| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vannarut Satitpitakul, Zhongmou Sun, Kunal Suri, Afsaneh Amouzegar, Kishore R Katikireddy, Ula V Jurkunas, Ahmad Kheirkhah, Reza Dan. Vasoactive Intestinal Peptide Promotes Corneal Allograft Survival. The American journal of pathology. vol 188. issue 9. 2019-08-23. PMID:30097165. |
the neuropeptide vasoactive intestinal peptide (vip) improves cenc integrity during donor cornea tissue storage and protects cencs against oxidative stress-induced apoptosis. |
2019-08-23 |
2023-08-13 |
mouse |
| Wenzhen An, Ying Zhang, Xuan Zhang, Kang Li, Yujun Kang, Shahnaz Akhtar, Xueli Sha, Lan Ga. Ocular toxicity of reduced graphene oxide or graphene oxide exposure in mouse eyes. Experimental eye research. vol 174. 2019-02-11. PMID:29803558. |
the findings show that short-term repeated go exposure can cause obvious intraocular inflammation, an incrassated corneal stromal layer, cell apoptosis in the cornea, iris neovascularization and significant cytotoxicity of rat corneal epithelial cells (rcecs), while rgo causes no significant ocular toxicity in mice. |
2019-02-11 |
2023-08-13 |
mouse |
| S Altan, H Sağsöz, Z Oğurta. Topical dimethyl sulfoxide inhibits corneal neovascularization and stimulates corneal repair in rabbits following acid burn. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 92. issue 8. 2019-02-08. PMID:29233043. |
we suggest that vegi in the endothelial cells of neovascularized cornea may act as a signaling protein that promotes balance between cell proliferation and apoptosis. |
2019-02-08 |
2023-08-13 |
Not clear |
| Paramananda Saikia, Carla S Medeiros, Shanmugapriya Thangavadivel, Steven E Wilso. Basement membranes in the cornea and other organs that commonly develop fibrosis. Cell and tissue research. vol 374. issue 3. 2019-01-14. PMID:30284084. |
an example of this is the critical role of both the epithelial basement membrane and descemet's basement membrane in the cornea in modulating myofibroblast development and fibrosis, as well as myofibroblast apoptosis and the resolution of fibrosis. |
2019-01-14 |
2023-08-13 |
Not clear |
| Carla S Medeiros, Luciana Lassance, Paramananda Saikia, Marcony R Santhiago, Steven E Wilso. Posterior stromal cell apoptosis triggered by mechanical endothelial injury and basement membrane component nidogen-1 production in the cornea. Experimental eye research. vol 172. 2018-12-31. PMID:29596850. |
posterior stromal cell apoptosis triggered by mechanical endothelial injury and basement membrane component nidogen-1 production in the cornea. |
2018-12-31 |
2023-08-13 |
Not clear |
| Carla S Medeiros, Luciana Lassance, Paramananda Saikia, Marcony R Santhiago, Steven E Wilso. Posterior stromal cell apoptosis triggered by mechanical endothelial injury and basement membrane component nidogen-1 production in the cornea. Experimental eye research. vol 172. 2018-12-31. PMID:29596850. |
this study was performed to determine whether cells in the posterior stroma undergo apoptosis in response to endothelial cell injury and to determine whether basement membrane component nidogen-1 was present in the cornea. |
2018-12-31 |
2023-08-13 |
Not clear |
| Jianying Gong, Linan Guan, Pei Tian, Chao Li, Yi Zhan. Rho Kinase Type 1 (ROCK1) Promotes Lipopolysaccharide-induced Inflammation in Corneal Epithelial Cells by Activating Toll-Like Receptor 4 (TLR4)-Mediated Signaling. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-10-01. PMID:29804125. |
