| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zenon Pidsudk. Immunohistochemical characteristics and distribution of neurons in the paravertebral, prevertebral and pelvic ganglia supplying the urinary bladder in the male pig. Journal of molecular neuroscience : MN. vol 52. issue 1. 2014-09-25. PMID:24122239. |
the combined retrograde tracing and immunohistochemistry for tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), neuropeptide y (npy), somatostatin(som), galanin (gal), vasoactive intestinal polypeptide(vip), nitric oxide synthase (nos), calcitonin gene related peptide (cgrp), substance p (sp), choline acetyltransferase (chat) and vesicular acetylcholine transporter(vacht) were applied in the experiment. |
2014-09-25 |
2023-08-12 |
Not clear |
| Z Pidsudk. Immunohistochemical characteristics and distribution of neurons in the intramural ganglia supplying the urinary bladder in the male pig. Polish journal of veterinary sciences. vol 16. issue 4. 2014-04-03. PMID:24597296. |
twelve tm-thick cryostat sections were processed for double-labelling immunofluorescence with antibodies against tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), neuropeptide y (npy), somatostatin (som), galanin (gal), vasoactive intestinal polypeptide (vip), nitric oxide synthase (nos), calcitonin gene-related peptide (cgrp), substance p (sp) and vesicular acetylcholine transporter (vacht). |
2014-04-03 |
2023-08-12 |
Not clear |
| Joanna Wojtkiewicz, Maciej Równiak, Robert Crayton, Sławomir Gonkowski, Anna Robak, Michal Zalecki, Mariusz Majewski, Lars Klimaschewsk. Axotomy-induced changes in the chemical coding pattern of colon projecting calbindin-positive neurons in the inferior mesenteric ganglia of the pig. Journal of molecular neuroscience : MN. vol 51. issue 1. 2014-03-12. PMID:23546647. |
all animals were euthanized and the inferior mesenteric ganglia were harvested and processed for double-labeling immunofluorescence for calbindin-d28k (cb) in combination with either tyrosine hydroxylase (th), neuropeptide y (npy), somatostatin (som), vasoactive intestinal polypeptide (vip), nitric oxide synthase (nos), leu-enkephalin (lenk), substance p, vesicular acetylcholine transporter, or galanin. |
2014-03-12 |
2023-08-12 |
Not clear |
| Julia Shanks, Neil Herrin. Peripheral cardiac sympathetic hyperactivity in cardiovascular disease: role of neuropeptides. American journal of physiology. Regulatory, integrative and comparative physiology. vol 305. issue 12. 2014-02-13. PMID:24005254. |
recent data demonstrates a direct action of the sympathetic cotransmitters neuropeptide y (npy) and galanin on the ability of the vagus to release acetylcholine and control heart rate. |
2014-02-13 |
2023-08-12 |
rat |
| L Ragionieri, M Botti, F Gazza, C Sorteni, R Chiocchetti, P Clavenzani, L Bo Minelli, R Pan. Localization of peripheral autonomic neurons innervating the boar urinary bladder trigone and neurochemical features of the sympathetic component. European journal of histochemistry : EJH. vol 57. issue 2. 2014-01-22. PMID:23807295. |
stg and cmg fb+ neurons were immunoreactive (ir) for tyrosine hydroxylase (th) (66±10.1% and 52.7±8.2%, respectively), dopamine beta-hydroxylase (dβh) (62±6.2% and 52±6.2%, respectively), neuropeptide y (npy) (59±8.2% and 65.8±7.3%, respectively), calcitonin-gene-related peptide (cgrp) (24.1±3.3% and 22.1±3.3%, respectively), substance p (sp) (21.6±2.4% and 37.7±7.5%, respectively), vasoactive intestinal polypeptide (vip) (18.9±2.3% and 35.4±4.4%, respectively), neuronal nitric oxide synthase (nnos) (15.3±2% and 32.9±7.7%, respectively), vesicular acetylcholine transporter (vacht) (15±2% and 34.7±4.5%, respectively), leu-enkephalin (lenk) (14.3±7.1% and 25.9±8.9%, respectively), and somatostatin (som) (12.4±3% and 31.8±7.3%, respectively). |
