| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bernard G Schreurs, Deidre E O'Dell, Desheng Wan. The Role of Cerebellar Intrinsic Neuronal Excitability, Synaptic Plasticity, and Perineuronal Nets in Eyeblink Conditioning. Biology. vol 13. issue 3. 2024-03-27. PMID:38534469. |
the role of cerebellar intrinsic neuronal excitability, synaptic plasticity, and perineuronal nets in eyeblink conditioning. |
2024-03-27 |
2024-03-29 |
Not clear |
| Bernard G Schreurs, Deidre E O'Dell, Desheng Wan. The Role of Cerebellar Intrinsic Neuronal Excitability, Synaptic Plasticity, and Perineuronal Nets in Eyeblink Conditioning. Biology. vol 13. issue 3. 2024-03-27. PMID:38534469. |
here, we review how the cerebellum is involved in eyeblink conditioning-a particularly well-understood form of learning and memory-and focus on the role of perineuronal nets in intrinsic membrane excitability and synaptic plasticity that underlie eyeblink conditioning. |
2024-03-27 |
2024-03-29 |
Not clear |
| Guang-Gao Li, Ying-Han Xu, Ming-Ze Sun, Yan-Hua Bing, Wen-Zhe Jin, De-Lai Qi. Etomidate enhances cerebellar CF-PC synaptic plasticity through CB1 receptor/PKA cascade in vitro in mice. Neuroscience letters. 2024-03-16. PMID:38492880. |
etomidate enhances cerebellar cf-pc synaptic plasticity through cb1 receptor/pka cascade in vitro in mice. |
2024-03-16 |
2024-03-19 |
mouse |
| Chenyu Wang, Kimberly D Derderian, Elizabeth Hamada, Xujia Zhou, Andrew D Nelson, Henry Kyoung, Nadav Ahituv, Guy Bouvier, Kevin J Bende. Impaired cerebellar plasticity hypersensitizes sensory reflexes in SCN2A-associated ASD. Neuron. 2024-02-27. PMID:38412857. |
the cerebellum-dependent vestibulo-ocular reflex (vor), which helps maintain one's gaze during movement, was hypersensitized due to deficits in cerebellar synaptic plasticity. |
2024-02-27 |
2024-03-01 |
mouse |
| Zi-Hao Li, Bin Li, Xiao-Yang Zhang, Jing-Ning Zh. Neuropeptides and Their Roles in the Cerebellum. International journal of molecular sciences. vol 25. issue 4. 2024-02-24. PMID:38397008. |
given the nature of their diffuse distribution, peptidergic systems are generally assumed to exert a modulatory effect on the cerebellum via adaptively tuning neuronal excitability, synaptic transmission, and synaptic plasticity within cerebellar circuits. |
2024-02-24 |
2024-02-26 |
Not clear |
| Sho Kakizawa, Tomoko Arasaki, Ayano Yoshida, Ayami Sato, Yuka Takino, Akihito Ishigami, Takaaki Akaike, Shuichi Yanai, Shogo End. Essential role of ROS - 8-Nitro-cGMP signaling in long-term memory of motor learning and cerebellar synaptic plasticity. Redox biology. vol 70. 2024-02-10. PMID:38340634. |
essential role of ros - 8-nitro-cgmp signaling in long-term memory of motor learning and cerebellar synaptic plasticity. |
2024-02-10 |
2024-02-14 |
Not clear |
| J Solich, M Kolasa, A Faron-Górecka, P Pabian, K Latocha, A Korlatowicz, M Dziedzicka-Wasylewsk. Modulating Stress Susceptibility and Resilience: Insights from miRNA Manipulation and Neural Mechanisms in Mice. Molecular neurobiology. 2024-01-27. PMID:38280111. |
the expression changes of genes such as dgkq, bdnf, ntrk2, and pde4b in the mouse cerebellum suggested a link between cerebellar function, synaptic plasticity, and the differential stress responses observed in susceptible and resilient mice. |
2024-01-27 |
2024-01-30 |
mouse |
| J Solich, M Kolasa, A Faron-Górecka, P Pabian, K Latocha, A Korlatowicz, M Dziedzicka-Wasylewsk. Modulating Stress Susceptibility and Resilience: Insights from miRNA Manipulation and Neural Mechanisms in Mice. Molecular neurobiology. 2024-01-27. PMID:38280111. |
in summary, this research highlights the role of mmu-mir-1a-3p and mmu-mir-155-5p in regulating stress susceptibility and resilience in mice and suggests a connection between these micrornas, cerebellar function, and synaptic plasticity in the context of stress response. |
2024-01-27 |
2024-01-30 |
mouse |
| Hiroshi Mitoma, Shinji Kakei, Hirokazu Tanaka, Mario Mant. Morphological and Functional Principles Governing the Plasticity Reserve in the Cerebellum: The Cortico-Deep Cerebellar Nuclei Loop Model. Biology. vol 12. issue 11. 2023-11-25. PMID:37998034. |
clinical studies suggest (1) the involvement of synaptic plasticity in the cerebellar cortex for functional compensation and restoration, and (2) that the integrity of the cerebellar reserve requires the survival and functioning of cerebellar nuclei. |
2023-11-25 |
2023-11-28 |
Not clear |
| Yu Chen, Wei L. Rapid eye movement sleep contributes to the formation of new axonal varicosities in mouse cerebellar parallel fibers after motor training. Neuroscience letters. 2023-06-16. PMID:37327855. |
however, the synaptic structural dynamics between parallel and purkinje cells after motor training and the function of sleep in cerebellar synaptic plasticity remain unclear. |
2023-06-16 |
2023-08-14 |
mouse |
| Yue Zhao, Jiang Yao, Ying Shen, Li-Da S. Sepsis Impairs Purkinje Cell Functions and Motor Behaviors Through Microglia Activation. Cerebellum (London, England). 2023-02-15. PMID:36790600. |
