| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sonaa Elango, Usha Subbiah, Jeong Jai. Differential Behaviour of Selenium Analogs against Anticancer Drug Induced Apoptosis of Lymphocytes in Human Peripheral Blood. Asian Pacific journal of cancer prevention : APJCP. vol 17. issue 5. 2017-01-31. PMID:27268624. |
biochemical alterations occurring in many cells during apoptosis include loss of plasma membrane phospholipid asymmetry, dna fragmentation, and activation of caspase-3. |
2017-01-31 |
2023-08-13 |
human |
| Xiang Yang, Wenna Zhao, Xiufang Hu, Xianxiao Hao, Fang Hong, Jianlong Wang, Liping Xiang, Yunhui Zhu, Yaofeng Yuan, Rodney J Y Ho, Wenfeng Wang, Jingwei Sha. Synthesis, Characterization, and Anticancer Activity of Novel Lipophilic Emodin Cationic Derivatives. Chemical biology & drug design. vol 86. issue 6. 2016-11-03. PMID:26108260. |
in addition, the confocal study showed that emodin derivative 9a (containing asymmetric hydrocarbon tails) was mainly localized in mitochondria, demonstrating a key role of the mitochondria-mediated apoptosis pathway in cancer cells. |
2016-11-03 |
2023-08-13 |
Not clear |
| Jiwei Ma, Shupeng Zhao, Guojun Gao, Haigang Chang, Pengju Ma, Baozhe Ji. Probucol Protects Against Asymmetric Dimethylarginine-Induced Apoptosis in the Cultured Human Brain Microvascular Endothelial Cells. Journal of molecular neuroscience : MN. vol 57. issue 4. 2016-08-24. PMID:26254912. |
probucol protects against asymmetric dimethylarginine-induced apoptosis in the cultured human brain microvascular endothelial cells. |
2016-08-24 |
2023-08-13 |
human |
| Jens P Andersen, Anna L Vestergaard, Stine A Mikkelsen, Louise S Mogensen, Madhavan Chalat, Robert S Molda. P4-ATPases as Phospholipid Flippases-Structure, Function, and Enigmas. Frontiers in physiology. vol 7. 2016-07-26. PMID:27458383. |
this generates and maintains membrane lipid asymmetry, a property essential for a wide variety of cellular processes such as vesicle budding and trafficking, cell signaling, blood coagulation, apoptosis, bile and cholesterol homeostasis, and neuronal cell survival. |
2016-07-26 |
2023-08-13 |
human |
| Hai-Jun Leng, Fu Peng, Sarah Zingales, Wei Huang, Biao Wang, Qian Zhao, Rui Zhou, Gu He, Cheng Peng, Bo Ha. Core-Scaffold-Inspired Asymmetric Synthesis of Polysubstituted Chiral Hexahydropyridazines that Potently Inhibit Breast Cancer Cell Proliferation by Inducing Apoptosis. Chemistry (Weinheim an der Bergstrasse, Germany). vol 21. issue 50. 2016-06-10. PMID:26498568. |
core-scaffold-inspired asymmetric synthesis of polysubstituted chiral hexahydropyridazines that potently inhibit breast cancer cell proliferation by inducing apoptosis. |
2016-06-10 |
2023-08-13 |
Not clear |
| Alper Sonmez, Cem Haymana, Aydogan Aydogdu, Serkan Tapan, Yalcin Basaran, Coskun Meric, Kamil Baskoy, Mustafa Dinc, Mahmut Yazici, Abdullah Taslipinar, Cem Barcin, Mahmut Ilker Yilmaz, Erol Bolu, Omer Aza. Endothelial dysfunction, insulin resistance and inflammation in congenital hypogonadism, and the effect of testosterone replacement. Endocrine journal. vol 62. issue 7. 2016-05-24. PMID:25924666. |
the demographic parameters, asymmetric dimethylarginine (adma), tnf-like weak inducer of apoptosis (tweak), high sensitive c reactive protein (hs-crp) and homeostatic model assessment of insulin resistance (homa-ir) levels were measured before and after trt. |
2016-05-24 |
2023-08-13 |
human |
| Wai Keung Christopher Lai, Ming Yin Ka. Homocysteine-Induced Endothelial Dysfunction. Annals of nutrition & metabolism. vol 67. issue 1. 2016-05-04. PMID:26201664. |