2014-01-22 |
2023-08-12 |
Not clear |
| Joanna Wojtkiewicz, Maciej Równiak, Robert Crayton, Mariusz Majewski, Sławomir Gonkowsk. Chemical coding of zinc-enriched neurons in the intramural ganglia of the porcine jejunum. Cell and tissue research. vol 350. issue 2. 2013-06-12. PMID:22918698. |
cryostat sections (10 mμ thick) of porcine jejunum were processed for routine double- and triple-immunofluorescence labeling for znt3 in various combinations with immunolabeling for other neurochemicals including pan-neuronal marker (pgp9.5), substance p (sp), somatostatin (som), vasoactive intestinal peptide (vip), nitric oxide synthase (nos), leu-enkephalin (lenk), vesicular acetylcholine transporter (vacht), neuropeptide y (npy), galanin (gal), and calcitonin-gene related peptide (cgrp). |
2013-06-12 |
2023-08-12 |
Not clear |
| Joanna Wojtkiewicz, Maciej Równiak, Sławomir Gonkowski, Robert Crayton, Mariusz Majewski, Anna Robak, Joanna Białkowska, Monika Barczewsk. Proliferative enteropathy (PE)-induced changes in the calbindin-immunoreactive (CB-IR) neurons of inferior mesenteric ganglion supplying the descending colon in the pig. Journal of molecular neuroscience : MN. vol 48. issue 3. 2013-04-19. PMID:22170039. |
the retrograde tracer fast blue (fb) was injected into the descending colons of all animals and then tissue comprising imgs from both groups was processed for double-labeling immunofluorescence with calbindin-d28k (cb) in combination with either tyrosine hydroxylase (th), neuropeptide y (npy), somatostatin (som), vasoactive intestinal polypeptide (vip), nitric oxide synthase, leu-enkephalin, substance p, vesicular acetylcholine transporter, galanin, or pituitary adenylate cyclase-activating polypeptide. |
2013-04-19 |
2023-08-12 |
Not clear |
| Joanna Wojtkiewicz, Maciej Równiak, Robert Crayton, Monika Barczewska, Marek Bladowski, Anna Robak, Zenon Pidsudko, Mariusz Majewsk. Inflammation-induced changes in the chemical coding pattern of colon-projecting neurons in the inferior mesenteric ganglia of the pig. Journal of molecular neuroscience : MN. vol 46. issue 2. 2012-09-14. PMID:21826392. |
the animals were euthanized and the inferior mesenteric ganglion was harvested and processed for double-labeling immunofluorescence for calbindin-d28k (cb) in combination with either tyrosine hydroxylase (th), neuropeptide y (npy), somatostatin (som), vasoactive intestinal polypeptide (vip), nitric oxide synthase (nos), leu-enkephalin (lenk), substance p (sp), vesicular acetylcholine transporter (vacht), or galanin (gal). |
2012-09-14 |
2023-08-12 |
Not clear |
| Neil Herring, James Cranley, Michael N Lokale, Dan Li, Julia Shanks, Eric N Alston, Beatrice M Girard, Emma Carter, Rodney L Parsons, Beth A Habecker, David J Paterso. The cardiac sympathetic co-transmitter galanin reduces acetylcholine release and vagal bradycardia: implications for neural control of cardiac excitability. Journal of molecular and cellular cardiology. vol 52. issue 3. 2012-07-09. PMID:22172449. |
moreover we hypothesize that galanin acts similarly to npy by reducing vagal acetylcholine release via a receptor mediated, protein kinase-dependent pathway. |
2012-07-09 |
2023-08-12 |
Not clear |