conclusions lps-induced inflammation and apoptosis in hcecs depended on the function of rock1, inhibition of which would attenuate impairments on cornea cells due to lps. |
2018-10-01 |
2023-08-13 |
human |
| Jin Hyoung Park, Soon-Suk Kang, Jae Yong Kim, Hungwon Tcha. Nerve Growth Factor Attenuates Apoptosis and Inflammation in the Diabetic Cornea. Investigative ophthalmology & visual science. vol 57. issue 15. 2017-06-15. PMID:27978558. |
nerve growth factor attenuates apoptosis and inflammation in the diabetic cornea. |
2017-06-15 |
2023-08-13 |
Not clear |
| Jin Hyoung Park, Soon-Suk Kang, Jae Yong Kim, Hungwon Tcha. Nerve Growth Factor Attenuates Apoptosis and Inflammation in the Diabetic Cornea. Investigative ophthalmology & visual science. vol 57. issue 15. 2017-06-15. PMID:27978558. |
to examine the effects of nerve growth factor (ngf) on apoptosis and inflammation in the diabetic cornea. |
2017-06-15 |
2023-08-13 |
Not clear |
| Ling Wang, Sheyla González, Wei Dai, Sophie Deng, Luo L. Effect of Hypoxia-regulated Polo-like Kinase 3 (Plk3) on Human Limbal Stem Cell Differentiation. The Journal of biological chemistry. vol 291. issue 32. 2017-05-05. PMID:27281822. |
hypoxic conditions in the cornea affect epithelial function by activating polo-like kinase 3 (plk3) signaling and the c-jun·ap-1 transcription complex, resulting in apoptosis of corneal epithelial cells. |
2017-05-05 |
2023-08-13 |
mouse |
| Edwin H A Allen, David G Courtney, Sarah D Atkinson, Johnny E Moore, Laura Mairs, Ebbe Toftgaard Poulsen, Davide Schiroli, Eleonora Maurizi, Christian Cole, Robyn P Hickerson, John James, Helen Murgatroyd, Frances J D Smith, Carrie MacEwen, Jan J Enghild, M Andrew Nesbit, Deena M Leslie Pedrioli, W H Irwin McLean, C B Tara Moor. Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy. Human molecular genetics. vol 25. issue 6. 2016-12-15. PMID:26758872. |
corneal epithelial cell apoptosis was increased 17-fold in the mutant cornea, compared with the wild-type (p < 0.001). |
2016-12-15 |
2023-08-13 |
mouse |
| Andre A M Torricelli, Abirami Santhanam, Jiahui Wu, Vivek Singh, Steven E Wilso. The corneal fibrosis response to epithelial-stromal injury. Experimental eye research. vol 142. 2016-04-18. PMID:26675407. |
several factors are associated with myofibroblast generation and haze development after prk surgery in rabbits, a reproducible model of scarring, including the amount of tissue ablated, which may relate to the extent of keratocyte apoptosis in the early response to injury, irregularity of stromal surface after surgery, and changes in corneal stromal proteoglycans, but normal regeneration of the epithelial basement membrane (ebm) appears to be a critical factor determining whether a cornea heals with relative transparency or vision-limiting stromal opacity. |
2016-04-18 |
2023-08-13 |
Not clear |
| Martin Kronschläger, Nooshin Talebizadeh, Zhaohua Yu, Linda Maren Meyer, Stefan Löfgre. Apoptosis in Rat Cornea After In Vivo Exposure to Ultraviolet Radiation at 300 nm. Cornea. vol 34. issue 8. 2016-02-05. PMID:26075458. |
apoptosis in rat cornea after in vivo exposure to ultraviolet radiation at 300 nm. |
2016-02-05 |
2023-08-13 |
rat |
| Martin Kronschläger, Nooshin Talebizadeh, Zhaohua Yu, Linda Maren Meyer, Stefan Löfgre. Apoptosis in Rat Cornea After In Vivo Exposure to Ultraviolet Radiation at 300 nm. Cornea. vol 34. issue 8. 2016-02-05. PMID:26075458. |
