| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vincenzo Di Matteo, Marisa Cacchio, Camillo Di Giulio, Ennio Esposit. Role of serotonin(2C) receptors in the control of brain dopaminergic function. Pharmacology, biochemistry, and behavior. vol 71. issue 4. 2002-09-11. PMID:11888564. |
there is substantial evidence that the functional status of mesocorticolimbic dopaminergic (da) system originating in the ventral tegmental area (vta) is under a phasic and tonic inhibitory control by the serotonergic system, which acts by stimulating serotonin(2c) (5-ht(2c)) receptor subtypes. |
2002-09-11 |
2023-08-12 |
human |
| V Di Matteo, A De Blasi, C Di Giulio, E Esposit. Role of 5-HT(2C) receptors in the control of central dopamine function. Trends in pharmacological sciences. vol 22. issue 5. 2001-08-02. PMID:11339973. |
substantial evidence suggests that the functional status of the mesocorticolimbic dopamine (da) system originating in the ventral tegmental area is under a phasic and tonic inhibitory control by the 5-ht system that acts by stimulating 5-ht(2c) receptor subtypes. |
2001-08-02 |
2023-08-12 |
Not clear |
| J I Fratucci De Gobbi, L A De Luca, A K Johnson, J V Menan. Interaction of serotonin and cholecystokinin in the lateral parabrachial nucleus to control sodium intake. American journal of physiology. Regulatory, integrative and comparative physiology. vol 280. issue 5. 2001-05-17. PMID:11294747. |
the data suggest that functional interactions between 5-ht and cck in the lpbn may be important for exerting inhibitory control of nacl intake. |
2001-05-17 |
2023-08-12 |
rat |
| R Manhães de Castro, J M Barreto Medeiros, C Mendes da Silva, L M Ferreira, R C Guedes, J E Cabral Filho, J A Cost. Reduction of intraspecific aggression in adult rats by neonatal treatment with a selective serotonin reuptake inhibitor. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 34. issue 1. 2001-04-05. PMID:11151037. |
most studies suggest that serotonin exerts an inhibitory control on the aggression process. |
2001-04-05 |
2023-08-12 |
rat |
| b' T Koskinen, S Ruotsalainen, J Sirvi\\xc3\\xb. The 5-HT(2) receptor activation enhances impulsive responding without increasing motor activity in rats. Pharmacology, biochemistry, and behavior. vol 66. issue 4. 2000-11-07. PMID:10973510.' |
these data indicate that excessive activation of 5-ht(2a/2c) receptors interferes with response control rather than visual attention. |
2000-11-07 |
2023-08-12 |
rat |
| P Piguet, M E Stoeckel, R Schlichte. Synaptically released 5-HT modulates the activity of tonically discharging neuronal populations in the rostral ventral medulla (RVM). The European journal of neuroscience. vol 12. issue 8. 2000-10-19. PMID:10971610. |
the synaptic release of 5-ht was, itself, under an inhibitory control involving gabaa (gamma-aminobutyric acid) receptors. |
2000-10-19 |
2023-08-12 |
rat |
| V Di Matteo, G Di Giovanni, M Di Mascio, E Esposit. Biochemical and electrophysiological evidence that RO 60-0175 inhibits mesolimbic dopaminergic function through serotonin(2C) receptors. Brain research. vol 865. issue 1. 2000-07-21. PMID:10814735. |
taken together, these data confirm that central 5-ht system exerts an inhibitory control on the mesolimbic da system and that 5-ht(2c) receptors are involved in this effect. |
2000-07-21 |
2023-08-12 |
Not clear |
| b' T Koskinen, S Ruotsalainen, T Puumala, R Lappalainen, E Koivisto, P T M\\xc3\\xa4nnist\\xc3\\xb6, J Sirvi\\xc3\\xb. Activation of 5-HT2A receptors impairs response control of rats in a five-choice serial reaction time task. Neuropharmacology. vol 39. issue 3. 2000-05-16. PMID:10698013.' |
the present experiments investigated the effects of agents acting at serotonin (5-ht)-2 receptors on the performance of rats in a choice serial reaction time (5-csrt) task in order to examine the role of 5-ht2 receptors in the modulation of attention and response control. |
2000-05-16 |
2023-08-12 |
rat |
| A Evrard, A M Laporte, M Chastanet, R Hen, M Hamon, J Adrie. 5-HT1A and 5-HT1B receptors control the firing of serotoninergic neurons in the dorsal raphe nucleus of the mouse: studies in 5-HT1B knock-out mice. The European journal of neuroscience. vol 11. issue 11. 1999-12-28. PMID:10583471. |
altogether, these data indicate that in the mouse, the firing of 5-ht neurons in the dorsal raphe nucleus is under both an inhibitory control through 5-ht1a receptors and an excitatory influence through 5-ht1b receptors. |
1999-12-28 |
2023-08-12 |
mouse |
| T W Robbins, S Granon, J L Muir, F Durantou, A Harrison, B J Everit. Neural systems underlying arousal and attention. Implications for drug abuse. Annals of the New York Academy of Sciences. vol 846. 1998-07-31. PMID:9668410. |
thus, evidence in rats with selective neurochemical manipulations tested behaviorally using an analog of an attentional task developed for human subjects indicates that the coeruleo-cortical noradrenergic system is implicated in divided and selective attention, the basal forebrain cholinergic system in stimulus detection, the mesostriatal and mesolimbic dopaminergic systems in response speed and vigor, and the mesencephalic serotoninergic or 5-ht systems in response inhibition. |
