| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marlen Alexis Gonzalez-Reyna, Ricardo Aguilar-Villalva, José López, Angelina Rodríguez-Torres, Gustavo A Molina, Karla Juarez-Moreno, Rodrigo Esparza, Miriam Esteve. Nanoarchitectonics of an acetogenin-enriched nanosystem mediated by an aqueous extract of Nanotechnology. 2024-05-03. PMID:38701760. |
nanoarchitectonics of an acetogenin-enriched nanosystem mediated by an aqueous extract of for the first time, this study shows the nanoarchitectonic process to obtain an acetogenin-enriched nanosystem (aunps-ac) using an aqueous extract from annona cherimola mill (acm) composed of gold nanoparticles embedded in an organic matrix that acts as stabilizing agent and presents anti-inflammatory activity and cytotoxical effect against hepg2 cell line, promoting apoptosis. |
2024-05-03 |
2024-05-06 |
Not clear |
| Bin Hu, Gongwen D. OSTF1 knockdown mitigates IL-1β-induced chondrocyte injury via inhibiting the NF-κB signaling pathway. Heliyon. vol 10. issue 9. 2024-05-03. PMID:38699012. |
next, the role of ostf1 in interleukin-1β (il-1β)-induced chondrocyte apoptosis, inflammation and extracellular matrix degradation was explored through loss of function assays. |
2024-05-03 |
2024-05-05 |
rat |
| Linhe Lu, Yalan Shao, Nisha Wang, Xiang Xiong, Mengen Zhai, Jiayou Tang, Yang Liu, Jian Yang, Lifang Yan. Follistatin-like protein 1 attenuates doxorubicin-induced cardiomyopathy by inhibiting MsrB2-mediated mitophagy. Molecular and cellular biochemistry. 2024-05-02. PMID:38696001. |
fstl1 treatment attenuated dox-induced cardiac dysfunction, cardiac fibrosis, and cellular apoptosis by inhibiting excess mitochondrial matrix protein methionine sulfoxide reductase b2 (msrb2)-mediated mitophagy. |
2024-05-02 |
2024-05-04 |
Not clear |
| Yuanchi Huang, Wenjie Pan, Jianbing M. SKP2-mediated ubiquitination and degradation of KLF11 promotes osteoarthritis via modulation of JMJD3/NOTCH1 pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 38. issue 9. 2024-05-01. PMID:38690715. |
skp2/jmjd3 silencing or klf11 overexpression repressed apoptosis and extracellular matrix (ecm) degradation in chondrocytes. |
2024-05-01 |
2024-05-03 |
rat |
| Ke-Xun Yu, Wei-Jie Yuan, Hui-Zhen Wang, Yong-Xiang L. Extracellular matrix stiffness and tumor-associated macrophage polarization: new fields affecting immune exclusion. Cancer immunology, immunotherapy : CII. vol 73. issue 6. 2024-05-01. PMID:38693304. |
recent research evidence have shown that the extracellular matrix plays an important role in angiogenesis, cell proliferation, migration, immunosuppression, apoptosis, metabolism, and resistance to chemotherapeutic by the alterations toward both secretion and degradation. |
2024-05-01 |
2024-05-04 |
Not clear |
| Nak-Eun Choi, Si-Chan Park, In-Ryoung Ki. Tivozanib-induced activation of the mitochondrial apoptotic pathway and suppression of epithelial-to-mesenchymal transition in oral squamous cell carcinoma. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 28. issue 3. 2024-04-29. PMID:38682168. |
this was accompanied by the suppression of bcl-2, a reduction in matrix metalloproteinase levels, and the induction of intrinsic pathway-mediated apoptosis. |
2024-04-29 |
2024-05-01 |
Not clear |
| Byung Chul Jung, Sung-Hun Woo, Sung Hoon Kim, Yoon Suk Ki. Parkin Enhances Gefitinib-induced Anoikis in HeLa Cervical Cancer Cells. Anticancer research. vol 44. issue 5. 2024-04-27. PMID:38677741. |
gefitinib exhibits anticancer activity against cervical cancer cells via anoikis, a type of apoptosis induced by cell detachment from the extracellular matrix. |
2024-04-27 |
2024-04-30 |
human |