the potential mechanisms by which elevated plasma homocysteine level leads to reduction in nitric oxide bioavailability include the disruptive uncoupling of nitric oxide synthase activity and quenching of nitric oxide by oxidative stress, the enzymatic inhibition by asymmetric dimethylarginine, endoplasmic reticulum stress with eventual endothelial cell apoptosis, and chronic inflammation/prothrombotic conditions. |
2016-05-04 |
2023-08-13 |
Not clear |
| Zhiyun Cao, Xuzheng Chen, Wei Lin, Jinyan Zhao, Liangpu Zheng, Hongzhi Ye, Lianming Liao, Jian D. Jiedu Xiaozheng Yin decoction inhibits hepatoma cell proliferation by inducing apoptosis via the mitochondrial-mediated pathway. Molecular medicine reports. vol 12. issue 2. 2016-03-16. PMID:25936398. |
furthermore, ee-jxy induced hepg2 cell apoptosis, as demonstrated by a loss of plasma membrane asymmetry and externalization of phosphatidylserine, collapse of mitochondrial membrane potential, activation of caspase-9 and caspase-3, and an increased ratio of pro-apoptotic bax to anti-apoptotic bcl-2. |
2016-03-16 |
2023-08-13 |
mouse |
| Hannah M Hankins, Ryan D Baldridge, Peng Xu, Todd R Graha. Role of flippases, scramblases and transfer proteins in phosphatidylserine subcellular distribution. Traffic (Copenhagen, Denmark). vol 16. issue 1. 2016-01-26. PMID:25284293. |
this asymmetric ps distribution can be used as a signaling device by the regulated activation of scramblases, which rapidly expose ps on the extracellular leaflet and play important roles in blood clotting and apoptosis. |
2016-01-26 |
2023-08-13 |
Not clear |
| Salvatrice Calabrò, Kousi Alzoubi, Rosi Bissinger, Kashif Jilani, Caterina Faggio, Florian Lan. Enhanced eryptosis following juglone exposure. Basic & clinical pharmacology & toxicology. vol 116. issue 6. 2016-01-26. PMID:25348830. |
in analogy to apoptosis of nucleated cells, erythrocytes may enter eryptosis, a suicidal death characterized by cell shrinkage and breakdown of phosphatidylserine asymmetry of the cell membrane with phosphatidylserine exposure at the erythrocyte surface. |
2016-01-26 |
2023-08-13 |
human |
| Dan Hong, Hai-Chao Gao, Xiang Wang, Ling-Fang Li, Chuan-Chang Li, Ying Luo, Kang-Kai Wang, Yong-Ping Bai, Guo-Gang Zhan. Asymmetric dimethylarginine triggers macrophage apoptosis via the endoplasmic reticulum stress pathway. Molecular and cellular biochemistry. vol 398. issue 1-2. 2016-01-15. PMID:25209804. |
asymmetric dimethylarginine triggers macrophage apoptosis via the endoplasmic reticulum stress pathway. |
2016-01-15 |
2023-08-13 |
Not clear |
| Dan Hong, Hai-Chao Gao, Xiang Wang, Ling-Fang Li, Chuan-Chang Li, Ying Luo, Kang-Kai Wang, Yong-Ping Bai, Guo-Gang Zhan. Asymmetric dimethylarginine triggers macrophage apoptosis via the endoplasmic reticulum stress pathway. Molecular and cellular biochemistry. vol 398. issue 1-2. 2016-01-15. PMID:25209804. |
asymmetric dimethylarginine (adma), an endogenous inhibitor of nitric oxide synthase (nos), is emerging as a key contributing factor in atherogenesis, a process in turn known to involve macrophage apoptosis. |
2016-01-15 |
2023-08-13 |
Not clear |
| Noel M Rysavy, Lori M N Shimoda, Alyssa M Dixon, Mark Speck, Alexander J Stokes, Helen Turner, Eric Y Umemot. Beyond apoptosis: the mechanism and function of phosphatidylserine asymmetry in the membrane of activating mast cells. Bioarchitecture. vol 4. issue 4-5. 2015-10-14. PMID:25759911. |
beyond apoptosis: the mechanism and function of phosphatidylserine asymmetry in the membrane of activating mast cells. |
2015-10-14 |
2023-08-13 |
Not clear |
| Noel M Rysavy, Lori M N Shimoda, Alyssa M Dixon, Mark Speck, Alexander J Stokes, Helen Turner, Eric Y Umemot. Beyond apoptosis: the mechanism and function of phosphatidylserine asymmetry in the membrane of activating mast cells. Bioarchitecture. vol 4. issue 4-5. 2015-10-14. PMID:25759911. |
