Tang, Bin Li. Light-up bioprobe with aggregation-induced emission characteristics for real-time apoptosis imaging in target cancer cells. Journal of materials chemistry. B. vol 2. issue 2. 2020-04-08. PMID:32261611. |
application of the asymmetric light-up probe for real-time targeted imaging of cancer cell apoptosis is successfully demonstrated using integrin α |
2020-04-08 |
2023-08-13 |
Not clear |
| Meng Wang, Xin Wang, Yuan Li, Qiang Xiao, Xiao-Hai Cui, Guo-Dong Xiao, Ji-Chang Wang, Chong-Wen Xu, Hong Ren, Dapeng Li. Nutlin-3-Induced Sensitization of Non-Small Cell Lung Cancer Stem Cells to Axitinib-Induced Apoptosis Through Repression of Akt1/Wnt Signaling. Oncology research. vol 27. issue 9. 2020-03-20. PMID:30832755. |
increased p53 expression stimulated the induction of apoptosis by axitinib and promoted asymmetric cell division (acd) of nsclc cscs. |
2020-03-20 |
2023-08-13 |
Not clear |
| Claire Levrier, Anja Rockstroh, Brian Gabrielli, Maria Kavallaris, Melanie Lehman, Rohan A Davis, Martin C Sadowski, Colleen C Nelso. Discovery of thalicthuberine as a novel antimitotic agent from nature that disrupts microtubule dynamics and induces apoptosis in prostate cancer cells. Cell cycle (Georgetown, Tex.). vol 17. issue 5. 2019-09-17. PMID:28749250. |
th induced a strong accumulation of lncap cells in mitosis, severe mitotic spindle defects, and asymmetric cell divisions, ultimately leading to mitotic catastrophe accompanied by cell death through apoptosis. |
2019-09-17 |
2023-08-13 |
Not clear |
| Janine Denise Brunner, Stephan Schenc. Preparation of Proteoliposomes with Purified TMEM16 Protein for Accurate Measures of Lipid Scramblase Activity. Methods in molecular biology (Clifton, N.J.). vol 1949. 2019-07-15. PMID:30790257. |
while flippases and floppases establish membrane asymmetry, scramblases randomize the lipid distribution and play pivotal roles during blood clotting, apoptosis, and in processes such as n-linked glycosylation of proteins. |
2019-07-15 |
2023-08-13 |
Not clear |
| Sarah-Lena Offenburger, Dalila Bensaddek, Alejandro Brenes Murillo, Angus I Lamond, Anton Gartne. Comparative genetic, proteomic and phosphoproteomic analysis of C. elegans embryos with a focus on ham-1/STOX and pig-1/MELK in dopaminergic neuron development. Scientific reports. vol 7. issue 1. 2019-01-08. PMID:28659600. |
proteins showing changes in either abundance, or phosphorylation levels, between wild-type and pig-1 mutant embryos are predominantly connected with processes including cell cycle, asymmetric cell division, apoptosis and actomyosin-regulation. |
2019-01-08 |
2023-08-13 |
caenorhabditis_elegans |
| Fernanda Gallinaro Pessoa, Charles Mady, Keila Cardoso Barbosa Fonseca, Adriana Morgan de Oliveira-Fonoff, Vera Maria Cury Salemi, Maurício Rodrigues Jordão, Fabio Fernandes, Felix José Alvarez Ramire. Erythropoietin reduces collagen deposition after myocardial infarction but does not improve cardiac function. Canadian journal of physiology and pharmacology. vol 96. issue 6. 2018-10-03. PMID:29120671. |
we quantified asymmetric dimethylarginine and glutathione by elisa, and used real-time pcr to assess apoptosis and inflammation. |
2018-10-03 |
2023-08-13 |
rat |
| Marie Markones, Carina Drechsler, Michael Kaiser, Louma Kalie, Heiko Heerklotz, Sebastian Fiedle. Engineering Asymmetric Lipid Vesicles: Accurate and Convenient Control of the Outer Leaflet Lipid Composition. Langmuir : the ACS journal of surfaces and colloids. vol 34. issue 5. 2018-09-17. PMID:29294294. |
the loss of this asymmetry, for example the exposure of negatively charged lipids on the extracellular membrane leaflet of mammalian cells, is involved in apoptosis and occurs in tumor cells. |
2018-09-17 |
2023-08-13 |
Not clear |
| Julia Waizenegger, Albert Braeuning, Markus Templin, Alfonso Lampen, Stefanie Hessel-Pra. Structure-dependent induction of apoptosis by hepatotoxic pyrrolizidine alkaloids in the human hepatoma cell line HepaRG: Single versus repeated exposure. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 114. 2018-09-05. PMID:29458164. |
after 24 h of exposure only retronecine-type pa were cytotoxic in heparg cells and induced apoptosis indicated by a loss of membrane asymmetry, disruption of the mitochondrial membrane potential, and increased pro-caspase and parp cleavage. |
2018-09-05 |
2023-08-13 |
human |
| Kyrylo A Pyrshev, Andrey S Klymchenko, Gábor Csúcs, Alexander P Demchenk. Apoptosis and eryptosis: Striking differences on biomembrane level. Biochimica et biophysica acta. Biomembranes. vol 1860. issue 6. 2018-08-14. PMID:29573990. |
