| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cristina V Dieni, Jacqueline A Sullivan, Mario Faralli, Samuele Contemori, Andrea Biscarini, Vito E Pettorossi, Roberto Panich. 17 beta-estradiol synthesis modulates cerebellar dependent motor memory formation in adult male rats. Neurobiology of learning and memory. vol 155. 2019-09-23. PMID:30125696. |
indeed, e2 modulates cerebellar parallel fiber-purkinje cell synaptic plasticity that underlies encoding of vor adaptation. |
2019-09-23 |
2023-08-13 |
rat |
| Paula A Zamudio-Bulcock, Gregg E Homanics, John J Woodwar. Loss of Ethanol Inhibition of N-Methyl-D-Aspartate Receptor-Mediated Currents and Plasticity of Cerebellar Synapses in Mice Expressing the GluN1(F639A) Subunit. Alcoholism, clinical and experimental research. vol 42. issue 4. 2019-08-12. PMID:29323417. |
in this study, we examined cerebellar nmda responses and nmda-mediated synaptic plasticity in wild-type (wt) and glun1(f639a) mice. |
2019-08-12 |
2023-08-13 |
mouse |
| Soichi Nagao, Takeru Hond. [Artificial Intelligence and Cerebellar Motor Learning]. Brain and nerve = Shinkei kenkyu no shinpo. vol 71. issue 7. 2019-08-07. PMID:31289241. |
ten years later, ito found the synaptic plasticity of long-term depression at cerebellar purkinje cell synapses, which underlies cerebellar learning. |
2019-08-07 |
2023-08-13 |
Not clear |
| Niceto R Luque, Francisco Naveros, Richard R Carrillo, Eduardo Ros, Angelo Arle. Spike burst-pause dynamics of Purkinje cells regulate sensorimotor adaptation. PLoS computational biology. vol 15. issue 3. 2019-04-29. PMID:30860991. |
the model captures the cerebellar microcircuit properties and it incorporates spike-based synaptic plasticity at multiple cerebellar sites. |
2019-04-29 |
2023-08-13 |
Not clear |
| Rui Li, Qi Li, Xiao-Lei Chu, Tao Tao, Lan Li, Cheng-Qi He, Fang-You Ga. Trace eyeblink conditioning is associated with changes in synaptophysin immunoreactivity in the cerebellar interpositus nucleus in guinea pigs. Bioscience reports. vol 38. issue 3. 2019-03-15. PMID:29051391. |
our data suggest that the increase in syn expression links to synaptic plasticity changes in the cerebellar in and provides a histological substrate in the in relating to tebc training. |
2019-03-15 |
2023-08-13 |
Not clear |
| Cristina V Dieni, Aldo Ferraresi, Jacqueline A Sullivan, Sivarosa Grassi, Vito E Pettorossi, Roberto Panich. Acute inhibition of estradiol synthesis impacts vestibulo-ocular reflex adaptation and cerebellar long-term potentiation in male rats. Brain structure & function. vol 223. issue 2. 2019-02-25. PMID:28942480. |
we hypothesized that e2 impacts vor adaptation by affecting cerebellar synaptic plasticity at the parallel fiber-purkinje cell (pf) synapse. |
2019-02-25 |
2023-08-13 |
rat |
| Cristina V Dieni, Aldo Ferraresi, Jacqueline A Sullivan, Sivarosa Grassi, Vito E Pettorossi, Roberto Panich. Acute inhibition of estradiol synthesis impacts vestibulo-ocular reflex adaptation and cerebellar long-term potentiation in male rats. Brain structure & function. vol 223. issue 2. 2019-02-25. PMID:28942480. |
we also assessed the effect of letrozole on synaptic plasticity at the pf synapse in vitro, using cerebellar slices from male rats. |
2019-02-25 |
2023-08-13 |
rat |
| Cristina V Dieni, Aldo Ferraresi, Jacqueline A Sullivan, Sivarosa Grassi, Vito E Pettorossi, Roberto Panich. Acute inhibition of estradiol synthesis impacts vestibulo-ocular reflex adaptation and cerebellar long-term potentiation in male rats. Brain structure & function. vol 223. issue 2. 2019-02-25. PMID:28942480. |