loss of plasma membrane asymmetry is a hallmark of apoptosis, but lipid bilayer asymmetry and loss of asymmetry can contribute to numerous cellular functions and responses that are independent of programmed cell death. |
2015-10-14 |
2023-08-13 |
Not clear |
| Dong Liu, Xue-Jun Sun, Chao Zhang, Sai He, Jun-Kai Du, Xiong-Wei Huo, Jian-Bao Zheng, Shi-Yun Zhang, Yuan-Fuz Zhang, Yi-Zhuang Xu, Jin-Guang W. [Label-free monitoring 5-FU induced SW 620 cells apoptosis using FTIR microspectroscopy]. Guang pu xue yu guang pu fen xi = Guang pu. vol 33. issue 12. 2015-07-08. PMID:24611364. |
(3) 1 240 cm-1 is mainly due to the asymmetric stretching modes of phosphodiester groups shifting to higher wave number, illustrating that nucleic acid conformation was changed in apoptosis cells. |
2015-07-08 |
2023-08-12 |
Not clear |
| Tatyana Luzyanina, Jovana Cupovic, Burkhard Ludewig, Gennady Bocharo. Mathematical models for CFSE labelled lymphocyte dynamics: asymmetry and time-lag in division. Journal of mathematical biology. vol 69. issue 6-7. 2015-06-25. PMID:24337680. |
the model is used to estimate fundamental parameters such as activation rate, duration of the cell cycle, apoptosis rate, cfse decay rate and asymmetry factor in cell division of monoclonal t cells during cognate interaction with dendritic cells. |
2015-06-25 |
2023-08-12 |
Not clear |
| Tong Lu, Weimin Yang, Zhihua Wang, Zhiquan Hu, Xing Zeng, Chunguang Yang, Ye Wang, Yong Zhang, Fan Li, Zhuo Liu, Dongbiao Wang, Zhangqun Y. Knockdown of glucose-regulated protein 78/binding immunoglobulin heavy chain protein expression by asymmetric small interfering RNA induces apoptosis in prostate cancer cells and attenuates migratory capability. Molecular medicine reports. vol 11. issue 1. 2015-06-25. PMID:25338653. |
knockdown of glucose-regulated protein 78/binding immunoglobulin heavy chain protein expression by asymmetric small interfering rna induces apoptosis in prostate cancer cells and attenuates migratory capability. |
2015-06-25 |
2023-08-13 |
human |
| Tong Lu, Weimin Yang, Zhihua Wang, Zhiquan Hu, Xing Zeng, Chunguang Yang, Ye Wang, Yong Zhang, Fan Li, Zhuo Liu, Dongbiao Wang, Zhangqun Y. Knockdown of glucose-regulated protein 78/binding immunoglobulin heavy chain protein expression by asymmetric small interfering RNA induces apoptosis in prostate cancer cells and attenuates migratory capability. Molecular medicine reports. vol 11. issue 1. 2015-06-25. PMID:25338653. |
in conclusion, knockdown of grp78/bip expression with asymmetric sirna led to increased prostate cancer cell apoptosis and reduced cellular migration. |
2015-06-25 |
2023-08-13 |
human |
| Kerri-Ann Norton, Aleksander S Pope. An agent-based model of cancer stem cell initiated avascular tumour growth and metastasis: the effect of seeding frequency and location. Journal of the Royal Society, Interface. vol 11. issue 100. 2015-05-12. PMID:25185580. |
the model includes several important cellular features such as stem cell symmetric and asymmetric division, migration, cellular quiescence, senescence, apoptosis and cell division cycles. |
2015-05-12 |
2023-08-13 |
Not clear |
| Janin Jacobi, Elisabeth Lang, Rosi Bissinger, Leonie Frauenfeld, Paola Modicano, Caterina Faggio, Majed Abed, Florian Lan. Stimulation of erythrocyte cell membrane scrambling by mitotane. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 33. issue 5. 2015-04-14. PMID:24854840. |
in analogy to apoptosis of nucleated cells, eryptosis is the suicidal death of erythrocytes, which is typically paralleled by cell shrinkage and breakdown of cell membrane phosphatidylserine asymmetry with subsequent phosphatidylserine exposure at the erythrocyte surface. |
2015-04-14 |
2023-08-13 |
human |