the cell plasma membrane plays an essential role in programmed cell death of nucleated cells (apoptosis) and erythrocytes (eryptosis), and its changes due to loss of transmembrane asymmetry are quite similar. |
2018-08-14 |
2023-08-13 |
Not clear |
| Yasuhiro Saito, Ridhdhi R Desai, Senthil K Muthuswam. Reinterpreting polarity and cancer: The changing landscape from tumor suppression to tumor promotion. Biochimica et biophysica acta. Reviews on cancer. vol 1869. issue 2. 2018-07-30. PMID:29369778. |
in addition to the traditional form of cell polarity, which is involved establishment of maintenance of normal cell structure and asymmetry, we propose that some mammalian polarity proteins also regulate subcellular polarity (intracellular asymmetry), which can improve cellular fitness to carry out functions such as proliferation, apoptosis, stress adaptation, stemness and organelle biology. |
2018-07-30 |
2023-08-13 |
drosophila_melanogaster |
| Weikang Guo, Zongli Diao, Wenhu Li. Asymmetric dimethylarginine downregulates sarco/endoplasmic reticulum calcium‑ATPase 3 and induces endoplasmic reticulum stress in human umbilical vein endothelial cells. Molecular medicine reports. vol 16. issue 5. 2018-06-06. PMID:28944875. |
the present study investigated the potential mechanisms of asymmetric dimethylarginine (adma)‑induced apoptosis in human umbilical vein endothelial cells (huvecs). |
2018-06-06 |
2023-08-13 |
human |
| Fu-Qing Zhang, Wei Lu, Wen-Xiao Yuan, Xin L. Regulation of c-Jun N-Terminal Protein Kinase (JNK) Pathway in Apoptosis of Endothelial Outgrowth Cells Induced by Asymmetric Dimethylarginine. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2018-03-13. PMID:28546532. |
regulation of c-jun n-terminal protein kinase (jnk) pathway in apoptosis of endothelial outgrowth cells induced by asymmetric dimethylarginine. |
2018-03-13 |
2023-08-13 |
Not clear |
| Fu-Qing Zhang, Wei Lu, Wen-Xiao Yuan, Xin L. Regulation of c-Jun N-Terminal Protein Kinase (JNK) Pathway in Apoptosis of Endothelial Outgrowth Cells Induced by Asymmetric Dimethylarginine. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2018-03-13. PMID:28546532. |
our aim in the present study was to investigate the effect of regulation of asymmetric dimethylarginine (adma) on eocs apoptosis and to explore the underlining mechanisms of c-jun n-terminal protein kinase (jnk) pathway in the process. |
2018-03-13 |
2023-08-13 |
Not clear |
| Sheng Ye, Xi Zhou, Jiafeng Lin, Peng Che. Asymmetric Dimethylarginine Induced Apoptosis and Dysfunction of Endothelial Progenitor Cells: Role of Endoplasmic Reticulum Stress Pathway. BioMed research international. vol 2017. 2018-03-07. PMID:28589144. |
asymmetric dimethylarginine induced apoptosis and dysfunction of endothelial progenitor cells: role of endoplasmic reticulum stress pathway. |
2018-03-07 |
2023-08-13 |
cattle |
| Lisa C Crowley, Brooke J Marfell, Adrian P Scott, Nigel J Waterhous. Quantitation of Apoptosis and Necrosis by Annexin V Binding, Propidium Iodide Uptake, and Flow Cytometry. Cold Spring Harbor protocols. vol 2016. issue 11. 2017-09-26. PMID:27803250. |
however, during apoptosis lipid asymmetry is lost and ps becomes exposed on the outer leaflet of the plasma membrane. |
2017-09-26 |
2023-08-13 |
Not clear |
| Jerome Teuliere, Gian Garrig. Size Matters: How C. elegans Asymmetric Divisions Regulate Apoptosis. Results and problems in cell differentiation. vol 61. 2017-07-26. PMID:28409303. |
size matters: how c. elegans asymmetric divisions regulate apoptosis. |
2017-07-26 |
2023-08-13 |
caenorhabditis_elegans |
| Claire Levrier, Martin C Sadowski, Anja Rockstroh, Brian Gabrielli, Maria Kavallaris, Melanie Lehman, Rohan A Davis, Colleen C Nelso. 6α-Acetoxyanopterine: A Novel Structure Class of Mitotic Inhibitor Disrupting Microtubule Dynamics in Prostate Cancer Cells. Molecular cancer therapeutics. vol 16. issue 1. 2017-06-29. PMID:27760837. |
at low nanomolar doses, this potent cytotoxic alkaloid from the australian endemic tree anopterus macleayanus induced a strong accumulation of lncap and pc-3 (prostate cancer) cells as well as hela (cervical cancer) cells in mitosis, severe mitotic spindle defects, and asymmetric cell divisions, ultimately leading to mitotic catastrophe accompanied by cell death through apoptosis. |
2017-06-29 |
2023-08-13 |
Not clear |
| Min-Jung Park, Ki-Seok Oh, Jong-Hyun Nho, Gye-Yeop Kim, Dong-Il Ki. Asymmetric dimethylarginine (ADMA) treatment induces apoptosis in cultured rat mesangial cells via endoplasmic reticulum stress activation. Cell biology international. vol 40. issue 6. 2017-02-21. PMID:26992443. |
asymmetric dimethylarginine (adma) treatment induces apoptosis in cultured rat mesangial cells via endoplasmic reticulum stress activation. |
2017-02-21 |
2023-08-13 |
rat |