| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maria Soltero-Rivera, Claire Shaw, Boaz Arzi, Milinda Lommer, Bart C Weime. Feline Chronic Gingivostomatitis Diagnosis and Treatment through Transcriptomic Insights. Pathogens (Basel, Switzerland). vol 13. issue 3. 2024-03-27. PMID:38535535. |
in conjunction, the enzymes caspase 4 (casp4), matrix metalloproteinase-8 (mmp8), and prostaglandin-endoperoxide synthase 2 (ptgs2) were identified as potential biomarkers for the prediction of treatment response outcomes. |
2024-03-27 |
2024-03-29 |
Not clear |
| Cosmin Petru Peștean, Hélène Pocquet, Daria Antonia Dumitraș, Andreea Georgiana Morohoschi, Laura Cristina Ștefănuț, Sanda Andre. Correlation between Oxidative Stress Markers and Periodontal Disease in Dogs. Veterinary sciences. vol 11. issue 3. 2024-03-27. PMID:38535833. |
the antioxidant enzyme superoxide dismutase (sod), total antioxidant capacity (tac), malondialdehyde (mda) and 8-hydroxyguanosine (8ohg), matrix metalloproteinase-8 (mmp8), and the quantity of total proteins are the markers that have been investigated in order to accomplish these objectives. |
2024-03-27 |
2024-03-29 |
human |
| Yun Bai, Yichao Du, Yin Yang, Thomas Wälchli, Paul E Constanthin, Fan L. Ultrasound-Targeted Microbubble Destruction Increases BBB Permeability and Promotes Stem Cell-Induced Regeneration of Stroke by Downregulating MMP8. Cell transplantation. vol 33. 2024-01-09. PMID:38193390. |
acute cerebral infarction induced by mcao led to elevated matrix metalloproteinase 8 (mmp8) levels in the cerebrospinal fluid, which were significantly reduced following utmd-mediated bmsc treatment. |
2024-01-09 |
2024-01-10 |
rat |
| Kenzaburo Yamaji, Sadahiro Iwabuchi, Yuko Tokunaga, Shinichi Hashimoto, Daisuke Yamane, Sakiko Toyama, Risa Kono, Bouchra Kitab, Kyoko Tsukishima-Kohara, Yosuke Osawa, Yukiko Hayashi, Tsunekazu Hishima, Chise Tateno, Kiminori Kimura, Takeshi Okanoue, Michinori Kohar. Molecular insights of a CBP/β-catenin-signaling inhibitor on nonalcoholic steatohepatitis-induced liver fibrosis and disorder. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 166. 2023-08-30. PMID:37647690. |
mrna levels of the matrix metalloproteinases mmp8 and mmp9 in the liver were significantly increased, and increases in the abundance of mmp9-producing neutrophils and macrophages were observed. |
2023-08-30 |
2023-09-07 |
mouse |
| Nizar Ahmed, Devi Aru. Matrix Metalloproteinase Activity in Gingival Crevicular Fluid and Periodontal Health Status in Down Syndrome Patients: A Comparative Study. Cureus. vol 15. issue 6. 2023-07-14. PMID:37448427. |
we collected patients' complete case histories and blood samples for evaluating matrix metalloproteinase 8 (mmp8) and matrix metalloproteinase 9 (mmp9) levels. |
2023-07-14 |
2023-08-14 |
human |
| Anis Barmada, Jon Klein, Anjali Ramaswamy, Nina N Brodsky, Jillian R Jaycox, Hassan Sheikha, Kate M Jones, Victoria Habet, Melissa Campbell, Tomokazu S Sumida, Amy Kontorovich, Dusan Bogunovic, Carlos R Oliveira, Jeremy Steele, E Kevin Hall, Mario Pena-Hernandez, Valter Monteiro, Carolina Lucas, Aaron M Ring, Saad B Omer, Akiko Iwasaki, Inci Yildirim, Carrie L Luca. Cytokinopathy with aberrant cytotoxic lymphocytes and profibrotic myeloid response in SARS-CoV-2 mRNA vaccine-associated myocarditis. Science immunology. vol 8. issue 83. 2023-05-05. PMID:37146127. |
instead, unbiased systematic immune serum profiling revealed elevations in circulating interleukins (il-1β, il-1ra, and il-15), chemokines (ccl4, cxcl1, and cxcl10), and matrix metalloproteases (mmp1, mmp8, mmp9, and timp1). |
2023-05-05 |
2023-08-14 |
Not clear |
| Scott Russo, Flurin Cathomas, Hsiao-Yun Lin, Kenny Chan, Long Li, Romain Durand-de Cuttoli, Lyonna Parise, Antonio Aubry, Samer Muhareb, Fiona Desland, Yusuke Shimo, Aarthi Ramakrishnan, Molly Estill, Carmen Ferrer-Perez, Eric Parise, Jun Wang, Allison Sowa, William Janssen, Sara Costi, Adeeb Rahman, Nicolas Fernandez, Filip Swirski, Eric Nestler, Li Shen, Miriam Merad, James Murroug. Peripheral immune-derived matrix metalloproteinase promotes stress susceptibility. Research square. 2023-02-13. PMID:36778505. |
