| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Min-Kyoo Shin, Hong-Gi Kim, Kil-Lyong Ki. A novel brain-derived neurotrophic factor-modulating peptide attenuates Aβ1-42-induced neurotoxicity in vitro. Neuroscience letters. vol 595. 2015-10-20. PMID:25849526. |
brain-derived neurotrophic factor (bdnf) is a member of the neurotrophin family, which plays important roles in learning and memory formation and in protecting neurons from diverse neurotoxic insults, such as amyloid-beta (aβ). |
2015-10-20 |
2023-08-13 |
rat |
| Jennifer D Cooke, Hannah M Cavender, Hope K Lima, Lawrence M Grove. Antidepressants that inhibit both serotonin and norepinephrine reuptake impair long-term potentiation in hippocampus. Psychopharmacology. vol 231. issue 23. 2015-10-07. PMID:24781518. |
monoamine reuptake inhibitors can stimulate expression of brain-derived neurotrophic factor (bdnf) and alter long-term potentiation (ltp), a widely used model for the synaptic mechanisms that underlie memory formation. |
2015-10-07 |
2023-08-13 |
Not clear |
| Timothy J Jarome, Anderson A Butler, Jessica N Nichols, Natasha L Pacheco, Farah D Lubi. NF-κB mediates Gadd45β expression and DNA demethylation in the hippocampus during fear memory formation. Frontiers in molecular neuroscience. vol 8. 2015-10-07. PMID:26441517. |
additionally, local sirna-mediated knockdown of c-rel in area ca1 prevented fear conditioning-induced increases in gadd45β expression and bdnf dna demethylation, suggesting that c-rel containing nf-κb transcription factor complex is responsible for gadd45β regulation during memory formation. |
2015-10-07 |
2023-08-13 |
mouse |
| Caroline Ménard, Pierrette Gaudreau, Rémi Quirio. Signaling pathways relevant to cognition-enhancing drug targets. Handbook of experimental pharmacology. vol 228. 2015-09-28. PMID:25977080. |
first, we will discuss the role of the excitatory neurotransmitter glutamate and its receptors, downstream signaling effectors [e.g., calcium/calmodulin-dependent protein kinase ii (camkii), protein kinase c (pkc), extracellular signal-regulated kinases (erk), mammalian target of rapamycin (mtor), camp response element-binding protein (creb)], associated immediate early gene (e.g., homer 1a, arc and zif268), and growth factors [insulin-like growth factors (igfs) and brain-derived neurotrophic factor (bdnf)] in synaptic plasticity and memory formation. |
2015-09-28 |
2023-08-13 |
rat |
| S Deppermann, H Storchak, A J Fallgatter, A-C Ehli. Stress-induced neuroplasticity: (mal)adaptation to adverse life events in patients with PTSD--a critical overview. Neuroscience. vol 283. 2015-08-19. PMID:25193848. |
in this review article, we will outline the implications of stress exposure on memory formation involving the role of glucocorticoids and bdnf. |
2015-08-19 |
2023-08-13 |
Not clear |
| Elke Edelmann, Efrain Cepeda-Prado, Martin Franck, Petra Lichtenecker, Tanja Brigadski, Volkmar Leßman. Theta Burst Firing Recruits BDNF Release and Signaling in Postsynaptic CA1 Neurons in Spike-Timing-Dependent LTP. Neuron. vol 86. issue 4. 2015-08-12. PMID:25959732. |
this suggests that bdnf release during burst-like patterns of activity typically observed in vivo may play a crucial role during memory formation. |
2015-08-12 |
2023-08-13 |
Not clear |
| Erica D Smith, G Aleph Prieto, Liqi Tong, Ilse Sears-Kraxberger, Jeffrey D Rice, Oswald Steward, Carl W Cotma. Rapamycin and interleukin-1β impair brain-derived neurotrophic factor-dependent neuron survival by modulating autophagy. The Journal of biological chemistry. vol 289. issue 30. 2015-02-11. PMID:24917666. |
activation of mtor is necessary for the many beneficial effects of brain-derived neurotrophic factor (bdnf), including dendritic translation and memory formation in the hippocampus. |
2015-02-11 |
2023-08-13 |
rat |
| Simone Azevedo Bach, Letícia V de Siqueira, Alexandre P Müller, Jean P Oses, Andreia Quatrim, Tatiana Emanuelli, Lúcia Vinadé, Diogo O Souza, Júlia D Moreir. Dietary omega-3 deficiency reduces BDNF content and activation NMDA receptor and Fyn in dorsal hippocampus: implications on persistence of long-term memory in rats. Nutritional neuroscience. vol 17. issue 4. 2015-01-22. PMID:24621058. |
taken together, these data suggest that n-3 fatty acids influence the persistence of ltm by maintaining adequate levels of dha and bdnf as well as by influencing the activation of nr2b and fyn during the period of memory formation. |
2015-01-22 |
2023-08-12 |
rat |
| Min-Kyoo Shin, Hong-Gi Kim, Seung-Hyun Baek, Woo-Ram Jung, Dong-Ik Park, Jong-Sung Park, Dong-Gyu Jo, Kil-Lyong Ki. Neuropep-1 ameliorates learning and memory deficits in an Alzheimer's disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes reduction of amyloid beta plaques. Neurobiology of aging. vol 35. issue 5. 2014-10-06. PMID:24268884. |
abnormalities in the expression of brain-derived neurotrophic factor (bdnf), which plays an important role in learning and memory formation, have been reported in the brains of ad patients. |
2014-10-06 |
2023-08-12 |
mouse |
| Manuel Kuhn, Ana Popovic, Lukas Pezawa. Neuroplasticity and memory formation in major depressive disorder: an imaging genetics perspective on serotonin and BDNF. Restorative neurology and neuroscience. vol 32. issue 1. 2014-09-19. PMID:23603442. |