| Zengguang Wang, Zhenglin Dong, Yiming Li, Xin Jiao, Yihao Liu, Hanwen Chang, Yaokai Ga. Verapamil Attenuates the Severity of Tendinopathy by Mitigating Mitochondrial Dysfunction through the Activation of the Nrf2/HO-1 Pathway. Biomedicines. vol 12. issue 4. 2024-04-27. PMID:38672259. |
the in vitro findings highlighted the remarkable ability of verapamil to attenuate extracellular matrix degradation and apoptosis triggered by inflammation in tenocytes stimulated by il-1β. |
2024-04-27 |
2024-04-29 |
rat |
| Weilu Gao, Rui Liu, Keke Huang, Wenhan Fu, Anquan Wang, Gongwen Du, Hao Tang, Li Yin, Zongsheng S Yi. CHMP5 attenuates osteoarthritis via inhibiting chondrocyte apoptosis and extracellular matrix degradation: involvement of NF-κB pathway. Molecular medicine (Cambridge, Mass.). vol 30. issue 1. 2024-04-26. PMID:38664616. |
chmp5 attenuates osteoarthritis via inhibiting chondrocyte apoptosis and extracellular matrix degradation: involvement of nf-κb pathway. |
2024-04-26 |
2024-04-28 |
Not clear |
| Weilu Gao, Rui Liu, Keke Huang, Wenhan Fu, Anquan Wang, Gongwen Du, Hao Tang, Li Yin, Zongsheng S Yi. CHMP5 attenuates osteoarthritis via inhibiting chondrocyte apoptosis and extracellular matrix degradation: involvement of NF-κB pathway. Molecular medicine (Cambridge, Mass.). vol 30. issue 1. 2024-04-26. PMID:38664616. |
osteoarthritis (oa), the most common joint disease, is linked with chondrocyte apoptosis and extracellular matrix (ecm) degradation. |
2024-04-26 |
2024-04-28 |
Not clear |
| P G Roopashree, Shilpa S Shetty, Vijith Vittal Shetty, P C Suhasini, Kumari N Sucheth. Inhibitory effects of medium-chain fatty acids on the proliferation of human breast cancer cells via suppression of Akt/mTOR pathway and modulating the Bcl-2 family protein. Journal of cellular biochemistry. 2024-04-26. PMID:38666486. |
to investigate the apoptosis-inducing effect of mcfas in breast cancer cells, cell viability assay, colony formation assay, cell migration assay, cell invasion assay, nuclear morphology, cell cycle assay, intracellular reactive oxygen species (ros), matrix metalloproteinase (mmp), apoptosis, rt-qpcr analysis, and western blot analysis were performed. |
2024-04-26 |
2024-04-28 |
human |
| Binbin Hu, Guihong Liu, Kejia Zhao, Gao Zhan. Diversity of extracellular HSP70 in cancer: advancing from a molecular biomarker to a novel therapeutic target. Frontiers in oncology. vol 14. 2024-04-22. PMID:38646439. |
ehsp70 is involved in a broad range of cancer-related events, including cell proliferation and apoptosis, extracellular matrix (ecm) remodeling, epithelial-mesenchymal transition (emt), angiogenesis, and immune response. |
2024-04-22 |
2024-04-24 |
Not clear |
| Sung Su Park, Wonjun Cho, Do Su Lim, Hyeon Ji Gwon, Sung Woo Choi, A M Abd El-Aty, Hacı Ahmet Aydemir, Ji Hoon Jeong, Tae Woo Jun. AMPK/autophagy-mediated alleviation of tendinopathy by IL-38: A novel strategy for the treatment of obesity-related tendinopathy. Tissue & cell. vol 88. 2024-04-21. PMID:38643674. |
these results suggest that il-38 alleviates er stress through the ampk/autophagy pathway, thereby reducing apoptosis and preventing extracellular matrix (ecm) degradation in tenocytes under hyperlipidemic conditions. |
2024-04-21 |
2024-04-24 |
human |
| Mengwei Li, Xiaojun Yu, Xin Chen, Yongqiao Jiang, Yunqian Zeng, Ranyue Ren, Mingbo Nie, Ziyang Zhang, Yuan Bao, Hao Kan. Genkwanin alleviates intervertebral disc degeneration via regulating ITGA2/PI3K/AKT pathway and inhibiting apoptosis and senescence. International immunopharmacology. vol 133. 2024-04-19. PMID:38640717. |
