| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Makoto Mizuno, Kiyofumi Yamada, Jue He, Akira Nakajima, Toshitaka Nabeshim. Involvement of BDNF receptor TrkB in spatial memory formation. Learning & memory (Cold Spring Harbor, N.Y.). vol 10. issue 2. 2003-07-25. PMID:12663749. |
involvement of bdnf receptor trkb in spatial memory formation. |
2003-07-25 |
2023-08-12 |
rat |
| Makoto Mizuno, Kiyofumi Yamada, Jue He, Akira Nakajima, Toshitaka Nabeshim. Involvement of BDNF receptor TrkB in spatial memory formation. Learning & memory (Cold Spring Harbor, N.Y.). vol 10. issue 2. 2003-07-25. PMID:12663749. |
here, we show that fyn is a key molecule linking the bdnf receptor trkb with nmda receptors, which play an important role in spatial memory formation in a radial arm maze. |
2003-07-25 |
2023-08-12 |
rat |
| Kevin D Broad, Mike L Mimmack, E Barry Keverne, Keith M Kendric. Increased BDNF and trk-B mRNA expression in cortical and limbic regions following formation of a social recognition memory. The European journal of neuroscience. vol 16. issue 11. 2003-03-25. PMID:12473084. |
brain-derived neurotrophic factor (bdnf) and its receptor, tyrosine receptor kinase (trk-b), play important roles in neural plasticity, long-term potentiation and memory formation. |
2003-03-25 |
2023-08-12 |
Not clear |
| W Tokuyama, H Okuno, T Hashimoto, Y Xin Li, Y Miyashit. BDNF upregulation during declarative memory formation in monkey inferior temporal cortex. Nature neuroscience. vol 3. issue 11. 2000-12-11. PMID:11036271. |
bdnf upregulation during declarative memory formation in monkey inferior temporal cortex. |
2000-12-11 |
2023-08-12 |
monkey |
| W Tokuyama, H Okuno, T Hashimoto, Y Xin Li, Y Miyashit. BDNF upregulation during declarative memory formation in monkey inferior temporal cortex. Nature neuroscience. vol 3. issue 11. 2000-12-11. PMID:11036271. |
the results suggest that bdnf contributes to reorganization of neural circuits for visual long-term memory formation in the primate. |
2000-12-11 |
2023-08-12 |
monkey |
| M Mizuno, K Yamada, A Olariu, H Nawa, T Nabeshim. Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 18. 2000-10-18. PMID:10995859. |
to clarify the causal relation between bdnf mrna expression and spatial memory formation, we examined the effects of antisense bdnf treatment on spatial learning and memory. |
2000-10-18 |
2023-08-12 |
rat |
| M J Schaaf, R M Sibug, R Duurland, M F Fluttert, M S Oitzl, E R De Kloet, E Vreugdenhi. Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training. Stress (Amsterdam, Netherlands). vol 3. issue 2. 2000-09-14. PMID:10938578. |
corticosterone and brain-derived neurotrophic factor (bdnf) have both been shown to be involved in spatial memory formation in rats. |
2000-09-14 |
2023-08-12 |
rat |
| V Lessman. Neurotrophin-dependent modulation of glutamatergic synaptic transmission in the mammalian CNS. General pharmacology. vol 31. issue 5. 1998-12-23. PMID:9809461. |
in addition, long-term potentiation (a potential cellular correlate for learning and memory formation in mammals) in the rodent hippocampus depends on endogenous supply of neurons with bdnf. |
1998-12-23 |
2023-08-12 |
Not clear |
| M Dragunow, P Hughes, S E Mason-Parker, P Lawlor, W C Abraha. TrkB expression in dentate granule cells is associated with a late phase of long-term potentiation. Brain research. Molecular brain research. vol 46. issue 1-2. 1997-08-05. PMID:9191102. |
thus, both bdnf and its receptor trkb are induced in granule cells by stimulation that produces durable ltp, suggesting that this neurotrophin and its receptor play an important role in memory formation and may be suitable targets for the development of cognitive-enhancing drugs in the treatment of diseases, such as alzheimer's. |
1997-08-05 |
2023-08-12 |
Not clear |