| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Olena Y Glushakova, Alexander V Glushakov, Emmy R Miller, Alex B Valadka, Ronald L Haye. Biomarkers for acute diagnosis and management of stroke in neurointensive care units. Brain circulation. vol 2. issue 1. 2020-10-01. PMID:30276272. |
s100 calcium-binding protein b (s100b), glial fibrillary acidic protein (gfap)] and neuronal cells [e.g., ubiquitin c-terminal hydrolase-l1 (uch-l1), neuron-specific enolase (nse), αii-spectrin breakdown products sbdp120, sbdp145, and sbdp150, myelin basic protein (mbp), neurofilament light chain (nf-l), tau protein, visinin-like protein-1 (vlp 1), nr2 peptide] injury that could be detected in the cerebrospinal fluid (csf) and peripheral blood might provide valuable and timely diagnostic information for stroke necessary to make prompt management and decisions, especially when the time of stroke onset cannot be determined. |
2020-10-01 |
2023-08-13 |
Not clear |
| Olena Y Glushakova, Alexander V Glushakov, Ronald L Haye. Finding effective biomarkers for pediatric traumatic brain injury. Brain circulation. vol 2. issue 3. 2020-10-01. PMID:30276288. |
however, despite the setbacks of research into s100b and mbp, investigators continue to research viable biomarkers, notably glial fibrillary acidic protein (gfap) and ubiquitin c-terminal hydrolase l1 (uch-l1), as possible aids in medical decision making. |
2020-10-01 |
2023-08-13 |
Not clear |
| Leonardo Lorent. Biomarkers Associated with the Outcome of Traumatic Brain Injury Patients. Brain sciences. vol 7. issue 11. 2020-09-30. PMID:29076989. |
this review focuses on biomarkers associated with the outcome of traumatic brain injury (tbi) patients, such as caspase-3; total antioxidant capacity; melatonin; s100b protein; glial fibrillary acidic protein (gfap); glutamate; lactate; brain-derived neurotrophic factor (bdnf); substance p; neuron-specific enolase (nse); ubiquitin carboxy-terminal hydrolase l-1 (uch-l1); tau; decanoic acid; and octanoic acid. |
2020-09-30 |
2023-08-13 |
Not clear |
| Yao-Feng Zhu, Wei-Ping Wang, Xue-Feng Zheng, Zhi Chen, Tao Chen, Zi-Yun Huang, Lin-Ju Jia, Wan-Long Le. Characteristic response of striatal astrocytes to dopamine depletion. Neural regeneration research. vol 15. issue 4. 2020-09-28. PMID:31638097. |
immunohistochemical staining was used to detect the immunoreactivity of glial fibrillary acidic protein (gfap), calcium-binding protein b (s100b), and signal transducer and activator of transcription 3 (stat3) in the striatum, and to investigate the co-expression of gfap with s100b and stat3. |
2020-09-28 |
2023-08-13 |
rat |
| Yao-Feng Zhu, Wei-Ping Wang, Xue-Feng Zheng, Zhi Chen, Tao Chen, Zi-Yun Huang, Lin-Ju Jia, Wan-Long Le. Characteristic response of striatal astrocytes to dopamine depletion. Neural regeneration research. vol 15. issue 4. 2020-09-28. PMID:31638097. |
western blot assay was used to measure the protein expression of gfap, s100b, and stat3 in the striatum. |
2020-09-28 |
2023-08-13 |
rat |
| Yao-Feng Zhu, Wei-Ping Wang, Xue-Feng Zheng, Zhi Chen, Tao Chen, Zi-Yun Huang, Lin-Ju Jia, Wan-Long Le. Characteristic response of striatal astrocytes to dopamine depletion. Neural regeneration research. vol 15. issue 4. 2020-09-28. PMID:31638097. |
striatal dopamine deprivation increased the number of gfap/s100b and gfap/stat3 double-labeled cells, and increased the protein levels of gfap, s100b, and stat3. |
2020-09-28 |
2023-08-13 |
rat |
| Vadim V Tarasov, Andrey A Svistunov, Vladimir N Chubarev, Susanna S Sologova, Polina Mukhortova, Dmitrii Levushkin, Siva G Somasundaram, Cecil E Kirkland, Sergey O Bachurin, Gjumrakch Alie. Alterations of Astrocytes in the Context of Schizophrenic Dementia. Frontiers in pharmacology. vol 10. 2020-09-28. PMID:32116664. |
the levels of the astrocyte markers (gfap, s100b) were increased unevenly in patients with schizophrenia. |
2020-09-28 |
2023-08-13 |
Not clear |