these findings suggest that e2 might regulate changes in vor adaptation by acting locally on cerebellar and extra-cerebellar synaptic plasticity sites. |
2019-02-25 |
2023-08-13 |
rat |
| Takamitsu Sano, Ayako Kohyama-Koganeya, Masami O Kinoshita, Tetsuya Tatsukawa, Chika Shimizu, Eriko Oshima, Kazuyuki Yamada, Tung Dinh Le, Takumi Akagi, Koujiro Tohyama, Soichi Nagao, Yoshio Hirabayash. Loss of GPRC5B impairs synapse formation of Purkinje cells with cerebellar nuclear neurons and disrupts cerebellar synaptic plasticity and motor learning. Neuroscience research. vol 136. 2018-11-09. PMID:29481883. |
loss of gprc5b impairs synapse formation of purkinje cells with cerebellar nuclear neurons and disrupts cerebellar synaptic plasticity and motor learning. |
2018-11-09 |
2023-08-13 |
mouse |
| Alice Geminiani, Claudia Casellato, Alberto Antonietti, Egidio D'Angelo, Alessandra Pedrocch. A Multiple-Plasticity Spiking Neural Network Embedded in a Closed-Loop Control System to Model Cerebellar Pathologies. International journal of neural systems. vol 28. issue 5. 2018-10-29. PMID:28264639. |
the model was modified to reproduce three different damages of the cerebellar cortex: (i) a loss of the main output neurons (purkinje cells), (ii) a lesion to the main cerebellar afferents (mossy fibers), and (iii) a damage to a major mechanism of synaptic plasticity (long term depression). |
2018-10-29 |
2023-08-13 |
human |
| Roberto Russo, Fabio Cattaneo, Pellegrino Lippiello, Claudia Cristiano, Fabio Zurlo, Martina Castaldo, Carlo Irace, Tiziana Borsello, Rita Santamaria, Rosario Ammendola, Antonio Calignano, Maria Concetta Miniac. Motor coordination and synaptic plasticity deficits are associated with increased cerebellar activity of NADPH oxidase, CAMKII, and PKC at preplaque stage in the TgCRND8 mouse model of Alzheimer's disease. Neurobiology of aging. vol 68. 2018-10-16. PMID:29602494. |
motor coordination and synaptic plasticity deficits are associated with increased cerebellar activity of nadph oxidase, camkii, and pkc at preplaque stage in the tgcrnd8 mouse model of alzheimer's disease. |
2018-10-16 |
2023-08-13 |
mouse |
| Roberto Russo, Fabio Cattaneo, Pellegrino Lippiello, Claudia Cristiano, Fabio Zurlo, Martina Castaldo, Carlo Irace, Tiziana Borsello, Rita Santamaria, Rosario Ammendola, Antonio Calignano, Maria Concetta Miniac. Motor coordination and synaptic plasticity deficits are associated with increased cerebellar activity of NADPH oxidase, CAMKII, and PKC at preplaque stage in the TgCRND8 mouse model of Alzheimer's disease. Neurobiology of aging. vol 68. 2018-10-16. PMID:29602494. |
patch-clamp recordings performed on cerebellar slices of transgenic mice showed synaptic plasticity deficit and loss of noradrenergic modulation at parallel fiber-purkinje cell synapse suggesting an early dysfunction of the cerebellar circuitry due to amyloid precursor protein overexpression. |
2018-10-16 |
2023-08-13 |
mouse |
| Anna M Lavezzi, Stefano Ferrero, Debora Lattuada, Francesco Piscioli, Graziella Alfonsi, Luigi Matturr. Pathobiological expression of the brain-derived neurotrophic factor (BDNF) in cerebellar cortex of sudden fetal and infant death victims. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 66. 2018-09-07. PMID:29174061. |
brain-derived neurotrophic factor (bdnf), a neurotrophin of the central nervous system, is able to regulate neuronal differentiation and modulate synaptic plasticity, being particularly involved in the development of the cerebellar cortical structure. |
2018-09-07 |
2023-08-13 |
human |
