| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christoph Krisp, Frank Jacobsen, Matthew J McKay, Mark P Molloy, Lars Steinstraesser, Dirk A Wolter. Proteome analysis reveals antiangiogenic environments in chronic wounds of diabetes mellitus type 2 patients. Proteomics. vol 13. issue 17. 2014-04-04. PMID:23798543. |
matrix metalloproteinases (mmps) mmp1, mmp2, and mmp8 were identified to be elevated in chronic wounds with significant impact on collagen degradation and tissue destruction. |
2014-04-04 |
2023-08-12 |
Not clear |
| Bilge Debelec-Butuner, Cansu Alapinar, Lokman Varisli, Burcu Erbaykent-Tepedelen, Syed Muhammad Hamid, Ceren Gonen-Korkmaz, Kemal Sami Korkma. Inflammation-mediated abrogation of androgen signaling: an in vitro model of prostate cell inflammation. Molecular carcinogenesis. vol 53. issue 2. 2014-03-25. PMID:22911881. |
prostate cells were then fed with cm containing varying concentrations of tnfα, and ikb degradation, nuclear factor kappa b (nfκb) translocation and transactivation, and the expression of matrix metalloproteinase-8 (mmp8) and matrix metalloproteinase-9 (mmp9) were then assessed. |
2014-03-25 |
2023-08-12 |
Not clear |
| Qingzhong Xiao, Feng Zhang, Gianluca Grassia, Yanhua Hu, Zhongyi Zhang, Qiuru Xing, Xiaoke Yin, Marcella Maddaluno, Binia Drung, Boris Schmidt, Pasquale Maffia, Armando Ialenti, Manuel Mayr, Qingbo Xu, Shu Y. Matrix metalloproteinase-8 promotes vascular smooth muscle cell proliferation and neointima formation. Arteriosclerosis, thrombosis, and vascular biology. vol 34. issue 1. 2014-02-18. PMID:24158518. |
we investigated the role of matrix metalloproteinase-8 (mmp8) in neointima formation and in vascular smooth muscle cell (vsmc) migration and proliferation. |
2014-02-18 |
2023-08-12 |
Not clear |
| Tomasz Gredes, Magdalena Wróbel-Kwiatkowska, Marzena Dominiak, Tomasz Gedrange, Christiane Kunert-Kei. Osteogenic capacity of transgenic flax scaffolds. Biomedizinische Technik. Biomedical engineering. vol 57. issue 1. 2013-11-14. PMID:22718592. |
for this, the mrna expression of genes coding for growth factors (insulin-like growth factor igf1, igf2, vascular endothelial growth factor), for osteogenic differentiation (alkaline phosphatase, osteocalcin, runx2, phex, type 1 and type 2 collagen), and for bone resorption markers [matrix metalloproteinase 8 (mmp8), acid phosphatase type 5] were analyzed using quantitative real-time polymerase chain reaction. |
2013-11-14 |
2023-08-12 |
Not clear |
| Ji-Hong Shi, Hao Guan, Shan Shi, Wei-Xia Cai, Xiao-Zhi Bai, Xiao-Long Hu, Xiao-Bin Fang, Jia-Qi Liu, Ke Tao, Xiong-Xiang Zhu, Chao-Wu Tang, Da-Hai H. Protection against TGF-β1-induced fibrosis effects of IL-10 on dermal fibroblasts and its potential therapeutics for the reduction of skin scarring. Archives of dermatological research. vol 305. issue 4. 2013-10-22. PMID:23321694. |
in this study, human dermal fibroblasts stimulated with tgf-β1 were treated with il-10 to analyze the mrna and some of proteins' expression levels of type i collagen (col1), type iii collagen (col3), alpha-smooth muscle actin (α-sma), matrix metalloproteinase-1 (mmp1), mmp2, mmp8 and tissue inhibitor of metalloproteinase 1 (timp1), timp2 by real-time pcr and western blot, to observe α-sma-positive fibroblasts by immunocytochemistry. |
2013-10-22 |
2023-08-12 |
human |
| Yumi Imai, Siobhan Boyle, Gladys M Varela, Emilie Caron, Xiaoyan Yin, Raina Dhir, Ravindra Dhir, Mark J Graham, Rexford S Ahim. Effects of perilipin 2 antisense oligonucleotide treatment on hepatic lipid metabolism and gene expression. Physiological genomics. vol 44. issue 22. 2013-05-03. PMID:23012396. |