| Tejas Mehta, Muniba Fayyaz, Gema E Giler, Harleen Kaur, Sudhanshu P Raikwar, Duraisamy Kempuraj, Govindhasamy Pushpavathi Selvakumar, Mohammad Ejaz Ahmed, Ramasamy Thangavel, Smita Zaheer, Shankar Iyer, Raghav Govindarajan, Asgar Zahee. Current Trends in Biomarkers for Traumatic Brain Injury. Open access journal of neurology & neurosurgery. vol 12. issue 4. 2020-09-28. PMID:32775958. |
here, we review s100b, glial fibrillary acidic protein (gfap), neuron specific enolase (nse), myelin basic protein (mbp), ubiquitin c-terminal hydrolase l1 (uchl1), tau protein, and alpha spectrin ii break down products regarding their usefulness as a set of reliable biomarkers for the robust diagnosis of tbi. |
2020-09-28 |
2023-08-13 |
Not clear |
| Dipro Bose, Ayan Mondal, Punnag Saha, Diana Kimono, Sutapa Sarkar, Ratanesh K Seth, Patricia Janulewicz, Kimberly Sullivan, Ronnie Horner, Nancy Klimas, Mitzi Nagarkatti, Prakash Nagarkatti, Saurabh Chatterje. TLR Antagonism by Sparstolonin B Alters Microbial Signature and Modulates Gastrointestinal and Neuronal Inflammation in Gulf War Illness Preclinical Model. Brain sciences. vol 10. issue 8. 2020-09-28. PMID:32784362. |
ssnb significantly decreased astrocyte activation by decreasing colocalization of glial fibrillary acid protein (gfap) and s100 calcium-binding protein b (s100b), a crucial event in neuronal inflammation. |
2020-09-28 |
2023-08-13 |
mouse |
| Fabiana Galland, Marina Seady, Jessica Taday, Soraya Soubhi Smaili, Carlos Alberto Gonçalves, Marina Concli Leit. Astrocyte culture models: Molecular and function characterization of primary culture, immortalized astrocytes and C6 glioma cells. Neurochemistry international. vol 131. 2020-09-03. PMID:31430518. |
gfap, s100b, aqp4 and aldh1l1), although expressing them in less quantities then primary astrocyte cultures. |
2020-09-03 |
2023-08-13 |
Not clear |
| Krista Minéia Wartchow, Leticia Rodrigues, Lílian Juliana Lissner, Barbara Carolina Federhen, Nicholas Guerini Selistre, Aline Moreira, Carlos-Alberto Gonçalves, Patrícia Sesterhei. Insulin-producing cells from mesenchymal stromal cells: Protection against cognitive impairment in diabetic rats depends upon implant site. Life sciences. vol 251. 2020-05-05. PMID:32224027. |
the sc-implanted group demonstrated ameliorated cognitive impairment (evaluated by novel object recognition) and modulation of hippocampal astroglial reactivity (evaluated by s100b and gfap). |
2020-05-05 |
2023-08-13 |
rat |
| Vitor Rocco Torrez, Eduardo R Zimmer, Eduardo Kalinine, Clarissa Branco Haas, Kamila Cagliari Zenki, Alexandre Pastoris Muller, Diogo Onofre de Souza, Luis Valmor Portel. Memantine mediates astrocytic activity in response to excitotoxicity induced by PP2A inhibition. Neuroscience letters. vol 696. 2019-09-02. PMID:30586637. |
here, we aimed to analyze whether the protective effects of mn involve intrinsic astrocytic properties, particularly related to glutamate uptake and astrocytic reactivity - indexed by the expression of s100b and glial fibrillary acidic protein (gfap). |
2019-09-02 |
2023-08-13 |
rat |
| Hang-Soo Park, Hyosung Kwon, Jewon Yu, Yeonju Bae, Jae-Yong Park, Kyung-Ah Choi, Yeonho Choi, Sunghoi Hon. Precise nanoinjection delivery of plasmid DNA into a single fibroblast for direct conversion of astrocyte. Artificial cells, nanomedicine, and biotechnology. vol 46. issue sup1. 2019-08-20. PMID:29506416. |
consequently, 2500 dna molecules, no more or less, were found to be the optimal amount that dramatically increased the expression levels of the astrocyte-specific markers gfap and s100b and the demethylation gene tet1, the expression of which was sustained to maintain astrocyte functionality. |
2019-08-20 |
2023-08-13 |
mouse |
| Tao Xie, Xiaokun Jia, Mubin Che. [Gut mobility attenuation induced by antibiotics is associated with overactivation of enteric glial cells in mice]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 35. issue 3. 2019-08-15. PMID:31030711. |
