| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H H Berendsen, C L Broekkam. Antagonism of the 5-HT1A receptor stimulus in a conditioned taste aversion procedure. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 9. issue 4. 1999-09-03. PMID:10422896. |
antagonism of the 5-ht1a receptor stimulus in a conditioned taste aversion procedure. |
1999-09-03 |
2023-08-12 |
mouse |
| H H Berendsen, C L Broekkam. Antagonism of the 5-HT1A receptor stimulus in a conditioned taste aversion procedure. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 9. issue 4. 1999-09-03. PMID:10422896. |
the conditioned taste aversion procedure in mice was used to test for blockade of the drug stimulus of the 5-ht1a receptor agonists (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin hbr (8-oh-dpat), 1-(4-trifluoromethyl-2-pyridinyl)-4- [4-[2-oxo-1-pyrrolidinyl]butyl]piperazine (e)-2-butenedioate (org 13011) and the 5-ht reuptake inhibitor fluoxetine. |
1999-09-03 |
2023-08-12 |
mouse |
| H H Berendsen, C L Broekkam. Antagonism of the 5-HT1A receptor stimulus in a conditioned taste aversion procedure. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 9. issue 4. 1999-09-03. PMID:10422896. |
the conditioned taste aversion induced by 8-oh-dpat (0.22 mg/kg) and org 13011 (0.5 mg/kg) was readily blocked by the 5-ht1a receptor antagonist n-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-n-(2-pyridinyl) cyclohexanecarboxamide trihydrochloride (way-100635) (0.1 mg/kg). |
1999-09-03 |
2023-08-12 |
mouse |
| H H Berendsen, C L Broekkam. Antagonism of the 5-HT1A receptor stimulus in a conditioned taste aversion procedure. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 9. issue 4. 1999-09-03. PMID:10422896. |
it is concluded that the conditioned taste aversion induced by 8-oh-dpat or org 13011 is mediated via 5-ht1a receptors. |
1999-09-03 |
2023-08-12 |
mouse |
| H H Berendsen, C L Broekkam. Antagonism of the 5-HT1A receptor stimulus in a conditioned taste aversion procedure. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 9. issue 4. 1999-09-03. PMID:10422896. |
the results suggest that the conditioned taste aversion induced by fluoxetine is not exclusively mediated by 5-ht1a receptors nor exclusively by 5-ht2 receptors. |
1999-09-03 |
2023-08-12 |
mouse |
| F Jenck, J R Martin, J L Morea. The 5-HT1A receptor agonist flesinoxan increases aversion in a model of panic-like anxiety in rats. Journal of psychopharmacology (Oxford, England). vol 13. issue 2. 1999-08-27. PMID:10475723. |
the 5-ht1a receptor agonist flesinoxan increases aversion in a model of panic-like anxiety in rats. |
1999-08-27 |
2023-08-12 |
rat |
| F Jenck, J R Martin, J L Morea. The 5-HT1A receptor agonist flesinoxan increases aversion in a model of panic-like anxiety in rats. Journal of psychopharmacology (Oxford, England). vol 13. issue 2. 1999-08-27. PMID:10475723. |
data suggest that selective activation of 5-ht1a receptors (pre- and/or post-synaptic in brain and/or periphery) following systemic administration of 5-ht1a receptor full agonists exacerbates aversion in animals or patients with panic anxiety; activation of these receptor subtypes may probably mediate the panicogenic action reported under certain circumstances with non-selective 5-ht mimetics. |
1999-08-27 |
2023-08-12 |
rat |
| K C Lian. Pre- or post-training injection of buspirone impaired retention in the inhibitory avoidance task: involvement of amygdala 5-HT1A receptors. The European journal of neuroscience. vol 11. issue 5. 1999-05-26. PMID:10215901. |
pre- or post-training injection of buspirone impaired retention in the inhibitory avoidance task: involvement of amygdala 5-ht1a receptors. |
1999-05-26 |
2023-08-12 |
rat |
| K C Lian. Pre- or post-training injection of buspirone impaired retention in the inhibitory avoidance task: involvement of amygdala 5-HT1A receptors. The European journal of neuroscience. vol 11. issue 5. 1999-05-26. PMID:10215901. |
these findings suggest that buspirone may modulate memory storage processes in the inhibitory avoidance task through an action on amygdaloid 5-ht1a receptors. |
1999-05-26 |
2023-08-12 |
rat |
| F G Graeff, C F Netto, H Zangross. The elevated T-maze as an experimental model of anxiety. Neuroscience and biobehavioral reviews. vol 23. issue 2. 1999-03-29. PMID:9884116. |
the anxiolytic agents diazepam (benzodiazepine), buspirone and ipsapirone (5-ht1a agonists) as well as ritanserin (5-ht2 antagonist) selectively impaired inhibitory avoidance while leaving one-way escape unchanged. |
