| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ali Mamivand, Shiva Bayat, Abolfazl Maghrouni, Sasan Shabani, Alireza Khoshnevisan, Hiva Saffar, Mina Tabriz. Data mining of bulk and single-cell RNA sequencing introduces OBI1-AS1 as an astrocyte marker with possible role in glioma recurrence and progression. Clinical epigenetics. vol 14. issue 1. 2022-03-09. PMID:35260196. |
our study indicated that lncrnas, like obi1-as1, could be extremely precise in identifying the astrocyte cluster in the single-cell transcriptome and demonstrating superiority to well-established astrocyte markers such as gfap, s100b, aldh1l1, and aqp4. |
2022-03-09 |
2023-08-13 |
Not clear |
| Adriana Fernanda Kuckartz Vizuete, Ben Hur Mussulini, Kamila Cagliari Zenki, Suelen Baggio, Amanda Pasqualotto, Denis Broock Rosemberg, Maurício Reis Bogo, Diogo Lösch de Oliveira, Eduardo Pacheco Ric. Prolonged ethanol exposure alters glutamate uptake leading to astrogliosis and neuroinflammation in adult zebrafish brain. Neurotoxicology. vol 88. 2021-12-02. PMID:34728274. |
here, we explore the effects of prolonged etoh exposure on the glutamatergic uptake system and its relationship with astroglial markers (gfap and s100b), neuroinflammation (il-1β and tnf-α), and brain derived neurotrophic factor (bdnf) levels in the cns of adult zebrafish. |
2021-12-02 |
2023-08-13 |
zebrafish |
| Jinhan Yang, Tong Wang, Xiaoxia Jin, Gaoyang Wang, Fenghong Zhao, Yaping Ji. Roles of Crosstalk between Astrocytes and Microglia in Triggering Neuroinflammation and Brain Edema Formation in 1,2-Dichloroethane-Intoxicated Mice. Cells. vol 10. issue 10. 2021-11-25. PMID:34685627. |
the present research revealed, for the first time, that subacute intoxication with 1,2-dce might provoke the proinflammatory polarization of microglia, and pretreatment with minocycline, a specific inhibitor of microglial activation, may attenuate the enhanced protein levels of ionized calcium-binding adapter molecule1 (iba-1), cluster of differentiation 11b (cd11b), glial fibrillary acidic protein (gfap), soluble calcium-binding protein 100b (s100b), tumor necrosis factor α (tnf-α), interleukin 6 (il-6), inducible nitric oxide synthase (inos), vascular cell adhesion molecule-1 (vcam-1), intercellular adhesion molecule-1 (icam-1), matrix metalloproteinase-9 (mmp-9), toll-like receptor 4 (tlr4), myd88, and p-p65, and ameliorate the suppressed protein expression levels of occludin and claudin 5; we also observed changes in water content and made pathological observations on edema in the brains of 1,2-dce-intoxicated mice. |
2021-11-25 |
2023-08-13 |
mouse |
| Frederick Korley, Qi Pauls, Sharon D Yeatts, Courtney Marie Cora Jones, Emily Corbett-Valade, Robert Silbergleit, Michael Frankel, William Barsan, Nathan D Cahill, Jeffrey J Bazarian, David W Wrigh. Progesterone Treatment Does Not Decrease Serum Levels of Biomarkers of Glial and Neuronal Cell Injury in Moderate and Severe Traumatic Brain Injury Subjects: A Secondary Analysis of the Progesterone for Traumatic Brain Injury, Experimental Clinical Treatment (ProTECT) III Trial. Journal of neurotrauma. vol 38. issue 14. 2021-11-18. PMID:33319651. |
we quantified brain cell death using serum levels of biomarkers of glial and neuronal cell death (glial fibrillary acidic protein [gfap], ubiquitin carboxy-terminal hydrolase-l1 [uch-l1], s100 calcium-binding protein b [s100b], and alpha ii spectrin breakdown product 150 [sbdp]) in the biomarkers of injury and outcome-progesterone for traumatic brain injury, experimental clinical treatment (bio-protect) study. |
2021-11-18 |
2023-08-13 |
human |
| David O Okonkwo, Ross C Puffer, Ava M Puccio, Esther L Yuh, John K Yue, Ramon Diaz-Arrastia, Frederick K Korley, Kevin K W Wang, Xiaoying Sun, Sabrina R Taylor, Pratik Mukherjee, Amy J Markowitz, Sonia Jain, Geoffrey T Manle. Point-of-Care Platform Blood Biomarker Testing of Glial Fibrillary Acidic Protein versus S100 Calcium-Binding Protein B for Prediction of Traumatic Brain Injuries: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study. Journal of neurotrauma. vol 37. issue 23. 2021-11-05. PMID:32854584. |
glial fibrillary acidic protein (gfap) is cleared by the food and drug administration (fda) to determine need for head computed tomography (ct) within 12 h after mild traumatic brain injury (tbi) (glasgow coma score [gcs] 13-15); s100 calcium-binding protein b (s100b) serves this function in europe. |
