| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lancheng Wei, Hongjian He, Shuting Yang, Qianqian Shi, Xinhang Wang, Liyuan Huang, Jianyong Lu, Yinghui Shen, Kaikai Zhi, Junni Xiang, Chengying Chen, Jiao Mo, Zhijian Zheng, Yunfeng Zou, Xiaobo Yang, Shen Tang, Xiyi Li, Cailing L. Synergistic suppression of BDNF via epigenetic mechanism deteriorating learning and memory impairment caused by Mn and Pb co-exposure. Ecotoxicology and environmental safety. vol 277. 2024-04-24. PMID:38657452. |
synergistic suppression of bdnf via epigenetic mechanism deteriorating learning and memory impairment caused by mn and pb co-exposure. |
2024-04-24 |
2024-04-28 |
mouse |
| Lancheng Wei, Hongjian He, Shuting Yang, Qianqian Shi, Xinhang Wang, Liyuan Huang, Jianyong Lu, Yinghui Shen, Kaikai Zhi, Junni Xiang, Chengying Chen, Jiao Mo, Zhijian Zheng, Yunfeng Zou, Xiaobo Yang, Shen Tang, Xiyi Li, Cailing L. Synergistic suppression of BDNF via epigenetic mechanism deteriorating learning and memory impairment caused by Mn and Pb co-exposure. Ecotoxicology and environmental safety. vol 277. 2024-04-24. PMID:38657452. |
suppression of bdnf is implicated in learning and memory impairment induced by exposure to manganese (mn) or lead (pb) individually. |
2024-04-24 |
2024-04-28 |
mouse |
| Lancheng Wei, Hongjian He, Shuting Yang, Qianqian Shi, Xinhang Wang, Liyuan Huang, Jianyong Lu, Yinghui Shen, Kaikai Zhi, Junni Xiang, Chengying Chen, Jiao Mo, Zhijian Zheng, Yunfeng Zou, Xiaobo Yang, Shen Tang, Xiyi Li, Cailing L. Synergistic suppression of BDNF via epigenetic mechanism deteriorating learning and memory impairment caused by Mn and Pb co-exposure. Ecotoxicology and environmental safety. vol 277. 2024-04-24. PMID:38657452. |
our findings reveal that co-exposure to mn and pb leads to severe learning and memory impairment in mice, which correlates with the accumulation of metals in the hippocampus and synergistic suppression of bdnf. |
2024-04-24 |
2024-04-28 |
mouse |
| Lancheng Wei, Hongjian He, Shuting Yang, Qianqian Shi, Xinhang Wang, Liyuan Huang, Jianyong Lu, Yinghui Shen, Kaikai Zhi, Junni Xiang, Chengying Chen, Jiao Mo, Zhijian Zheng, Yunfeng Zou, Xiaobo Yang, Shen Tang, Xiyi Li, Cailing L. Synergistic suppression of BDNF via epigenetic mechanism deteriorating learning and memory impairment caused by Mn and Pb co-exposure. Ecotoxicology and environmental safety. vol 277. 2024-04-24. PMID:38657452. |
in summary, our experiments demonstrate that simultaneous exposure to mn and pb results in more severe hippocampus-dependent learning and memory impairment, which is attributed to epigenetic suppression of bdnf mediated by pp2a regulation. |
2024-04-24 |
2024-04-28 |
mouse |
| Yunlin Feng, Jia Qin, Yanfei Lu, Mengdie Wang, Shengqiang Wang, Foquan Lu. Suberoylanilide hydroxamic acid attenuates cognitive impairment in offspring caused by maternal surgery during mid-pregnancy. PloS one. vol 19. issue 3. 2024-03-29. PMID:38551911. |
our results showed that maternal propofol exposure during middle pregnancy impaired the water-maze learning and memory of the offspring rats, increased the protein level of hdac2 and reduced the protein levels of p-creb, bdnf and p-trkb in the hippocampus of the offspring, and such effects were exacerbated by surgery. |
2024-03-29 |
2024-04-01 |
rat |
| Matthias Wilhelm Voigt, Jens Schepers, Jacqueline Haas, Oliver von Bohlen Und Halbac. Reduced Levels of Brain-Derived Neurotrophic Factor Affect Body Weight, Brain Weight and Behavior. Biology. vol 13. issue 3. 2024-03-27. PMID:38534429. |
bdnf plays a role in the regulation of body weight and neuronal plasticity and is, therefore, also involved in processes associated with learning and memory formation. |
2024-03-27 |
2024-03-29 |
mouse |
| Raj Katariya, Kartikey Mishra, Shivkumar Sammeta, Milind Umekar, Nandkishor Kotagale, Brijesh Taksand. Agmatine mitigates behavioral abnormalities and neurochemical dysregulation associated with 3-Nitropropionic acid-induced Huntington's disease in rats. Neurotoxicology. 2024-03-07. PMID:38453033. |
