| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Antoku, Z Liu, D E Johnso. Inhibition of caspase proteases by CrmA enhances the resistance of human leukemic cells to multiple chemotherapeutic agents. Leukemia. vol 11. issue 10. 1997-10-23. PMID:9324287. |
proteases that are members of the caspase (or interleukin-1beta converting enzyme (ice)) protease family have been shown to be important mediators of apoptosis induced by fas activation, neurotrophic factor withdrawal, and detachment from extracellular matrix. |
1997-10-23 |
2023-08-12 |
human |
| C Yang, S W Li, H J Helminen, J S Khillan, Y Bao, D J Procko. Apoptosis of chondrocytes in transgenic mice lacking collagen II. Experimental cell research. vol 235. issue 2. 1997-10-16. PMID:9299161. |
in the present work, we used the same mice to show that chondrocytes undergo apoptosis in the absence of collagen ii, the major component of the extracellular matrix of cartilage. |
1997-10-16 |
2023-08-12 |
mouse |
| S Leuenroth, E Isaacson, C Lee, H Keeping, H H Simm. Integrin regulation of polymorphonuclear leukocyte apoxis during hypoxia is primarily dependent on very late activation antigens 3 and 5. Surgery. vol 122. issue 2. 1997-10-02. PMID:9288118. |
the regulation of polymorphonuclear leukocyte (pmn) apoptosis during hypoxia has not been previously characterized, and we hypothesized that integrin signaling by matrix proteins (laminin) would regulate pmn apoptosis. |
1997-10-02 |
2023-08-12 |
Not clear |
| N Zamzami, T Hirsch, B Dallaporta, P X Petit, G Kroeme. Mitochondrial implication in accidental and programmed cell death: apoptosis and necrosis. Journal of bioenergetics and biomembranes. vol 29. issue 2. 1997-09-25. PMID:9239543. |
at a second level, the consequences of mitochondrial dysfunction (collapse of the mitochondrial transmembrane potential, uncoupling of the respiratory chain, hyperproduction of superoxide anions, disruption of mitochondrial biogenesis, outflow of matrix calcium and glutathione, and release of soluble intermembrane proteins) can entail a biogenetic catastrophe culminating in the disruption of plasma membrane integrity (necrosis) and/or the activation and action of apoptogenic proteases with secondary endonuclease activation and consequent oligonucleosomal dna fragmentation (apoptosis). |
1997-09-25 |
2023-08-12 |
Not clear |
| G McGill, A Shimamura, R C Bates, R E Savage, D E Fishe. Loss of matrix adhesion triggers rapid transformation-selective apoptosis in fibroblasts. The Journal of cell biology. vol 138. issue 4. 1997-09-15. PMID:9265655. |
loss of matrix adhesion triggers rapid transformation-selective apoptosis in fibroblasts. |
1997-09-15 |
2023-08-12 |
Not clear |
| T Hattori, N Fujitsuka, A Kurogi, S Shind. [Protective effect of onpi-to (TJ-8117) on the expression of apoptosis in 5/6 nephrectomized rats]. Nihon Jinzo Gakkai shi. vol 39. issue 4. 1997-09-08. PMID:9198359. |
these results suggest that tj-8117 may inhibit apoptosis in the late stage of this model by suppressing matrix accumulation and progression of glomerulosclerosis. |
1997-09-08 |
2023-08-12 |
rat |
| M H Cardone, G S Salvesen, C Widmann, G Johnson, S M Frisc. The regulation of anoikis: MEKK-1 activation requires cleavage by caspases. Cell. vol 90. issue 2. 1997-08-28. PMID:9244305. |
certain cell types undergo apoptosis when they lose integrin-mediated contacts with the extracellular matrix ("anoikis"). |
1997-08-28 |
2023-08-12 |
Not clear |
| S Farrier, M Morga. bcl-2 expression in pilomatricoma. The American Journal of dermatopathology. vol 19. issue 3. 1997-08-25. PMID:9185911. |
the normal hair matrix undergoes defined cycles of growth (anagen), regression (catagen), and resting (telogen) that are regulated by programmed cell death (apoptosis). |
1997-08-25 |
2023-08-12 |
Not clear |
| R Gniadecki, M Hansen, H C Wul. Two pathways for induction of apoptosis by ultraviolet radiation in cultured human keratinocytes. The Journal of investigative dermatology. vol 109. issue 2. 1997-08-20. PMID:9242502. |
this phenomenon depended on differences in integrin-mediated adhesion, because blocking of integrin beta1 with a monoclonal antibody increased sensitivity of keratinocyte monolayers to uv and an increase in beta1 integrin receptor occupancy by plating on fibronectin, type iv collagen, or keratinocyte-derived extracellular matrix diminished the uv-dependent apoptosis. |
1997-08-20 |
2023-08-12 |
human |
| M Stanulla, J Wang, D S Chervinsky, S Thandla, P D Apla. DNA cleavage within the MLL breakpoint cluster region is a specific event which occurs as part of higher-order chromatin fragmentation during the initial stages of apoptosis. Molecular and cellular biology. vol 17. issue 7. 1997-07-24. PMID:9199342. |
we also show that site-specific cleavage within the mll bcr can be linked to the higher-order chromatin fragmentation that occurs during the initial stages of apoptosis, possibly through cleavage of dna loops at their anchorage sites to the nuclear matrix. |