2021-11-05 |
2023-08-13 |
human |
| Fani Pujol-Calderón, Henrik Zetterberg, Erik Portelius, Pia Löwhagen Hendén, Alexandros Rentzos, Jan-Erik Karlsson, Kina Höglund, Kaj Blennow, Lars E Rosengre. Prediction of Outcome After Endovascular Embolectomy in Anterior Circulation Stroke Using Biomarkers. Translational stroke research. 2021-10-06. PMID:33723754. |
in this study, we investigated the use of the brain damage biomarkers tau, nfl, nse, gfap, and s100b to understand the progression of nervous tissue damage and their relationship to outcome in such stroke after endovascular treatment. |
2021-10-06 |
2023-08-13 |
Not clear |
| Lucas Dos Reis Izolan, Douglas Marques da Silva, Helena Beatriz Larrosa Oliveira, Janaína Lucas de Oliveira Salomon, Caroline Portela Peruzzi, Solange C Garcia, Eliane Dallegrave, Caroline Zanotto, Elaine Elisabetsky, Carlos Alberto Gonçalves, Marcelo Dutra Arbo, Eduardo Luis Konrath, Mirna Bainy Lea. Sintocalmy, a Passiflora incarnata Based Herbal, Attenuates Morphine Withdrawal in Mice. Neurochemical research. vol 46. issue 5. 2021-09-27. PMID:33544325. |
in addition, glial fibrillary acidic protein (gfap) and s100 calcium-binding protein b (s100b) levels were assessed in the frontal cortex and hippocampus, and dna damage was verified on blood cells. |
2021-09-27 |
2023-08-13 |
mouse |
| Lucas Dos Reis Izolan, Douglas Marques da Silva, Helena Beatriz Larrosa Oliveira, Janaína Lucas de Oliveira Salomon, Caroline Portela Peruzzi, Solange C Garcia, Eliane Dallegrave, Caroline Zanotto, Elaine Elisabetsky, Carlos Alberto Gonçalves, Marcelo Dutra Arbo, Eduardo Luis Konrath, Mirna Bainy Lea. Sintocalmy, a Passiflora incarnata Based Herbal, Attenuates Morphine Withdrawal in Mice. Neurochemical research. vol 46. issue 5. 2021-09-27. PMID:33544325. |
no alterations were found in gfap levels, however sme 50 mg/kg prevented the s100b increase in the frontal cortex and dna damage. |
2021-09-27 |
2023-08-13 |
mouse |
| Jadwiga Jaworska-Adamu, Aleksandra Krawczyk, Karol Rycerz, Marcin Golynsk. Reactivity of astrocytes in hippocampal CA1 area in rats after administration of habanero peppers. Folia histochemica et cytobiologica. vol 59. issue 1. 2021-08-30. PMID:33502751. |
their reactivity is manifested by an increase in glial fibrillary acidic protein (gfap) and s100b protein levels, hypertrophy and hyperplasia. |
2021-08-30 |
2023-08-13 |
rat |
| Jadwiga Jaworska-Adamu, Aleksandra Krawczyk, Karol Rycerz, Marcin Golynsk. Reactivity of astrocytes in hippocampal CA1 area in rats after administration of habanero peppers. Folia histochemica et cytobiologica. vol 59. issue 1. 2021-08-30. PMID:33502751. |
the aim of the study was to analyse immunoreactive gfap (gfap-ir) and s100b (s100b-ir) astrocytes of hippocampal ca1 area in adult rats intragastrically (i.g.) |
2021-08-30 |
2023-08-13 |
rat |
| Maike Michel, Bernd L Fiebich, Hanna Kuzior, Sophie Meixensberger, Benjamin Berger, Simon Maier, Kathrin Nickel, Kimon Runge, Dominik Denzel, Benjamin Pankratz, Miriam A Schiele, Katharina Domschke, Ludger Tebartz van Elst, Dominique Endre. Increased GFAP concentrations in the cerebrospinal fluid of patients with unipolar depression. Translational psychiatry. vol 11. issue 1. 2021-07-14. PMID:34021122. |
therefore, the aim of the current study was to examine gfap and s100b levels in the csf of patients with major depression to better understand their role in affective disorders. |
2021-07-14 |
2023-08-13 |
Not clear |
| J L Cordeiro, J D Neves, A F Vizuete, D Aristimunha, T A Pedroso, E F Sanches, C A Gonçalves, C A Nett. Arundic Acid (ONO-2506), an Inhibitor of S100B Protein Synthesis, Prevents Neurological Deficits and Brain Tissue Damage Following Intracerebral Hemorrhage in Male Wistar Rats. Neuroscience. vol 440. 2021-05-14. PMID:32474054. |
firstly, aa was injected at different doses (0.02, 0.2, 2 and 20 μg/μl) in the left lateral ventricle in order to observe which dose would decrease gfap and s100b striatal levels in non-injured rats. |
2021-05-14 |
2023-08-13 |
rat |
| Tawaun A Lucas, Li Zhu, Marion S Buckwalte. Spleen glia are a transcriptionally unique glial subtype interposed between immune cells and sympathetic axons. Glia. vol 69. issue 7. 2021-05-11. PMID:33710690. |