plin2-aso also increased the expression of genes involved in regulation of hepatocyte proliferation (afp, h19), mitosis (ccna2, incenp, sgol1), and extracellular matrix (col1a1, col3a1, mmp8). |
2013-05-03 |
2023-08-12 |
mouse |
| Maria Schache, Paul N Bair. Assessment of the association of matrix metalloproteinases with myopia, refractive error and ocular biometric measures in an Australian cohort. PloS one. vol 7. issue 10. 2013-03-28. PMID:23077567. |
the matrix metalloproteinases (mmps) falling into the collagenase (mmp1, mmp8, mmp13), gelatinase (mmp2, mmp9) and stromelysin (mmp3, mmp10, mmp11) functional groups are particularly important. |
2013-03-28 |
2023-08-12 |
Not clear |
| Dominik Domanski, Gabriela V Cohen Freue, Luis Sojo, Michael A Kuzyk, Leslie Ratkay, Carol E Parker, Y Paul Goldberg, Christoph H Borcher. The use of multiplexed MRM for the discovery of biomarkers to differentiate iron-deficiency anemia from anemia of inflammation. Journal of proteomics. vol 75. issue 12. 2012-11-07. PMID:22146476. |
based on this study, we were able to identify a panel of 8 biomarker proteins: apolipoprotein a4 (apo4), transferrin, transferrin receptor 1, ceruloplasmin, haptoglobin, lactoferrin, hemopexin, and matrix metalloproteinase-8 (mmp8) that clearly distinguish among the normal and disease models. |
2012-11-07 |
2023-08-12 |
mouse |
| Roosmarijn E Vandenbroucke, Eline Dejonckheere, Philippe Van Lint, Delphine Demeestere, Elien Van Wonterghem, Ineke Vanlaere, Leen Puimège, Filip Van Hauwermeiren, Riet De Rycke, Conor Mc Guire, Cristina Campestre, Carlos López-Otin, Patrick Matthys, Georges Leclercq, Claude Liber. Matrix metalloprotease 8-dependent extracellular matrix cleavage at the blood-CSF barrier contributes to lethality during systemic inflammatory diseases. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 29. 2012-10-24. PMID:22815495. |
we report that matrix metalloprotease-8 (mmp8) depletion or inhibition protects mice from death and hypothermia in sepsis and renal ischemia/reperfusion. |
2012-10-24 |
2023-08-12 |
mouse |
| L Izakovicova Holla, B Hrdlickova, J Vokurka, A Fassman. Matrix metalloproteinase 8 (MMP8) gene polymorphisms in chronic periodontitis. Archives of oral biology. vol 57. issue 2. 2012-05-17. PMID:21920499. |
matrix metalloproteinase 8 (mmp8) gene polymorphisms in chronic periodontitis. |
2012-05-17 |
2023-08-12 |
Not clear |
| Christopher S Muratore, Mark W Harty, Elaine F Papa, Thomas F Trac. Dexamethasone alters the hepatic inflammatory cellular profile without changes in matrix degradation during liver repair following biliary decompression. The Journal of surgical research. vol 156. issue 2. 2009-09-25. PMID:19592011. |
we have previously shown in a reversible model of cholestatic injury that repair is mediated by macrophages, neutrophils, and specific matrix metalloproteinase activity (mmp8); we questioned whether steroids would alter these intrinsic mechanisms. |
2009-09-25 |
2023-08-12 |
Not clear |
| Lavanya H Palavalli, Todd D Prickett, John R Wunderlich, Xiaomu Wei, Allison S Burrell, Patricia Porter-Gill, Sean Davis, Chenwei Wang, Julia C Cronin, Neena S Agrawal, Jimmy C Lin, Wendy Westbroek, Shelley Hoogstraten-Miller, Alfredo A Molinolo, Patricia Fetsch, Armando C Filie, Michael P O'Connell, Carolyn E Banister, Jason D Howard, Phillip Buckhaults, Ashani T Weeraratna, Lawrence C Brody, Steven A Rosenberg, Yardena Samuel. Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma. Nature genetics. vol 41. issue 5. 2009-06-29. PMID:19330028. |
