Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Barbara Di Benedetto, Victoria A Malik, Salina Begum, Lena Jablonowski, Gabriela B Gómez-González, Inga D Neumann, Rainer Rupprech. Fluoxetine Requires the Endfeet Protein Aquaporin-4 to Enhance Plasticity of Astrocyte Processes. Frontiers in cellular neuroscience. vol 10. 2016-02-12. PMID:26869881. |
a further evaluation of the morphology of astrocyte in brain slices (ex vivo) and in vitro using an antibody against the astrocyte-specific cytoskeletal protein glial fibrillary acidic protein (gfap) revealed that hab astrocytes extended less processes than nab cells. |
2016-02-12 |
2023-08-13 |
rat |
Barbara Di Benedetto, Victoria A Malik, Salina Begum, Lena Jablonowski, Gabriela B Gómez-González, Inga D Neumann, Rainer Rupprech. Fluoxetine Requires the Endfeet Protein Aquaporin-4 to Enhance Plasticity of Astrocyte Processes. Frontiers in cellular neuroscience. vol 10. 2016-02-12. PMID:26869881. |
nonetheless, a similar short-term treatment did neither modulate the coverage of bvs with aqp-4-positive astrocyte endfeet in nab nor in hab rats, although dosage and time of treatment were sufficient to fully recover gfap expression in hab brains. |
2016-02-12 |
2023-08-13 |
rat |
Kuang-Yao Chen, Chien-Ju Cheng, Lian-Chen Wan. Activation of Sonic Hedgehog Leads to Survival Enhancement of Astrocytes via the GRP78-Dependent Pathway in Mice Infected with Angiostrongylus cantonensis. BioMed research international. vol 2015. 2016-02-04. PMID:25961032. |
glial fibrillary acidic protein (gfap) and shh were increased in astrocyte cocultured with living fifth-stage larvae or soluble antigens. |
2016-02-04 |
2023-08-13 |
mouse |
Isabell Lebkuechner, Ulrika Wilhelmsson, Elin Möllerström, Marcela Pekna, Milos Pekn. Heterogeneity of Notch signaling in astrocytes and the effects of GFAP and vimentin deficiency. Journal of neurochemistry. vol 135. issue 2. 2016-01-11. PMID:26118771. |
we recently showed that astrocyte inhibition of neurogenesis through notch signaling depends on the intermediate filament proteins glial fibrillary acidic protein (gfap) and vimentin. |
2016-01-11 |
2023-08-13 |
mouse |
Giuseppe Battaglia, Barbara Riozzi, Domenico Bucci, Luisa Di Menna, Gemma Molinaro, Simone Pallottino, Ferdinando Nicoletti, Valeria Brun. Activation of mGlu3 metabotropic glutamate receptors enhances GDNF and GLT-1 formation in the spinal cord and rescues motor neurons in the SOD-1 mouse model of amyotrophic lateral sclerosis. Neurobiology of disease. vol 74. 2016-01-06. PMID:25434487. |
double fluorescent immunostaining showed a co-localization of gdnf with the astrocyte marker, gfap, but not with the neuronal marker, neuronal nuclear antigen (neun), or with smi-32. |
2016-01-06 |
2023-08-13 |
mouse |
Madeleine J Patience, Ihssane Zouikr, Kim Jones, Andrew N Clarkson, Jörgen Isgaard, Sarah J Johnson, Frederick R Walker, Michael Nilsso. Photothrombotic stroke induces persistent ipsilateral and contralateral astrogliosis in key cognitive control nuclei. Neurochemical research. vol 40. issue 2. 2015-12-30. PMID:25503479. |
four weeks following occlusion we collected, processed, and immunolabelled tissue using an antibody directed at the glial fibrillary acidic protein (gfap), an astrocyte specific cytoskeletal protein marker. |
2015-12-30 |
2023-08-13 |
mouse |
W Lee, J Johnson, D J Gough, J Donoghue, G L M Cagnone, V Vaghjiani, K A Brown, T G Johns, J C St Joh. Mitochondrial DNA copy number is regulated by DNA methylation and demethylation of POLGA in stem and cancer cells and their differentiated progeny. Cell death & disease. vol 6. 2015-12-22. PMID:25719248. |
