| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jing-Yu Qi, Liu-Kun Yang, Xin-Shang Wang, Min Wang, Xu-Bo Li, Ban Feng, Yu-Mei Wu, Shui-Bing Liu, Kun Zhan. Mechanism of CNS regulation by irisin, a multifunctional protein. Brain research bulletin. 2022-07-19. PMID:35850187. |
it has been reported that irisin can cross the blood-brain barrier and increase the expression of a brain-derived neurotrophic factor (bdnf) in the hippocampus, which improves learning and memory. |
2022-07-19 |
2023-08-14 |
Not clear |
| Laura Boi, Sabrina Petralla, Barbara Monti, Giuseppe Talani, Enrico Sanna, Maria Giuseppina Pisu, Giulia Calderisi, Elisabetta Maciocco, Mariangela Serra, Alessandra Concas, Patrizia Porc. Chronic treatment with hormonal contraceptives alters hippocampal BDNF and histone H3 post-translational modifications but not learning and memory in female rats. Hormones and behavior. vol 144. 2022-07-05. PMID:35785712. |
chronic treatment with hormonal contraceptives alters hippocampal bdnf and histone h3 post-translational modifications but not learning and memory in female rats. |
2022-07-05 |
2023-08-14 |
rat |
| Khairunnuur Fairuz Azman, Rahimah Zakari. Recent Advances on the Role of Brain-Derived Neurotrophic Factor (BDNF) in Neurodegenerative Diseases. International journal of molecular sciences. vol 23. issue 12. 2022-06-24. PMID:35743271. |
the signaling cascades initiated by bdnf and its receptor are the key regulators of synaptic plasticity, which plays important role in learning and memory formation. |
2022-06-24 |
2023-08-14 |
Not clear |
| Tae-Woon Kim, Sang-Seo Park, Hye-Sang Par. Effects of Exercise Training during Advanced Maternal Age on the Cognitive Function of Offspring. International journal of molecular sciences. vol 23. issue 10. 2022-05-28. PMID:35628329. |
we found that the offspring of mothers with ama without exercise training had decreased spatial learning and memory, brain-derived neurotrophic factor (bdnf) and postsynaptic density protein 95 (psd-95) protein levels, neurogenesis, and mitochondrial function, as well as hippocampal cell death. |
2022-05-28 |
2023-08-13 |
Not clear |
| Eun-Jung Yoon, Yunseo Choi, Dongsun Par. Improvement of Cognitive Function in Ovariectomized Rats by Human Neural Stem Cells Overexpressing Choline Acetyltransferase via Secretion of NGF and BDNF. International journal of molecular sciences. vol 23. issue 10. 2022-05-28. PMID:35628371. |
we evaluated whether an increase in brain-derived neurotrophic factor (bdnf) and nerve-growth factor (ngf) levels, through transplantation of choline acetyltransferase (chat)-overexpressing neural stem cells (f3.chat), improved learning and memory in ovariectomized rats. |
2022-05-28 |
2023-08-13 |
mouse |
| Darren Ty, Barbara Kania, Alexis Sotelo, Jonathan Wisc. Gut Dysbiosis: A Review of the Effects of a High-Fat Diet on Iron Regulation and Brain-Derived Neurotrophic Factor (BDNF) Expression in the Brain-Gut Axis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35556900. |
one particular protein of interest is called brain-derived neurotrophic factor (bdnf), which is a protein found in the brain that is important for learning and memory through stabilization of long-term potentiation (ltp). |
2022-05-13 |
2023-08-13 |
human |
| Johanna L Keeler, Olivia Patsalos, Raymond Chung, Ulrike Schmidt, Gerome Breen, Janet Treasure, Himmerich Hubertus, Bethan Dalto. Short communication: Serum levels of brain-derived neurotrophic factor and association with pro-inflammatory cytokines in acute and recovered anorexia nervosa. Journal of psychiatric research. vol 150. 2022-03-29. PMID:35349796. |
