| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eric Pearlman, Yan Sun, Sanhita Roy, Mausita Karmakar, Amy G Hise, Loretta Szczotka-Flynn, Mahmoud Ghannoum, Holly R Chinnery, Paul G McMenamin, Arne Rietsc. Host defense at the ocular surface. International reviews of immunology. vol 32. issue 1. 2013-07-12. PMID:23360155. |
further, as the p. aeruginosa type iii secretion system (t3ss) also plays a critical role in disease pathogenesis by inducing neutrophil apoptosis and facilitating bacterial growth in the cornea, t3ss exotoxins are additional targets for therapy for p. aeruginosa keratitis. |
2013-07-12 |
2023-08-12 |
Not clear |
| Matteo Lulli, Ewa Witort, Laura Papucci, Eugenio Torre, Christian Schipani, Christian Bergamini, Massimo Dal Monte, Sergio Capacciol. Coenzyme Q10 instilled as eye drops on the cornea reaches the retina and protects retinal layers from apoptosis in a mouse model of kainate-induced retinal damage. Investigative ophthalmology & visual science. vol 53. issue 13. 2013-02-14. PMID:23154463. |
coenzyme q10 instilled as eye drops on the cornea reaches the retina and protects retinal layers from apoptosis in a mouse model of kainate-induced retinal damage. |
2013-02-14 |
2023-08-12 |
mouse |
| Matteo Lulli, Ewa Witort, Laura Papucci, Eugenio Torre, Christian Schipani, Christian Bergamini, Massimo Dal Monte, Sergio Capacciol. Coenzyme Q10 instilled as eye drops on the cornea reaches the retina and protects retinal layers from apoptosis in a mouse model of kainate-induced retinal damage. Investigative ophthalmology & visual science. vol 53. issue 13. 2013-02-14. PMID:23154463. |
to evaluate if coenzyme q10 (coq10) can protect retinal ganglion cells (rgcs) from apoptosis and, when instilled as eye drops on the cornea, if it can reach the retina and exert its antiapoptotic activity in this area in a mouse model of kainate (ka)-induced retinal damage. |
2013-02-14 |
2023-08-12 |
mouse |
| Matteo Lulli, Ewa Witort, Laura Papucci, Eugenio Torre, Nicola Schiavone, Massimo Dal Monte, Sergio Capacciol. Coenzyme Q10 protects retinal cells from apoptosis induced by radiation in vitro and in vivo. Journal of radiation research. vol 53. issue 5. 2013-01-25. PMID:22843363. |
the aim of this study was to evaluate whether coq10 can protect cultured retinal cells and the retinas of rats from radiation-induced apoptosis, if instilled as eye drops in the cornea. |
2013-01-25 |
2023-08-12 |
rat |
| Matteo Lulli, Ewa Witort, Laura Papucci, Eugenio Torre, Nicola Schiavone, Massimo Dal Monte, Sergio Capacciol. Coenzyme Q10 protects retinal cells from apoptosis induced by radiation in vitro and in vivo. Journal of radiation research. vol 53. issue 5. 2013-01-25. PMID:22843363. |
in the rat, coq10, even when applied as eye drops on the cornea, protected all retina layers from uvr-induced apoptosis. |
2013-01-25 |
2023-08-12 |
rat |
| Matteo Lulli, Ewa Witort, Laura Papucci, Eugenio Torre, Nicola Schiavone, Massimo Dal Monte, Sergio Capacciol. Coenzyme Q10 protects retinal cells from apoptosis induced by radiation in vitro and in vivo. Journal of radiation research. vol 53. issue 5. 2013-01-25. PMID:22843363. |
the ability of coq10 to protect retinal cells from radiation-induced apoptosis following its instillation on the cornea suggests the possibility for coq10 eye drops to become a future therapeutic countermeasure for radiation-induced retinal lesions. |
2013-01-25 |
2023-08-12 |
rat |
| Pierre Fournie, Stéphane Galiacy, Marie-Laure Ranty, Isabelle Rico-Lattes, François Malecaze, Jean-Claude Quinty. Sphingosine-1 phosphate prevents ethanol-induced corneal epithelial apoptosis. Indian journal of ophthalmology. vol 60. issue 2. 2012-07-24. PMID:22446906. |
apoptosis is a programmed cell death in multicellular organisms, found in a wide variety of conditions, including inflammatory process, everywhere in the body, including the cornea and conjunctiva. |
2012-07-24 |
2023-08-12 |
Not clear |
| Debra J Warejcka, Malathi Narayan, Sally S Twinin. Maspin increases extracellular plasminogen activator activity associated with corneal fibroblasts and myofibroblasts. Experimental eye research. vol 93. issue 5. 2012-02-03. PMID:21810423. |
when the cornea is wounded, the quiescent stromal keratocytes underlying the wound undergo apoptosis and cells adjacent to this apoptotic area convert to fibroblasts or myofibroblasts. |
2012-02-03 |
2023-08-12 |
Not clear |
| Nan Gao, Jia Yin, Gi Sang Yoon, Qing-Sheng Mi, Fu-Shin X Y. Dendritic cell-epithelium interplay is a determinant factor for corneal epithelial wound repair. The American journal of pathology. vol 179. issue 5. 2012-01-24. PMID:21924232. |
on the other hand, dc depletion resulted in suppressed epithelial akt activation, increased cell apoptosis, and decreased polymorphonuclear leukocyte infiltration in the healing cornea. |
2012-01-24 |
2023-08-12 |
mouse |
| Ya-Ling Hsu, Hsin-Su Yu, Hsien-Chung Lin, Kwou-Yeung Wu, Rei-Cheng Yang, Po-Lin Ku. Heat shock induces apoptosis through reactive oxygen species involving mitochondrial and death receptor pathways in corneal cells. Experimental eye research. vol 93. issue 4. 2012-01-16. PMID:21712031. |