agmatine treatment not only improved the 3-np-induced motor incoordination, depression-like behavior, rota-rod performance, and learning and memory impairment but also normalized the gaba/glutamate, bdnf, il-6, and tnf-α levels in discrete brain areas. |
2024-03-07 |
2024-03-10 |
rat |
| Victor Hugo de Oliveira Segundo, Kesley Pablo Morais de Azevedo, Gidyenne Christine Bandeira Silva de Medeiros, Ádala Nayana de Sousa Mata, Grasiela Piuveza. Association between sedentary behavior and Brain-Derived Neurotrophic Factor (BDNF) in children and adolescents: A protocol for systematic review and meta-analysis. PloS one. vol 19. issue 3. 2024-03-05. PMID:38442097. |
there is evidence in the literature suggesting that high time spent in sedentary behavior (sb) can reduce the brain-derived neurotrophic factor (bdnf) levels, an important neurotrophin that plays a role in modulating cognition, learning and memory. |
2024-03-05 |
2024-03-08 |
Not clear |
| Masataka Kiuchi, Tadashi Uno, Tatsuya Hasegawa, Katsuhiro Koyama, Masahiro Horiuch. Influence of short-term hypoxic exposure on spatial learning and memory function and brain-derived neurotrophic factor in rats-A practical implication to human's lost way. Frontiers in behavioral neuroscience. vol 18. 2024-02-21. PMID:38380151. |
the present study aimed to investigate the effects of a short period of normobaric hypoxic exposure on spatial learning and memory, and brain-derived neurotrophic factor (bdnf) levels in the rat hippocampus. |
2024-02-21 |
2024-02-23 |
human |
| Svitlana V Bach, Allison J Bauman, Darya Hosein, Jennifer J Tuscher, Lara Ianov, Kelsey M Greathouse, Benjamin W Henderson, Jeremy H Herskowitz, Keri Martinowich, Jeremy J Da. Distinct roles of Bdnf I and Bdnf IV transcript variant expression in hippocampal neurons. Hippocampus. 2024-02-16. PMID:38362938. |
brain-derived neurotrophic factor (bdnf) plays a critical role in brain development, dendritic growth, synaptic plasticity, as well as learning and memory. |
2024-02-16 |
2024-02-18 |
rat |
| Mengdie Wang, Namin Feng, Jia Qin, Shengqiang Wang, Jiabao Chen, Shaojie Qian, Yulin Liu, Foquan Lu. Abdominal Surgery under Ketamine Anesthesia during Second Trimester Impairs Hippocampal Learning and Memory of Offspring by Regulating Dendrite Spine Remodeling in Rats. Neurotoxicology. 2024-02-12. PMID:38346645. |
senegenin alleviated the learning and memory impairment, and increased the protein levels of nedd9, bdnf, p-trkb, syn and psd-95 and the density of dendritic spines in the offspring of the surgery group. |
2024-02-12 |
2024-02-15 |
rat |
| Naomi Lomeli, Diana C Pearre, Maureen Cruz, Kaijun Di, Joni L Ricks-Oddie, Daniela A Bot. Cisplatin induces BDNF downregulation in middle-aged female rat model while BDNF enhancement attenuates cisplatin neurotoxicity. Experimental neurology. 2024-02-09. PMID:38336286. |
brain-derived neurotrophic factor (bdnf) plays an essential role in neurogenesis, learning and memory. |
2024-02-09 |
2024-02-12 |
rat |
| Clémence Leger, Aurore Quirié, Alexandre Méloux, Estelle Fontanier, Rémi Chaney, Christelle Basset, Stéphanie Lemaire, Philippe Garnier, Anne Prigent-Tessie. Impact of Exercise Intensity on Cerebral BDNF Levels: Role of FNDC5/Irisin. International journal of molecular sciences. vol 25. issue 2. 2024-01-27. PMID:38279218. |
the positive effects of physical exercise (ex) are well known to be mediated by cerebral bdnf (brain-derived neurotrophic factor), a neurotrophin involved in learning and memory, the expression of which could be induced by circulating irisin, a peptide derived from fibronectin type iii domain-containing protein 5 (fndc5) produced by skeletal muscle contraction. |
2024-01-27 |
2024-01-29 |
rat |
| Hideo Takekoshi, Masaki Fujishima, Taiki Miyazawa, Ohki Higuchi, Takahiko Fujikawa, Teruo Miyazaw. Simultaneous Intake of Chlorella and Ascidian Ethanolamine Plasmalogen Accelerates Activation of BDNF-TrkB-CREB Signaling in Rats. Molecules (Basel, Switzerland). vol 29. issue 2. 2024-01-23. PMID:38257270. |