brain-derived neurotrophic factor (bdnf) is a neuroprotective molecule known to be involved in neuroplasticity, learning and memory. |
2022-03-29 |
2023-08-13 |
Not clear |
| Dai-Ting Lin, Ning-Juo Kao, Tzu-Wen Liu Cross, Wei-Ju Lee, Shyh-Hsiang Li. Effects of ketogenic diet on cognitive functions of mice fed high-fat-high-cholesterol diet. The Journal of nutritional biochemistry. vol 104. 2022-03-28. PMID:35196576. |
after consuming the hfhc diet for 16 weeks and subsequently receiving the mct diet for 8 weeks, results showed that the mice fed a mct diet had significantly better spatial learning and memory performance, lower expression of nuclear factor kappa-light-chain-enhancer of activated b cells (nf-κb), tumor necrosis factor-α (tnf-α), glial fibrillary acidic protein (gfap), amyloid protein precursor (app) and phosphate tau, and higher expression of brain-derived neurotrophic factor (bdnf) than the mice fed the hfhc diet. |
2022-03-28 |
2023-08-16 |
mouse |
| Divya Yadav, Pravir Kuma. Restoration and targeting of aberrant neurotransmitters in Parkinson's disease therapeutics. Neurochemistry international. 2022-03-25. PMID:35331828. |
while the non-dopaminergic system can efficiently target non-motor symptoms, for instance, the noradrenergic system regulates the synthesis of bdnf via the mapk pathway, which is important in learning and memory. |
2022-03-25 |
2023-08-13 |
Not clear |
| Joyce Keife. Regulation of AMPAR trafficking in synaptic plasticity by BDNF and the impact of neurodegenerative disease. Journal of neuroscience research. 2022-02-07. PMID:35128708. |
bdnf is a neurotrophic factor that supports neuronal growth and is required for learning and memory. |
2022-02-07 |
2023-08-13 |
Not clear |
| Medha Kaushik, Pooja Kaushik, Suhel Parve. Memory Related Molecular Signatures: The Pivots for Memory Consolidation and Alzheimer's Related Memory Decline. Ageing research reviews. 2022-02-01. PMID:35104629. |
research on learning and memory has identified several molecular signatures such as protein kinase m zeta (pkmζ), calcium/calmodulin-dependent protein kinase ii (camkii), brain-derived neurotrophic factor (bdnf), camp-response element binding protein (creb), activity-regulated cytoskeleton-associated protein (arc) crucial for the maintenance and stabilization of long-term memory in the brain. |
2022-02-01 |
2023-08-13 |
Not clear |
| Mariana Angoa-Pérez, John H Anneken, Donald M Kuh. The Role of Brain-Derived Neurotrophic Factor in the Pathophysiology of Psychiatric and Neurological Disorders. Journal of psychiatry and psychiatric disorders. vol 1. issue 5. 2022-01-31. PMID:35098038. |
bdnf is highly expressed in limbic structures and cerebral cortex, making it a crucial factor in the regulation of learning and memory, affective behaviors and reward processes. |
2022-01-31 |
2023-08-13 |
human |
| Serena Camuso, Piergiorgio La Rosa, Maria Teresa Fiorenza, Sonia Canterin. Pleiotropic effects of BDNF on the cerebellum and hippocampus: Implications for neurodevelopmental disorders. Neurobiology of disease. 2022-01-02. PMID:34974125. |
after birth, bdnf acts in the cerebellum as a mitogenic and chemotactic factor, stimulating the cerebellar granule cell precursors to proliferate, migrate and maturate, while in the hippocampus bdnf plays a fundamental role in synaptic transmission and plasticity, representing a key regulator for the long-term potentiation, learning and memory. |
2022-01-02 |
2023-08-13 |
Not clear |
| Debora Cutuli, Eugenia Landolfo, Laura Petrosini, Francesca Gelf. Environmental Enrichment Effects on the Brain-Derived Neurotrophic Factor Expression in Healthy Condition, Alzheimer's Disease, and Other Neurodegenerative Disorders. Journal of Alzheimer's disease : JAD. 2021-12-13. PMID:34897089. |
