| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Judith R Homberg, Tommy Pattij, Mieke C W Janssen, Eric Ronken, Sietse F De Boer, Anton N M Schoffelmeer, Edwin Cuppe. Serotonin transporter deficiency in rats improves inhibitory control but not behavioural flexibility. The European journal of neuroscience. vol 26. issue 7. 2008-01-29. PMID:17897403. |
in conclusion, our data show that the absence of the sert affects aggression and inhibitory control, but not behavioural flexibility, characteristics that may reflect the trait-like consequences of constitutive changes in central 5-ht levels. |
2008-01-29 |
2023-08-12 |
rat |
| Jaap M Koolhaas, Sietse F de Boer, Bauke Buwalda, Kees van Reene. Individual variation in coping with stress: a multidimensional approach of ultimate and proximate mechanisms. Brain, behavior and evolution. vol 70. issue 4. 2007-11-27. PMID:17914253. |
the results so far show that proactive coping is characterized by a strong inhibitory control of the 5-ht neuron via its somatodendritic 5-ht(1a) autoreceptor. |
2007-11-27 |
2023-08-12 |
mouse |
| Xiao Jing Hu, Fu-Hua Wang, Carina Stenfors, Sven Ove Ogren, Jan Keh. Effects of the 5-HT1B receptor antagonist NAS-181 on extracellular levels of acetylcholine, glutamate and GABA in the frontal cortex and ventral hippocampus of awake rats: a microdialysis study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 17. issue 9. 2007-10-31. PMID:17234388. |
the present data suggest that ach neurotransmission in the fc and vhipp, the brain structures strongly implicated in cognitive function, is under tonic inhibitory control of 5-ht(1b) heteroreceptors localized at the cholinergic terminals in these areas. |
2007-10-31 |
2023-08-12 |
rat |
| Daniel Badauê-Passos, Andrea Godino, Alan Kim Johnson, Laura Vivas, José Antunes-Rodrigue. Dorsal raphe nuclei integrate allostatic information evoked by depletion-induced sodium ingestion. Experimental neurology. vol 206. issue 1. 2007-08-17. PMID:17544397. |
serotonin (5-ht) and the dorsal raphe nuclei (drn) have been implicated in the inhibitory control of salt intake (i.e., sodium appetite). |
2007-08-17 |
2023-08-12 |
rat |
| Sylvia Navailles, Delphine Moison, Dimitri Ryczko, Umberto Spampinat. Region-dependent regulation of mesoaccumbens dopamine neurons in vivo by the constitutive activity of central serotonin2C receptors. Journal of neurochemistry. vol 99. issue 4. 2007-01-09. PMID:17018023. |
these findings demonstrate that both vta and nac 5-ht(2c)rs participate in the inhibitory control exerted by 5-ht(2c)rs on accumbal da release, and that the nac shell may represent a primary action site for the ca of 5-ht(2c)rs. |
2007-01-09 |
2023-08-12 |
rat |
| Juan A Mico, Esther Berrocoso, Antonio Ortega-Alvaro, Juan Gibert-Rahola, M Olga Rojas-Corrale. The role of 5-HT1A receptors in research strategy for extensive pain treatment. Current topics in medicinal chemistry. vol 6. issue 18. 2006-11-30. PMID:17017970. |
different studies have shown that, by preventing this inhibitory control of serotonin release, it is possible to enhance the analgesic effect of drugs that increase serotonin levels (i.e. |
2006-11-30 |
2023-08-12 |
Not clear |
| Peter Whit. A background to acupuncture and its use in chronic painful musculoskeletal conditions. The journal of the Royal Society for the Promotion of Health. vol 126. issue 5. 2006-10-26. PMID:17004405. |
the science behind acupuncture is also explored in terms of its underlying mechanisms and includes pain gate, endogenous opioids, diffuse noxious inhibitory control, serotonin and bioelectricity as possible explanations. |
2006-10-26 |
2023-08-12 |
Not clear |
| R M M De Almeida, M M Rosa, D M Santos, D M Saft, Q Benini, K A Micze. 5-HT(1B) receptors, ventral orbitofrontal cortex, and aggressive behavior in mice. Psychopharmacology. vol 185. issue 4. 2006-09-28. PMID:16550387. |
one site of action for these drugs is the 5-ht(1b) receptors in the ventral orbitofrontal cortex (vo pfc), an area that has been implicated in the inhibitory control of behavior and is a terminal region for 5-ht projections. |
2006-09-28 |
2023-08-12 |
mouse |
| S C Walker, Y P Mikheenko, L D Argyle, T W Robbins, A C Robert. Selective prefrontal serotonin depletion impairs acquisition of a detour-reaching task. The European journal of neuroscience. vol 23. issue 11. 2006-09-28. PMID:16820002. |
this finding provides further support for the role of prefrontal serotonin in inhibitory control processes specifically in tasks sensitive to ofc dysfunction. |
2006-09-28 |
2023-08-12 |
monkey |
| Cliff H Summers, Wayne J Korzan, Jodi L Lukkes, Michael J Watt, Gina L Forster, Øyvind Øverli, Erik Höglund, Earl T Larson, Patrick J Ronan, John M Matter, Tangi R Summers, Kenneth J Renner, Neil Greenber. Does serotonin influence aggression? comparing regional activity before and during social interaction. Physiological and biochemical zoology : PBZ. vol 78. issue 5. 2006-05-02. PMID:16059845. |
serotonin is widely believed to exert inhibitory control over aggressive behavior and intent. |
2006-05-02 |
2023-08-12 |
Not clear |