real-time fluorescence quantitative pcr was used to detect the mrna levels of glial fibrillary acidic protein (gfap), glial cell-derived neurotrophic factor (gdnf), s100b and nerve growth factor (ngf), which were related to enteric glial cell activation and function both in colon and ileum. |
2019-08-15 |
2023-08-13 |
mouse |
| Hsien-Yin Liao, Ching-Liang Hsieh, Chun-Ping Huang, Yi-Wen Li. Electroacupuncture Attenuates Induction of Inflammatory Pain by Regulating Opioid and Adenosine Pathways in Mice. Scientific reports. vol 7. issue 1. 2019-07-03. PMID:29142219. |
in cfa-injected mice, a dramatic increase was observed in the expression of the following proteins in the dorsal root ganglion and spinal cord dorsal horn: the astrocytic marker gfap, s100b, rage, ppkcε, cox-2, perk, and pnfκb. |
2019-07-03 |
2023-08-13 |
mouse |
| Addison Walker, Johntaehwan Kim, Joseph Wyatt, Abby Terlouw, Kartik Balachandran, Jeffrey Wolcho. Repeated In Vitro Impact Conditioning of Astrocytes Decreases the Expression and Accumulation of Extracellular Matrix. Annals of biomedical engineering. vol 47. issue 4. 2019-06-26. PMID:30706307. |
experiments were designed to explore the effect of single and repeated impact (single vs. double) on mechano-sensitive behavior including cell viability; ecm gene (collagens i and iv, fibronectin, neurocan, versican) and reactivity gene [glial fibrillary acidic protein (gfap), s100b, vimentin] expression; matrix regulatory cytokine secretion [matrix metalloproteinase 2 (mmp-2), tissue inhibitor of metalloproteinases 1 (timp1), transforming growth factor beta 1 (tgfβ1)]; and matrix accumulation [collagen and glycosaminoglycan (gag)]. |
2019-06-26 |
2023-08-13 |
rat |
| Javad Fahanik-Babaei, Tourandokht Baluchnejadmojarad, Farnaz Nikbakht, Mehrdad Roghan. Trigonelline protects hippocampus against intracerebral Aβ(1-40) as a model of Alzheimer's disease in the rat: insights into underlying mechanisms. Metabolic brain disease. vol 34. issue 1. 2019-06-06. PMID:30421246. |
additionally, trigonelline ameliorated hippocampal levels of glial fibrillary acidic protein (gfap), s100b, cyclooxygenase 2 (cox2), tumor necrosis factor α (tnfα), and interleukin 6 (il-6) with no significant alteration of inducible nitric oxide synthase (inos). |
2019-06-06 |
2023-08-13 |
rat |
| Mohammad M Al-Qattan, Mervat M Abd-Alwahed, Medhat K Shie. Effect of TGFβ1 and nAG on Astrocyte Cultures: A Study of Astrocyte Proliferation and the Expression of GFAP, CSPG4, S100B and IL-6. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP. vol 28. issue 12. 2019-04-15. PMID:30501829. |
effect of tgfβ1 and nag on astrocyte cultures: a study of astrocyte proliferation and the expression of gfap, cspg4, s100b and il-6. |
2019-04-15 |
2023-08-13 |
Not clear |
| Mohammad M Al-Qattan, Mervat M Abd-Alwahed, Medhat K Shie. Effect of TGFβ1 and nAG on Astrocyte Cultures: A Study of Astrocyte Proliferation and the Expression of GFAP, CSPG4, S100B and IL-6. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP. vol 28. issue 12. 2019-04-15. PMID:30501829. |
to determine the effects of tgfβ1 and an anti-scar protein nag on normal (un-injured) 3-d astrocyte cultures with special emphasis on astrocyte proliferation, and the expression of gfap, cspg4, s100b, and il-6. |
2019-04-15 |
2023-08-13 |
Not clear |
| Ben Hur Marins Mussulini, Adriana Fernanda Kuckartz Vizuete, Marcos Braga, Luana Moro, Suelen Baggio, Emerson Santos, Gabriela Lazzarotto, Kamila Cagliari Zenki, Letícia Pettenuzzo, João Batista Texeira da Rocha, Diogo Losch de Oliveira, Maria Elisa Calcagnotto, José Angelo Silveira Zuanazzi, Javier Santos Burgos, Eduardo Pacheco Ric. Forebrain glutamate uptake and behavioral parameters are altered in adult zebrafish after the induction of Status Epilepticus by kainic acid. Neurotoxicology. vol 67. 2019-04-08. PMID:29680360. |
the results showed that the zebrafish suffered with lethargy while swimming for up to 72 h after se, had reduced levels of gfap cells 12 h after se, reduced levels of s100b up to 72 h after se, and reduced levels of glutamate uptake in the forebrain between 3 h and 12 h after se. |
2019-04-08 |
2023-08-13 |
human |