brain-derived neurotrophic factor (bdnf), a protein belonging to the neurotrophin family, is known to be heavily involved in synaptic plasticity processes that support brain development, post-lesion regeneration, and cognitive performances, such as learning and memory. |
2021-12-13 |
2023-08-13 |
Not clear |
| Mohadeseh Chahkandi, Gholamreza Sepehri, Gholamreza Komeili, Mohammad Khaksari Hadad, Elham Haghparast, Majid Chahkand. The different role of G-protein-coupled receptor 30 (GPR30) in the interaction effects of marijuana and estradiol on spatial learning and memory at different ages. Brain research bulletin. vol 178. 2021-12-09. PMID:34800583. |
furthermore, this study showed that hippocampal bdnf does not have any role in the interaction effects of m and e2 on spatial learning and memory in young and old rats. |
2021-12-09 |
2023-08-13 |
rat |
| Weifeng Shan, Yini Wu, Xin Han, Qin Chen, Jimin W. The mechanism of sevoflurane post-treatment alleviating hypoxic-ischemic encephalopathy by affecting histone methyltransferase G9a in rats. Bioengineered. vol 12. issue 2. 2021-12-08. PMID:34672892. |
the learning and memory ability and the levels of nerve growth factor (ngf)/brain-derived neurotrophic factor (bdnf) were evaluated and determined. |
2021-12-08 |
2023-08-13 |
rat |
| Cigdem Cicek, Emine Eren-Koçak, Pelin Telkoparan-Akillilar, Muslum Gok, Ebru Bodu. cAMP/PKA-CREB-BDNF signaling pathway in hippocampus of rats subjected to chemically-induced phenylketonuria. Metabolic brain disease. 2021-11-20. PMID:34800207. |
in relation to learning and memory, the hippocampal pka / creb / bdnf pathway may play a role in learning deficits in pku patients. |
2021-11-20 |
2023-08-13 |
rat |
| Bo-Wen Chen, Kai-Wen Zhang, Si-Jia Chen, Chun Yang, Peng-Gao L. Vitamin A Deficiency Exacerbates Gut Microbiota Dysbiosis and Cognitive Deficits in Amyloid Precursor Protein/Presenilin 1 Transgenic Mice. Frontiers in aging neuroscience. vol 13. 2021-11-19. PMID:34790112. |
our results show that vad aggravated the behavioral learning and memory deficits, reduced the retinol concentration in the liver and the serum, decreased the transcription of vitamin a (va)-related receptors and va-related enzymes in the cortex, increased amyloid-β peptides (aβ40 and aβ42) in the brain and gut, upregulate the translation of beta-site app-cleaving enzyme 1 (bace1) and phosphorylated tau in the cortex, and downregulate the expression of brain-derived neurotrophic factor (bdnf) and γ-aminobutyric acid (gaba) receptors in the cortex. |
2021-11-19 |
2023-08-13 |
mouse |
| Fei-Xue Wang, Ruo-Qi Tang, Jing Lv, Bin Xiao, Ying-Shun Li, Qing-Hua Ji. Norepinephrine in the dentate gyrus is involved in spatial learning and memory alteration induced by chronic restraint stress in aged rats. Neuroreport. vol 31. issue 18. 2021-11-15. PMID:33165197. |
compared with the control group, the basal level of norepinephrine, bdnf expression and creb activation in the dentate gyrus were increased, and the spatial learning and memory abilities were enhanced in crs rats. |
2021-11-15 |
2023-08-13 |
rat |
| Fei-Xue Wang, Ruo-Qi Tang, Jing Lv, Bin Xiao, Ying-Shun Li, Qing-Hua Ji. Norepinephrine in the dentate gyrus is involved in spatial learning and memory alteration induced by chronic restraint stress in aged rats. Neuroreport. vol 31. issue 18. 2021-11-15. PMID:33165197. |
furthermore, in crs rats, propranolol significantly decreased the spatial learning and memory abilities, and attenuated the fepsp response during mwm test, and the bdnf expression and creb activation in the dentate gyrus. |
2021-11-15 |
2023-08-13 |
rat |