1997-07-24 |
2023-08-12 |
Not clear |
| H I Roac. New aspects of endochondral ossification in the chick: chondrocyte apoptosis, bone formation by former chondrocytes, and acid phosphatase activity in the endochondral bone matrix. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 12. issue 5. 1997-07-16. PMID:9144346. |
new aspects of endochondral ossification in the chick: chondrocyte apoptosis, bone formation by former chondrocytes, and acid phosphatase activity in the endochondral bone matrix. |
1997-07-16 |
2023-08-12 |
chicken |
| R E Vilar, D Ghael, M Li, D D Bhagat, L M Arrigo, M K Cowman, H S Dweck, L Rosenfel. Nitric oxide degradation of heparin and heparan sulphate. The Biochemical journal. vol 324 ( Pt 2). 1997-07-08. PMID:9182706. |
these observations may be relevant to various pathophysiological processes in which extracellular matrix is degraded, such as bone development, apoptosis, tissue damage from inflammatory responses and possible release of growth factors and cytokines. |
1997-07-08 |
2023-08-12 |
Not clear |
| T Sugimori, D L Griffith, M A Arnaou. Emerging paradigms of integrin ligand binding and activation. Kidney international. vol 51. issue 5. 1997-07-03. PMID:9150458. |
adhesion of cells to each other or to the extracellular matrix provides essential signals that regulate many cellular functions including cell migration, proliferation, differentiation and apoptosis. |
1997-07-03 |
2023-08-12 |
Not clear |
| C Gueth-Hallonet, K Weber, M Osbor. Cleavage of the nuclear matrix protein NuMA during apoptosis. Experimental cell research. vol 233. issue 1. 1997-06-30. PMID:9184071. |
cleavage of the nuclear matrix protein numa during apoptosis. |
1997-06-30 |
2023-08-12 |
Not clear |
| H Hai, M H Hardy, W D Black, M T Goldber. The in vivo effect of the tumor promoter 12-O-tetradecanoylphorbol-13-acetate on N-methyl-N-nitrosourea-induced apoptosis in mouse hair follicles. Fundamental and applied toxicology : official journal of the Society of Toxicology. vol 35. issue 2. 1997-05-28. PMID:9038238. |
this study assessed the in vivo relationship between apoptosis induced by the tumor initiator n-methyl-n-nitrosourea (mnu) and action of the tumor promoter 12-o-tetradecanoylphorbol-13-acetate (tpa) in mouse hair follicle matrix cells. |
1997-05-28 |
2023-08-12 |
mouse |
| N Fratzl-Zelman, H Hörandner, E Luegmayr, F Varga, A Ellinger, M P Erlee, K Klaushofe. Effects of triiodothyronine on the morphology of cells and matrix, the localization of alkaline phosphatase, and the frequency of apoptosis in long-term cultures of MC3T3-E1 cells. Bone. vol 20. issue 3. 1997-05-28. PMID:9071473. |
effects of triiodothyronine on the morphology of cells and matrix, the localization of alkaline phosphatase, and the frequency of apoptosis in long-term cultures of mc3t3-e1 cells. |
1997-05-28 |
2023-08-12 |
Not clear |
| N Fratzl-Zelman, H Hörandner, E Luegmayr, F Varga, A Ellinger, M P Erlee, K Klaushofe. Effects of triiodothyronine on the morphology of cells and matrix, the localization of alkaline phosphatase, and the frequency of apoptosis in long-term cultures of MC3T3-E1 cells. Bone. vol 20. issue 3. 1997-05-28. PMID:9071473. |
the effects of triiodothyronine (t3) on the localization and morphology of alkaline phosphatase (alp)-positive cells, matrix formation, and apoptosis in mc3t3-e1 cells cultured up to 6 weeks were investigated by light and electron microscopy. |
1997-05-28 |
2023-08-12 |
Not clear |
| H A Chapman, R J Riese, G P Sh. Emerging roles for cysteine proteases in human biology. Annual review of physiology. vol 59. 1997-05-27. PMID:9074757. |
these roles appear to include apoptosis, mhc class ii immune responses, prohormone processing, and extracellular matrix remodeling important to bone development. |
1997-05-27 |
2023-08-12 |
human |
| N Guo, H C Krutzsch, J K Inman, D D Robert. Thrombospondin 1 and type I repeat peptides of thrombospondin 1 specifically induce apoptosis of endothelial cells. Cancer research. vol 57. issue 9. 1997-05-21. PMID:9135017. |
these results demonstrate that induction of apoptosis by the tsp1 analogues is not a general cytotoxic effect and is conditional on a lack of strong survival-promoting signals, such as those provided by a fibronectin matrix. |
1997-05-21 |
2023-08-12 |
cattle |
| N Guo, H C Krutzsch, J K Inman, D D Robert. Thrombospondin 1 and type I repeat peptides of thrombospondin 1 specifically induce apoptosis of endothelial cells. Cancer research. vol 57. issue 9. 1997-05-21. PMID:9135017. |
the antitumor activity of tsp1 may therefore result from an increased sensitivity to apoptosis in endothelial cells adjacent to a provisional matrix during formation of vascular beds in tumors expressing tsp1. |
1997-05-21 |
2023-08-12 |
cattle |