analysis of the matrix metalloproteinase family reveals that mmp8 is often mutated in melanoma. |
2009-06-29 |
2023-08-12 |
human |
| Patricia González-Arriaga, M Felicitas López-Cima, Ana Fernández-Somoano, Teresa Pascual, Manuel G Marrón, Xose S Puente, Adonina Tardó. Polymorphism +17 C/G in matrix metalloprotease MMP8 decreases lung cancer risk. BMC cancer. vol 8. 2009-02-19. PMID:19094243. |
polymorphism +17 c/g in matrix metalloprotease mmp8 decreases lung cancer risk. |
2009-02-19 |
2023-08-12 |
human |
| Tiziano Tuccinardi, Elisa Nuti, Gabriella Ortore, Armando Rossello, Stanislava I Avramova, Adriano Martinell. Development of a receptor-based 3D-QSAR study for the analysis of MMP2, MMP3, and MMP9 inhibitors. Bioorganic & medicinal chemistry. vol 16. issue 16. 2008-10-29. PMID:18640045. |
the ability of gold software to predict the binding disposition of matrix metalloproteinase (mmp) inhibitors was evaluated using mmp3 and mmp8. |
2008-10-29 |
2023-08-12 |
Not clear |
| Julie Decock, Ji-Rong Long, Ross C Laxton, Xiao-Ou Shu, Conrad Hodgkinson, Wouter Hendrickx, Eve G Pearce, Yu-Tang Gao, Andresa C Pereira, Robert Paridaens, Wei Zheng, Shu Y. Association of matrix metalloproteinase-8 gene variation with breast cancer prognosis. Cancer research. vol 67. issue 21. 2007-11-27. PMID:17974962. |
animal and cell studies indicate an inhibitory effect of matrix metalloproteinase-8 (mmp8) on tumorigenesis and metastasis. |
2007-11-27 |
2023-08-12 |
Not clear |
| Hongyan Wang, Samuel Parry, George Macones, Mary D Sammel, Pedro E Ferrand, Helena Kuivaniemi, Gerard Tromp, Indrani Halder, Mark D Shriver, Roberto Romero, Jerome F Straus. Functionally significant SNP MMP8 promoter haplotypes and preterm premature rupture of membranes (PPROM). Human molecular genetics. vol 13. issue 21. 2005-05-17. PMID:15367487. |
matrix metalloproteinase 8 (mmp8), an enzyme that degrades fibrillar collagens imparting strength to the fetal membranes, is expressed by leukocytes and chorionic cytotrophoblast cells. |
2005-05-17 |
2023-08-12 |
Not clear |
| J Garcia-Bañuelos, F Siller-Lopez, A Miranda, L K Aguilar, E Aguilar-Cordova, J Armendariz-Borund. Cirrhotic rat livers with extensive fibrosis can be safely transduced with clinical-grade adenoviral vectors. Evidence of cirrhosis reversion. Gene therapy. vol 9. issue 2. 2002-03-12. PMID:11857071. |
although there was an important increase in liver enzymes between the first 48 h after adenovirus injection in cirrhotic animals compared to non-transduced cirrhotic rats, this hepatic damage was resolved after 72-96 h. then, the cdna for neutrophil collagenase, also known as matrix metalloproteinase 8 (mmp8), was cloned in an ad-vector and delivered to cirrhotic rat livers being able to reverse fibrosis in 44%. |
2002-03-12 |
2023-08-12 |
human |
| J C Müller, E G von Roedern, F Grams, H Nagase, L Morode. Non-peptidic cysteine derivatives as inhibitors of matrix metalloproteinases. Biological chemistry. vol 378. issue 12. 1998-03-18. PMID:9461346. |
by exploiting the thiol function of l-cysteine as a chelating group of the active-site zinc atom of matrix metalloproteinases (mmps), n- and c-terminal derivatization of this amino acid with aliphatic and aromatic groups allowed us to explore the selectivity of the s and/or s' binding subsites of human neutrophil collagenase (mmp8) and stromelysin (mmp3). |
1998-03-18 |
2023-08-12 |
human |