| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Halonen, J Sivenius, R Miettinen, M Halmekytö, R Kauppinen, R Sinervirta, L Alakuijala, L Alhonen, E MacDonald, J Jänn. Elevated seizure threshold and impaired spatial learning in transgenic mice with putrescine overproduction in the brain. The European journal of neuroscience. vol 5. issue 9. 1994-02-15. PMID:8281326. |
we report that the transgenic mice with grossly elevated putrescine in all brain regions analysed (cortex, striatum, hippocampus and cerebellum) showed a significantly elevated seizure threshold to chemical and electrical stimuli, and impaired performance in spatial learning and memory tests. |
1994-02-15 |
2023-08-12 |
mouse |
| R E Clark, A A Zhang, D G Lavon. Reversible lesions of the cerebellar interpositus nucleus during acquisition and retention of a classically conditioned behavior. Behavioral neuroscience. vol 106. issue 6. 1993-02-01. PMID:1335267. |
in 2 experiments, the interpositus nucleus of the cerebellum was assessed for the plasticity associated with learning and memory of the nictitating membrane (nm) response by using local cooling as a reversible lesion technique. |
1993-02-01 |
2023-08-11 |
Not clear |
| R E Clark, A A Zhang, D G Lavon. Reversible lesions of the cerebellar interpositus nucleus during acquisition and retention of a classically conditioned behavior. Behavioral neuroscience. vol 106. issue 6. 1993-02-01. PMID:1335267. |
these results support the idea that the interpositus nucleus of the cerebellum is the critical locus for learning and memory of this classical cr. |
1993-02-01 |
2023-08-11 |
Not clear |
| J E Steinmetz, D G Lavond, D Ivkovich, C G Logan, R F Thompso. Disruption of classical eyelid conditioning after cerebellar lesions: damage to a memory trace system or a simple performance deficit? The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 12. issue 11. 1992-12-11. PMID:1432102. |
the lesion and recording studies have generally been cited as evidence that plasticity in the cerebellum is critically involved in the learning and memory of classically conditioned responses. |
1992-12-11 |
2023-08-11 |
Not clear |
| J E Steinmetz, D G Lavond, D Ivkovich, C G Logan, R F Thompso. Disruption of classical eyelid conditioning after cerebellar lesions: damage to a memory trace system or a simple performance deficit? The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 12. issue 11. 1992-12-11. PMID:1432102. |
this interpretation was recently challenged by welsh and harvey (1989a), who claimed that cerebellar lesions simply produced a performance deficit and speculated that the role of the cerebellum was not in learning and memory processes associated with the cr but only in performance of the eye blink response. |
1992-12-11 |
2023-08-11 |
Not clear |
| J E Steinmetz, D G Lavond, D Ivkovich, C G Logan, R F Thompso. Disruption of classical eyelid conditioning after cerebellar lesions: damage to a memory trace system or a simple performance deficit? The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 12. issue 11. 1992-12-11. PMID:1432102. |
presented here are three experiments that provide additional strong evidence for a critical role of the cerebellum in the learning and memory of the pavlovian cr. |
1992-12-11 |
2023-08-11 |
Not clear |
| R F Thompso. Are memory traces localized or distributed? Neuropsychologia. vol 29. issue 6. 1991-11-29. PMID:1944862. |
the cerebellum and its associated brain stem circuitry, on the other hand, does appear to be essential (necessary and sufficient) for learning and memory of the conditioned response. |
1991-11-29 |
2023-08-11 |
Not clear |
| T J O'Dell, E R Kandel, S G Gran. Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors. Nature. vol 353. issue 6344. 1991-11-07. PMID:1656271. |
because of the high amount of protein tyrosine kinases in hippocampus and cerebellum, two regions implicated in learning and memory, we examined the possible additional requirement of tyrosine kinase activity in ltp. |
1991-11-07 |
2023-08-11 |
Not clear |
| R F Thompso. Neural mechanisms of classical conditioning in mammals. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 329. issue 1253. 1990-12-12. PMID:1978361. |
the cerebellum and its associated brain-stem circuitry, on the other hand, does appear to be essential (necessary and sufficient) for learning and memory of the conditioned response. |
1990-12-12 |
2023-08-11 |
Not clear |
| D S Woodruff-Pak, J E Steinmetz, R F Thompso. Classical conditioning of rabbits 2-1/2 to 4 years old using mossy fiber stimulation as a CS. Neurobiology of aging. vol 9. issue 2. 1988-06-24. PMID:3374735. |
changes in the nervous system occurring more centrally in the cerebellum appear to affect learning and memory. |
1988-06-24 |
2023-08-11 |
Not clear |