in conclusion, this study suggest that genkwanin inhibits inflammation in nucleus pulposus cells, promotes extracellular matrix remodeling, suppresses cellular senescence and apoptosis, through the itga2/pi3k/akt, nf-κb and mapk signaling pathways. |
2024-04-19 |
2024-04-22 |
rat |
| Xiang-Ning He, Wei-Dan Jiang, Pei Wu, Yang Liu, Hong-Mei Ren, Xiao-Wan Jin, Sheng-Yao Kuang, Ling Tang, Shu-Wei Li, Lin Feng, Xiao-Qiu Zho. Aflatoxin B1 inhibited the development of primary myoblasts of grass carp (Ctenopharyngodon idella) by degrading extracellular matrix. Ecotoxicology and environmental safety. vol 276. 2024-04-16. PMID:38626608. |
as a result, our findings suggested that afb1 damaged the cell morphology, induced oxidative damage and apoptosis, degraded ecm components, in turn inhibiting myoblast development by activating the p38mapk/urokinase-type plasminogen activator (upa)/matrix metalloproteinase (mmps)/extracellular matrix (ecm) signaling pathway. |
2024-04-16 |
2024-04-19 |
cat |
| Yingxin Lu, Ying Huang, Jiyu Jin, Jiahui Yu, Wei Lu, Shulei Zh. Design, synthesis, and biological evaluation of cathepsin B cleavage albumin-binding SN38 prodrug in breast cancer. Bioorganic chemistry. vol 147. 2024-04-15. PMID:38621338. |
histological immunohistochemical analyses further illuminate the multifaceted impact of our prodrug, showcasing elevated levels of apoptosis, downregulated expression of matrix metalloproteinases, and inhibition of angiogenesis, all critical factors contributing to the anti-metastatic effect observed. |
2024-04-15 |
2024-04-18 |
human |
| Hang Lv, Peiran Liu, Hai Hu, Xiaodong Li, Pengfei L. MiR-98-5p plays suppressive effects on IL-1β-induced chondrocyte injury associated with osteoarthritis by targeting CASP3. Journal of orthopaedic surgery and research. vol 19. issue 1. 2024-04-13. PMID:38615043. |
this study aims to explore how mir-98-5p affects osteoarthritis, focusing on its role in chondrocyte inflammation, apoptosis, and extracellular matrix (ecm) degradation. |
2024-04-13 |
2024-04-16 |
Not clear |
| Valentina Fustaino, Giuliana Papoff, Francesca Ruberti, Giovina Rubert. Co-Expression Network Analysis Unveiled lncRNA-mRNA Links Correlated to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Resistance and/or Intermediate Epithelial-to-Mesenchymal Transition Phenotypes in a Human Non-Small Cell Lung Cancer Cellular Model System. International journal of molecular sciences. vol 25. issue 7. 2024-04-13. PMID:38612674. |
processes enriched in the selected modules included rho (a, b, c) gtpase and regulatory signaling pathways, apoptosis, inflammatory and interleukin signaling pathways, cell adhesion, cell migration, cell and extracellular matrix organization, metabolism, and lipid metabolism. |
2024-04-13 |
2024-04-15 |
human |
| Haizhu Gao, Zhongxin Li, Lijun Gan, Xueying Che. The Role and Potential Mechanisms of Rehabilitation Exercise Improving Cardiac Remodeling. Journal of cardiovascular translational research. 2024-04-01. PMID:38558377. |
exercise training can mitigate cardiomyocyte apoptosis, reduce extracellular matrix deposition and fibrosis, promote angiogenesis, and regulate inflammatory response to improve cardiac remodeling. |
2024-04-01 |
2024-04-04 |
Not clear |
| Ieva Vanaga, Oksana Kolesova, Aleksandrs Kolesovs, Gunta Sture, Elvira Hagina, Jelena Storozenko, Liene Nikitina-Zake, Ludmila Viksn. Association of human leukocyte antigen class II alleles with epithelial cell apoptosis and extracellular matrix production in acute COVID-19. Central-European journal of immunology. vol 48. issue 4. 2024-04-01. PMID:38558559. |
association of human leukocyte antigen class ii alleles with epithelial cell apoptosis and extracellular matrix production in acute covid-19. |
2024-04-01 |
2024-04-04 |
human |