| Eriola Hoxha, Pellegrino Lippiello, Bibiana Scelfo, Filippo Tempia, Mirella Ghirardi, Maria Concetta Miniac. Maturation, Refinement, and Serotonergic Modulation of Cerebellar Cortical Circuits in Normal Development and in Murine Models of Autism. Neural plasticity. vol 2017. 2018-05-24. PMID:28894610. |
in the adult cerebellar cortex, many developmental mechanisms persist but play different roles, such as supporting synaptic plasticity during learning and formation of cerebellar memory traces. |
2018-05-24 |
2023-08-13 |
Not clear |
| Takeyuki Sugawara, Chihiro Hisatsune, Hiroyuki Miyamoto, Naoko Ogawa, Katsuhiko Mikoshib. Regulation of spinogenesis in mature Purkinje cells via mGluR/PKC-mediated phosphorylation of CaMKIIβ. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 26. 2018-05-09. PMID:28607044. |
dendritic spines of purkinje cells form excitatory synapses with parallel fiber terminals, which are the primary sites for cerebellar synaptic plasticity. |
2018-05-09 |
2023-08-13 |
Not clear |
| Joseph M Pochiro, Derick H Lindquis. Central amygdala lesions inhibit pontine nuclei acoustic reactivity and retard delay eyeblink conditioning acquisition in adult rats. Learning & behavior. vol 44. issue 2. 2018-05-04. PMID:26486933. |
while cerebellar synaptic plasticity is necessary for successful ebc, the amygdala is proposed to enhance eyeblink cr acquisition. |
2018-05-04 |
2023-08-13 |
human |
| Joseph M Pochiro, Derick H Lindquis. Central amygdala lesions inhibit pontine nuclei acoustic reactivity and retard delay eyeblink conditioning acquisition in adult rats. Learning & behavior. vol 44. issue 2. 2018-05-04. PMID:26486933. |
results suggest delay ebc proceeds through three stages: in stage one the amygdala rapidly excites diffuse fear responses and pn acoustic reactivity, facilitating cerebellar synaptic plasticity and the development of eyeblink crs in stage two, leading, in stage three, to a diminution or stabilization of conditioned fear responding. |
2018-05-04 |
2023-08-13 |
human |
| Adam B Steinmetz, John H Freema. Cannabinoid modulation of memory consolidation within the cerebellum. Neurobiology of learning and memory. vol 136. 2018-02-15. PMID:27818269. |
the cerebellum contains a high density of cannabinoid receptors and manipulations of cannabinoid receptors affect synaptic plasticity within the cerebellar cortex. |
2018-02-15 |
2023-08-13 |
rat |
| Changzheng Zhang, Peiling Zhou, Tifei Yua. The cholinergic system in the cerebellum: from structure to function. Reviews in the neurosciences. vol 27. issue 8. 2018-01-02. PMID:27559688. |
in this report, we review the cerebellar cholinergic system, including cholinergic origins and innervations, acetylcholine receptor expression and distributions, cholinergic modulations of neuronal firing and synaptic plasticity, the cholinergic role in cerebellar-mediated integral functions, and cholinergic changes during development and aging. |
2018-01-02 |
2023-08-13 |
Not clear |
| Xian Xiao, Qiang-Hua He, Li-Yan Yu, Song-Qing Wang, Yang Li, Hua Yang, Ai-Hua Zhang, Xiao-Hong Ma, Yu-Jie Peng, Bing Che. Structure-based optimization of salt-bridge network across the complex interface of PTPN4 PDZ domain with its peptide ligands in neuroglioma. Computational biology and chemistry. vol 66. 2017-11-09. PMID:27923202. |
the ptp non-receptor type 4 (ptpn4) is an important regulator protein in learning, spatial memory and cerebellar synaptic plasticity; targeting the pdz domain of ptpn4 has become as attractive therapeutic strategy for human neuroglioma. |
2017-11-09 |
2023-08-13 |
human |