we establish that spleen glia can be visualized using both immunohistochemistry for s100b and gfap and with a reporter mouse. |
2021-05-11 |
2023-08-13 |
mouse |
| Tomas Vedin, Henrik Bergenfeldt, Emanuel Holmström, Jakob Lundager-Forberg, Marcus Edelhamr. Microwave scan and brain biomarkers to rule out intracranial hemorrhage: study protocol of a planned prospective study (MBI01). European journal of trauma and emergency surgery : official publication of the European Trauma Society. 2021-05-04. PMID:33944977. |
the aim of this planned study is to evaluate the ability of a cranial microwave scanner in conjunction with nine brain biomarkers (aβ40, aβ42, gfap, h-fabp, s100b, nf-l, nse, uch-l1 and il-10) to detect and rule out traumatic intracranial hemorrhage in an emergency department setting. |
2021-05-04 |
2023-08-13 |
Not clear |
| E V N Beshay, S A El-Refai, G S Sadek, A A Elbadry, F H Shalan, A F Afif. Mesenchymal stem cells combined with albendazole as a novel therapeutic approach for experimental neurotoxocariasis. Parasitology. vol 147. issue 7. 2021-02-16. PMID:32178741. |
interestingly, mscs combined with albendazole demonstrated a healing effect on brain inflammation, gliosis, apoptosis and significantly reduced brain damage biomarkers (s100b and gfap) and t. canis dna. |
2021-02-16 |
2023-08-13 |
mouse |
| Jaspreet Kaur, Eller Cont. Dataset on inflammation induced after lumbar puncture. Data in brief. vol 34. 2021-02-02. PMID:33521177. |
data presented in the article implicate active microglia measured by using protein biomarker such as iba-1 [1, 3] and astrocytes measured by using glial fibrillary acidic protein (gfap) [2, 3] and s100 (strongly targets s100b and weakly a1) [7, 8] in the csf collected two-three weeks after the laminectomy and dura breakage from the adult rats. |
2021-02-02 |
2023-08-13 |
rat |
| Jaspreet Kaur, Eller Cont. Dataset on inflammation induced after lumbar puncture. Data in brief. vol 34. 2021-02-02. PMID:33521177. |
western blots were performed with the collected csf which showed high expression of glial markers such as gfap, iba-1 and s100 which has shown to target s100b with no expression of a1 (or a2, play an important role in neuroprotection) astrocytes which have recently been shown to be produced by microglia at the site of injury [9]. |
2021-02-02 |
2023-08-13 |
rat |
| Serdar Çevik, Mustafa Murat Özgenç, Ahmet Güneyk, Şevket Evran, Enes Akkaya, Fatih Çalış, Salim Katar, Celaleddin Soyalp, Hakan Hanımoğlu, Mehmet Yaşar Kayna. NRGN, S100B and GFAP levels are significantly increased in patients with structural lesions resulting from mild traumatic brain injuries. Clinical neurology and neurosurgery. vol 183. 2020-11-03. PMID:31234132. |
nrgn, s100b and gfap levels are significantly increased in patients with structural lesions resulting from mild traumatic brain injuries. |
2020-11-03 |
2023-08-13 |
Not clear |
| Ping Zhang, Ying-Xue Li, Zhe-Zhe Zhang, Ye Yang, Ji-Xian Rao, Lan Xia, Xue-Yan Li, Gui-Hai Chen, Fang Wan. Astroglial Mechanisms Underlying Chronic Insomnia Disorder: A Clinical Study. Nature and science of sleep. vol 12. 2020-10-30. PMID:33117005. |
the objective of this study was to investigate whether the serum biomarkers s100 calcium binding protein b (s100b), glial fibrillary acidic protein (gfap), brain-derived neurotrophic factor (bdnf), and glial cell line-derived neurotrophic factor (gdnf) change in patients with chronic insomnia disorder (cid), and if this is the case, whether the altered levels of these serum biomarkers are associated with poor sleep quality and cognitive decline in cid. |
2020-10-30 |
2023-08-13 |
Not clear |
| Chong Di, Yun Zeng, Jingyu Mao, Zhengjie Shen, Wenzhe G. Dynamic changes and clinical significance of serum S100B protein and glial fibrillary acidic protein in patients with delayed encephalopathy after acute carbon monoxide poisoning. Pakistan journal of medical sciences. vol 34. issue 4. 2020-10-01. PMID:30190758. |
to study the dynamic changes and clinical significance of serum s100b protein and glial fibrillary acidic protein (gfap) in patients with delayed encephalopathy after acute carbon monoxide poisoning (deacmp). |
2020-10-01 |
2023-08-13 |
Not clear |