bdnf is a neurotrophin that binds to tropomyosin receptor kinase b (trkb), a specific receptor on target cell surfaces; it acts on neuronal formation, development, growth, and repair via transcription factors, such as camp response element-binding protein (creb), and it is involved in learning and memory. |
2024-01-23 |
2024-01-25 |
human |
| Behnaz Valipour, Sara Simorgh, Marjan Mirsalehi, Salah Moradi, Farzad Taghizadeh-Hesary, Elham Seidkhani, Zeinab Akbarnejad, Rafieh Alizade. Improvement of spatial learning and memory deficits by intranasal administration of human olfactory ecto-mesenchymal stem cells in an Alzheimer's disease rat model. Brain research. 2024-01-19. PMID:38242524. |
based on the results, intranasal administration of oe-mscs significantly reduced aβ accumulation and neuronal loss, improved learning and memory impairments, and increased levels of bdnf (brain-derived neurotrophic factor) and nmdar (n-methyl-d-aspartate receptors) in the ad rat model. |
2024-01-19 |
2024-01-22 |
human |
| Mohammad Fallahi, Ali Akbar Masoudi, Rasoul Vaez Torshiz. Genetic variants in the TAC1 transcriptional regulatory region affect on trainability and excitability levels in Belgian Malinois dogs. Veterinary medicine and science. vol 10. issue 1. 2024-01-16. PMID:38227710. |
our previous results suggested that the bdnf, cck and tac1 genes are associated with learning and memory in canines. |
2024-01-16 |
2024-01-19 |
Not clear |
| Sama Jaberi, Margaret Fahnestoc. Mechanisms of the Beneficial Effects of Exercise on Brain-Derived Neurotrophic Factor Expression in Alzheimer's Disease. Biomolecules. vol 13. issue 11. 2023-11-25. PMID:38002258. |
here, we review recent literature on the mechanisms behind exercise-induced bdnf upregulation and its effects on improving learning and memory and on alzheimer's disease pathology. |
2023-11-25 |
2023-11-28 |
Not clear |
| Jie Yuan, Jing Gao, Kai-Qi Su, Xiao-Dong Fen. [Electroacupuncture improves learning and memory impairment and enhances hippocampal synaptic plasticity through BDNF/TRKB/CREB signaling pathway in cerebral ischemia-reperfusion injury rats]. Zhen ci yan jiu = Acupuncture research. vol 48. issue 9. 2023-09-20. PMID:37730254. |
to observe the effect of electroacupuncture on brain-derived neurotrophin factor (bdnf) / tyrosine kinase receptor b (trkb) / cyclic adenosine monophosphate response element binding protein (creb) pathway, synaptic plasticity marker protein and synaptic ultrastructure in the hippocampus of rats with learning and memory impairment induced by cerebral ischemia reperfusion (ir), so as to explore its mechanisms underlying improvement of cognitive impairment after stroke. |
2023-09-20 |
2023-10-07 |
rat |
| Eleni H Moschonas, Tyler S Ranellone, Vincent J Vozzella, Piper L Rennerfeldt, Corina O Bondi, Ellen M Annas, Rachel A Bittner, Dana M Tamura, Rithika I Reddy, Rithik R Eleti, Jeffrey P Cheng, Jessica M Jarvis, Ericka L Fink, Anthony E Klin. Efficacy of a music-based intervention in a preclinical model of traumatic brain injury: An initial foray into a novel and non-pharmacological rehabilitative therapy. Experimental neurology. 2023-09-19. PMID:37726048. |
motor (beam-walk), cognitive (acquisition of spatial learning and memory), anxiety-like behavior (open field), coping (shock probe defensive burying), as well as histopathology (lesion volume), neuroplasticity (bdnf), and neuroinflammation (iba1, and cd163) were assessed. |
2023-09-19 |
2023-10-07 |
rat |
| S Mohammad Ahmadi-Soleimani, Ghulam Yahya Amiry, Elnaz Khordad, Maha Masoudi, Farimah Behesht. Omega-3 fatty acids prevent nicotine withdrawal-induced impairment of learning and memory via affecting oxidative status, inflammatory response, cholinergic activity, BDNF and amyloid-B in rat hippocampal tissues. Life sciences. 2023-09-18. PMID:37722588. |
omega-3 fatty acids prevent nicotine withdrawal-induced impairment of learning and memory via affecting oxidative status, inflammatory response, cholinergic activity, bdnf and amyloid-b in rat hippocampal tissues. |
2023-09-18 |
2023-10-07 |
rat |