glioblastoma cells treated with the dna demethylation agent 5-azacytidine over 28 days of astrocyte-induced differentiation demethylated exon 2 of polga leading to increased mtdna copy number and expression of the astrocyte endpoint marker glial fibrillary acidic protein (gfap). |
2015-12-22 |
2023-08-13 |
mouse |
Jaime L Watson, Tamara J Hala, Rajarshi Putatunda, Daniel Sannie, Angelo C Lepor. Persistent at-level thermal hyperalgesia and tactile allodynia accompany chronic neuronal and astrocyte activation in superficial dorsal horn following mouse cervical contusion spinal cord injury. PloS one. vol 9. issue 9. 2015-12-21. PMID:25268642. |
following injury, an increase in the number of neurons expressing Δfosb (a marker of chronic neuronal activation), persistent astrocyte activation and proliferation (as measured by gfap and ki67 expression), and a decrease in the expression of the astrocyte glutamate transporter glt1 are observed in the ipsilateral superficial dorsal horn of cervical spinal cord. |
2015-12-21 |
2023-08-13 |
mouse |
Holly L Johnson, Robin C Willenbring, Fang Jin, Whitney A Manhart, Stephanie J LaFrance, Istvan Pirko, Aaron J Johnso. Perforin competent CD8 T cells are sufficient to cause immune-mediated blood-brain barrier disruption. PloS one. vol 9. issue 10. 2015-12-17. PMID:25337791. |
we determined that c57bl/6 perforin-/- mice reconstituted with perforin competent cd8 t cells and induced to undergo pifs exhibited: 1) heightened cns vascular permeability, 2) increased astrocyte activation as measured by gfap expression, and 3) loss of linear organization of bbb tight junction proteins claudin-5 and occludin in areas of cns vascular permeability when compared to mock-treated controls. |
2015-12-17 |
2023-08-13 |
mouse |
Yan Fan, Khalid Amine Timani, Johnny J H. STAT3 and its phosphorylation are involved in HIV-1 Tat-induced transactivation of glial fibrillary acidic protein. Current HIV research. vol 13. issue 1. 2015-12-03. PMID:25613134. |
taken together, these findings show that stat3 is involved in and acts upstream of egr1 and p300 in the tat-induced gfap transactivation cascade and suggest important roles of stat3 in controlling astrocyte proliferation and activation in the hiv-infected central nervous system. |
2015-12-03 |
2023-08-13 |
human |
Harold A Silverman, Meghan Dancho, Angelique Regnier-Golanov, Mansoor Nasim, Mahendar Ochani, Peder S Olofsson, Mohamed Ahmed, Edmund J Miller, Sangeeta S Chavan, Eugene Golanov, Christine N Metz, Kevin J Tracey, Valentin A Pavlo. Brain region-specific alterations in the gene expression of cytokines, immune cell markers and cholinergic system components during peripheral endotoxin-induced inflammation. Molecular medicine (Cambridge, Mass.). vol 20. 2015-12-01. PMID:25299421. |
gene expression of brain gfap (astrocyte marker) was also differentially increased. |
2015-12-01 |
2023-08-13 |
mouse |
Tianqi Zhu, Donghai Yu, Jiexiong Feng, Xiaojuan Wu, Lei Xiang, Heyun Gao, Xueqin Zhang, Mingfa We. GDNF and NT-3 induce progenitor bone mesenchymal stem cell differentiation into neurons in fetal gut culture medium. Cellular and molecular neurobiology. vol 35. issue 2. 2015-11-17. PMID:25301495. |
compared to mock-transfected bmscs, gdnf and nt-3 induced bmsc differentiation to reveal neuron-like characteristics, i.e., the positive expression of neuronal marker map-2 and astrocyte marker gfap, as detected by immunofluorescence assays. |
2015-11-17 |
2023-08-13 |
rat |
Willias Masoch. Astrocyte activation in the anterior cingulate cortex and altered glutamatergic gene expression during paclitaxel-induced neuropathic pain in mice. PeerJ. vol 3. 2015-11-03. PMID:26528412. |
we examined glial fibrillary acidic protein (gfap; an astrocyte marker) immunoreactivity and gene expression of gfap, glutamate transporters and receptor subunits by real time pcr in the anterior cingulate cortex (acc) at 7 days post first administration of paclitaxel, a time point when mice had developed thermal hyperalgesia. |