here we show that a peripheral myeloid cell-specific proteinase, matrix metalloproteinase 8 (mmp8), is elevated in serum of subjects with mdd as well as in stress-susceptible (sus) mice following chronic social defeat stress (csds). |
2023-02-13 |
2023-08-14 |
mouse |
| Sjors Maassen, Britt Coenen, Melina Ioannidis, Karl Harber, Pieter Grijpstra, Jan Van den Bossche, Geert van den Bogaar. Itaconate promotes a wound resolving phenotype in pro-inflammatory macrophages. Redox biology. vol 59. 2022-12-27. PMID:36574745. |
on the transcriptional level, 4-oi increased expression of the gene coding for tgf-β (tgfb1), whereas expression of the collagenase matrix metalloprotease-8 (mmp8) was reduced. |
2022-12-27 |
2023-08-14 |
human |
| Martina Trentini, Ilaria Zanolla, Federica Zanotti, Elena Tiengo, Danilo Licastro, Simeone Dal Monego, Luca Lovatti, Barbara Zava. Apple Derived Exosomes Improve Collagen Type I Production and Decrease MMPs during Aging of the Skin through Downregulation of the NF-κB Pathway as Mode of Action. Cells. vol 11. issue 24. 2022-12-23. PMID:36552714. |
adnvs also reduce extracellular matrix degradation by increasing collagen synthesis (col3a1, col1a2, col8a1 and col6a1) and downregulating metalloproteinase production (mmp1, mmp8 and mmp9). |
2022-12-23 |
2023-08-14 |
Not clear |
| Chengxin Zhang, Kaiyuan Niu, Meixia Ren, Xinmiao Zhou, Zhisheng Yang, Mei Yang, Xinxin Wang, Jun Luo, Yue Shao, Cheng Zhang, Dan Chen, Shan Gao, Shenglin Ge, Qingchen Wu, Qingzhong Xia. Targeted Inhibition of Matrix Metalloproteinase-8 Prevents Aortic Dissection in a Murine Model. Cells. vol 11. issue 20. 2022-10-27. PMID:36291087. |
matrix metalloproteinase-8 (mmp8) has been previously identified as a key player in atherosclerosis and arterial remodeling. |
2022-10-27 |
2023-08-14 |
mouse |
| Huan Gu, Jie Peng, Meng Wang, Zimeng Guo, Haosu Huang, Lu Ya. MicroRNA-320-3p promotes the progression of acute pancreatitis by blocking DNMT3a-mediated MMP8 methylation in a targeted manner. Molecular immunology. vol 151. 2022-09-16. PMID:36113364. |
in this research, we screened out two genes upregulated in mice with acute pancreatitis (ap) by gene sequencing: microrna (mir)-320-3p and matrix metalloprotease 8 (mmp8). |
2022-09-16 |
2023-08-14 |
mouse |
| Sakthisree Maghajothi, Lakshmi Subramanian, Preethi Mani, Mrityunjay Singh, Dhanya R Iyer, Saurabh Sharma, Madhu Khullar, Suma M Victor, Shailendra Asthana, Ajit S Mullasari, Nitish R Mahapatr. A common Matrix metalloproteinase 8 promoter haplotype enhances the risk for hypertension via diminished interactions with nuclear factor kappa B. Journal of hypertension. 2022-08-30. PMID:36040233. |
a common matrix metalloproteinase 8 promoter haplotype enhances the risk for hypertension via diminished interactions with nuclear factor kappa b. matrix metalloproteinase 8 (mmp8) has a prominent role in collagen turnover in blood vessels and vascular remodeling. |
2022-08-30 |
2023-08-14 |
Not clear |
| Yue Jiang, Xiangpan Li, Yu Yang, Jiajun Luo, Xunshan Ren, Jingwen Yuan, Qiang Ton. LncRNA HOXC-AS1 Sponges miR-99a-3p and Upregulates MMP8, Ultimately Promoting Gastric Cancer. Cancers. vol 14. issue 14. 2022-07-27. PMID:35884594. |
in addition, matrix metalloproteinase 8 (mmp8) was shown to be combined with mir-99a-3p using targetscan. |
2022-07-27 |
2023-08-14 |
Not clear |
| Laura L Coughlin, Carlos R Sanchez, Margot I Monti, John A Griffioen, Felicia B Nutter, Gillian L Beame. Potential diagnostic biomarkers for pulmonary tuberculosis in humans are not elevated in Mycobacterium tuberculosis culture-positive Asian elephants (Elephas maximus). American journal of veterinary research. vol 83. issue 8. 2022-07-27. PMID:35895781. |
