| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Genovese, M Chiariello, M Bozzaotre, S Latte, W De Alfieri, M Condorell. Adrenergic activity as a modulating factor in the genesis of myocardial hypertrophy in the rat. Experimental and molecular pathology. vol 41. issue 3. 1985-02-01. PMID:6239790. |
data are presented indicating that both exogenous catecholamines (i.e., isoproterenol) and endogenous catecholamines (released from tyramine) are able to bring about a degree of myocardial hypertrophy associated with a significant increase in the ventricular concentrations of hydroxyproline, without affecting hemodynamic parameters (blood pressures and heart rate). |
1985-02-01 |
2023-08-12 |
rat |
| Q Tang, P B Taylo. Regression of isoproterenol-induced cardiac hypertrophy. Canadian journal of physiology and pharmacology. vol 62. issue 9. 1985-01-14. PMID:6208988. |
cardiac hypertrophy was induced in adult female wistar rats after 8 days of daily subcutaneous injections of isoproterenol (iso). |
1985-01-14 |
2023-08-12 |
rat |
| M G Humphreys-Behe. Isoprenaline-induced changes in rat parotid and submandibular glands are age- and dosage-dependent. The Biochemical journal. vol 221. issue 1. 1984-09-17. PMID:6466311. |
gland hypertrophy showed the same differential dosage kinetics, based on gland weight, between the two glands; however, hypertrophy could be accomplished at a lower dosage of isoprenaline than that used to induce proline-rich-protein biosynthesis. |
1984-09-17 |
2023-08-12 |
rat |
| P B Taylor, Q Tan. Development of isoproterenol-induced cardiac hypertrophy. Canadian journal of physiology and pharmacology. vol 62. issue 4. 1984-08-15. PMID:6203632. |
the development of cardiac hypertrophy was studied in adult female wistar rats following daily subcutaneous injections of isoproterenol (iso) (0.3 mg/kg body weight). |
1984-08-15 |
2023-08-12 |
rat |
| A Genovese, S Latte, S Betocchi, M Bozzaotre, A Giunta, M Chiariell. Cardiac hypertrophy in the absence of pressure overload: an experimental and clinical report. Clinical and experimental pharmacology & physiology. vol 11. issue 1. 1984-06-19. PMID:6232026. |
chronic adrenergic stimulation performed in the rat treated with low doses of isoprenaline (a direct stimulating adrenergic drug) or with tyramine (primarily a releaser of endogenous catecholamines) induced hypertrophy of the right ventricle, left ventricle, and interventricular septum without modifying the haemodynamic parameters mentioned above. |
1984-06-19 |
2023-08-12 |
rat |
| D E Vatner, C J Homcy, S P Sit, W T Manders, S F Vatne. Effects of pressure overload, left ventricular hypertrophy on beta-adrenergic receptors, and responsiveness to catecholamines. The Journal of clinical investigation. vol 73. issue 5. 1984-06-05. PMID:6325505. |
in both normal and lv hypertrophy groups, increasing bolus doses of norepinephrine or isoproterenol produced equivalent changes in lv dp/dt. |
1984-06-05 |
2023-08-12 |
Not clear |
| O Petko. Some functional changes in experimentally induced cardiac overload. Acta physiologica et pharmacologica Bulgarica. vol 9. issue 3. 1984-04-11. PMID:6230880. |
in connection with the elucidation of the mechanisms of the acute and chronic haemodynamic stress during cardiac overloading, as well as in investigations on the role of neurotransmitter systems in the genesis of myocardial hypertrophy (mh), we carried out a complex of studies involving modelling of mh induced by treatment of rats with isoprenaline (iso.) |
1984-04-11 |
2023-08-12 |
rat |
| K Clarke, L C War. Protein synthesis in the early stages of cardiac hypertrophy. The International journal of biochemistry. vol 15. issue 10. 1983-12-17. PMID:6195031. |
cardiac hypertrophy, induced in rats by either tri-iodothyronine or isoproterenol, administered daily for 7 days, was monitored using several parameters. |
1983-12-17 |
2023-08-12 |
rat |
| M Raymondjean, B Kneip, J Kru. Early molecular events in rat heart after administration of triiodothyronine and isoproterenol. Biochimica et biophysica acta. vol 741. issue 1. 1983-11-23. PMID:6193811. |
triiodothyronine (t3), isoproterenol and aminophylline injected daily into rats induce heart hypertrophy. |
1983-11-23 |
2023-08-12 |
rat |
| N L O'dell, M Sharawy, C B Penningto. Effects of prior culture or isoproterenol injections on the regeneration of rat submandibular gland autografts. The Anatomical record. vol 206. issue 1. 1983-09-20. PMID:6881548. |
lastly, isoproterenol appeared to accelerate the regenerative response in some of the direct smg autografts, and the drug caused acinar cell hypertrophy in two of the direct smg autografts. |
1983-09-20 |
2023-08-12 |
rat |