2015-11-03 |
2023-08-13 |
mouse |
Srikant Rangaraju, Marla Gearing, Lee-Way Jin, Allan Leve. Potassium channel Kv1.3 is highly expressed by microglia in human Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 44. issue 3. 2015-10-26. PMID:25362031. |
in immunofluorescence studies, kv1.3 channels co-localized primarily with iba1 but not with astrocyte marker gfap, confirming that elevated kv1.3 expression is limited to microglia. |
2015-10-26 |
2023-08-13 |
human |
Todd E Morgan, Caleb E Finc. Astrocytic estrogen receptors and impaired neurotrophic responses in a rat model of perimenopause. Frontiers in aging neuroscience. vol 7. 2015-10-20. PMID:26483679. |
the corresponding loss of e2-dependent gfap repression and e2-dependent neurotrophic activity add further to the inverse relationship of gfap expression and astrocyte neurotrophic activity across aging in both sexes. |
2015-10-20 |
2023-08-13 |
rat |
Aarti Nagayach, Nisha Patro, Ishan Patr. Astrocytic and microglial response in experimentally induced diabetic rat brain. Metabolic brain disease. vol 29. issue 3. 2015-10-16. PMID:24833555. |
an increase in gfap expression sequentially from 2nd to 6th weeks of diabetes was analogous with the phenotypic changes and increased astrocyte number. |
2015-10-16 |
2023-08-13 |
rat |
Régis Gemerasca Mestriner, Lisiani Saur, Pamela Brambilla Bagatini, Pedro Porto Alegre Baptista, Sabrina Pereira Vaz, Kelly Ferreira, Susane Alves Machado, Léder Leal Xavier, Carlos Alexandre Nett. Astrocyte morphology after ischemic and hemorrhagic experimental stroke has no influence on the different recovery patterns. Behavioural brain research. vol 278. 2015-09-28. PMID:25315127. |
our results showed ischemic and hemorrhagic stroke subtypes induced similar long-term gfap-positive astrocyte plasticity (p>0.05) for all evaluated measures (regional and cellular optical density; astrocytic primary processes ramification and length; density of gfap positive astrocytes) in perilesional sensorimotor cortex and striatum. |
2015-09-28 |
2023-08-13 |
Not clear |
Ionica Pirici, Claudiu Mărgăritescu, Laurenţiu Mogoantă, Florin Petrescu, Cristiana Eugenia Simionescu, Elena Silvia Popescu, Serghei Cecoltan, Daniel Piric. Corpora amylacea in the brain form highly branched three-dimensional lattices. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 55. issue 3 Suppl. 2015-09-21. PMID:25607387. |
astrocyte gfap and aquaporin 4 signals surrounded cas, but without any colocalization with the ubiquitin areas, while perivascular cas were sometimes enclosed in pockets of the basement membranes. |
2015-09-21 |
2023-08-13 |
Not clear |
Weiyi Huang, Bingke Lv, Huijun Zeng, Dandan Shi, Yi Liu, Fanfan Chen, Feng Li, Xinghui Liu, Rong Zhu, Lei Yu, Xiaodan Jian. Paracrine Factors Secreted by MSCs Promote Astrocyte Survival Associated With GFAP Downregulation After Ischemic Stroke via p38 MAPK and JNK. Journal of cellular physiology. vol 230. issue 10. 2015-09-21. PMID:25752945. |
paracrine factors secreted by mscs promote astrocyte survival associated with gfap downregulation after ischemic stroke via p38 mapk and jnk. |
2015-09-21 |
2023-08-13 |
Not clear |
Weiyi Huang, Bingke Lv, Huijun Zeng, Dandan Shi, Yi Liu, Fanfan Chen, Feng Li, Xinghui Liu, Rong Zhu, Lei Yu, Xiaodan Jian. Paracrine Factors Secreted by MSCs Promote Astrocyte Survival Associated With GFAP Downregulation After Ischemic Stroke via p38 MAPK and JNK. Journal of cellular physiology. vol 230. issue 10. 2015-09-21. PMID:25752945. |
inhibition of p38 mapk, jnk, p53, and stat1 attenuated astrocyte injury and/or gfap upregulation. |
2015-09-21 |
2023-08-13 |
Not clear |