our results show that the sepsis can activate microglia in the cerebellum and promote the secretion of inflammatory factor tnf-α, which increases intrinsic excitability and synaptic transmission of pcs, inhibits the synaptic plasticity of pcs, and impairs motor learning of mice. |
2023-02-15 |
2023-08-14 |
mouse |
| Tatjana Surdin, Bianca Preissing, Lennard Rohr, Michelle Grömmke, Hanna Böke, Maike Barcik, Zohre Azimi, Dirk Jancke, Stefan Herlitze, Melanie D Mark, Ida Sivek. Optogenetic activation of mGluR1 signaling in the cerebellum induces synaptic plasticity. iScience. vol 26. issue 1. 2023-01-12. PMID:36632066. |
optogenetic activation of mglur1 signaling in the cerebellum induces synaptic plasticity. |
2023-01-12 |
2023-08-14 |
Not clear |
| Jonathan Mapelli, Giulia Maria Boiani, Egidio D'Angelo, Albertino Bigiani, Daniela Gandolf. Long-Term Synaptic Plasticity Tunes the Gain of Information Channels through the Cerebellum Granular Layer. Biomedicines. vol 10. issue 12. 2022-12-23. PMID:36551941. |
long-term synaptic plasticity tunes the gain of information channels through the cerebellum granular layer. |
2022-12-23 |
2023-08-14 |
Not clear |
| A Barri, M T Wiechert, M Jazayeri, D A DiGregori. Synaptic basis of a sub-second representation of time in a neural circuit model. Nature communications. vol 13. issue 1. 2022-12-22. PMID:36550115. |
we leveraged the well-defined architecture of the cerebellum, a brain region known to support temporally precise actions, to explore theoretically whether the experimentally observed diversity of short-term synaptic plasticity (stp) at the input layer could generate neural dynamics sufficient for sub-second temporal learning. |
2022-12-22 |
2023-08-14 |
Not clear |
| Hiroshi Mitoma, Shinji Kakei, Mario Mant. Development of Cerebellar Reserve. Cells. vol 11. issue 19. 2022-10-14. PMID:36230975. |
this unique cerebellar ability is attributed to various forms of synaptic plasticity that incorporate multimodal and redundant cerebellar inputs, two major features of the cerebellar circuitry. |
2022-10-14 |
2023-08-14 |
Not clear |
| Niceto R Luque, Francisco Naveros, Ignacio Abadía, Eduardo Ros, Angelo Arle. Electrical coupling regulated by GABAergic nucleo-olivary afferent fibres facilitates cerebellar sensory-motorsensory-motor adaptation. Neural networks : the official journal of the International Neural Network Society. vol 155. 2022-09-18. PMID:36116334. |
the model incorporates spike-based synaptic plasticity at multiple cerebellar sites and an electrically-coupled olivary system. |
2022-09-18 |
2023-08-14 |
Not clear |
| Yuta Miura, Kento Ojima, Shigeki Kiyonak. [Coordination chemogenetics for regulation of glutamate receptors in neuron]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 157. issue 5. 2022-09-01. PMID:36047155. |
a palladium (pd) complex successfully activated mglu1 in mglu1(n264h) knock-in mice, demonstrating that endogenous mglu1 activation is sufficient to evoke a key cellular mechanism of synaptic plasticity that underlies motor learning in the cerebellum. |
2022-09-01 |
2023-08-14 |
mouse |
| Anmol Bhandari, Shikha Kalotra, Payal Bajaj, Aditya Sunkaria, Gurcharan Kau. Dietary intervention with Tinospora cordifolia improved aging-related decline in locomotor coordination and cerebellar cell survival and plasticity in female rats. Biogerontology. 2022-06-29. PMID:35767131. |
further, due to its multicomponent nature tcp was found to target the expression of various markers of neuroinflammation, apoptosis, cell survival, and synaptic plasticity in the cerebellum region. |
2022-06-29 |
2023-08-14 |
rat |
| Guang-Gao Li, Chun-Jian Piao, Peng Wan, Shu-Yu Li, Yu-Xuan Wei, Guo-Jun Zhao, Wen-Yuan Wu, Lan Hong, Chun-Ping Chu, De-Lai Qi. Opposing actions of CRF-R1 and CB1 receptor on facial stimulation-induced MLI-PC plasticity in mouse cerebellar cortex. BMC neuroscience. vol 23. issue 1. 2022-06-26. PMID:35754033. |
cerebellar crf is released by afferents from inferior olivary neurons and other brainstem nuclei in response to stressful challenges, and contributes to modulation of synaptic plasticity and motor learning behavior via its receptors. |
2022-06-26 |
2023-08-14 |
mouse |
| Kento Ojima, Wataru Kakegawa, Tokiwa Yamasaki, Yuta Miura, Masayuki Itoh, Yukiko Michibata, Ryou Kubota, Tomohiro Doura, Eriko Miura, Hiroshi Nonaka, Seiya Mizuno, Satoru Takahashi, Michisuke Yuzaki, Itaru Hamachi, Shigeki Kiyonak. Coordination chemogenetics for activation of GPCR-type glutamate receptors in brain tissue. Nature communications. vol 13. issue 1. 2022-06-17. PMID:35710788. |
a palladium complex showing low cytotoxicity successfully activated mglu1 in mglu1(n264h) knock-in mice, revealing that activation of endogenous mglu1 is sufficient to evoke the critical cellular mechanism of synaptic plasticity, a basis of motor learning in the cerebellum. |
2022-06-17 |
2023-08-14 |
mouse |