| A Ray, J Aussedat, J Olivares, A Ross. Comparative changes in the 32P labeling of adenine and uracil nucleotides in the hypertrophying rat heart. Advances in myocardiology. vol 4. 1983-07-08. PMID:6190204. |
cardiac hypertrophy was induced either by chronic isoproterenol treatment (5 mg x kg-1 body wt. |
1983-07-08 |
2023-08-12 |
rat |
| A Ray, J Aussedat, J Olivares, A Ross. Comparative changes in the 32P labeling of adenine and uracil nucleotides in the hypertrophying rat heart. Advances in myocardiology. vol 4. 1983-07-08. PMID:6190204. |
in this experimental model (isoproterenol treatment), the hypertrophy develops faster and is accompanied by a larger increase in cardiac rna concentration. |
1983-07-08 |
2023-08-12 |
rat |
| G Gullace, M Knippel, P Ravizza, M T Savoi. Echocardiographic assessment of left ventricular wall motion in hypertrophic cardiomyopathy. Giornale italiano di cardiologia. vol 12. issue 8. 1983-06-23. PMID:6892016. |
m-mode and two-dimensional parasternal long axis view echocardiography, and left anterior oblique cineangiography were employed to assess the left ventricular wall motion in 10 normal subjects (n) and in 25 patients with hypertrophic cardiomyopathy: 7 patients with symmetric hypertrophy (sh) and 6 patients with apical cardiomyopathy (ahcm) and no intraventricular gradient; 12 patients with hypertrophic obstructive cardiomyopathy and asymmetric septal hypertrophy with resting intraventricular gradient (6 pts) (hocm-r) or gradient occurring only after isoproterenol infusion (6 pts) (hocm-i). |
1983-06-23 |
2023-08-12 |
human |
| A Perin, A Sessa, M A Desideri. Polyamine levels and diamine oxidase activity in hypertrophic heart of spontaneously hypertensive rats and of rats treated with isoproterenol. Biochimica et biophysica acta. vol 755. issue 3. 1983-04-15. PMID:6218830. |
polyamine levels and diamine oxidase activity in hypertrophic heart of spontaneously hypertensive rats and of rats treated with isoproterenol. |
1983-04-15 |
2023-08-12 |
rat |
| A Perin, A Sessa, M A Desideri. Polyamine levels and diamine oxidase activity in hypertrophic heart of spontaneously hypertensive rats and of rats treated with isoproterenol. Biochimica et biophysica acta. vol 755. issue 3. 1983-04-15. PMID:6218830. |
polyamine levels and diamine oxidase (ec 1.4.3.6) activity were studied in hypertrophic heart of spontaneously hypertensive rats as well as in the heart of wistar rats during the development and regression of cardiac hypertrophy induced by isoproterenol administration. |
1983-04-15 |
2023-08-12 |
rat |
| A Perin, A Sessa, M A Desideri. Polyamine levels and diamine oxidase activity in hypertrophic heart of spontaneously hypertensive rats and of rats treated with isoproterenol. Biochimica et biophysica acta. vol 755. issue 3. 1983-04-15. PMID:6218830. |
during the development of cardiac hypertrophy induced by isoproterenol, there was an increase in polyamine content and diamine oxidase activity. |
1983-04-15 |
2023-08-12 |
rat |
| A Perin, A Sessa, M A Desideri. Polyamine levels and diamine oxidase activity in hypertrophic heart of spontaneously hypertensive rats and of rats treated with isoproterenol. Biochimica et biophysica acta. vol 755. issue 3. 1983-04-15. PMID:6218830. |
following the cessation of isoproterenol treatment, cardiac hypertrophy regressed and polyamine levels and diamine oxidase activity diminished toward control values. |
1983-04-15 |
2023-08-12 |
rat |
| F A Sreter, R Faris, I Balogh, E Somogyi, P Sotony. Changes in myosin isozyme distribution induced by low doses of isoproterenol. Archives internationales de pharmacodynamie et de therapie. vol 260. issue 1. 1983-04-07. PMID:6219644. |
thus low doses of isoproterenol produce hypertrophy with an isozyme pattern similar to that found in young (approximately 4-6 weeks old) rats. |
1983-04-07 |
2023-08-12 |
rat |
| R Sung, M Stephens, L Blayney, A Henderso. Cardiac hypertrophy and its regression in rat: comparison of morphological changes in response to aortic constriction, iron deficiency anaemia and isoprenaline. Journal of molecular and cellular cardiology. vol 14. issue 9. 1983-02-14. PMID:6217348. |
cardiac hypertrophy and its regression in rat: comparison of morphological changes in response to aortic constriction, iron deficiency anaemia and isoprenaline. |
1983-02-14 |
2023-08-12 |
rat |
| P Simpson, A McGrath, S Savio. Myocyte hypertrophy in neonatal rat heart cultures and its regulation by serum and by catecholamines. Circulation research. vol 51. issue 6. 1983-01-27. PMID:6216022. |
chronic exposure to isoproterenol or norepinephrine (1 microm) significantly stimulated myocardial cell hypertrophy. |
1983-01-27 |
2023-08-12 |
rat |