the purpose of the study was to determine the time evolution of apoptosis in the cornea after in vivo exposure to 300-nm uvr. |
2016-02-05 |
2023-08-13 |
rat |
| Yoshinori Oie, Motohiro Kamei, Naoyuki Maeda, Takashi Fujikado, Kohji Nishid. Development of the Department of Ophthalmology at Osaka University. Asia-Pacific journal of ophthalmology (Philadelphia, Pa.). vol 2. issue 3. 2015-06-26. PMID:26108105. |
their advanced clinical practice performs translational research on the regenerative medicine of the cornea, artificial retina, diagnostic instruments and tools, apoptosis of photoreceptors, and drug discovery. |
2015-06-26 |
2023-08-13 |
Not clear |
| Christophe Baudouin, Pasquale Aragona, Elisabeth M Messmer, Alan Tomlinson, Margarita Calonge, Kostas G Boboridis, Yonca A Akova, Gerd Geerling, Marc Labetoulle, Maurizio Roland. Role of hyperosmolarity in the pathogenesis and management of dry eye disease: proceedings of the OCEAN group meeting. The ocular surface. vol 11. issue 4. 2014-06-10. PMID:24112228. |
tear hyperosmolarity gives rise to morphological changes such as apoptosis of cells of the conjunctiva and cornea, and triggers inflammatory cascades that contribute to further cell death, including loss of mucin-producing goblet cells. |
2014-06-10 |
2023-08-12 |
Not clear |
| E Anitua, F Muruzabal, I Alcalde, J Merayo-Lloves, G Oriv. Plasma rich in growth factors (PRGF-Endoret) stimulates corneal wound healing and reduces haze formation after PRK surgery. Experimental eye research. vol 115. 2013-12-13. PMID:23872360. |
immunofluorescence was used to assess cellular proliferation, apoptosis and myofibroblast transformation in the mouse cornea. |
2013-12-13 |
2023-08-12 |
mouse |
| Julia Tau, Priscila Novaes, Monique Matsuda, Deborah R Tasat, Paulo H Saldiva, Alejandro Berr. Diesel exhaust particles selectively induce both proinflammatory cytokines and mucin production in cornea and conjunctiva human cell lines. Investigative ophthalmology & visual science. vol 54. issue 7. 2013-09-19. PMID:23722391. |
to evaluate the effect of diesel exhaust particles (dep) on the viability, proliferation, apoptosis, secretion of cytokines (il-6, il-8, and tnf-α), and mucin gene transcription (muc1, muc5ac, and muc16) in human epithelial cells of the cornea (hcle) and conjunctiva (ioba-nhc). |
2013-09-19 |
2023-08-12 |
human |
| Piotr Czarny, Ewelina Kasprzak, Mariusz Wielgorski, Monika Udziela, Beata Markiewicz, Janusz Blasiak, Jerzy Szaflik, Jacek P Szafli. DNA damage and repair in Fuchs endothelial corneal dystrophy. Molecular biology reports. vol 40. issue 4. 2013-09-04. PMID:23275192. |
the disease is characterized by the presence of extracellular deposits called "cornea guttata", apoptosis of corneal endothelial cells, dysfunction of descement's membrane and corneal edema. |
2013-09-04 |
2023-08-12 |
Not clear |
| Ming-Ju Tsai, Ya-Ling Hsu, Kwou-Yeung Wu, Rei-Cheng Yang, Yi-Jen Chen, Hsin-Su Yu, Po-Lin Ku. Heat effect induces production of inflammatory cytokines through heat shock protein 90 pathway in cornea cells. Current eye research. vol 38. issue 4. 2013-09-03. PMID:23330884. |
our previous study has demonstrated that heat shock (42 °c) induces apoptosis of statens seruminstitut rabbit cornea (sirc) cells. |
2013-09-03 |
2023-08-12 |
rabbit |