1999-03-29 |
2023-08-12 |
rat |
| S O Ogren, I Misan. Animal models for studying serotonin (5-HT) receptor subtypes: relationship to 5-HT system pathologies. Nuclear medicine and biology. vol 25. issue 8. 1999-03-23. PMID:9863561. |
the present study focused on the particular role of 5-ht1a receptor subtype in aversive learning, i.e., the passive avoidance (pa) task in the rat. |
1999-03-23 |
2023-08-12 |
rat |
| A Menese. Physiological, pathophysiological and therapeutic roles of 5-HT systems in learning and memory. Reviews in the neurosciences. vol 9. issue 4. 1999-03-23. PMID:9886142. |
for instance, when pre- vs post-training administration of 5-ht1a agonist, 5-ht2 antagonists and 5-ht4 agonists have been compared contrasting findings were reported in aversive and appetitive learning tasks. |
1999-03-23 |
2023-08-12 |
Not clear |
| I Misane, C Johansson, S O Ogre. Analysis of the 5-HT1A receptor involvement in passive avoidance in the rat. British journal of pharmacology. vol 125. issue 3. 1999-03-04. PMID:9806333. |
analysis of the 5-ht1a receptor involvement in passive avoidance in the rat. |
1999-03-04 |
2023-08-12 |
rat |
| I Misane, C Johansson, S O Ogre. Analysis of the 5-HT1A receptor involvement in passive avoidance in the rat. British journal of pharmacology. vol 125. issue 3. 1999-03-04. PMID:9806333. |
the effects of the 5-ht2a/2c agonist dob, the selective 5-ht1a agonist ndo 008 (3-dipropylamino-5-hydroxychroman), and the two enantiomers of the selective 5-ht1a agonist 8-oh-dpat (r(+)-8-oh-dpat and s(-)-8-oh-dpat) were studied in a step-through passive avoidance (pa) test in the male rat. |
1999-03-04 |
2023-08-12 |
rat |
| I Misane, C Johansson, S O Ogre. Analysis of the 5-HT1A receptor involvement in passive avoidance in the rat. British journal of pharmacology. vol 125. issue 3. 1999-03-04. PMID:9806333. |
.7 these findings indicate that the deficit of passive avoidance retention induced by the 5-ht1a agonists is mainly a result of stimulation of postsynaptic 5-ht1a receptors but not 5-ht2a receptors. |
1999-03-04 |
2023-08-12 |
rat |
| S Ramboz, R Oosting, D A Amara, H F Kung, P Blier, M Mendelsohn, J J Mann, D Brunner, R He. Serotonin receptor 1A knockout: an animal model of anxiety-related disorder. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 24. 1998-12-28. PMID:9826725. |
in the present report, we demonstrate that mice without 5-ht1a receptors display decreased exploratory activity and increased fear of aversive environments (open or elevated spaces). |
1998-12-28 |
2023-08-12 |
mouse |
| I Misane, H Razani, F H Wang, A Jansson, K Fuxe, S O Ogre. Intraventricular galanin modulates a 5-HT1A receptor-mediated behavioural response in the rat. The European journal of neuroscience. vol 10. issue 4. 1998-10-22. PMID:9749777. |
to modify the impairment of passive avoidance retention induced by the selective 5-ht1a agonist 8-hydroxy-2-(di-n-propyloamino)tetralin (8-oh-dpat) when injected prior to training. |
1998-10-22 |
2023-08-12 |
rat |
| I Misane, H Razani, F H Wang, A Jansson, K Fuxe, S O Ogre. Intraventricular galanin modulates a 5-HT1A receptor-mediated behavioural response in the rat. The European journal of neuroscience. vol 10. issue 4. 1998-10-22. PMID:9749777. |
furthermore, both the impairment of passive avoidance and the 5-ht syndrome were completely blocked by the 5-ht1a receptor antagonist way 100635 (0.1 mg/kg). |
1998-10-22 |
2023-08-12 |
rat |
| I Misane, H Razani, F H Wang, A Jansson, K Fuxe, S O Ogre. Intraventricular galanin modulates a 5-HT1A receptor-mediated behavioural response in the rat. The European journal of neuroscience. vol 10. issue 4. 1998-10-22. PMID:9749777. |
8-oh-dpat given at a low dose 0.03 mg/kg, which presumably stimulates somatodendritic 5-ht1a autoreceptors in vivo, did not alter passive avoidance retention or induce any visually detectable signs of the 5-ht syndrome. |
1998-10-22 |
2023-08-12 |
rat |
| M T Hsieh, C R Wu, C C Hsie. Ameliorating effect of p-hydroxybenzyl alcohol on cycloheximide-induced impairment of passive avoidance response in rats: interactions with compounds acting at 5-HT1A and 5-HT2 receptors. Pharmacology, biochemistry, and behavior. vol 60. issue 2. 1998-08-17. PMID:9632215. |
ameliorating effect of p-hydroxybenzyl alcohol on cycloheximide-induced impairment of passive avoidance response in rats: interactions with compounds acting at 5-ht1a and 5-ht2 receptors. |
1998-08-17 |
2023-08-12 |
rat |