| Samuel R Chamberlain, Ulrich Müller, Andrew D Blackwell, Luke Clark, Trevor W Robbins, Barbara J Sahakia. Neurochemical modulation of response inhibition and probabilistic learning in humans. Science (New York, N.Y.). vol 311. issue 5762. 2006-02-17. PMID:16469930. |
in healthy volunteers, inhibition of central noradrenaline reuptake improved response inhibition but had no effect on probabilistic learning, whereas inhibition of central serotonin reuptake impaired probabilistic learning with no effect on response inhibition. |
2006-02-17 |
2023-08-12 |
human |
| L Clark, J P Roiser, R Cools, D C Rubinsztein, B J Sahakian, T W Robbin. Stop signal response inhibition is not modulated by tryptophan depletion or the serotonin transporter polymorphism in healthy volunteers: implications for the 5-HT theory of impulsivity. Psychopharmacology. vol 182. issue 4. 2006-02-14. PMID:16163530. |
stop signal response inhibition is not modulated by tryptophan depletion or the serotonin transporter polymorphism in healthy volunteers: implications for the 5-ht theory of impulsivity. |
2006-02-14 |
2023-08-12 |
human |
| Katya Rubia, Francis Lee, Anthony J Cleare, Nigel Tunstall, Cynthia H Y Fu, Michael Brammer, Phillip McGuir. Tryptophan depletion reduces right inferior prefrontal activation during response inhibition in fast, event-related fMRI. Psychopharmacology. vol 179. issue 4. 2005-09-15. PMID:15887056. |
to test the hypothesis that 5-ht modulates neuro-cognitive brain activation during inhibitory control, we examined the effect of acute tryptophan depletion (atd), a dietary challenge, which has been shown to decrease 5-ht synthesis in the brain, on functional brain activation during a go/no-go task. |
2005-09-15 |
2023-08-12 |
human |
| Roshan Cools, Andrew Blackwell, Luke Clark, Lara Menzies, Sylvia Cox, Trevor W Robbin. Tryptophan depletion disrupts the motivational guidance of goal-directed behavior as a function of trait impulsivity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 7. 2005-08-09. PMID:15770237. |
serotonin (5-ht) is well known to affect the motivational properties of stimuli predictive of rewards as well as the inhibitory control of behavior. |
2005-08-09 |
2023-08-12 |
human |
| Roshan Cools, Andrew Blackwell, Luke Clark, Lara Menzies, Sylvia Cox, Trevor W Robbin. Tryptophan depletion disrupts the motivational guidance of goal-directed behavior as a function of trait impulsivity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 7. 2005-08-09. PMID:15770237. |
here, central 5-ht depletion was induced by the acute tryptophan (trp) depletion (atd) procedure in young healthy volunteers to examine the role of 5-ht in motivated action and prepotent response inhibition. |
2005-08-09 |
2023-08-12 |
human |
| Aminul Islam, Kevin S J Thompson, Saghir Akhtar, Sheila L Handle. Increased 5-HT2A receptor expression and function following central glucocorticoid receptor knockdown in vivo. European journal of pharmacology. vol 502. issue 3. 2005-03-08. PMID:15476747. |
these findings suggest that central 5-ht(2a) receptors are, directly or indirectly, under tonic inhibitory control by glucocorticoid receptor. |
2005-03-08 |
2023-08-12 |
rat |
| Shih-Jen Tsai, Chen-Jee Hong, Younger W-Y Yu, Tai-Jui Chen, Ying-Chieh Wang, Wen-Kuo Li. Association study of serotonin 1B receptor (A-161T) genetic polymorphism and suicidal behaviors and response to fluoxetine in major depressive disorder. Neuropsychobiology. vol 50. issue 3. 2004-10-19. PMID:15365222. |
serotonin 1b receptors (5-ht1b) are autoreceptors involved in the local inhibitory control of serotonin release, and have been suggested to play a role in the pathogenesis of major depressive disorder (mdd) and the antidepressant effects of the selective serotonin reuptake inhibitors in patients. |
2004-10-19 |
2023-08-12 |
Not clear |
| Benjamin Di Cara, Denise Samuel, Pascal Salin, Lydia Kerkerian-Le Goff, Annie Daszut. Serotonergic regulation of the GABAergic transmission in the rat basal ganglia. Synapse (New York, N.Y.). vol 50. issue 2. 2004-02-24. PMID:12923817. |
together, these results suggest that 5-ht afferents may exert a phasic inhibitory control on striatal gaba transmission. |
2004-02-24 |
2023-08-12 |
rat |
| Michelle D Lee, Guy A Kennett, Colin T Dourish, Peter G Clifto. 5-HT1B receptors modulate components of satiety in the rat: behavioural and pharmacological analyses of the selective serotonin1B agonist CP-94,253. Psychopharmacology. vol 164. issue 1. 2003-01-07. PMID:12373419. |
5-ht(1b) receptors are thought to be one of the receptor subtypes that mediate the inhibitory control of serotonin on food intake and satiety. |
2003-01-07 |
2023-08-12 |
rat |
| Candace E Hofmann, Wendy Simms, Wayne K Yu, Joanne Weinber. Prenatal ethanol exposure in rats alters serotonergic-mediated behavioral and physiological function. Psychopharmacology. vol 161. issue 4. 2002-12-23. PMID:12073165. |
animals prenatally exposed to ethanol (ethanol-exposed animals) exhibit physiological and behavioral abnormalities consistent with altered 5-hyrdroxytryptamine (5-ht) function including lack of response inhibition and increased anxiety and aggression. |
2002-12-23 |
2023-08-12 |
rat |