taken together, these findings suggest a critical role for ros involving mitochondrial and death receptor pathways in heat shock-mediated apoptosis of cornea cells. |
2012-01-16 |
2023-08-12 |
rabbit |
| Yujin Zhang, Winston W-Y Kao, Emanuele Pelosi, David Schlessinger, Chia-Yang Li. Notch gain of function in mouse periocular mesenchyme downregulates FoxL2 and impairs eyelid levator muscle formation, leading to congenital blepharophimosis. Journal of cell science. vol 124. issue Pt 15. 2011-12-14. PMID:21730020. |
compound transgenic mice overexpressing the notch1 intracellular domain (n1-icd) in pomcs (pomc(n1-icd)) showed relatively minor effects on the cornea, but increased cell apoptosis and decreased cell proliferation during eyelid morphogenesis. |
2011-12-14 |
2023-08-12 |
mouse |
| Heather Chandle. Ultraviolet absorption by contact lenses and the significance on the ocular anterior segment. Eye & contact lens. vol 37. issue 4. 2011-12-06. PMID:21646978. |
dna damage, apoptosis, and altered protease expression are all examples of harmful changes that can occur within the cornea after irradiation. |
2011-12-06 |
2023-08-12 |
Not clear |
| Mirko R Jankov Ii, Vesna Jovanovic, Ljubisa Nikolic, Jonathan C Lake, Georgos Kymionis, Efekan Coskunseve. Corneal collagen cross-linking. Middle East African journal of ophthalmology. vol 17. issue 1. 2011-07-14. PMID:20543933. |
corneal collagen cross-linking (cxl) with riboflavin and ultraviolet-a (uva) is a new technique of corneal tissue strengthening by using riboflavin as a photosensitizer and uva to increase the formation of intra and interfibrillar covalent bonds by photosensitized oxidation.keratocyte apoptosis in the anterior segment of the corneal stroma all the way down to a depth of about 300 microns has been described and a demarcation line between the treated and untreated cornea has been clearly shown. |
2011-07-14 |
2023-08-12 |
Not clear |
| Gabriel Sosne, Ping Qiu, Michelle Kurpakus-Wheate. Thymosin beta 4: A novel corneal wound healing and anti-inflammatory agent. Clinical ophthalmology (Auckland, N.Z.). vol 1. issue 3. 2011-05-10. PMID:19668473. |
in cornea, as in other tissues, tbeta(4) promotes cell migration and wound healing, has anti-inflammatory properties, and suppresses apoptosis. |
2011-05-10 |
2023-08-12 |
Not clear |
| Yaqin Liu, Zhaoxin Jiang, Qianying Gao, Jian Ge, Jiajia Chen, Xianwu Cao, Qingxiang Shen, Ping M. Technical standards of a foldable capsular vitreous body in terms of mechanical, optical, and biocompatible properties. Artificial organs. vol 34. issue 10. 2011-02-10. PMID:20618225. |
the biocompatible properties are shown in the stable extracts experiment, no significant fever, good genetic safety, and no structural abnormality or apoptosis in the cornea, ciliary body, and retina over a 6-month observation period. |
2011-02-10 |
2023-08-12 |
rabbit |
| Yang Zhou, Chuan-fu Wang, Tao Jian. [Expression of apoptosis related genes and changes of lacrimal functions in main lacrimal gland extirpation xerophthalmia model]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology. vol 43. issue 1. 2010-11-04. PMID:17442157. |
to establish a main lacrimal gland extirpation xerophthalmia model and to study the relationship between expression of apoptosis genes in various ocular surface cells (cornea and conjunctiva epithelium cells and meibomian cells) and ocular surface sicca as well as tissue damages in this model. |
2010-11-04 |
2023-08-12 |
Not clear |
| F L Barbosa, S S Chaurasia, H Kaur, F W de Medeiros, V Agrawal, S E Wilso. Stromal interleukin-1 expression in the cornea after haze-associated injury. Experimental eye research. vol 91. issue 3. 2010-09-20. PMID:20603114. |
this study demonstrates that sma- cells such as corneal fibroblasts, keratocytes, or inflammatory cells may produce il-1alpha and/or il-1beta that could act in paracrine fashion to regulate myofibroblast apoptosis--especially in the region where there is haze in the cornea after prk was performed and sma+ myofibroblasts are present at higher density. |
2010-09-20 |
2023-08-12 |
Not clear |
| Renato Ambrósio, Newton Kara-José, Steven E Wilso. Early keratocyte apoptosis after epithelial scrape injury in the human cornea. Experimental eye research. vol 89. issue 4. 2010-01-27. PMID:19523947. |
early keratocyte apoptosis after epithelial scrape injury in the human cornea. |
2010-01-27 |
2023-08-12 |
mouse |
| Renato Ambrósio, Newton Kara-José, Steven E Wilso. Early keratocyte apoptosis after epithelial scrape injury in the human cornea. Experimental eye research. vol 89. issue 4. 2010-01-27. PMID:19523947. |
anterior keratocyte apoptosis was detected in the three corneas that had epithelial scrape injury, but not in the control unwounded cornea. |
2010-01-27 |
2023-08-12 |
mouse |
| Teri M S Greiling, John I Clar. Early lens development in the zebrafish: a three-dimensional time-lapse analysis. Developmental dynamics : an official publication of the American Association of Anatomists. vol 238. issue 9. 2009-11-13. PMID:19504455. |
a lens vesicle was not observed and apoptosis was not a major factor in separation of the lens from the future cornea. |
2009-11-13 |
2023-08-12 |
zebrafish |