1998-07-31 |
2023-08-12 |
human |
| b' T Puumala, J Sirvi\\xc3\\xb. Changes in activities of dopamine and serotonin systems in the frontal cortex underlie poor choice accuracy and impulsivity of rats in an attention task. Neuroscience. vol 83. issue 2. 1998-03-12. PMID:9460757.' |
these data indicate that frontal cortex dopamine and serotonin play an important role in the modulation of attention and response control. |
1998-03-12 |
2023-08-12 |
human |
| F J Bosker, A Klompmakers, H G Westenber. Postsynaptic 5-HT1A receptors mediate 5-hydroxytryptamine release in the amygdala through a feedback to the caudal linear raphe. European journal of pharmacology. vol 333. issue 2-3. 1998-01-05. PMID:9314028. |
using brain microdialysis, it was demonstrated that the release of 5-hydroxytryptamine (5-ht) in the central nucleus of the amygdala is under inhibitory control of somatodendritic and postsynaptic 5-ht1a receptors. |
1998-01-05 |
2023-08-12 |
Not clear |
| K J Simansk. Serotonergic control of the organization of feeding and satiety. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788474. |
studies in which serotonergic drugs were administered either systemically or directly into central sites have implicated 5-ht in the inhibitory control of feeding in mammals. |
1996-12-04 |
2023-08-12 |
rat |
| M V Ugrumov, A Trembleau, A Cala. Altered vasoactive intestinal polypeptide gene expression in the fetal rat suprachiasmatic nucleus following prenatal serotonin deficiency. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 12. issue 2. 1994-11-10. PMID:7942089. |
these data suggest that the vip gene expression in differentiating target neurons of the scn might be under serotonin inhibitory control during prenatal neurogenesis, prior to the onset of the serotoninergic neurotransmission. |
1994-11-10 |
2023-08-12 |
rat |
| S L Handley, J W McBlane, M A Critchley, K Njung'. Multiple serotonin mechanisms in animal models of anxiety: environmental, emotional and cognitive factors. Behavioural brain research. vol 58. issue 1-2. 1994-04-25. PMID:8136047. |
it is possible that cognitive factors may affect stimulus evaluation, and response inhibition by an aversive stimulus may be a special case of a wider role for serotonin in behavioural control. |
1994-04-25 |
2023-08-12 |
Not clear |
| P J Fletche. A comparison of the effects of dorsal or median raphe injections of 8-OH-DPAT in three operant tasks measuring response inhibition. Behavioural brain research. vol 54. issue 2. 1993-08-06. PMID:8323715. |
the 5-ht agonist 8-oh-dpat was then infused into either the dr or mr to suppress the activity of 5-ht neurons and the effects on response inhibition resulting from the omission of reward were measured. |
1993-08-06 |
2023-08-12 |
rat |
| P A Broderic. Cocaine: on-line analysis of an accumbens amine neural basis for psychomotor behavior. Pharmacology, biochemistry, and behavior. vol 40. issue 4. 1992-06-30. PMID:1816582. |
finally, acute cocaine administration is shown to produce a dose response inhibition of agoraphobia (fear), which is highly correlated (p = .983, p less than 0.01) with the opposing effects of cocaine on the accumbens biogenic amines, da and 5-ht. |
1992-06-30 |
2023-08-11 |
rat |
| A Castaño, J L Venero, J Cano, A Machad. Changes in the turnover of monoamines in prefrontal cortex of rats fed on vitamin E-deficient diet. Journal of neurochemistry. vol 58. issue 5. 1992-05-11. PMID:1560242. |
the opposing results found in da (increase) and 5-ht (decrease) turnover could provide further evidence for an inhibitory control of the serotoninergic ascending pathways to the dopaminergic system in the prefrontal cortex. |
1992-05-11 |
2023-08-11 |
rat |
| C A Wilson, I Gonzalez, F Farabollin. Behavioural effects in adulthood of neonatal manipulation of brain serotonin levels in normal and androgenized females. Pharmacology, biochemistry, and behavior. vol 41. issue 1. 1992-04-02. PMID:1531706. |
thus 5ht may normally exert an inhibitory control on the action of neonatal testosterone on exploration, motor activity and sexual behaviour. |
1992-04-02 |
2023-08-11 |
Not clear |
| V Coiro, M Passeri, L Capretti, G Speroni, C Davoli, C Marchesi, G Rossi, L Camellini, R Volpi, E Rot. Serotonergic control of TSH and PRL secretion in obese men. Psychoneuroendocrinology. vol 15. issue 4. 1991-05-23. PMID:2128415. |
to evaluate whether the inhibitory control of tsh and the stimulatory control of prolactin (prl) secretion exerted by endogenous serotonin was altered in obesity, 22 obese men and 10 normal controls were tested with trh (200 micrograms iv bolus) in the presence (experimental test) and absence (control test) of the serotonergic agonist fenfluramine (60 mg po 90 min before trh). |
1991-05-23 |
2023-08-11 |
human |