to determine (1) if chemokine (c-x-c motif) ligand 1 (cxcl1), matrix metalloproteinase 8 (mmp8), interleukin-10 (il-10), interferon-γ (ifn-γ), and tumor necrosis factor-α (tnf-α) can be detected in serum from asian elephants, and (2) if their concentrations are significantly elevated in mycobacterium tuberculosis (m.tb) culture-positive elephants compared to -negative elephants. |
2022-07-27 |
2023-08-14 |
Not clear |
| Xiao Fang, Shu-Fang Duan, Zhi-Yuan Hu, Jun-Jie Wang, Le Qiu, Fei Wang, Xu-Lin Che. Inhibition of Matrix Metalloproteinase-8 Protects Against Sepsis Serum Mediated Leukocyte Adhesion. Frontiers in medicine. vol 9. 2022-02-11. PMID:35145983. |
leukocyte adhesion to vascular and matrix metalloproteinase-8 (mmp8) expression is increased in sepsis and associated with poor prognosis in sepsis patients. |
2022-02-11 |
2023-08-13 |
Not clear |
| Uwe Klinge, Axel Dievernich, Rene Tolba, Bernd Klosterhalfen, Luke Davie. CD68+ macrophages as crucial components of the foreign body reaction demonstrate an unconventional pattern of functional markers quantified by analysis with double fluorescence staining. Journal of biomedical materials research. Part B, Applied biomaterials. vol 108. issue 8. 2021-11-08. PMID:32475069. |
the list of second markers includes lymphocytes (cd3, cd4, cd8, cd16, cd56, foxp3, and cd11b) stem cells (cd34), leucocytes (cd45, cd15), macrophages (cd86, cd105, cd163, and cd206); deposition of ec matrix (collagen-i, collagen-iii, mmp2, and mmp8); ki67 as a marker for proliferation; and the tyrosine-protein kinase receptor axl. |
2021-11-08 |
2023-08-13 |
Not clear |
| Hossam El-Sheikh Ali, Shavahn C Loux, Laura Kennedy, Kirsten E Scoggin, Pouya Dini, Carleigh E Fedorka, Theodore S Kalbfleisch, Alejandro Esteller-Vico, David W Horohov, Erdal Erol, Craig N Carter, Jackie L Smith, Barry A Bal. Transcriptomic analysis of equine chorioallantois reveals immune networks and molecular mechanisms involved in nocardioform placentitis. Veterinary research. vol 52. issue 1. 2021-10-22. PMID:34238364. |
the increased leukocytic infiltration in npl was associated with the upregulation of matrix metalloproteinase (mmp1, mmp3, and mmp8) and apoptosis-related genes, such as caspases (casp3 and casp7), which could explain placental separation associated with np. |
2021-10-22 |
2023-08-13 |
Not clear |
| Wangquan Ji, Peiyu Zhu, Ruonan Liang, Liang Zhang, Yu Zhang, Yuexia Wang, Weiguo Zhang, Ling Tao, Shuaiyin Chen, Haiyan Yang, Yuefei Jin, Guangcai Dua. Coxsackievirus A2 Leads to Heart Injury in a Neonatal Mouse Model. Viruses. vol 13. issue 8. 2021-08-31. PMID:34452454. |
cva2 infection also led to the disruption of cell-matrix interactions in heart tissues, including the increases of matrix metalloproteinase (mmp)3, mmp8, mmp9, connective tissue growth factor (ctgf) and tissue inhibitors of metalloproteinases (timp)4. |
2021-08-31 |
2023-08-13 |
mouse |
| Divya Mehta, Karen Grewen, Brenda Pearson, Shivangi Wani, Leanne Wallace, Anjali K Henders, Elisabeth B Binder, Vibe G Frokjaer, Samantha Meltzer-Brody, Naomi R Wray, Alison M Stueb. Genome-wide gene expression changes in postpartum depression point towards an altered immune landscape. Translational psychiatry. vol 11. issue 1. 2021-06-28. PMID:33664235. |
these included several interesting candidates including tnfrsf17, previously reported to be significantly upregulated in women with ppd and mmp8, a matrix metalloproteinase gene, associated with depression in a genome-wide association study. |
2021-06-28 |
2023-08-13 |
Not clear |
| Nikolaos P Daskalakis, Changxin Xu, Heather N Bader, Chris Chatzinakos, Peter Weber, Iouri Makotkine, Amy Lehrner, Linda M Bierer, Elisabeth B Binder, Rachel Yehud. Intergenerational trauma is associated with expression alterations in glucocorticoid- and immune-related genes. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 4. 2021-06-23. PMID:33173192. |
the top gene across all analyses was mmp8, encoding the matrix metalloproteinase 8, which is a regulator of innate immunity. |
2021-06-23 |
2023-08-13 |
human |