| Neil Herring, James Cranley, Michael N Lokale, Dan Li, Julia Shanks, Eric N Alston, Beatrice M Girard, Emma Carter, Rodney L Parsons, Beth A Habecker, David J Paterso. The cardiac sympathetic co-transmitter galanin reduces acetylcholine release and vagal bradycardia: implications for neural control of cardiac excitability. Journal of molecular and cellular cardiology. vol 52. issue 3. 2012-07-09. PMID:22172449. |
these results demonstrate that prolonged sympathetic activation releases the slowly diffusing adrenergic co-transmitter galanin in addition to npy, and that this contributes to the attenuation in vagal bradycardia via a reduction in acetylcholine release. |
2012-07-09 |
2023-08-12 |
Not clear |
| A J McDonald, F Mascagn. Neuronal localization of M2 muscarinic receptor immunoreactivity in the rat amygdala. Neuroscience. vol 196. 2012-02-23. PMID:21875654. |
these findings indicate that acetylcholine can modulate a variety of discrete neuronal subpopulations in various amygdalar nuclei via m2rs, especially neurons that express som and npy. |
2012-02-23 |
2023-08-12 |
rat |
| A Vega, J A Luther, S J Birren, M A Morale. Segregation of the classical transmitters norepinephrine and acetylcholine and the neuropeptide Y in sympathetic neurons: modulation by ciliary neurotrophic factor or prolonged growth in culture. Developmental neurobiology. vol 70. issue 14. 2011-02-25. PMID:20715153. |
we addressed this question by exploring the segregation pattern of the classical sympathetic transmitters norepinephrine (ne) and acetylcholine (ach) and the cotransmitter neuropeptide y (npy) in sympathetic ganglionic neurons cocultured with cardiac myocytes. |
2011-02-25 |
2023-08-12 |
Not clear |
| A Vega, J A Luther, S J Birren, M A Morale. Segregation of the classical transmitters norepinephrine and acetylcholine and the neuropeptide Y in sympathetic neurons: modulation by ciliary neurotrophic factor or prolonged growth in culture. Developmental neurobiology. vol 70. issue 14. 2011-02-25. PMID:20715153. |
using antibodies against npy and the vesicular ne and ach transporters vmat2 and vesicular acetylcholine transporter (vacht), we investigated the effect of ciliary neurotrophic factor (cntf) or long (three weeks) culture periods on the segregation of vmat2, vacht, and npy to separate varicosities. |
2011-02-25 |
2023-08-12 |
Not clear |
| Mariusz Gajda, Jan A Litwin, Zbigniew Tabarowski, Olaf Zagólski, Tadeusz Cichocki, Jean-Pierre Timmermans, Dirk Adriaense. Development of rat tibia innervation: colocalization of autonomic nerve fiber markers with growth-associated protein 43. Cells, tissues, organs. vol 191. issue 6. 2010-11-03. PMID:20090303. |
double immunofluorescence combined with confocal microscopy was applied to study colocalization of neuronal growth- associated protein 43 (gap-43) and panneuronal marker protein gene product 9.5 (pgp) with markers of the autonomic nervous system: neuropeptide y (npy) and dopamine beta-hydroxylase (dbetah) for adrenergic, as well as vasoactive intestinal polypeptide (vip) and vesicular acetylcholine transporter (vacht) for cholinergic fibers. |
2010-11-03 |
2023-08-12 |
rat |
| Lorenzo Leggio, Silvia Cardone, Anna Ferrulli, George A Kenna, Marco Diana, Robert M Swift, Giovanni Addolorat. Turning the clock ahead: potential preclinical and clinical neuropharmacological targets for alcohol dependence. Current pharmaceutical design. vol 16. issue 19. 2010-10-08. PMID:20482506. |
a variety of systems have been investigated, such as the endocannabinoid system, modulators of glutamatergic transmission, corticotropin-releasing factor (crf), neuropeptide y (npy), nociceptin, glial cell line-derived neurotrophic factor (gdnf), acetaldehyde (acd), substance p and neurokinin 1 (nk1) receptor, nicotinic acetylcholine receptors (nachrs), alpha-adrenergic receptor, and many others. |