neuroplasticity and memory formation in major depressive disorder: an imaging genetics perspective on serotonin and bdnf. |
2014-09-19 |
2023-08-12 |
human |
| L Mou, B G Dias, H Gosnell, K J Ressle. Gephyrin plays a key role in BDNF-dependent regulation of amygdala surface GABAARs. Neuroscience. vol 255. 2014-08-14. PMID:24096136. |
our lab has previously found that bdnf activation of neurotrophic tyrosine kinase, receptor, type 2 (trkb) is required for fear memory formation and that gabaa receptor (gabaar) subunits and the gabaa clustering protein gephyrin are dynamically regulated during fear memory consolidation. |
2014-08-14 |
2023-08-12 |
mouse |
| Graciano Leal, Diogo Comprido, Carlos B Duart. BDNF-induced local protein synthesis and synaptic plasticity. Neuropharmacology. vol 76 Pt C. 2014-08-06. PMID:23602987. |
in this review we discuss the recent progress in understanding the mechanisms contributing to the short- and long-term regulation of the synaptic proteome by bdnf, and the role in synaptic plasticity, which is likely to influence learning and memory formation. |
2014-08-06 |
2023-08-12 |
Not clear |
| Alessio Travaglia, Diego La Mendola, Antonio Magrì, Adriana Pietropaolo, Vincenzo G Nicoletti, Giuseppe Grasso, Gaetano Malgieri, Roberto Fattorusso, Carla Isernia, Enrico Rizzarell. Zinc(II) interactions with brain-derived neurotrophic factor N-terminal peptide fragments: inorganic features and biological perspectives. Inorganic chemistry. vol 52. issue 19. 2014-05-08. PMID:24070197. |
brain-derived neurotrophic factor (bdnf) is a neurotrophin essential for neuronal differentiation, growth, and survival; it is involved in memory formation and higher cognitive functions. |
2014-05-08 |
2023-08-12 |
Not clear |
| Karlie A Intlekofer, Nicole C Berchtold, Melissa Malvaez, Anthony J Carlos, Susan C McQuown, Michael J Cunningham, Marcelo A Wood, Carl W Cotma. Exercise and sodium butyrate transform a subthreshold learning event into long-term memory via a brain-derived neurotrophic factor-dependent mechanism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 10. 2014-03-24. PMID:23615664. |
we demonstrate that exercise enables hippocampal-dependent learning in conditions that are normally subthreshold for encoding and memory formation, and depends on hippocampal induction of brain-derived neurotrophic factor (bdnf) as a key mechanism. |
2014-03-24 |
2023-08-12 |
mouse |
| Mahmoud A Alomari, Omar F Khabour, Karem H Alzoubi, Mohammad A Alzub. Forced and voluntary exercises equally improve spatial learning and memory and hippocampal BDNF levels. Behavioural brain research. vol 247. 2013-10-21. PMID:23499703. |
therefore, spatial learning and memory formation and brain-derived neurotrophic factor (bdnf) were examined in wister male rats after 6 weeks of either daily forced swimming, voluntary running exercises, or sedentary. |
2013-10-21 |
2023-08-12 |
rat |
| Hussam Jourdi, Mohamed Kabba. Acute BDNF treatment upregulates GluR1-SAP97 and GluR2-GRIP1 interactions: implications for sustained AMPA receptor expression. PloS one. vol 8. issue 2. 2013-09-03. PMID:23460828. |
brain-derived neurotrophic factor (bdnf) plays several prominent roles in synaptic plasticity and in learning and memory formation. |
2013-09-03 |
2023-08-12 |
Not clear |
| K Mizuno, E Dempster, J Mill, K P Gies. Long-lasting regulation of hippocampal Bdnf gene transcription after contextual fear conditioning. Genes, brain, and behavior. vol 11. issue 6. 2013-05-30. PMID:22574690. |
during contextual long-term memory formation brain-derived neurotrophic factor (bdnf) gene expression changes in conjunction with alterations of dna methylation in the bdnf gene. |
2013-05-30 |
2023-08-12 |
Not clear |
| Omar F Khabour, Karem H Alzoubi, Mahmoud A Alomari, Mohammad A Alzub. Changes in spatial memory and BDNF expression to simultaneous dietary restriction and forced exercise. Brain research bulletin. vol 90. 2013-05-30. PMID:23000024. |
in the current study, we investigated the combined effects of forced swimming exercise (fse) and every other day fasting (eodf) on spatial memory formation and on the levels of brain-derived neurotrophic factor (bdnf) in the hippocampus of wistar male rats. |
2013-05-30 |
2023-08-12 |
rat |
| Omar F Khabour, Karem H Alzoubi, Mahmoud A Alomari, Mohammad A Alzub. Changes in spatial memory and BDNF expression to simultaneous dietary restriction and forced exercise. Brain research bulletin. vol 90. 2013-05-30. PMID:23000024. |
the radial arm water maze (rawm) paradigm was used to assess changes in learning and memory formation, whereas elisa assay was used to measure bdnf protein levels. |
2013-05-30 |
2023-08-12 |
rat |
| Omar F Khabour, Karem H Alzoubi, Mahmoud A Alomari, Mohammad A Alzub. Changes in spatial memory and BDNF expression to simultaneous dietary restriction and forced exercise. Brain research bulletin. vol 90. 2013-05-30. PMID:23000024. |
results show that fse improved learning, short-term as well as long-term memory formation, and significantly increased bdnf protein in the hippocampus (p<0.05). |
2013-05-30 |
2023-08-12 |
rat |