2010-10-08 |
2023-08-12 |
human |
| D De Fontgalland, D A Wattchow, M Costa, S J H Brooke. Immunohistochemical characterization of the innervation of human colonic mesenteric and submucosal blood vessels. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. vol 20. issue 11. 2009-03-03. PMID:18643894. |
mesenteric and submucosal vessels were processed for double-labelling immunohistochemical localization of tyrosine hydroxylase (th), neuropeptide y (npy), calcitonin gene-related peptide (cgrp), substance p (sp), vasoactive intestinal polypeptide (vip), nitric oxide synthase (nos), somatostatin (som), vesicular acetylcholine transporter (vacht) and enkephelin (enk), each compared to the pan-neuronal marker protein gene product 9.5. |
2009-03-03 |
2023-08-12 |
human |
| Neil Herring, Michael N Lokale, Edward J Danson, Daniel A Heaton, David J Paterso. Neuropeptide Y reduces acetylcholine release and vagal bradycardia via a Y2 receptor-mediated, protein kinase C-dependent pathway. Journal of molecular and cellular cardiology. vol 44. issue 3. 2008-08-04. PMID:17996892. |
we tested the hypothesis that npy reduces acetylcholine release, at similar concentrations to which it attenuates vagal bradycardia, via pre-synaptic y2 receptors modulating a pathway that is dependent on protein kinase a (pka) or protein kinase c (pkc). |
2008-08-04 |
2023-08-12 |
Not clear |
| Neil Herring, Michael N Lokale, Edward J Danson, Daniel A Heaton, David J Paterso. Neuropeptide Y reduces acetylcholine release and vagal bradycardia via a Y2 receptor-mediated, protein kinase C-dependent pathway. Journal of molecular and cellular cardiology. vol 44. issue 3. 2008-08-04. PMID:17996892. |
npy reduced the heart rate response to vagal stimulation at 1, 3 and 5 hz (significant at 100 nm and reaching a plateau at 250 nm npy, p<0.05, n=6) but not to the stable analogue of acetylcholine, carbamylcholine (30, 60 or 90 nm, n=6) which produced similar degrees of bradycardia. |
2008-08-04 |
2023-08-12 |
Not clear |
| Neil Herring, Michael N Lokale, Edward J Danson, Daniel A Heaton, David J Paterso. Neuropeptide Y reduces acetylcholine release and vagal bradycardia via a Y2 receptor-mediated, protein kinase C-dependent pathway. Journal of molecular and cellular cardiology. vol 44. issue 3. 2008-08-04. PMID:17996892. |
these results show that npy attenuates vagal bradycardia via a pre-synaptic decrease in acetylcholine release that appears to be mediated by a y2 receptor pathway involving modulation of pkc. |
2008-08-04 |
2023-08-12 |
Not clear |
| Maria Sörhede Winzell, Bo Ahré. G-protein-coupled receptors and islet function-implications for treatment of type 2 diabetes. Pharmacology & therapeutics. vol 116. issue 3. 2008-02-15. PMID:17900700. |
examples of islet gpcr are gpr40 and gpr119, which are gpcr with fatty acids as ligands, the receptors for the incretin hormones glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip), the receptors for the islet hormones glucagon and somatostatin, the receptors for the classical neurotransmittors acetylcholine (ach; m(3) muscarinic receptors) and noradrenaline (beta(2)- and alpha(2)-adrenoceptors) and for the neuropeptides pituitary adenylate cyclase-activating polypeptide (pacap) and vasoactive intestinal polypeptide (vip; pac(1) and vpac(2) receptors), cholecystokinin (cck(a) receptors) and neuropeptide y (npy y1 receptors). |
2008-02-15 |
2023-08-12 |
Not clear |